Motif ID: Gbx1_Nobox_Alx3
Z-value: 0.701
Transcription factors associated with Gbx1_Nobox_Alx3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Alx3 | ENSMUSG00000014603.1 | Alx3 |
| Gbx1 | ENSMUSG00000067724.4 | Gbx1 |
| Nobox | ENSMUSG00000029736.9 | Nobox |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Alx3 | mm10_v2_chr3_+_107595031_107595164 | 0.59 | 3.5e-04 | Click! |
| Gbx1 | mm10_v2_chr5_-_24527276_24527276 | 0.38 | 2.8e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 4.6 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
| 1.1 | 3.2 | GO:0090425 | hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979) |
| 0.8 | 2.5 | GO:0048818 | embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364) |
| 0.7 | 1.3 | GO:0072106 | regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107) |
| 0.7 | 2.0 | GO:0003278 | apoptotic process involved in heart morphogenesis(GO:0003278) regulation of vascular wound healing(GO:0061043) glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144) |
| 0.6 | 1.9 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.6 | 4.6 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.6 | 2.2 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
| 0.5 | 3.1 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.5 | 1.9 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
| 0.4 | 1.3 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
| 0.4 | 7.4 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.4 | 2.1 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.3 | 1.0 | GO:0090271 | positive regulation of fibroblast growth factor production(GO:0090271) |
| 0.3 | 1.4 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) resolution of recombination intermediates(GO:0071139) |
| 0.3 | 1.0 | GO:2000977 | regulation of forebrain neuron differentiation(GO:2000977) |
| 0.3 | 4.3 | GO:0031017 | exocrine pancreas development(GO:0031017) |
| 0.3 | 0.9 | GO:0030862 | neuroblast division in subventricular zone(GO:0021849) regulation of polarized epithelial cell differentiation(GO:0030860) positive regulation of polarized epithelial cell differentiation(GO:0030862) |
| 0.3 | 9.5 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 0.3 | 0.9 | GO:1902608 | testosterone biosynthetic process(GO:0061370) regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608) regulation of testosterone biosynthetic process(GO:2000224) |
| 0.3 | 2.0 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.3 | 0.8 | GO:0003162 | atrioventricular node development(GO:0003162) |
| 0.3 | 1.0 | GO:0035553 | oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553) |
| 0.3 | 0.3 | GO:0032472 | Golgi calcium ion transport(GO:0032472) |
| 0.2 | 0.7 | GO:0008228 | opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
| 0.2 | 1.3 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
| 0.2 | 1.1 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
| 0.2 | 1.2 | GO:0042795 | snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.2 | 0.2 | GO:0009946 | proximal/distal axis specification(GO:0009946) |
| 0.2 | 1.7 | GO:0045602 | negative regulation of endothelial cell differentiation(GO:0045602) |
| 0.2 | 0.7 | GO:0010700 | negative regulation of norepinephrine secretion(GO:0010700) |
| 0.2 | 0.7 | GO:0090324 | negative regulation of oxidative phosphorylation(GO:0090324) |
| 0.2 | 0.5 | GO:0051798 | positive regulation of hair follicle development(GO:0051798) |
| 0.2 | 1.0 | GO:0010624 | regulation of Schwann cell proliferation(GO:0010624) |
| 0.2 | 0.5 | GO:0060166 | olfactory pit development(GO:0060166) |
| 0.2 | 1.5 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.2 | 0.8 | GO:0015692 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
| 0.2 | 2.2 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.2 | 0.6 | GO:0060690 | epithelial cell differentiation involved in salivary gland development(GO:0060690) |
| 0.2 | 1.7 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.2 | 1.2 | GO:0060872 | semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872) |
| 0.2 | 0.6 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
| 0.1 | 0.3 | GO:1904956 | regulation of midbrain dopaminergic neuron differentiation(GO:1904956) |
| 0.1 | 0.5 | GO:0006742 | NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364) |
| 0.1 | 0.4 | GO:0042536 | negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) |
| 0.1 | 1.0 | GO:0097460 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import(GO:0070627) ferrous iron import into cell(GO:0097460) |
| 0.1 | 3.4 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.1 | 2.0 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
| 0.1 | 1.3 | GO:2000671 | regulation of motor neuron apoptotic process(GO:2000671) |
| 0.1 | 0.6 | GO:0021775 | smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776) |
| 0.1 | 2.0 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 0.7 | GO:0007195 | adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) |
| 0.1 | 0.7 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.1 | 0.3 | GO:1900275 | negative regulation of phospholipase C activity(GO:1900275) |
| 0.1 | 1.1 | GO:0044458 | motile cilium assembly(GO:0044458) |
| 0.1 | 0.7 | GO:0050957 | equilibrioception(GO:0050957) |
| 0.1 | 0.4 | GO:0072488 | ammonium transmembrane transport(GO:0072488) |
| 0.1 | 0.9 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.1 | 0.5 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.1 | 2.2 | GO:0006907 | pinocytosis(GO:0006907) |
| 0.1 | 2.8 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.1 | 0.4 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.1 | 2.4 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.1 | 2.3 | GO:0045879 | negative regulation of smoothened signaling pathway(GO:0045879) |
| 0.1 | 0.4 | GO:0002317 | plasma cell differentiation(GO:0002317) |
| 0.1 | 1.0 | GO:0030497 | fatty acid elongation(GO:0030497) |
| 0.1 | 0.1 | GO:0060648 | mammary gland bud morphogenesis(GO:0060648) |
| 0.1 | 0.5 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.1 | 0.9 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 1.0 | GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482) |
| 0.1 | 1.2 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.1 | 0.4 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) |
| 0.1 | 0.3 | GO:0007223 | Wnt signaling pathway, calcium modulating pathway(GO:0007223) |
| 0.1 | 0.1 | GO:0060741 | prostate gland stromal morphogenesis(GO:0060741) alveolar secondary septum development(GO:0061144) |
| 0.1 | 0.7 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.1 | 2.1 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
| 0.1 | 1.1 | GO:0001553 | luteinization(GO:0001553) |
| 0.1 | 1.8 | GO:0046677 | response to antibiotic(GO:0046677) |
| 0.1 | 0.2 | GO:0001543 | ovarian follicle rupture(GO:0001543) |
| 0.1 | 0.8 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.1 | 0.2 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
| 0.1 | 0.5 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.1 | 0.5 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.1 | 0.3 | GO:0034047 | regulation of protein phosphatase type 2A activity(GO:0034047) |
| 0.1 | 0.6 | GO:0019985 | translesion synthesis(GO:0019985) |
| 0.0 | 0.3 | GO:0021756 | striatum development(GO:0021756) |
| 0.0 | 0.4 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.0 | 0.3 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.0 | 0.1 | GO:1900149 | positive regulation of Schwann cell migration(GO:1900149) |
| 0.0 | 0.8 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.0 | 3.2 | GO:0003073 | regulation of systemic arterial blood pressure(GO:0003073) |
| 0.0 | 0.2 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 0.0 | 0.2 | GO:0015867 | ATP transport(GO:0015867) |
| 0.0 | 0.8 | GO:0032291 | central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291) |
| 0.0 | 1.3 | GO:0031365 | N-terminal protein amino acid modification(GO:0031365) |
| 0.0 | 3.9 | GO:0001889 | liver development(GO:0001889) |
| 0.0 | 0.3 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
| 0.0 | 0.4 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.0 | 0.1 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.0 | 0.2 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
| 0.0 | 0.3 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.0 | 1.6 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 0.0 | 0.2 | GO:0032570 | response to progesterone(GO:0032570) |
| 0.0 | 0.6 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) cerebellar Purkinje cell differentiation(GO:0021702) |
| 0.0 | 0.1 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
| 0.0 | 0.5 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.0 | 1.6 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
| 0.0 | 0.1 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
| 0.0 | 0.1 | GO:0010359 | regulation of anion channel activity(GO:0010359) |
| 0.0 | 3.1 | GO:0030178 | negative regulation of Wnt signaling pathway(GO:0030178) |
| 0.0 | 0.6 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.0 | 0.5 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.3 | GO:0046548 | retinal rod cell development(GO:0046548) |
| 0.0 | 0.1 | GO:0036233 | glycine import(GO:0036233) |
| 0.0 | 0.3 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 0.1 | GO:0060527 | prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527) |
| 0.0 | 0.7 | GO:0051693 | actin filament capping(GO:0051693) |
| 0.0 | 0.2 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.0 | 3.4 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.0 | 1.5 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
| 0.0 | 0.2 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 0.0 | 1.5 | GO:0019882 | antigen processing and presentation(GO:0019882) |
| 0.0 | 0.3 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
| 0.0 | 0.3 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.1 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.0 | 0.2 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.0 | 0.1 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.0 | 0.6 | GO:1902593 | protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.7 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.4 | 3.1 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.3 | 5.2 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.3 | 1.4 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.3 | 1.0 | GO:0097450 | astrocyte end-foot(GO:0097450) |
| 0.3 | 1.5 | GO:0001674 | female germ cell nucleus(GO:0001674) |
| 0.2 | 2.7 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.2 | 1.2 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 0.2 | 0.8 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.2 | 0.8 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.1 | 0.7 | GO:0031523 | Myb complex(GO:0031523) |
| 0.1 | 1.4 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.1 | 1.1 | GO:0097433 | dense body(GO:0097433) |
| 0.1 | 4.3 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.1 | 0.7 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.1 | 2.2 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 0.7 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.1 | 3.9 | GO:0016459 | myosin complex(GO:0016459) |
| 0.1 | 0.8 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.1 | 2.1 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 1.1 | GO:0043205 | fibril(GO:0043205) |
| 0.1 | 0.9 | GO:0042555 | MCM complex(GO:0042555) |
| 0.1 | 0.3 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 0.1 | 7.7 | GO:0000792 | heterochromatin(GO:0000792) |
| 0.1 | 1.6 | GO:0043034 | costamere(GO:0043034) |
| 0.1 | 2.5 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 0.2 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.0 | 0.7 | GO:0033655 | host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655) |
| 0.0 | 0.2 | GO:0072487 | MSL complex(GO:0072487) |
| 0.0 | 0.6 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.0 | 2.0 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 0.4 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.0 | 1.2 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 0.2 | GO:0030478 | actin cap(GO:0030478) |
| 0.0 | 0.3 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 1.6 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 0.8 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 1.8 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.2 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.0 | 0.0 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.0 | 3.3 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 0.6 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.0 | 0.3 | GO:0051286 | cell tip(GO:0051286) |
| 0.0 | 0.1 | GO:0060091 | kinocilium(GO:0060091) |
| 0.0 | 0.1 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.0 | 0.2 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 1.3 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 0.2 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.0 | 0.3 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.3 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 0.0 | 0.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 0.2 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 0.0 | 5.6 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 1.0 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.0 | 3.4 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 0.3 | GO:0098644 | complex of collagen trimers(GO:0098644) |
| 0.0 | 0.8 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 0.1 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.0 | 0.6 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 0.9 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.0 | 0.1 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.0 | 0.3 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 4.6 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.5 | 5.1 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 0.5 | 1.5 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.5 | 2.7 | GO:0019865 | immunoglobulin binding(GO:0019865) |
| 0.4 | 3.2 | GO:0050693 | LBD domain binding(GO:0050693) |
| 0.4 | 4.6 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.3 | 1.0 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
| 0.3 | 1.5 | GO:0032027 | myosin light chain binding(GO:0032027) |
| 0.3 | 1.0 | GO:0035515 | oxidative RNA demethylase activity(GO:0035515) |
| 0.3 | 2.0 | GO:0015180 | L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858) |
| 0.2 | 1.4 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
| 0.2 | 0.9 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.2 | 1.1 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
| 0.2 | 1.7 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
| 0.2 | 1.9 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.2 | 2.4 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.2 | 1.1 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.2 | 1.4 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.2 | 7.7 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.2 | 0.8 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
| 0.2 | 1.9 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
| 0.2 | 0.9 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.1 | 0.7 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.1 | 1.0 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 0.1 | 3.9 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.1 | 2.5 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.1 | 0.5 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
| 0.1 | 0.6 | GO:0015265 | urea channel activity(GO:0015265) |
| 0.1 | 1.2 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.1 | 0.9 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.1 | 0.6 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.1 | 0.7 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.1 | 0.3 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.1 | 1.4 | GO:0008545 | JUN kinase kinase activity(GO:0008545) |
| 0.1 | 0.2 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
| 0.1 | 0.6 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 1.1 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 0.1 | 1.3 | GO:0016208 | AMP binding(GO:0016208) |
| 0.1 | 1.1 | GO:0016594 | glycine binding(GO:0016594) |
| 0.1 | 0.5 | GO:0005451 | monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.1 | 3.6 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 0.5 | GO:0048185 | activin binding(GO:0048185) |
| 0.1 | 0.5 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.1 | 0.2 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
| 0.1 | 0.2 | GO:0015217 | ADP transmembrane transporter activity(GO:0015217) coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122) |
| 0.1 | 1.9 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.1 | 0.2 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
| 0.1 | 7.2 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 1.1 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.7 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 0.3 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.0 | 18.3 | GO:0000982 | transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) |
| 0.0 | 0.1 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
| 0.0 | 0.8 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 0.8 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.2 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.0 | 0.1 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 0.5 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.0 | 0.6 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.0 | 0.6 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 1.7 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.0 | 0.3 | GO:1990405 | protein antigen binding(GO:1990405) |
| 0.0 | 0.1 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.0 | 0.8 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.0 | 0.7 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 0.8 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.0 | 0.5 | GO:0004551 | nucleotide diphosphatase activity(GO:0004551) |
| 0.0 | 0.4 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
| 0.0 | 0.5 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.3 | GO:0004889 | acetylcholine-activated cation-selective channel activity(GO:0004889) |
| 0.0 | 0.5 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 5.4 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.0 | 0.9 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.0 | 1.7 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 1.0 | GO:0050694 | galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.0 | 0.4 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 0.6 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 1.5 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 0.6 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.0 | 1.0 | GO:0008528 | G-protein coupled peptide receptor activity(GO:0008528) |
| 0.0 | 0.9 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.0 | 0.7 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 0.5 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 1.6 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.0 | 0.6 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.4 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.2 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.0 | 0.1 | GO:0015288 | porin activity(GO:0015288) |
| 0.0 | 0.3 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.0 | 0.3 | GO:0016661 | oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661) |
| 0.0 | 0.2 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.0 | 0.1 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.0 | 0.1 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.0 | 6.1 | GO:0044212 | transcription regulatory region DNA binding(GO:0044212) |
| 0.0 | 2.8 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.0 | 0.6 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 0.2 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.0 | 0.6 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 0.1 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.0 | 0.1 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.0 | 3.8 | GO:0003779 | actin binding(GO:0003779) |
| 0.0 | 0.4 | GO:0035254 | glutamate receptor binding(GO:0035254) |
| 0.0 | 1.3 | GO:0008276 | protein methyltransferase activity(GO:0008276) |
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