Motif ID: Gfi1_Gfi1b

Z-value: 1.229

Transcription factors associated with Gfi1_Gfi1b:

Gene SymbolEntrez IDGene Name
Gfi1 ENSMUSG00000029275.11 Gfi1
Gfi1b ENSMUSG00000026815.8 Gfi1b






Network of associatons between targets according to the STRING database.



First level regulatory network of Gfi1_Gfi1b

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 16.989 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr16_-_26989974 10.621 ENSMUST00000089832.4
Gmnc
geminin coiled-coil domain containing
chr7_+_62376979 5.175 ENSMUST00000080403.5
Magel2
melanoma antigen, family L, 2
chr9_+_3005125 4.959 ENSMUST00000179881.1
Gm11168
predicted gene 11168
chr9_+_3000922 4.879 ENSMUST00000151376.2
Gm10722
predicted gene 10722
chr9_+_3027439 4.480 ENSMUST00000177875.1
ENSMUST00000179982.1
Gm10717

predicted gene 10717

chr9_+_3013140 4.360 ENSMUST00000143083.2
Gm10721
predicted gene 10721
chr9_+_3034599 4.333 ENSMUST00000178641.1
Gm17535
predicted gene, 17535
chr13_+_35659856 4.308 ENSMUST00000075220.6
Cdyl
chromodomain protein, Y chromosome-like
chr3_-_154330543 4.178 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr9_+_3015654 4.023 ENSMUST00000099050.3
Gm10720
predicted gene 10720
chr9_+_3023547 3.875 ENSMUST00000099046.3
Gm10718
predicted gene 10718
chr9_+_3017408 3.853 ENSMUST00000099049.3
Gm10719
predicted gene 10719
chr9_+_3025417 3.845 ENSMUST00000075573.6
Gm10717
predicted gene 10717
chr11_-_84525514 3.756 ENSMUST00000018842.7
Lhx1
LIM homeobox protein 1
chr7_-_62464505 3.620 ENSMUST00000094339.2
Peg12
paternally expressed 12
chr7_-_99353104 3.462 ENSMUST00000169437.1
ENSMUST00000094154.4
Serpinh1

serine (or cysteine) peptidase inhibitor, clade H, member 1

chr9_+_3037111 3.257 ENSMUST00000177969.1
Gm10715
predicted gene 10715
chr17_-_70849644 3.255 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
Tgif1


TGFB-induced factor homeobox 1


chr15_+_79030874 3.119 ENSMUST00000171999.1
ENSMUST00000006544.7
Gcat

glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)


Gene overrepresentation in biological_process category:

Showing 1 to 20 of 196 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.8 17.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 12.8 GO:0006270 DNA replication initiation(GO:0006270)
1.6 6.3 GO:2000768 positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.3 5.1 GO:0051127 positive regulation of actin nucleation(GO:0051127)
1.6 4.9 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 4.7 GO:0021884 forebrain neuron development(GO:0021884)
0.1 4.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.2 4.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.4 4.1 GO:0097421 liver regeneration(GO:0097421)
0.6 3.5 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.1 3.5 GO:0000578 embryonic axis specification(GO:0000578)
0.0 3.2 GO:0008360 regulation of cell shape(GO:0008360)
0.9 2.6 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.5 2.6 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 2.6 GO:0071398 cellular response to fatty acid(GO:0071398)
0.1 2.6 GO:0043029 T cell homeostasis(GO:0043029)
0.6 2.5 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.0 2.5 GO:0008033 tRNA processing(GO:0008033)
0.6 2.4 GO:0097168 condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168)
0.6 2.4 GO:0002074 extraocular skeletal muscle development(GO:0002074) pulmonary myocardium development(GO:0003350) subthalamus development(GO:0021539) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 95 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.5 GO:0000776 kinetochore(GO:0000776)
0.1 5.2 GO:0030904 retromer complex(GO:0030904)
0.1 5.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
1.6 4.9 GO:0005588 collagen type V trimer(GO:0005588)
0.7 4.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 3.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 3.0 GO:0034707 chloride channel complex(GO:0034707)
0.1 3.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 2.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 2.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.8 2.5 GO:0071914 prominosome(GO:0071914)
0.1 2.4 GO:0002102 podosome(GO:0002102)
0.3 2.3 GO:0033269 internode region of axon(GO:0033269)
0.3 2.1 GO:0001520 outer dense fiber(GO:0001520) meiotic spindle(GO:0072687)
0.2 2.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 2.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 2.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.9 GO:0016607 nuclear speck(GO:0016607)
0.1 1.8 GO:0045120 pronucleus(GO:0045120)
0.0 1.8 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 139 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 23.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 9.1 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 7.1 GO:0003682 chromatin binding(GO:0003682)
0.0 5.5 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 5.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 5.0 GO:0003779 actin binding(GO:0003779)
0.1 4.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 4.8 GO:0035064 methylated histone binding(GO:0035064)
0.1 4.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 4.4 GO:0051082 unfolded protein binding(GO:0051082)
0.1 3.3 GO:0070410 co-SMAD binding(GO:0070410)
0.1 3.2 GO:0042805 actinin binding(GO:0042805)
0.0 3.1 GO:0051015 actin filament binding(GO:0051015)
1.0 3.0 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.0 2.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.7 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 2.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2 2.4 GO:0035198 miRNA binding(GO:0035198)
0.3 2.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.7 2.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)