Motif ID: Gcm1

Z-value: 0.469


Transcription factors associated with Gcm1:

Gene SymbolEntrez IDGene Name
Gcm1 ENSMUSG00000023333.7 Gcm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gcm1mm10_v2_chr9_+_78051938_78051958-0.096.0e-01Click!


Activity profile for motif Gcm1.

activity profile for motif Gcm1


Sorted Z-values histogram for motif Gcm1

Sorted Z-values for motif Gcm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gcm1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_6065538 2.364 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr7_+_46396439 1.897 ENSMUST00000025202.6
Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr17_+_8311101 1.029 ENSMUST00000154553.1
Sft2d1
SFT2 domain containing 1
chr1_-_79761752 0.997 ENSMUST00000113512.1
ENSMUST00000113513.1
ENSMUST00000113515.1
ENSMUST00000113514.1
ENSMUST00000113510.1
ENSMUST00000113511.1
ENSMUST00000048820.7
Wdfy1






WD repeat and FYVE domain containing 1






chr14_-_19977249 0.991 ENSMUST00000160013.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr2_+_96318014 0.982 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chr16_-_91597636 0.971 ENSMUST00000023686.8
Tmem50b
transmembrane protein 50B
chr18_-_39487096 0.806 ENSMUST00000097592.2
ENSMUST00000115571.1
Nr3c1

nuclear receptor subfamily 3, group C, member 1

chrX_+_73503074 0.782 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
Atp2b3


ATPase, Ca++ transporting, plasma membrane 3


chr7_-_101011976 0.756 ENSMUST00000178340.1
ENSMUST00000037540.3
P2ry2

purinergic receptor P2Y, G-protein coupled 2

chr9_-_70657121 0.742 ENSMUST00000049031.5
Fam63b
family with sequence similarity 63, member B
chr13_+_8202860 0.729 ENSMUST00000064473.6
Adarb2
adenosine deaminase, RNA-specific, B2
chr11_-_75454656 0.666 ENSMUST00000173320.1
Wdr81
WD repeat domain 81
chr11_-_60352869 0.631 ENSMUST00000095254.5
ENSMUST00000102683.4
ENSMUST00000093048.6
ENSMUST00000093046.6
ENSMUST00000064019.8
ENSMUST00000102682.4
Tom1l2





target of myb1-like 2 (chicken)





chr5_-_110343009 0.623 ENSMUST00000058016.9
ENSMUST00000112478.3
P2rx2

purinergic receptor P2X, ligand-gated ion channel, 2

chr13_-_100108337 0.614 ENSMUST00000180822.1
BC001981
cDNA sequence BC001981
chr11_+_116918844 0.604 ENSMUST00000103027.3
Mgat5b
mannoside acetylglucosaminyltransferase 5, isoenzyme B
chr10_-_76345254 0.604 ENSMUST00000036033.7
ENSMUST00000160048.1
ENSMUST00000105417.3
Dip2a


DIP2 disco-interacting protein 2 homolog A (Drosophila)


chr4_-_136956784 0.577 ENSMUST00000030420.8
Epha8
Eph receptor A8
chr19_+_6400523 0.574 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
Rasgrp2



RAS, guanyl releasing protein 2



chr9_+_70656248 0.491 ENSMUST00000098589.2
Gm10642
predicted gene 10642
chr16_+_36875119 0.487 ENSMUST00000135406.1
ENSMUST00000114812.1
ENSMUST00000134616.1
ENSMUST00000023534.6
Golgb1


Golgb1
golgi autoantigen, golgin subfamily b, macrogolgin 1


golgi autoantigen, golgin subfamily b, macrogolgin 1
chr7_+_4922251 0.452 ENSMUST00000047309.5
Nat14
N-acetyltransferase 14
chr11_+_101246960 0.448 ENSMUST00000107282.3
Ramp2
receptor (calcitonin) activity modifying protein 2
chr8_+_91070052 0.447 ENSMUST00000034091.7
Rbl2
retinoblastoma-like 2
chr17_+_25471564 0.443 ENSMUST00000025002.1
Tekt4
tektin 4
chr3_-_69598822 0.435 ENSMUST00000061826.1
B3galnt1
UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1
chr13_+_8202922 0.433 ENSMUST00000123187.1
Adarb2
adenosine deaminase, RNA-specific, B2
chr7_-_29906524 0.414 ENSMUST00000159920.1
ENSMUST00000162592.1
Zfp27

