Motif ID: Gata4
Z-value: 0.894
Transcription factors associated with Gata4:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Gata4 | ENSMUSG00000021944.9 | Gata4 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.4 | 22.1 | GO:0015671 | oxygen transport(GO:0015671) |
1.0 | 2.9 | GO:0030300 | regulation of intestinal cholesterol absorption(GO:0030300) |
0.9 | 7.0 | GO:0061368 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
0.8 | 4.0 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
0.6 | 1.9 | GO:0097623 | potassium ion export across plasma membrane(GO:0097623) |
0.5 | 4.6 | GO:0006071 | glycerol metabolic process(GO:0006071) |
0.5 | 2.0 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.4 | 1.2 | GO:0097155 | fasciculation of sensory neuron axon(GO:0097155) |
0.3 | 11.5 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.3 | 1.0 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
0.3 | 1.0 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
0.3 | 1.9 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
0.3 | 0.9 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
0.3 | 1.2 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
0.3 | 2.9 | GO:0007379 | segment specification(GO:0007379) |
0.3 | 0.8 | GO:0003096 | renal sodium ion transport(GO:0003096) |
0.3 | 1.3 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
0.2 | 0.7 | GO:0060214 | stem cell fate specification(GO:0048866) endocardium formation(GO:0060214) cardiac cell fate determination(GO:0060913) regulation of cardiac cell fate specification(GO:2000043) |
0.2 | 7.1 | GO:0007617 | mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705) |
0.2 | 0.7 | GO:0070428 | granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) |
0.2 | 3.7 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.2 | 2.0 | GO:0050957 | equilibrioception(GO:0050957) |
0.2 | 1.0 | GO:0010359 | regulation of anion channel activity(GO:0010359) |
0.2 | 1.4 | GO:1903298 | regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298) |
0.2 | 2.4 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
0.2 | 1.7 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.2 | 2.0 | GO:0097067 | negative regulation of erythrocyte differentiation(GO:0045647) cellular response to thyroid hormone stimulus(GO:0097067) |
0.1 | 2.3 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
0.1 | 0.8 | GO:0002326 | B cell lineage commitment(GO:0002326) |
0.1 | 0.7 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
0.1 | 0.3 | GO:0032829 | tolerance induction to self antigen(GO:0002513) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) |
0.1 | 1.0 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
0.1 | 0.5 | GO:1904995 | negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995) |
0.1 | 1.0 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
0.1 | 2.3 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.1 | 1.1 | GO:0034242 | negative regulation of syncytium formation by plasma membrane fusion(GO:0034242) |
0.1 | 5.7 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
0.1 | 0.9 | GO:0086023 | adrenergic receptor signaling pathway involved in heart process(GO:0086023) |
0.1 | 1.6 | GO:0034377 | plasma lipoprotein particle assembly(GO:0034377) |
0.1 | 0.8 | GO:0030035 | microspike assembly(GO:0030035) |
0.1 | 0.3 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
0.1 | 1.2 | GO:0010614 | negative regulation of cardiac muscle hypertrophy(GO:0010614) |
0.1 | 0.7 | GO:0042538 | hyperosmotic salinity response(GO:0042538) |
0.1 | 0.4 | GO:0007262 | STAT protein import into nucleus(GO:0007262) negative regulation of cholesterol efflux(GO:0090370) positive regulation of hyaluronan biosynthetic process(GO:1900127) |
0.1 | 0.7 | GO:0018065 | protein-cofactor linkage(GO:0018065) |
0.1 | 3.7 | GO:1902653 | cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653) |
0.1 | 3.6 | GO:0021884 | forebrain neuron development(GO:0021884) |
0.1 | 0.1 | GO:0048859 | formation of anatomical boundary(GO:0048859) |
0.0 | 0.2 | GO:1903215 | negative regulation of protein targeting to mitochondrion(GO:1903215) |
0.0 | 0.1 | GO:0048014 | Tie signaling pathway(GO:0048014) |
0.0 | 0.3 | GO:0032693 | negative regulation of interleukin-10 production(GO:0032693) |
0.0 | 2.9 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.0 | 0.6 | GO:0021702 | cerebellar Purkinje cell differentiation(GO:0021702) |
0.0 | 0.1 | GO:0060979 | vasculogenesis involved in coronary vascular morphogenesis(GO:0060979) |
0.0 | 0.1 | GO:0046501 | protoporphyrinogen IX metabolic process(GO:0046501) |
0.0 | 0.2 | GO:0015862 | uridine transport(GO:0015862) |
0.0 | 1.0 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.0 | 0.3 | GO:2000465 | regulation of glycogen (starch) synthase activity(GO:2000465) |
0.0 | 0.5 | GO:0042407 | cristae formation(GO:0042407) |
0.0 | 1.1 | GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) |
0.0 | 0.8 | GO:0035886 | vascular smooth muscle cell differentiation(GO:0035886) |
0.0 | 1.0 | GO:0010921 | regulation of phosphatase activity(GO:0010921) |
0.0 | 0.3 | GO:0051292 | nuclear pore complex assembly(GO:0051292) |
0.0 | 0.2 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
0.0 | 0.3 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.0 | 0.8 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
0.0 | 0.6 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
0.0 | 1.7 | GO:0045667 | regulation of osteoblast differentiation(GO:0045667) |
0.0 | 1.1 | GO:0002687 | positive regulation of leukocyte migration(GO:0002687) |
