Motif ID: Gli2
Z-value: 0.462
Transcription factors associated with Gli2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Gli2 | ENSMUSG00000048402.8 | Gli2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Gli2 | mm10_v2_chr1_-_119053339_119053370 | -0.21 | 2.5e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.7 | GO:1902460 | regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
0.4 | 1.3 | GO:0050975 | sensory perception of touch(GO:0050975) |
0.2 | 1.1 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
0.2 | 0.7 | GO:1904706 | negative regulation of vascular smooth muscle cell proliferation(GO:1904706) |
0.2 | 0.6 | GO:0070124 | mitochondrial translational initiation(GO:0070124) |
0.2 | 1.5 | GO:0071420 | cellular response to histamine(GO:0071420) |
0.2 | 1.0 | GO:0014054 | positive regulation of gamma-aminobutyric acid secretion(GO:0014054) |
0.1 | 0.7 | GO:0051013 | microtubule severing(GO:0051013) |
0.1 | 1.1 | GO:0071435 | potassium ion export(GO:0071435) |
0.1 | 1.0 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
0.1 | 0.2 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
0.1 | 0.7 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
0.1 | 1.3 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
0.1 | 0.6 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.1 | 1.0 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.1 | 0.2 | GO:2000642 | negative regulation of early endosome to late endosome transport(GO:2000642) |
0.0 | 0.1 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
0.0 | 0.1 | GO:0042713 | sperm ejaculation(GO:0042713) |
0.0 | 0.1 | GO:0034447 | very-low-density lipoprotein particle clearance(GO:0034447) |
0.0 | 0.2 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
0.0 | 0.5 | GO:1904424 | regulation of GTP binding(GO:1904424) |
0.0 | 0.8 | GO:0048266 | behavioral response to pain(GO:0048266) |
0.0 | 0.8 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
0.0 | 0.3 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
0.0 | 0.3 | GO:0015074 | DNA integration(GO:0015074) |
0.0 | 2.5 | GO:0060999 | positive regulation of dendritic spine development(GO:0060999) |
0.0 | 0.7 | GO:2000463 | positive regulation of excitatory postsynaptic potential(GO:2000463) |
0.0 | 0.3 | GO:2000465 | regulation of glycogen (starch) synthase activity(GO:2000465) |
0.0 | 0.2 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
0.0 | 1.0 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
0.0 | 1.5 | GO:0072583 | clathrin-mediated endocytosis(GO:0072583) |
0.0 | 0.4 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
0.0 | 0.1 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
0.0 | 0.5 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.0 | 0.2 | GO:0006817 | phosphate ion transport(GO:0006817) |
0.0 | 0.1 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
0.0 | 0.2 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) |
0.0 | 0.1 | GO:0070589 | cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule metabolic process(GO:0044036) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589) cell wall organization or biogenesis(GO:0071554) |
0.0 | 1.1 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.0 | 0.1 | GO:0030397 | membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081) |
0.0 | 0.5 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
0.0 | 0.0 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
0.0 | 0.3 | GO:0006828 | manganese ion transport(GO:0006828) |
0.0 | 0.1 | GO:0098734 | protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.9 | GO:0030314 | junctional membrane complex(GO:0030314) |
0.1 | 2.6 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
0.1 | 1.5 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
0.1 | 0.5 | GO:0032280 | symmetric synapse(GO:0032280) |
0.1 | 0.5 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
0.1 | 0.3 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.1 | 0.9 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.0 | 1.2 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.0 | 0.5 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 0.1 | GO:0036488 | CHOP-C/EBP complex(GO:0036488) |
0.0 | 0.2 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
0.0 | 0.9 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
0.0 | 0.1 | GO:0005594 | collagen type IX trimer(GO:0005594) |
0.0 | 0.8 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 0.1 | GO:0070876 | SOSS complex(GO:0070876) |
0.0 | 0.1 | GO:0031502 | dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502) |
0.0 | 0.2 | GO:0032009 | early phagosome(GO:0032009) |
0.0 | 0.2 | GO:0071203 | WASH complex(GO:0071203) |
0.0 | 1.3 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 1.4 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 0.1 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
0.0 | 0.2 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.0 | 1.2 | GO:0043204 | perikaryon(GO:0043204) |
0.0 | 0.1 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
0.0 | 0.1 | GO:0072687 | meiotic spindle(GO:0072687) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.3 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
0.2 | 1.2 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
0.2 | 1.5 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.1 | 2.6 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.1 | 1.0 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
0.1 | 1.4 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
0.1 | 0.3 | GO:0047256 | beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256) |
0.1 | 0.3 | GO:2001069 | glycogen binding(GO:2001069) |
0.1 | 0.5 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.1 | 1.7 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
0.1 | 0.2 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
0.1 | 0.9 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.1 | 1.3 | GO:0031489 | myosin V binding(GO:0031489) |
0.1 | 0.8 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.1 | 0.2 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
0.1 | 0.7 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
0.1 | 0.5 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.0 | 0.1 | GO:0034189 | very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437) |
0.0 | 0.8 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.0 | 0.4 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.0 | 0.5 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
0.0 | 1.1 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 0.6 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.0 | 0.2 | GO:0098518 | polynucleotide phosphatase activity(GO:0098518) |
0.0 | 0.2 | GO:1990715 | mRNA CDS binding(GO:1990715) |
0.0 | 0.5 | GO:0017161 | phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003) |
0.0 | 0.8 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 0.2 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
0.0 | 0.2 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
0.0 | 0.7 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
0.0 | 0.8 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
0.0 | 0.1 | GO:0070012 | oligopeptidase activity(GO:0070012) |
0.0 | 0.2 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |