Motif ID: Gcm2

Z-value: 2.201


Transcription factors associated with Gcm2:

Gene SymbolEntrez IDGene Name
Gcm2 ENSMUSG00000021362.6 Gcm2



Activity profile for motif Gcm2.

activity profile for motif Gcm2


Sorted Z-values histogram for motif Gcm2

Sorted Z-values for motif Gcm2



Network of associatons between targets according to the STRING database.



First level regulatory network of Gcm2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_6065737 28.816 ENSMUST00000002817.5
ENSMUST00000109813.2
ENSMUST00000090443.3
 Camk2b


calcium/calmodulin-dependent protein kinase II, beta


chr11_-_6065538 16.991 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
 Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr12_-_79007276 11.642 ENSMUST00000056660.6
ENSMUST00000174721.1
 Tmem229b

transmembrane protein 229B

chrX_-_73880831 11.565 ENSMUST00000102871.3
 L1cam
L1 cell adhesion molecule
chr9_+_112234257 9.163 ENSMUST00000149308.3
ENSMUST00000144424.2
ENSMUST00000139552.2
 2900079G21Rik


RIKEN cDNA 2900079G21 gene


chr2_+_82053222 8.974 ENSMUST00000047527.7
 Zfp804a
zinc finger protein 804A
chr15_-_66831625 8.892 ENSMUST00000164163.1
 Sla
src-like adaptor
chr4_+_13743424 8.871 ENSMUST00000006761.3
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_+_98348404 7.892 ENSMUST00000078694.6
 Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr3_+_96596628 7.295 ENSMUST00000058943.7
 Ankrd34a
ankyrin repeat domain 34A
chr13_-_14523178 7.285 ENSMUST00000110516.2
 Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr5_-_37717122 7.267 ENSMUST00000094836.4
 Stk32b
serine/threonine kinase 32B
chr15_+_25414175 7.094 ENSMUST00000069992.5
 Gm5468
predicted gene 5468
chr6_+_39873271 6.897 ENSMUST00000180886.1
 Tmem178b
transmembrane protein 178B
chr4_+_97777606 6.873 ENSMUST00000075448.6
ENSMUST00000092532.6
 Nfia

nuclear factor I/A

chr11_-_116654245 6.852 ENSMUST00000021166.5
 Cygb
cytoglobin
chr4_+_97777780 6.282 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
 Nfia


nuclear factor I/A


chr9_+_57940104 5.830 ENSMUST00000043059.7
 Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr8_-_70487314 5.712 ENSMUST00000045286.7
 Tmem59l
transmembrane protein 59-like
chr14_-_55116935 5.391 ENSMUST00000022819.5
 Jph4
junctophilin 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 402 entries
Log-likelihood per target Total log-likelihoodTermDescription
15.3 45.8 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
0.5 17.1 GO:0060074 synapse maturation(GO:0060074)
1.2 12.4 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
1.2 9.3 GO:1903423 positive regulation of synaptic vesicle recycling(GO:1903423)
2.6 7.9 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 7.1 GO:1903214 regulation of protein targeting to mitochondrion(GO:1903214)
1.4 6.9 GO:0015671 oxygen transport(GO:0015671)
0.4 6.9 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.3 6.9 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.2 6.8 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.2 6.7 GO:0034605 cellular response to heat(GO:0034605)
0.6 5.8 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 5.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 5.2 GO:0000209 protein polyubiquitination(GO:0000209)
0.5 4.8 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.3 4.6 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.6 4.4 GO:0035902 response to immobilization stress(GO:0035902)
0.4 4.3 GO:0032482 Rab protein signal transduction(GO:0032482)
0.5 4.2 GO:0071420 cellular response to histamine(GO:0071420)
0.3 4.2 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 186 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 43.4 GO:0051233 spindle midzone(GO:0051233)
0.4 17.5 GO:0044295 axonal growth cone(GO:0044295)
0.2 9.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 8.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 7.1 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.2 5.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 5.8 GO:0032839 dendrite cytoplasm(GO:0032839)
1.1 5.4 GO:0030314 junctional membrane complex(GO:0030314)
0.2 5.3 GO:0043194 axon initial segment(GO:0043194)
0.1 5.1 GO:0005776 autophagosome(GO:0005776)
0.1 5.0 GO:0016363 nuclear matrix(GO:0016363)
0.1 4.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 4.4 GO:0043025 neuronal cell body(GO:0043025)
0.2 4.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.4 4.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 4.0 GO:0031225 anchored component of membrane(GO:0031225)
0.4 3.9 GO:0043083 synaptic cleft(GO:0043083)
0.1 3.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 3.7 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 3.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 261 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 47.6 GO:0043274 phospholipase binding(GO:0043274)
2.3 11.6 GO:0033691 sialic acid binding(GO:0033691)
0.0 11.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.3 10.8 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
1.1 9.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
2.6 7.9 GO:0031750 D3 dopamine receptor binding(GO:0031750)
1.5 7.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 7.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 7.1 GO:0008017 microtubule binding(GO:0008017)
1.7 6.9 GO:0004096 catalase activity(GO:0004096)
0.9 6.6 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.6 6.4 GO:0038191 neuropilin binding(GO:0038191)
0.2 6.2 GO:0030215 semaphorin receptor binding(GO:0030215)
1.2 4.9 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.3 4.9 GO:0035497 cAMP response element binding(GO:0035497)
0.5 4.7 GO:0019534 toxin transporter activity(GO:0019534)
0.1 4.4 GO:0035254 glutamate receptor binding(GO:0035254)
0.1 4.3 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.3 4.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
1.3 3.9 GO:0004936 alpha-adrenergic receptor activity(GO:0004936) epinephrine binding(GO:0051379)