Motif ID: Glis2

Z-value: 1.015


Transcription factors associated with Glis2:

Gene SymbolEntrez IDGene Name
Glis2 ENSMUSG00000014303.7 Glis2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Glis2mm10_v2_chr16_+_4594683_45947350.028.9e-01Click!


Activity profile for motif Glis2.

activity profile for motif Glis2


Sorted Z-values histogram for motif Glis2

Sorted Z-values for motif Glis2



Network of associatons between targets according to the STRING database.



First level regulatory network of Glis2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_87948666 9.454 ENSMUST00000005019.5
Crabp2
cellular retinoic acid binding protein II
chr7_-_103843154 6.067 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr8_+_3631109 4.021 ENSMUST00000004745.8
Stxbp2
syntaxin binding protein 2
chr19_+_7268296 3.924 ENSMUST00000066646.4
Rcor2
REST corepressor 2
chr2_-_54085542 3.373 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr3_-_89322883 3.090 ENSMUST00000029673.5
Efna3
ephrin A3
chr5_+_136083916 2.934 ENSMUST00000042135.7
Rasa4
RAS p21 protein activator 4
chr5_+_136084022 2.840 ENSMUST00000100570.3
Rasa4
RAS p21 protein activator 4
chr7_-_126704736 2.801 ENSMUST00000131415.1
Coro1a
coronin, actin binding protein 1A
chr11_+_101468164 2.569 ENSMUST00000001347.6
Rnd2
Rho family GTPase 2
chr12_+_109544498 2.463 ENSMUST00000126289.1
Meg3
maternally expressed 3
chr3_-_66981279 2.459 ENSMUST00000162098.2
Shox2
short stature homeobox 2
chr4_-_58499398 2.408 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr2_+_4976113 2.356 ENSMUST00000167607.1
ENSMUST00000115010.2
Ucma

upper zone of growth plate and cartilage matrix associated

chr8_-_87472576 2.336 ENSMUST00000034076.8
Cbln1
cerebellin 1 precursor protein
chr7_-_126704816 2.094 ENSMUST00000032949.7
Coro1a
coronin, actin binding protein 1A
chr11_-_106160708 1.996 ENSMUST00000106875.1
Limd2
LIM domain containing 2
chr2_-_57124003 1.985 ENSMUST00000112629.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr11_+_4873951 1.929 ENSMUST00000038570.2
Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr16_-_45724600 1.916 ENSMUST00000096057.4
Tagln3
transgelin 3
chr14_+_55854115 1.912 ENSMUST00000168479.1
Nynrin
NYN domain and retroviral integrase containing
chr4_+_109978004 1.899 ENSMUST00000061187.3
Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr1_-_172329261 1.896 ENSMUST00000062387.2
Kcnj9
potassium inwardly-rectifying channel, subfamily J, member 9
chr2_-_57113053 1.753 ENSMUST00000112627.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr15_-_85581809 1.717 ENSMUST00000023015.7
Wnt7b
wingless-related MMTV integration site 7B
chr19_-_45742873 1.704 ENSMUST00000026241.5
ENSMUST00000026240.7
ENSMUST00000111928.1
Fgf8


fibroblast growth factor 8


chr7_+_28881656 1.690 ENSMUST00000066880.4
Capn12
calpain 12
chr2_+_174330006 1.672 ENSMUST00000109085.1
ENSMUST00000109087.1
ENSMUST00000109084.1
Gnas


GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus


chr17_+_80127447 1.672 ENSMUST00000039205.4
Galm
galactose mutarotase
chr5_-_137533297 1.638 ENSMUST00000111020.1
ENSMUST00000111023.1
Gnb2

guanine nucleotide binding protein (G protein), beta 2

chr4_+_148804420 1.610 ENSMUST00000094464.3
ENSMUST00000122222.1
Casz1

castor zinc finger 1

chr2_-_152830615 1.594 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
Bcl2l1