0.0 | 0.2 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
0.0 | 0.9 | GO:0006096 | glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757) |
0.0 | 0.1 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.8 | 22.1 | GO:0005833 | hemoglobin complex(GO:0005833) |
0.6 | 3.6 | GO:0001674 | female germ cell nucleus(GO:0001674) |
0.3 | 2.0 | GO:0002139 | stereocilia coupling link(GO:0002139) |
0.3 | 4.0 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.3 | 2.9 | GO:0098533 | ATPase dependent transmembrane transport complex(GO:0098533) |
0.2 | 2.6 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.2 | 1.1 | GO:0097427 | microtubule bundle(GO:0097427) |
0.2 | 0.9 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.2 | 1.0 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
0.1 | 1.2 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
0.1 | 1.0 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.1 | 1.0 | GO:0031143 | pseudopodium(GO:0031143) |
0.1 | 2.9 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.1 | 6.0 | GO:0016363 | nuclear matrix(GO:0016363) |
0.1 | 2.3 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.1 | 1.0 | GO:0097228 | sperm principal piece(GO:0097228) |
0.1 | 0.9 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.1 | 0.5 | GO:0061617 | MICOS complex(GO:0061617) |
0.0 | 1.2 | GO:0002102 | podosome(GO:0002102) |
0.0 | 11.5 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
0.0 | 0.6 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 1.0 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.0 | 1.9 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 0.8 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.0 | 0.2 | GO:0000243 | commitment complex(GO:0000243) |
0.0 | 2.8 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
0.0 | 0.6 | GO:0045171 | intercellular bridge(GO:0045171) |
0.0 | 1.2 | GO:0016605 | PML body(GO:0016605) |
0.0 | 1.8 | GO:0005923 | bicellular tight junction(GO:0005923) |
0.0 | 1.3 | GO:0043679 | axon terminus(GO:0043679) |
0.0 | 0.3 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.0 | 4.2 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 2.4 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.0 | 0.8 | GO:0030175 | filopodium(GO:0030175) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.4 | 22.1 | GO:0005344 | oxygen transporter activity(GO:0005344) |
1.1 | 3.3 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
0.6 | 1.9 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
0.6 | 1.9 | GO:1902282 | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282) |
0.4 | 1.3 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) |
0.4 | 3.7 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
0.4 | 2.0 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.3 | 0.9 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
0.3 | 4.0 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.3 | 1.3 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
0.2 | 1.1 | GO:0070051 | fibrinogen binding(GO:0070051) |
0.2 | 2.9 | GO:0017127 | cholesterol transporter activity(GO:0017127) |
0.2 | 1.0 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
0.2 | 1.0 | GO:0008865 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
0.2 | 2.4 | GO:0016594 | glycine binding(GO:0016594) |
0.1 | 1.2 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
0.1 | 9.1 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.1 | 1.0 | GO:0016803 | ether hydrolase activity(GO:0016803) |
0.1 | 0.8 | GO:0070644 | vitamin D response element binding(GO:0070644) |
0.1 | 2.0 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.1 | 0.7 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
0.1 | 0.5 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
0.1 | 0.9 | GO:0016670 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) |
0.1 | 1.0 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.1 | 0.8 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
0.1 | 0.9 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.1 | 0.5 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
0.1 | 0.3 | GO:0004942 | anaphylatoxin receptor activity(GO:0004942) |
0.1 | 0.3 | GO:2001069 | glycogen binding(GO:2001069) |
0.1 | 0.3 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
0.1 | 1.2 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.1 | 7.8 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.1 | 1.1 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.1 | 0.6 | GO:0050733 | RS domain binding(GO:0050733) |
0.0 | 0.3 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.0 | 0.6 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
0.0 | 2.0 | GO:0001191 | transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191) |
0.0 | 7.1 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 0.6 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
0.0 | 0.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.0 | 1.0 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
0.0 | 0.7 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
0.0 | 1.1 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 0.2 | GO:0030274 | LIM domain binding(GO:0030274) |
0.0 | 0.3 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
0.0 | 0.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 2.3 | GO:0008565 | protein transporter activity(GO:0008565) |
0.0 | 0.1 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
0.0 | 0.4 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.0 | 0.2 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |