Motif ID: Gata4

Z-value: 0.894


Transcription factors associated with Gata4:

Gene SymbolEntrez IDGene Name
Gata4 ENSMUSG00000021944.9 Gata4



Activity profile for motif Gata4.

activity profile for motif Gata4


Sorted Z-values histogram for motif Gata4

Sorted Z-values for motif Gata4



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata4

PNG image of the network

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Top targets:


Showing 1 to 20 of 142 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_32276400 11.481 ENSMUST00000020531.2
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr11_+_32276893 10.613 ENSMUST00000145569.1
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr3_+_102010138 7.145 ENSMUST00000066187.4
 Nhlh2
nescient helix loop helix 2
chr4_+_13751297 5.680 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_45311538 4.040 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chr3_-_154330543 3.592 ENSMUST00000184966.1
ENSMUST00000177846.2
 Lhx8

LIM homeobox protein 8

chr7_-_99238564 3.325 ENSMUST00000064231.7
 Mogat2
monoacylglycerol O-acyltransferase 2
chr17_-_84682932 2.888 ENSMUST00000066175.3
 Abcg5
ATP-binding cassette, sub-family G (WHITE), member 5
chr8_+_45628176 2.840 ENSMUST00000130850.1
 Sorbs2
sorbin and SH3 domain containing 2
chr8_+_45627709 2.616 ENSMUST00000134321.1
ENSMUST00000135336.1
 Sorbs2

sorbin and SH3 domain containing 2

chr8_+_45627946 2.585 ENSMUST00000145458.1
 Sorbs2
sorbin and SH3 domain containing 2
chr16_-_34263179 2.545 ENSMUST00000114949.1
ENSMUST00000114954.1
 Kalrn

kalirin, RhoGEF kinase

chrX_+_150547375 2.434 ENSMUST00000066337.6
ENSMUST00000112715.1
 Alas2

aminolevulinic acid synthase 2, erythroid

chr17_+_36869567 2.286 ENSMUST00000060524.9
 Trim10
tripartite motif-containing 10
chr16_-_34262830 2.270 ENSMUST00000114947.1
 Kalrn
kalirin, RhoGEF kinase
chr16_-_34262945 2.164 ENSMUST00000114953.1
 Kalrn
kalirin, RhoGEF kinase
chr4_-_46404224 2.095 ENSMUST00000107764.2
 Hemgn
hemogen
chr1_+_12718496 2.045 ENSMUST00000088585.3
 Sulf1
sulfatase 1
chr2_+_103957976 1.982 ENSMUST00000156813.1
ENSMUST00000170926.1
 Lmo2

LIM domain only 2

chr15_-_83170168 1.981 ENSMUST00000162834.1
 Cyb5r3
cytochrome b5 reductase 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 72 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.4 22.1 GO:0015671 oxygen transport(GO:0015671)
0.3 11.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 7.1 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.9 7.0 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 5.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.5 4.6 GO:0006071 glycerol metabolic process(GO:0006071)
0.8 4.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 3.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 3.7 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 3.6 GO:0021884 forebrain neuron development(GO:0021884)
1.0 2.9 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
0.3 2.9 GO:0007379 segment specification(GO:0007379)
0.0 2.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 2.4 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 2.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 2.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.5 2.0 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 2.0 GO:0050957 equilibrioception(GO:0050957)
0.2 2.0 GO:0097067 negative regulation of erythrocyte differentiation(GO:0045647) cellular response to thyroid hormone stimulus(GO:0097067)
0.6 1.9 GO:0097623 potassium ion export across plasma membrane(GO:0097623)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.8 22.1 GO:0005833 hemoglobin complex(GO:0005833)
0.0 11.5 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 6.0 GO:0016363 nuclear matrix(GO:0016363)
0.0 4.2 GO:0005667 transcription factor complex(GO:0005667)
0.3 4.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.6 3.6 GO:0001674 female germ cell nucleus(GO:0001674)
0.3 2.9 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)
0.1 2.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 2.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.2 2.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 2.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 2.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.3 2.0 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 1.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.8 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.3 GO:0043679 axon terminus(GO:0043679)
0.1 1.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.0 1.2 GO:0016605 PML body(GO:0016605)
0.2 1.1 GO:0097427 microtubule bundle(GO:0097427)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.4 22.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 9.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 7.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 7.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.3 4.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.4 3.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
1.1 3.3 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.2 2.9 GO:0017127 cholesterol transporter activity(GO:0017127)
0.2 2.4 GO:0016594 glycine binding(GO:0016594)
0.0 2.3 GO:0008565 protein transporter activity(GO:0008565)
0.4 2.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 2.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 2.0 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.6 1.9 GO:0004743 pyruvate kinase activity(GO:0004743)
0.6 1.9 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.4 1.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.3 1.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 1.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 1.1 GO:0070051 fibrinogen binding(GO:0070051)