Motif ID: Gata4

Z-value: 0.894


Transcription factors associated with Gata4:

Gene SymbolEntrez IDGene Name
Gata4 ENSMUSG00000021944.9 Gata4



Activity profile for motif Gata4.

activity profile for motif Gata4


Sorted Z-values histogram for motif Gata4

Sorted Z-values for motif Gata4



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_32276400 11.481 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr11_+_32276893 10.613 ENSMUST00000145569.1
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr3_+_102010138 7.145 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr4_+_13751297 5.680 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_45311538 4.040 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr3_-_154330543 3.592 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr7_-_99238564 3.325 ENSMUST00000064231.7
Mogat2
monoacylglycerol O-acyltransferase 2
chr17_-_84682932 2.888 ENSMUST00000066175.3
Abcg5
ATP-binding cassette, sub-family G (WHITE), member 5
chr8_+_45628176 2.840 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr8_+_45627709 2.616 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr8_+_45627946 2.585 ENSMUST00000145458.1
Sorbs2
sorbin and SH3 domain containing 2
chr16_-_34263179 2.545 ENSMUST00000114949.1
ENSMUST00000114954.1
Kalrn

kalirin, RhoGEF kinase

chrX_+_150547375 2.434 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr17_+_36869567 2.286 ENSMUST00000060524.9
Trim10
tripartite motif-containing 10
chr16_-_34262830 2.270 ENSMUST00000114947.1
Kalrn
kalirin, RhoGEF kinase
chr16_-_34262945 2.164 ENSMUST00000114953.1
Kalrn
kalirin, RhoGEF kinase
chr4_-_46404224 2.095 ENSMUST00000107764.2
Hemgn
hemogen
chr1_+_12718496 2.045 ENSMUST00000088585.3
Sulf1
sulfatase 1
chr2_+_103957976 1.982 ENSMUST00000156813.1
ENSMUST00000170926.1
Lmo2

LIM domain only 2

chr15_-_83170168 1.981 ENSMUST00000162834.1
Cyb5r3
cytochrome b5 reductase 3
chr7_-_98112618 1.951 ENSMUST00000153657.1
Myo7a
myosin VIIA
chr1_-_56969864 1.943 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr3_+_89136133 1.939 ENSMUST00000047111.6
Pklr
pyruvate kinase liver and red blood cell
chr5_-_24329556 1.897 ENSMUST00000115098.2
Kcnh2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr3_+_96596628 1.864 ENSMUST00000058943.7
Ankrd34a
ankyrin repeat domain 34A
chr1_-_56969827 1.788 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr2_+_65845833 1.758 ENSMUST00000053910.3
Csrnp3
cysteine-serine-rich nuclear protein 3
chr1_-_132367879 1.743 ENSMUST00000142609.1
Tmcc2
transmembrane and coiled-coil domains 2
chr8_+_45658273 1.733 ENSMUST00000153798.1
Sorbs2
sorbin and SH3 domain containing 2
chr15_-_83170498 1.731 ENSMUST00000162178.1
Cyb5r3
cytochrome b5 reductase 3
chr5_-_73191848 1.665 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr2_-_153241402 1.607 ENSMUST00000056924.7
Plagl2
pleiomorphic adenoma gene-like 2
chr4_-_87806296 1.481 ENSMUST00000126353.1
ENSMUST00000149357.1
Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr8_+_45658666 1.443 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr11_+_5009515 1.412 ENSMUST00000101613.2
Ap1b1
adaptor protein complex AP-1, beta 1 subunit
chr4_-_87806276 1.390 ENSMUST00000148059.1
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr15_-_77153772 1.335 ENSMUST00000166610.1
ENSMUST00000111581.2
Rbfox2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr9_+_44379536 1.316 ENSMUST00000161318.1
ENSMUST00000160902.1
Hyou1

hypoxia up-regulated 1

chr19_-_43524462 1.309 ENSMUST00000026196.7
Got1
glutamate oxaloacetate transaminase 1, soluble
chr9_+_44379490 1.245 ENSMUST00000066601.6
Hyou1
hypoxia up-regulated 1
chr3_+_90080442 1.206 ENSMUST00000127955.1
Tpm3
tropomyosin 3, gamma
chr16_-_46010212 1.204 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr5_-_123666682 1.174 ENSMUST00000149410.1
Clip1
CAP-GLY domain containing linker protein 1
chr16_-_63864114 1.166 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr2_+_65845767 1.166 ENSMUST00000122912.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr10_+_80019621 1.151 ENSMUST00000043311.6
Hmha1
histocompatibility (minor) HA-1
chr10_+_61648552 1.119 ENSMUST00000020286.6
Ppa1
pyrophosphatase (inorganic) 1
chr19_-_7295394 1.104 ENSMUST00000025921.8
Mark2
MAP/microtubule affinity-regulating kinase 2
chr11_-_102469839 1.103 ENSMUST00000103086.3
Itga2b
integrin alpha 2b
chr15_-_103251465 1.052 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
Nfe2




nuclear factor, erythroid derived 2




chr8_+_70072896 1.048 ENSMUST00000110160.2
ENSMUST00000049197.5
Tm6sf2

transmembrane 6 superfamily member 2

chr2_+_4559742 1.040 ENSMUST00000176828.1
Frmd4a
FERM domain containing 4A
chr6_+_56017489 1.020 ENSMUST00000052827.4
Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr2_+_14873656 1.001 ENSMUST00000114718.1
ENSMUST00000114719.1
Cacnb2

calcium channel, voltage-dependent, beta 2 subunit

chr6_-_115675871 0.982 ENSMUST00000112949.1
Raf1
v-raf-leukemia viral oncogene 1
chr12_-_10900296 0.966 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr7_-_4630473 0.960 ENSMUST00000055085.6
Tmem86b
transmembrane protein 86B
chr10_-_62342674 0.955 ENSMUST00000143179.1
ENSMUST00000130422.1
Hk1

hexokinase 1

chr18_-_61707583 0.913 ENSMUST00000025472.1
Pcyox1l
prenylcysteine oxidase 1 like
chr6_-_124768330 0.905 ENSMUST00000135626.1
Eno2
enolase 2, gamma neuronal
chr11_+_4986824 0.902 ENSMUST00000009234.9
ENSMUST00000109897.1
Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr10_+_53337686 0.896 ENSMUST00000046221.6
ENSMUST00000163319.1
Pln

phospholamban

chr2_-_59948155 0.861 ENSMUST00000153136.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr16_+_13358375 0.851 ENSMUST00000149359.1
Mkl2
MKL/myocardin-like 2
chr7_+_43634718 0.822 ENSMUST00000032663.8
Ceacam18
carcinoembryonic antigen-related cell adhesion molecule 18
chr11_+_101260569 0.809 ENSMUST00000103108.1
Wnk4
WNK lysine deficient protein kinase 4
chr13_-_91388079 0.796 ENSMUST00000181054.1
A830009L08Rik
RIKEN cDNA A830009L08 gene
chr2_-_121037048 0.788 ENSMUST00000102490.3
Epb4.2
erythrocyte protein band 4.2
chr16_-_16560046 0.777 ENSMUST00000172181.2
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr9_-_106887000 0.762 ENSMUST00000055843.7
Rbm15b
RNA binding motif protein 15B
chr1_+_180851131 0.757 ENSMUST00000038091.6
Sde2
SDE2 telomere maintenance homolog (S. pombe)
chr2_-_26246707 0.730 ENSMUST00000166349.1
C030048H21Rik
RIKEN cDNA C030048H21 gene
chr15_+_60822947 0.725 ENSMUST00000180730.1
9930014A18Rik
RIKEN cDNA 9930014A18 gene
chr17_+_57249450 0.720 ENSMUST00000019631.9
Trip10
thyroid hormone receptor interactor 10
chr9_-_44342332 0.717 ENSMUST00000097558.3
Hmbs
hydroxymethylbilane synthase
chr10_-_19011948 0.708 ENSMUST00000105527.1
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr7_+_119900099 0.697 ENSMUST00000106516.1
Lyrm1
LYR motif containing 1
chr8_-_122699066 0.677 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr19_+_24875679 0.654 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr6_-_127109517 0.641 ENSMUST00000039913.8
9630033F20Rik
RIKEN cDNA 9630033F20 gene
chr3_-_63851251 0.634 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1