BCL2-like 1



chr8_-_91801547 1.509 ENSMUST00000093312.4
Irx3
Iroquois related homeobox 3 (Drosophila)
chr2_-_26294550 1.470 ENSMUST00000057224.3
4932418E24Rik
RIKEN cDNA 4932418E24 gene
chr5_+_140419248 1.458 ENSMUST00000100507.3
Eif3b
eukaryotic translation initiation factor 3, subunit B
chr7_-_126799163 1.457 ENSMUST00000032934.5
Aldoa
aldolase A, fructose-bisphosphate
chr6_-_124911636 1.457 ENSMUST00000032217.1
Lag3
lymphocyte-activation gene 3
chr6_-_125165576 1.453 ENSMUST00000183272.1
ENSMUST00000182052.1
ENSMUST00000182277.1
Gapdh


glyceraldehyde-3-phosphate dehydrogenase


chr8_+_3493135 1.443 ENSMUST00000061508.7
Zfp358
zinc finger protein 358
chr6_-_48840988 1.404 ENSMUST00000164733.1
Tmem176b
transmembrane protein 176B
chr8_-_91801948 1.401 ENSMUST00000175795.1
Irx3
Iroquois related homeobox 3 (Drosophila)
chr11_-_102230091 1.397 ENSMUST00000008999.5
Hdac5
histone deacetylase 5
chr8_-_111743799 1.361 ENSMUST00000166232.2
Bcar1
breast cancer anti-estrogen resistance 1
chr7_-_126799134 1.353 ENSMUST00000087566.4
Aldoa
aldolase A, fructose-bisphosphate
chr11_-_102230127 1.268 ENSMUST00000107150.1
ENSMUST00000156337.1
ENSMUST00000107151.2
ENSMUST00000107152.2
Hdac5



histone deacetylase 5



chr7_+_127746775 1.230 ENSMUST00000033081.7
Fbxl19
F-box and leucine-rich repeat protein 19
chr5_+_115327125 1.203 ENSMUST00000031513.7
Srsf9
serine/arginine-rich splicing factor 9
chr9_-_106465940 1.196 ENSMUST00000164834.1
Gpr62
G protein-coupled receptor 62
chr10_-_127189981 1.191 ENSMUST00000019611.7
Arhgef25
Rho guanine nucleotide exchange factor (GEF) 25
chr10_+_36974536 1.161 ENSMUST00000019911.7
Hdac2
histone deacetylase 2
chr7_-_35647441 1.145 ENSMUST00000118501.1
Pdcd5
programmed cell death 5
chr6_+_120666388 1.125 ENSMUST00000112686.1
Cecr2
cat eye syndrome chromosome region, candidate 2
chr17_-_46629420 1.120 ENSMUST00000044442.8
Ptk7
PTK7 protein tyrosine kinase 7
chr3_+_87971071 1.112 ENSMUST00000090973.5
Nes
nestin
chr16_-_32099697 1.095 ENSMUST00000155966.1
ENSMUST00000096109.4
Pigx

phosphatidylinositol glycan anchor biosynthesis, class X

chr7_-_35647127 1.078 ENSMUST00000120714.1
Pdcd5
programmed cell death 5
chr3_+_87971129 1.071 ENSMUST00000160694.1
Nes
nestin
chr8_+_58911755 1.068 ENSMUST00000062978.6
BC030500
cDNA sequence BC030500
chr4_+_115059507 1.059 ENSMUST00000162489.1
Tal1
T cell acute lymphocytic leukemia 1
chr17_-_45549655 1.039 ENSMUST00000180252.1
Tmem151b
transmembrane protein 151B
chr6_-_48841098 1.010 ENSMUST00000101429.4
Tmem176b
transmembrane protein 176B
chr8_+_58912257 1.007 ENSMUST00000160055.1
BC030500
cDNA sequence BC030500
chr5_-_137533212 0.993 ENSMUST00000111038.1
ENSMUST00000143495.1
Epo
Gnb2
erythropoietin
guanine nucleotide binding protein (G protein), beta 2
chr12_+_73123709 0.960 ENSMUST00000021523.6
Mnat1
menage a trois 1
chr10_+_80016901 0.944 ENSMUST00000105373.1
Hmha1
histocompatibility (minor) HA-1
chr5_-_134614953 0.939 ENSMUST00000036362.6
ENSMUST00000077636.4
Lat2

