Motif ID: Gata6

Z-value: 0.380


Transcription factors associated with Gata6:

Gene SymbolEntrez IDGene Name
Gata6 ENSMUSG00000005836.8 Gata6



Activity profile for motif Gata6.

activity profile for motif Gata6


Sorted Z-values histogram for motif Gata6

Sorted Z-values for motif Gata6



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_154330543 2.244 ENSMUST00000184966.1
ENSMUST00000177846.2
 Lhx8

LIM homeobox protein 8

chr7_-_103853199 1.955 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr6_-_23248264 1.403 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr11_-_102365111 1.168 ENSMUST00000006749.9
 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr1_+_45311538 0.986 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chr4_-_46404224 0.750 ENSMUST00000107764.2
 Hemgn
hemogen
chr7_-_139582790 0.587 ENSMUST00000106095.2
 Nkx6-2
NK6 homeobox 2
chr7_-_99238564 0.534 ENSMUST00000064231.7
 Mogat2
monoacylglycerol O-acyltransferase 2
chr10_-_86732409 0.516 ENSMUST00000070435.4
 Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr2_+_65930117 0.491 ENSMUST00000176109.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr10_-_62342674 0.401 ENSMUST00000143179.1
ENSMUST00000130422.1
 Hk1

hexokinase 1

chr6_+_86078070 0.392 ENSMUST00000032069.5
 Add2
adducin 2 (beta)
chr5_+_121777929 0.348 ENSMUST00000160821.1
 Atxn2
ataxin 2
chr4_+_13751297 0.346 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_-_65827544 0.332 ENSMUST00000159109.1
 Zfp609
zinc finger protein 609
chr10_-_34207551 0.300 ENSMUST00000048010.7
 Dse
dermatan sulfate epimerase
chr16_-_34262945 0.277 ENSMUST00000114953.1
 Kalrn
kalirin, RhoGEF kinase
chr5_-_73191848 0.264 ENSMUST00000176910.1
 Fryl
furry homolog-like (Drosophila)
chr15_-_83170168 0.259 ENSMUST00000162834.1
 Cyb5r3
cytochrome b5 reductase 3
chr15_-_83170498 0.259 ENSMUST00000162178.1
 Cyb5r3
cytochrome b5 reductase 3
chr9_+_66350465 0.227 ENSMUST00000042824.6
 Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr17_+_71204647 0.217 ENSMUST00000126681.1
 Lpin2
lipin 2
chr6_+_58831748 0.205 ENSMUST00000126292.1
ENSMUST00000031823.5
 Herc3

hect domain and RLD 3

chr11_+_4883186 0.203 ENSMUST00000139737.1
 Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr19_+_4711153 0.196 ENSMUST00000008991.6
 Sptbn2
spectrin beta, non-erythrocytic 2
chr2_+_110597298 0.184 ENSMUST00000045972.6
ENSMUST00000111026.2
 Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr8_-_64205970 0.184 ENSMUST00000066166.4
 Tll1
tolloid-like
chr15_-_103251465 0.178 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
 Nfe2




nuclear factor, erythroid derived 2




chr11_+_67586675 0.176 ENSMUST00000108680.1
 Gas7
growth arrest specific 7
chr17_+_57249450 0.173 ENSMUST00000019631.9
 Trip10
thyroid hormone receptor interactor 10
chr2_-_59948155 0.156 ENSMUST00000153136.1
 Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr2_-_33087169 0.147 ENSMUST00000102810.3
 Garnl3
GTPase activating RANGAP domain-like 3
chr7_+_110627650 0.147 ENSMUST00000033054.8
 Adm
adrenomedullin
chr2_+_72476225 0.144 ENSMUST00000157019.1
 Cdca7
cell division cycle associated 7
chr4_+_136143497 0.142 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chr2_+_172370658 0.132 ENSMUST00000151511.1
ENSMUST00000116375.1
 Cstf1

cleavage stimulation factor, 3' pre-RNA, subunit 1

chr9_+_44379490 0.126 ENSMUST00000066601.6
 Hyou1
hypoxia up-regulated 1
chr8_+_45628176 0.122 ENSMUST00000130850.1
 Sorbs2
sorbin and SH3 domain containing 2
chr5_+_76840597 0.120 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
 C530008M17Rik


RIKEN cDNA C530008M17 gene


chr8_+_45627946 0.118 ENSMUST00000145458.1
 Sorbs2
sorbin and SH3 domain containing 2
chr11_-_70220969 0.116 ENSMUST00000060010.2
 Slc16a13
solute carrier family 16 (monocarboxylic acid transporters), member 13
chr2_-_7396192 0.115 ENSMUST00000137733.2
 Celf2
CUGBP, Elav-like family member 2
chr5_-_30461902 0.113 ENSMUST00000133509.1
ENSMUST00000074171.6
ENSMUST00000114747.2
ENSMUST00000144125.1
 Otof



otoferlin



chr17_+_34604819 0.106 ENSMUST00000173242.1
 Agpat1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr9_-_106887000 0.094 ENSMUST00000055843.7
 Rbm15b
RNA binding motif protein 15B
chr11_+_98026918 0.091 ENSMUST00000017548.6
 Rpl19
ribosomal protein L19
chr5_-_111761697 0.090 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
 E130006D01Rik


RIKEN cDNA E130006D01 gene


chr10_+_53337686 0.089 ENSMUST00000046221.6
ENSMUST00000163319.1
 Pln

phospholamban

chr6_-_7983424 0.089 ENSMUST00000178598.1
 Gm9825
predicted gene 9825
chr6_+_58833689 0.088 ENSMUST00000041401.8
 Herc3
hect domain and RLD 3
chr2_-_33086366 0.082 ENSMUST00000049618.2
 Garnl3
GTPase activating RANGAP domain-like 3
chr11_+_98026695 0.074 ENSMUST00000092425.4
 Rpl19
ribosomal protein L19
chr2_-_172370506 0.070 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
 Aurka


aurora kinase A


chr2_-_7395879 0.064 ENSMUST00000182404.1
 Celf2
CUGBP, Elav-like family member 2
chr13_-_91388079 0.060 ENSMUST00000181054.1
 A830009L08Rik
RIKEN cDNA A830009L08 gene
chr2_+_80617045 0.055 ENSMUST00000028384.4
 Dusp19
dual specificity phosphatase 19
chr16_+_58670208 0.041 ENSMUST00000060077.5
 Cpox
coproporphyrinogen oxidase
chr11_+_87581041 0.034 ENSMUST00000018544.5
ENSMUST00000063156.4
ENSMUST00000107960.1
 Sept4


septin 4


chr9_-_44342332 0.030 ENSMUST00000097558.3
 Hmbs
hydroxymethylbilane synthase
chr11_-_53707269 0.028 ENSMUST00000124352.1
ENSMUST00000020649.7
 Rad50

RAD50 homolog (S. cerevisiae)

chr2_+_71786923 0.025 ENSMUST00000112101.1
ENSMUST00000028522.3
 Itga6

integrin alpha 6

chr11_+_4986824 0.025 ENSMUST00000009234.9
ENSMUST00000109897.1
 Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr2_+_72476159 0.018 ENSMUST00000102691.4
 Cdca7
cell division cycle associated 7
chr16_+_36041184 0.017 ENSMUST00000042203.8
 Wdr5b
WD repeat domain 5B
chr11_-_103697898 0.016 ENSMUST00000021329.7
 Gosr2
golgi SNAP receptor complex member 2
chr11_+_95712673 0.010 ENSMUST00000107717.1
 Zfp652
zinc finger protein 652
chr7_-_119895446 0.009 ENSMUST00000098080.2
 Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr10_+_40883469 0.006 ENSMUST00000019975.7
 Wasf1
WAS protein family, member 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0015671 oxygen transport(GO:0015671)
0.2 1.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 1.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.6 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.4 GO:0010359 regulation of anion channel activity(GO:0010359)
0.1 0.5 GO:0046339 glycerol metabolic process(GO:0006071) diacylglycerol metabolic process(GO:0046339)
0.1 1.2 GO:0015701 bicarbonate transport(GO:0015701) response to arsenic-containing substance(GO:0046685)
0.0 2.2 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.3 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.8 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.2 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.0 0.2 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0 0.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056) positive regulation of oocyte development(GO:0060282)
0.0 0.4 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.1 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.3 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 2.0 GO:0005833 hemoglobin complex(GO:0005833)
0.1 1.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.2 GO:0014704 intercalated disc(GO:0014704)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.2 0.5 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 0.4 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.2 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.1 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.5 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)