phospholipase C, eta 1


chr9_+_66350465 0.621 ENSMUST00000042824.6
Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chrX_+_93675088 0.607 ENSMUST00000045898.3
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chrX_+_169685191 0.604 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr9_-_77251871 0.599 ENSMUST00000183955.1
Mlip
muscular LMNA-interacting protein
chr11_+_73047783 0.585 ENSMUST00000021135.3
1200014J11Rik
RIKEN cDNA 1200014J11 gene
chr9_-_77251829 0.581 ENSMUST00000184322.1
ENSMUST00000184316.1
Mlip

muscular LMNA-interacting protein

chr10_-_80421847 0.569 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr1_+_135818593 0.537 ENSMUST00000038760.8
Lad1
ladinin
chr6_+_30541582 0.535 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr3_-_88577208 0.511 ENSMUST00000098952.2
Gm10704
predicted pseudogene 10704
chr11_+_88047788 0.481 ENSMUST00000107920.3
Srsf1
serine/arginine-rich splicing factor 1
chr8_+_4325205 0.475 ENSMUST00000127460.1
ENSMUST00000136191.1
ENSMUST00000069762.9
ENSMUST00000098949.4
Ccl25

Ccl25

chemokine (C-C motif) ligand 25

chemokine (C-C motif) ligand 25

chr10_-_26078987 0.472 ENSMUST00000066049.6
Tmem200a
transmembrane protein 200A
chrX_+_112311334 0.460 ENSMUST00000026599.3
ENSMUST00000113415.1
Apool

apolipoprotein O-like

chr13_-_18031616 0.445 ENSMUST00000099736.2
Vdac3-ps1
voltage-dependent anion channel 3, pseudogene 1
chr17_-_28915314 0.430 ENSMUST00000062357.4
4930539E08Rik
RIKEN cDNA 4930539E08 gene
chr13_+_42681513 0.426 ENSMUST00000149235.1
Phactr1
phosphatase and actin regulator 1
chr18_+_36952621 0.422 ENSMUST00000115661.2
Pcdha2
protocadherin alpha 2
chr10_+_39133981 0.422 ENSMUST00000019991.7
Tube1
epsilon-tubulin 1
chr17_+_43389436 0.419 ENSMUST00000113599.1
Gpr116
G protein-coupled receptor 116
chr4_-_14621669 0.413 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr3_-_84479418 0.401 ENSMUST00000091002.1
Fhdc1
FH2 domain containing 1
chr3_-_129755305 0.395 ENSMUST00000029653.2
Egf
epidermal growth factor
chr1_-_4496363 0.362 ENSMUST00000116652.2
Sox17
SRY-box containing gene 17
chr2_+_131133497 0.356 ENSMUST00000110225.1
Gm11037
predicted gene 11037
chr1_-_4496400 0.354 ENSMUST00000027035.3
Sox17
SRY-box containing gene 17
chrX_-_7572843 0.343 ENSMUST00000132788.1
Ppp1r3f
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr3_+_84593547 0.336 ENSMUST00000062623.3
Tigd4
tigger transposable element derived 4
chr2_+_84980458 0.306 ENSMUST00000028467.5
Prg2
proteoglycan 2, bone marrow
chr1_-_179803625 0.304 ENSMUST00000027768.7
Ahctf1
AT hook containing transcription factor 1
chr8_-_4325096 0.302 ENSMUST00000098950.4
Elavl1
ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)
chr2_-_33086366 0.282 ENSMUST00000049618.2
Garnl3
GTPase activating RANGAP domain-like 3
chr2_-_33087169 0.282 ENSMUST00000102810.3
Garnl3
GTPase activating RANGAP domain-like 3
chr16_+_58670208 0.281 ENSMUST00000060077.5
Cpox
coproporphyrinogen oxidase
chr11_+_88047302 0.277 ENSMUST00000139129.2
Srsf1
serine/arginine-rich splicing factor 1
chr8_-_46211284 0.274 ENSMUST00000034049.4
Slc25a4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chrX_+_7579666 0.270 ENSMUST00000115740.1
ENSMUST00000115739.1
Foxp3

forkhead box P3

chr15_+_76904070 0.259 ENSMUST00000004072.8
Rpl8
ribosomal protein L8
chr6_-_122856151 0.258 ENSMUST00000042081.8
C3ar1
complement component 3a receptor 1
chr17_+_71204647 0.252 ENSMUST00000126681.1
Lpin2
lipin 2
chr10_-_80433615 0.250 ENSMUST00000105346.3
ENSMUST00000020377.6
ENSMUST00000105340.1
ENSMUST00000020379.6
ENSMUST00000105344.1
ENSMUST00000105342.1
ENSMUST00000105345.3
ENSMUST00000105343.1
Tcf3







transcription factor 3







chr11_+_88047693 0.239 ENSMUST00000079866.4
Srsf1
serine/arginine-rich splicing factor 1
chr17_-_45593626 0.232 ENSMUST00000163905.1
ENSMUST00000167692.1
Slc29a1

solute carrier family 29 (nucleoside transporters), member 1

chr5_+_124483458 0.218 ENSMUST00000111453.1
Snrnp35
small nuclear ribonucleoprotein 35 (U11/U12)
chr14_+_55560904 0.202 ENSMUST00000072530.4
ENSMUST00000128490.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr14_+_75455957 0.200 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chr7_-_44892358 0.174 ENSMUST00000003049.6
Med25
mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)
chr12_-_91746020 0.174 ENSMUST00000166967.1
Ston2
stonin 2
chr3_+_133338936 0.173 ENSMUST00000150386.1
ENSMUST00000125858.1
Ppa2

pyrophosphatase (inorganic) 2

chr4_-_43558386 0.161 ENSMUST00000130353.1
Tln1
talin 1
chr13_+_42709482 0.155 ENSMUST00000066928.5
ENSMUST00000148891.1
Phactr1

phosphatase and actin regulator 1

chr16_+_44943737 0.153 ENSMUST00000114622.3
ENSMUST00000166731.1
Cd200r3

CD200 receptor 3

chr8_-_18741542 0.145 ENSMUST00000033846.6
Angpt2
angiopoietin 2
chr14_+_55561060 0.144 ENSMUST00000117701.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr9_-_21963568 0.142 ENSMUST00000006397.5
Epor
erythropoietin receptor
chr6_-_122609964 0.119 ENSMUST00000032211.4
Gdf3
growth differentiation factor 3
chr1_+_151344472 0.097 ENSMUST00000023918.6
ENSMUST00000097543.1
ENSMUST00000111887.3
Ivns1abp


influenza virus NS1A binding protein


chr4_+_124802543 0.078 ENSMUST00000138807.1
ENSMUST00000030723.2
ENSMUST00000175875.1
Mtf1


metal response element binding transcription factor 1


chr16_-_23520579 0.073 ENSMUST00000089883.5
Masp1
mannan-binding lectin serine peptidase 1
chr5_-_121836852 0.048 ENSMUST00000086310.1
Sh2b3
SH2B adaptor protein 3
chr4_+_102760294 0.000 ENSMUST00000072481.5
ENSMUST00000156596.1
ENSMUST00000080728.6
ENSMUST00000106882.2
Sgip1



SH3-domain GRB2-like (endophilin) interacting protein 1




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 22.1 GO:0015671 oxygen transport(GO:0015671)
1.0 2.9 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
0.9 7.0 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.8 4.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.6 1.9 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.5 4.6 GO:0006071 glycerol metabolic process(GO:0006071)
0.5 2.0 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.4 1.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.3 11.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.3 1.0 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.3 1.0 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.3 1.9 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.3 0.9 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.3 1.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.3 2.9 GO:0007379 segment specification(GO:0007379)
0.3 0.8 GO:0003096 renal sodium ion transport(GO:0003096)
0.3 1.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.2 0.7 GO:0060214 stem cell fate specification(GO:0048866) endocardium formation(GO:0060214) cardiac cell fate determination(GO:0060913) regulation of cardiac cell fate specification(GO:2000043)
0.2 7.1 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.2 0.7 GO:0070428 granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.2 3.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 2.0 GO:0050957 equilibrioception(GO:0050957)
0.2 1.0 GO:0010359 regulation of anion channel activity(GO:0010359)
0.2 1.4 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.2 2.4 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.2 1.7 GO:0090527 actin filament reorganization(GO:0090527)
0.2 2.0 GO:0097067 negative regulation of erythrocyte differentiation(GO:0045647) cellular response to thyroid hormone stimulus(GO:0097067)
0.1 2.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.8 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.7 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.3 GO:0032829 tolerance induction to self antigen(GO:0002513) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.1 1.0 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.5 GO:1904995 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.1 1.0 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 2.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.1 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.1 5.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.9 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.1 1.6 GO:0034377 plasma lipoprotein particle assembly(GO:0034377)
0.1 0.8 GO:0030035 microspike assembly(GO:0030035)
0.1 0.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 1.2 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1 0.7 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.1 0.4 GO:0007262 STAT protein import into nucleus(GO:0007262) negative regulation of cholesterol efflux(GO:0090370) positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.1 0.7 GO:0018065 protein-cofactor linkage(GO:0018065)
0.1 3.7 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 3.6 GO:0021884 forebrain neuron development(GO:0021884)
0.1 0.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.2 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.3 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 2.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.6 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 1.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.3 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 1.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.8 GO:0035886 vascular smooth muscle cell differentiation(GO:0035886)
0.0 1.0 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.0 0.3 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 1.7 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.0 1.1 GO:0002687 positive regulation of leukocyte migration(GO:0002687)
0.0 0.2 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.9 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 22.1 GO:0005833 hemoglobin complex(GO:0005833)
0.6 3.6 GO:0001674 female germ cell nucleus(GO:0001674)
0.3 2.0 GO:0002139 stereocilia coupling link(GO:0002139)
0.3 4.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 2.9 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)
0.2 2.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 1.1 GO:0097427 microtubule bundle(GO:0097427)
0.2 0.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 1.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 1.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.0 GO:0031143 pseudopodium(GO:0031143)
0.1 2.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 6.0 GO:0016363 nuclear matrix(GO:0016363)
0.1 2.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 1.0 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.5 GO:0061617 MICOS complex(GO:0061617)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.0 11.5 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.6 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 1.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 2.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.2 GO:0016605 PML body(GO:0016605)
0.0 1.8 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.3 GO:0043679 axon terminus(GO:0043679)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 4.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.8 GO:0030175 filopodium(GO:0030175)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 22.1 GO:0005344 oxygen transporter activity(GO:0005344)
1.1 3.3 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.6 1.9 GO:0004743 pyruvate kinase activity(GO:0004743)
0.6 1.9 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.4 1.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.4 3.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.4 2.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 0.9 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.3 4.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 1.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.2 1.1 GO:0070051 fibrinogen binding(GO:0070051)
0.2 2.9 GO:0017127 cholesterol transporter activity(GO:0017127)
0.2 1.0 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.2 1.0 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 2.4 GO:0016594 glycine binding(GO:0016594)
0.1 1.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 9.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.0 GO:0016803 ether hydrolase activity(GO:0016803)
0.1 0.8 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 2.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.7 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.5 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 0.9 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 1.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.8 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.3 GO:0004942 anaphylatoxin receptor activity(GO:0004942)
0.1 0.3 GO:2001069 glycogen binding(GO:2001069)
0.1 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 7.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.6 GO:0050733 RS domain binding(GO:0050733)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.6 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 2.0 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 7.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.0 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 2.3 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)