linker for activation of T cells family, member 2

chr2_+_26583858 0.922 ENSMUST00000100290.5
ENSMUST00000102907.5
Egfl7

EGF-like domain 7

chr8_-_40634776 0.919 ENSMUST00000048898.10
ENSMUST00000174205.1
Mtmr7

myotubularin related protein 7

chr17_-_34118476 0.915 ENSMUST00000095347.5
Brd2
bromodomain containing 2
chr9_+_107975529 0.914 ENSMUST00000035216.4
Uba7
ubiquitin-like modifier activating enzyme 7
chr11_+_77493408 0.902 ENSMUST00000037285.3
ENSMUST00000100812.3
Git1

G protein-coupled receptor kinase-interactor 1

chr6_-_48841373 0.897 ENSMUST00000166247.1
Tmem176b
transmembrane protein 176B
chr8_-_40634750 0.832 ENSMUST00000173957.1
Mtmr7
myotubularin related protein 7
chr19_+_8735808 0.824 ENSMUST00000049424.9
Wdr74
WD repeat domain 74
chr7_-_142061021 0.799 ENSMUST00000084418.2
Mob2
MOB kinase activator 2
chr5_+_115279666 0.798 ENSMUST00000040421.4
Coq5
coenzyme Q5 homolog, methyltransferase (yeast)
chr10_+_127266256 0.793 ENSMUST00000026479.9
Dctn2
dynactin 2
chr19_+_55741810 0.790 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr5_-_137533170 0.787 ENSMUST00000168746.1
ENSMUST00000170293.1
Gnb2

guanine nucleotide binding protein (G protein), beta 2

chr10_-_128211788 0.778 ENSMUST00000061995.8
Spryd4
SPRY domain containing 4
chr16_+_59471775 0.746 ENSMUST00000023407.5
ENSMUST00000120667.1
ENSMUST00000120674.1
Mina


myc induced nuclear antigen


chrX_+_36598199 0.718 ENSMUST00000073339.6
Pgrmc1
progesterone receptor membrane component 1
chr5_-_131538687 0.703 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr5_-_110839575 0.702 ENSMUST00000145318.1
Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr11_+_98795495 0.691 ENSMUST00000037915.2
Msl1
male-specific lethal 1 homolog (Drosophila)
chr8_+_105690906 0.678 ENSMUST00000062574.6
Rltpr
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr7_-_114636299 0.672 ENSMUST00000032906.4
ENSMUST00000032907.7
Calca

calcitonin/calcitonin-related polypeptide, alpha

chr5_-_122989086 0.661 ENSMUST00000046073.9
Kdm2b
lysine (K)-specific demethylase 2B
chr7_-_122101735 0.655 ENSMUST00000139456.1
ENSMUST00000106471.2
ENSMUST00000123296.1
ENSMUST00000033157.3
Ndufab1



NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1



chr8_-_58911627 0.653 ENSMUST00000077447.4
Galntl6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr8_-_109251698 0.647 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr10_+_36974558 0.633 ENSMUST00000105510.1
Hdac2
histone deacetylase 2
chr12_-_108835845 0.631 ENSMUST00000021693.3
Slc25a29
solute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29
chr8_-_120101473 0.623 ENSMUST00000034280.7
Zdhhc7
zinc finger, DHHC domain containing 7
chr12_+_109545390 0.622 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr5_-_110387090 0.598 ENSMUST00000056124.6
Fbrsl1
fibrosin-like 1
chr14_+_64588112 0.594 ENSMUST00000181808.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr5_-_122989260 0.591 ENSMUST00000118027.1
Kdm2b
lysine (K)-specific demethylase 2B
chr2_-_152831112 0.590 ENSMUST00000128172.1
Bcl2l1
BCL2-like 1
chr11_-_70669283 0.574 ENSMUST00000129434.1
ENSMUST00000018431.6
Spag7

sperm associated antigen 7

chr11_-_84819450 0.567 ENSMUST00000018549.7
Mrm1
mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
chr11_+_70018421 0.559 ENSMUST00000108588.1
Dlg4
discs, large homolog 4 (Drosophila)
chr2_+_68861433 0.552 ENSMUST00000028426.2
Cers6
ceramide synthase 6
chr17_-_57087729 0.552 ENSMUST00000071135.5
Tubb4a
tubulin, beta 4A class IVA
chrX_-_10216437 0.551 ENSMUST00000115534.1
Rpgr
retinitis pigmentosa GTPase regulator
chr5_-_110839757 0.551 ENSMUST00000056937.5
Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr13_-_58402476 0.547 ENSMUST00000175847.1
ENSMUST00000043269.7
ENSMUST00000177060.1
Hnrnpk


heterogeneous nuclear ribonucleoprotein K


chr7_+_44572370 0.547 ENSMUST00000002274.8
Napsa
napsin A aspartic peptidase
chr1_+_191718389 0.543 ENSMUST00000110856.1
ENSMUST00000130876.1
Lpgat1

lysophosphatidylglycerol acyltransferase 1

chrX_-_7947553 0.539 ENSMUST00000133349.1
Hdac6
histone deacetylase 6
chr17_-_56830916 0.528 ENSMUST00000002444.7
ENSMUST00000086801.5
Rfx2

regulatory factor X, 2 (influences HLA class II expression)

chr8_-_23257009 0.512 ENSMUST00000121783.1
Golga7
golgi autoantigen, golgin subfamily a, 7
chr7_+_144915124 0.494 ENSMUST00000033388.5
ENSMUST00000105895.1
Oraov1

oral cancer overexpressed 1

chr5_+_37338455 0.487 ENSMUST00000056365.8
Evc2
Ellis van Creveld syndrome 2
chr7_+_35334175 0.481 ENSMUST00000032705.6
ENSMUST00000085556.3
Rhpn2

rhophilin, Rho GTPase binding protein 2

chr11_+_72042455 0.478 ENSMUST00000021164.3
Fam64a
family with sequence similarity 64, member A
chr12_-_108275409 0.476 ENSMUST00000136175.1
Ccdc85c
coiled-coil domain containing 85C
chr2_-_3512746 0.467 ENSMUST00000027961.5
ENSMUST00000056700.7
Hspa14
Hspa14
heat shock protein 14
heat shock protein 14
chr12_-_80643799 0.461 ENSMUST00000166931.1
Erh
enhancer of rudimentary homolog (Drosophila)
chr8_-_23257043 0.454 ENSMUST00000051094.6
Golga7
golgi autoantigen, golgin subfamily a, 7
chr7_-_30193098 0.446 ENSMUST00000108196.1
Capns1
calpain, small subunit 1
chr9_+_21723576 0.441 ENSMUST00000034713.7
Ldlr
low density lipoprotein receptor
chr2_+_119351222 0.406 ENSMUST00000028780.3
Chac1
ChaC, cation transport regulator 1
chr11_-_101170327 0.401 ENSMUST00000123864.1
Plekhh3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr19_+_6401675 0.398 ENSMUST00000113471.1
ENSMUST00000113469.2
Rasgrp2

RAS, guanyl releasing protein 2

chr7_+_45872772 0.393 ENSMUST00000002855.5
ENSMUST00000107719.1
Kdelr1

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1

chr11_+_103649498 0.392 ENSMUST00000057870.2
Rprml
reprimo-like
chr11_-_100650693 0.386 ENSMUST00000103119.3
Zfp385c
zinc finger protein 385C
chr2_+_105668888 0.385 ENSMUST00000111086.4
ENSMUST00000111087.3
Pax6

paired box gene 6

chr7_-_30195046 0.380 ENSMUST00000001845.5
Capns1
calpain, small subunit 1
chr16_-_34573526 0.378 ENSMUST00000114961.1
Kalrn
kalirin, RhoGEF kinase
chr6_+_113604749 0.370 ENSMUST00000035725.5
Brk1
BRICK1, SCAR/WAVE actin-nucleating complex subunit
chr7_-_19715395 0.366 ENSMUST00000032555.9
ENSMUST00000093552.5
Tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