zinc finger protein 27

chr2_+_169633517 0.393 ENSMUST00000109157.1
Tshz2
teashirt zinc finger family member 2
chr11_-_106613370 0.391 ENSMUST00000128933.1
Tex2
testis expressed gene 2
chr10_-_13868779 0.382 ENSMUST00000105534.3
Aig1
androgen-induced 1
chr7_+_119900099 0.367 ENSMUST00000106516.1
Lyrm1
LYR motif containing 1
chr12_-_119238794 0.361 ENSMUST00000026360.8
Itgb8
integrin beta 8
chr12_+_8674224 0.353 ENSMUST00000111122.2
Pum2
pumilio 2 (Drosophila)
chr5_-_35105691 0.348 ENSMUST00000030986.8
Lrpap1
low density lipoprotein receptor-related protein associated protein 1
chr17_+_24696234 0.336 ENSMUST00000019464.7
Noxo1
NADPH oxidase organizer 1
chr13_+_100107997 0.320 ENSMUST00000142155.1
ENSMUST00000022145.8
ENSMUST00000132053.1
Serf1


small EDRK-rich factor 1


chr19_+_46761578 0.307 ENSMUST00000077666.4
ENSMUST00000099373.4
Cnnm2

cyclin M2

chr17_-_32189457 0.306 ENSMUST00000087721.3
ENSMUST00000162117.1
Ephx3

epoxide hydrolase 3

chr12_+_8674129 0.299 ENSMUST00000111123.2
ENSMUST00000178015.1
ENSMUST00000020915.3
Pum2


pumilio 2 (Drosophila)


chr17_-_32788284 0.270 ENSMUST00000159086.2
Zfp871
zinc finger protein 871
chr13_+_100108155 0.233 ENSMUST00000129014.1
Serf1
small EDRK-rich factor 1
chr7_+_131966446 0.210 ENSMUST00000045840.4
Gpr26
G protein-coupled receptor 26
chr16_-_3907651 0.192 ENSMUST00000177221.1
ENSMUST00000177323.1
1700037C18Rik

RIKEN cDNA 1700037C18 gene

chr14_+_32201937 0.182 ENSMUST00000163350.1
ENSMUST00000170840.1
ENSMUST00000022470.8
ENSMUST00000171279.1
Parg



poly (ADP-ribose) glycohydrolase



chr2_+_48814109 0.176 ENSMUST00000063886.3
Acvr2a
activin receptor IIA
chr6_-_113501818 0.172 ENSMUST00000101059.1
Prrt3
proline-rich transmembrane protein 3
chr15_-_83251720 0.161 ENSMUST00000164614.1
ENSMUST00000049530.6
A4galt

alpha 1,4-galactosyltransferase

chr11_-_98149551 0.160 ENSMUST00000103143.3
Fbxl20
F-box and leucine-rich repeat protein 20
chr13_-_95250166 0.159 ENSMUST00000162153.1
ENSMUST00000160957.2
ENSMUST00000159598.1
ENSMUST00000162412.1
Pde8b



phosphodiesterase 8B



chr11_-_35980473 0.152 ENSMUST00000018993.6
Wwc1
WW, C2 and coiled-coil domain containing 1
chr6_+_6863769 0.150 ENSMUST00000031768.6
Dlx6
distal-less homeobox 6
chr7_-_99182681 0.113 ENSMUST00000033001.4
Dgat2
diacylglycerol O-acyltransferase 2
chr14_+_55578360 0.101 ENSMUST00000174259.1
ENSMUST00000174563.1
ENSMUST00000089619.6
ENSMUST00000172738.1
Psme1



proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)



chr15_-_10470490 0.092 ENSMUST00000136591.1
Dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chrX_+_93286499 0.070 ENSMUST00000046565.7
ENSMUST00000113947.2
Arx

aristaless related homeobox

chr9_+_107580117 0.052 ENSMUST00000093785.4
Nat6
N-acetyltransferase 6
chr10_-_71285234 0.029 ENSMUST00000020085.6
Ube2d1
ubiquitin-conjugating enzyme E2D 1
chr4_-_156234777 0.013 ENSMUST00000105569.3
Klhl17
kelch-like 17
chr16_-_36874806 0.010 ENSMUST00000075946.5
Eaf2
ELL associated factor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
0.2 1.0 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.2 0.8 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 0.7 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 0.7 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 0.8 GO:0060406 positive regulation of penile erection(GO:0060406)
0.1 0.2 GO:0042713 sperm ejaculation(GO:0042713)
0.1 0.3 GO:0010985 negative regulation of lipoprotein particle clearance(GO:0010985)
0.1 0.2 GO:0035106 operant conditioning(GO:0035106)
0.1 0.6 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832)
0.1 0.6 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.4 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 1.9 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.0 0.2 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0098543 detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.4 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 1.0 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.3 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.6 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.5 GO:0071277 cellular response to calcium ion(GO:0071277)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 2.4 GO:0051233 spindle midzone(GO:0051233)
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 1.9 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.2 0.8 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.6 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.3 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 0.6 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) mercury ion binding(GO:0045340)
0.1 2.4 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.6 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.9 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 1.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.4 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 1.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.4 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.5 GO:0034945 dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)