chr1_-_192092540 0.357 ENSMUST00000085573.6
Traf5
TNF receptor-associated factor 5
chr17_-_57031468 0.343 ENSMUST00000007814.8
Khsrp
KH-type splicing regulatory protein
chr9_-_22307638 0.341 ENSMUST00000086278.6
Zfp810
zinc finger protein 810
chrX_-_10216918 0.340 ENSMUST00000072393.2
ENSMUST00000044598.6
ENSMUST00000073392.4
ENSMUST00000115533.1
ENSMUST00000115532.1
Rpgr




retinitis pigmentosa GTPase regulator




chr6_-_51469869 0.335 ENSMUST00000114459.1
ENSMUST00000069949.6
Hnrnpa2b1

heterogeneous nuclear ribonucleoprotein A2/B1

chr9_+_54538984 0.331 ENSMUST00000060242.5
ENSMUST00000118413.1
Sh2d7

SH2 domain containing 7

chr5_+_142629537 0.327 ENSMUST00000036872.9
ENSMUST00000110778.1
Wipi2

WD repeat domain, phosphoinositide interacting 2

chr2_-_154569720 0.317 ENSMUST00000000894.5
E2f1
E2F transcription factor 1
chr7_+_90130227 0.314 ENSMUST00000049537.7
Picalm
phosphatidylinositol binding clathrin assembly protein
chr5_+_119834663 0.313 ENSMUST00000018407.6
Tbx5
T-box 5
chr5_+_30105161 0.311 ENSMUST00000058045.4
Gareml
GRB2 associated, regulator of MAPK1-like
chr5_-_123524124 0.301 ENSMUST00000111586.1
ENSMUST00000031385.6
ENSMUST00000111587.3
Diablo


diablo homolog (Drosophila)


chr4_+_118620799 0.298 ENSMUST00000030501.8
Ebna1bp2
EBNA1 binding protein 2
chr9_-_121839460 0.295 ENSMUST00000135986.2
Ccdc13
coiled-coil domain containing 13
chr4_-_117914968 0.290 ENSMUST00000036156.5
Ipo13
importin 13
chr3_+_103020546 0.280 ENSMUST00000029446.8
Csde1
cold shock domain containing E1, RNA binding
chr1_-_74284636 0.274 ENSMUST00000178235.1
ENSMUST00000006462.7
Aamp

angio-associated migratory protein

chr16_+_32099781 0.273 ENSMUST00000115168.2
Cep19
centrosomal protein 19
chr2_+_118111876 0.265 ENSMUST00000039559.8
Thbs1
thrombospondin 1
chr16_+_29209695 0.263 ENSMUST00000089824.4
Hrasls
HRAS-like suppressor
chr13_-_34077992 0.263 ENSMUST00000056427.8
Tubb2a
tubulin, beta 2A class IIA
chr6_+_48647224 0.251 ENSMUST00000078223.3
Gimap8
GTPase, IMAP family member 8
chr6_-_51469836 0.250 ENSMUST00000090002.7
Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chr3_+_130180882 0.235 ENSMUST00000106353.1
ENSMUST00000080335.4
Col25a1

collagen, type XXV, alpha 1

chr10_-_127195709 0.230 ENSMUST00000038217.7
ENSMUST00000130855.1
ENSMUST00000116229.1
ENSMUST00000144322.1
Dtx3



deltex 3 homolog (Drosophila)



chrX_-_152368680 0.216 ENSMUST00000070316.5
Gpr173
G-protein coupled receptor 173
chr8_+_35587780 0.212 ENSMUST00000037666.5
Mfhas1
malignant fibrous histiocytoma amplified sequence 1
chr1_+_86303221 0.202 ENSMUST00000113306.2
B3gnt7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr2_+_105668935 0.186 ENSMUST00000142772.1
Pax6
paired box gene 6
chr8_+_25754492 0.178 ENSMUST00000167899.1
Gm17484
predicted gene, 17484
chr7_+_3289012 0.168 ENSMUST00000164553.1
Myadm
myeloid-associated differentiation marker
chr2_+_90677208 0.163 ENSMUST00000057481.6
Nup160
nucleoporin 160
chr7_-_133122615 0.158 ENSMUST00000167218.1
Ctbp2
C-terminal binding protein 2
chr14_+_60378242 0.153 ENSMUST00000022561.6
Amer2
APC membrane recruitment 2
chr3_+_66981352 0.140 ENSMUST00000162036.1
Rsrc1
arginine/serine-rich coiled-coil 1
chr17_+_17831004 0.139 ENSMUST00000172097.2
4930546H06Rik
RIKEN cDNA 4930546H06 gene
chr11_+_46436925 0.131 ENSMUST00000152119.1
ENSMUST00000140027.1
ENSMUST00000020665.6
ENSMUST00000170928.1
ENSMUST00000109231.1
ENSMUST00000109232.3
ENSMUST00000128940.1
Med7






mediator complex subunit 7






chr1_-_93801840 0.127 ENSMUST00000112890.2
ENSMUST00000027503.7
Dtymk

deoxythymidylate kinase

chr2_+_83644435 0.116 ENSMUST00000081591.6
Zc3h15
zinc finger CCCH-type containing 15
chr9_-_108083330 0.095 ENSMUST00000159372.1
ENSMUST00000160249.1
Rnf123

ring finger protein 123

chr12_-_54862783 0.095 ENSMUST00000078124.7
Cfl2
cofilin 2, muscle
chr17_+_29679247 0.091 ENSMUST00000129864.1
Cmtr1
cap methyltransferase 1
chr10_-_81060134 0.050 ENSMUST00000005067.5
Sgta
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr4_-_42661893 0.040 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr1_-_153487639 0.039 ENSMUST00000042141.5
Dhx9
DEAH (Asp-Glu-Ala-His) box polypeptide 9
chr1_+_172126750 0.034 ENSMUST00000075895.2
ENSMUST00000111252.3
Pex19

peroxisomal biogenesis factor 19

chr2_+_91096744 0.024 ENSMUST00000132741.2
Spi1
spleen focus forming virus (SFFV) proviral integration oncogene
chrX_-_8206475 0.021 ENSMUST00000089403.3
ENSMUST00000077595.5
ENSMUST00000089402.3
ENSMUST00000082320.5
Porcn



porcupine homolog (Drosophila)



chr17_+_15053059 0.019 ENSMUST00000040594.8
Ermard
ER membrane associated RNA degradation
chr17_-_34122311 0.008 ENSMUST00000025193.6
Brd2
bromodomain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.1 GO:0015671 oxygen transport(GO:0015671)
0.9 3.7 GO:0051866 general adaptation syndrome(GO:0051866)
0.9 12.0 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.8 4.9 GO:0032796 uropod organization(GO:0032796)
0.6 2.4 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.6 1.7 GO:0072070 establishment or maintenance of polarity of embryonic epithelium(GO:0016332) loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.6 1.7 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.5 2.2 GO:0046898 response to cycloheximide(GO:0046898)
0.5 5.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.5 1.5 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.5 3.2 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.4 1.6 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) retinal rod cell differentiation(GO:0060221)
0.4 1.5 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.4 1.8 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.4 1.1 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.3 1.7 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.3 1.0 GO:1902219 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.3 1.5 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.3 2.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.3 1.3 GO:0021993 initiation of neural tube closure(GO:0021993)
0.2 1.9 GO:0015074 DNA integration(GO:0015074)
0.2 0.7 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 0.7 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.2 0.7 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.2 2.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040) negative regulation of protein folding(GO:1903333)
0.2 0.5 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.2 1.6 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 1.7 GO:0006012 galactose metabolic process(GO:0006012)
0.2 2.3 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 0.5 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.2 1.1 GO:0001842 neural fold formation(GO:0001842)
0.2 4.0 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.2 2.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.4 GO:0010899 regulation of phosphatidylcholine catabolic process(GO:0010899)
0.1 5.8 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 1.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 0.5 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.1 3.1 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.9 GO:0001771 immunological synapse formation(GO:0001771)
0.1 1.4 GO:0035729 response to hepatocyte growth factor(GO:0035728) cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.1 0.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.7 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.0 GO:0007512 adult heart development(GO:0007512)
0.1 0.8 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 1.8 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.1 0.3 GO:0010752 negative regulation of antigen processing and presentation(GO:0002578) negative regulation of nitric oxide mediated signal transduction(GO:0010751) regulation of cGMP-mediated signaling(GO:0010752) negative regulation of plasminogen activation(GO:0010757)
0.1 0.3 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 0.3 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
0.1 0.6 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.5 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 3.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.1 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.1 0.3 GO:1905049 negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.1 1.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 1.6 GO:0010107 potassium ion import(GO:0010107)
0.1 0.9 GO:0043303 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.1 0.5 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.6 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.1 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.8 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.3 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.4 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 1.2 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 2.1 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.8 GO:0032402 melanosome transport(GO:0032402)
0.0 1.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.6 GO:2000821 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) regulation of grooming behavior(GO:2000821)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.6 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.9 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.7 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.0 0.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 2.7 GO:0007498 mesoderm development(GO:0007498)
0.0 0.7 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.3 GO:0044804 nucleophagy(GO:0044804)
0.0 0.3 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 3.4 GO:0007050 cell cycle arrest(GO:0007050)
0.0 1.1 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.4 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.5 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.0 0.2 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.0 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.1 GO:0030836 positive regulation of actin filament depolymerization(GO:0030836)
0.0 0.6 GO:0046513 ceramide biosynthetic process(GO:0046513)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0044194 cytolytic granule(GO:0044194)
0.8 6.1 GO:0005833 hemoglobin complex(GO:0005833)
0.6 4.5 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.4 5.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.4 1.1 GO:0033193 Lsd1/2 complex(GO:0033193)
0.3 0.3 GO:0097418 neurofibrillary tangle(GO:0097418)
0.3 1.1 GO:0090537 CERF complex(GO:0090537)
0.3 2.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 1.5 GO:0097452 GAIT complex(GO:0097452)
0.2 2.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 4.9 GO:0001891 phagocytic cup(GO:0001891)
0.2 1.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.7 GO:0072487 MSL complex(GO:0072487)
0.1 5.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 3.8 GO:0016235 aggresome(GO:0016235)
0.1 1.0 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.8 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.6 GO:0033269 internode region of axon(GO:0033269)
0.1 1.0 GO:0005675 holo TFIIH complex(GO:0005675)
0.1 0.5 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 0.7 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.3 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 0.8 GO:0005869 dynactin complex(GO:0005869)
0.0 0.6 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.5 GO:0034709 methylosome(GO:0034709)
0.0 0.7 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 4.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 2.2 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.9 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 2.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 2.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.0 GO:0005769 early endosome(GO:0005769)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.5 GO:0019841 retinol binding(GO:0019841)
1.5 6.1 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.7 2.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.6 4.5 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.6 1.7 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.5 4.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.5 1.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.5 1.5 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.5 2.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.4 1.7 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.4 2.4 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.4 1.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 1.0 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.3 1.7 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.3 2.2 GO:0051434 BH3 domain binding(GO:0051434)
0.2 2.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 0.9 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 4.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 4.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.5 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 2.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.6 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.7 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.5 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.6 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.1 0.4 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 1.8 GO:0017161 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.1 1.9 GO:0042165 neurotransmitter binding(GO:0042165)
0.1 1.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.6 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 3.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.4 GO:0015288 porin activity(GO:0015288)
0.1 0.6 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0035615 clathrin heavy chain binding(GO:0032050) clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.8 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 1.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.4 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.5 GO:0019707 protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.7 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.0 1.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 2.6 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 3.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.1 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 1.3 GO:0051087 chaperone binding(GO:0051087)
0.0 0.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.9 GO:0035496 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062)
0.0 0.7 GO:0020037 heme binding(GO:0020037)
0.0 3.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.7 GO:0005179 hormone activity(GO:0005179)