Motif ID: Glis3
Z-value: 0.615
Transcription factors associated with Glis3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Glis3 | ENSMUSG00000052942.7 | Glis3 |
Glis3 | ENSMUSG00000091294.1 | Glis3 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Glis3 | mm10_v2_chr19_-_28680077_28680122 | -0.11 | 5.3e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 4.4 | GO:0042414 | epinephrine metabolic process(GO:0042414) |
1.0 | 9.1 | GO:0010587 | miRNA catabolic process(GO:0010587) |
1.0 | 3.9 | GO:0097374 | sensory neuron axon guidance(GO:0097374) |
0.8 | 4.2 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
0.8 | 2.3 | GO:0070172 | oculomotor nerve development(GO:0021557) positive regulation of tooth mineralization(GO:0070172) |
0.6 | 2.9 | GO:0048133 | NK T cell differentiation(GO:0001865) germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728) |
0.6 | 1.7 | GO:0003032 | detection of oxygen(GO:0003032) |
0.5 | 2.2 | GO:0051305 | chromosome movement towards spindle pole(GO:0051305) |
0.5 | 1.5 | GO:0071649 | regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) |
0.4 | 1.7 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
0.4 | 1.2 | GO:0071336 | lung growth(GO:0060437) positive regulation of fat cell proliferation(GO:0070346) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338) |
0.4 | 1.1 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
0.3 | 2.7 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.3 | 1.0 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
0.3 | 8.8 | GO:0035115 | embryonic forelimb morphogenesis(GO:0035115) |
0.3 | 1.0 | GO:0072070 | establishment or maintenance of polarity of embryonic epithelium(GO:0016332) trachea cartilage morphogenesis(GO:0060535) loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236) |
0.3 | 1.0 | GO:0072718 | response to cisplatin(GO:0072718) |
0.3 | 1.5 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
0.3 | 5.0 | GO:0021521 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
0.3 | 1.0 | GO:0003431 | growth plate cartilage chondrocyte development(GO:0003431) |
0.2 | 1.6 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
0.2 | 4.1 | GO:0038092 | nodal signaling pathway(GO:0038092) |
0.2 | 1.8 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
0.2 | 1.2 | GO:0032346 | positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) |
0.2 | 1.6 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) regulation of wound healing, spreading of epidermal cells(GO:1903689) |
0.2 | 0.6 | GO:0033128 | positive regulation of reciprocal meiotic recombination(GO:0010845) negative regulation of histone phosphorylation(GO:0033128) |
0.2 | 0.8 | GO:0043973 | histone H3-K4 acetylation(GO:0043973) |
0.2 | 1.3 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) hydrogen sulfide biosynthetic process(GO:0070814) |
0.2 | 0.5 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
0.2 | 0.5 | GO:0003100 | angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) regulation of systemic arterial blood pressure by endothelin(GO:0003100) beta selection(GO:0043366) |
0.2 | 1.7 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.2 | 0.5 | GO:0003360 | brainstem development(GO:0003360) |
0.2 | 1.0 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.1 | 5.0 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
0.1 | 1.8 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
0.1 | 2.6 | GO:0051602 | response to electrical stimulus(GO:0051602) |
0.1 | 1.0 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
0.1 | 0.7 | GO:0001771 | immunological synapse formation(GO:0001771) |
0.1 | 0.4 | GO:0046898 | response to cycloheximide(GO:0046898) |
0.1 | 0.6 | GO:0007296 | vitellogenesis(GO:0007296) |
0.1 | 0.4 | GO:0030240 | skeletal muscle thin filament assembly(GO:0030240) |
0.1 | 0.4 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
0.1 | 0.9 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
0.1 | 0.3 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
0.1 | 1.1 | GO:0002467 | germinal center formation(GO:0002467) |
0.1 | 1.3 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
0.1 | 0.2 | GO:0060903 | positive regulation of meiosis I(GO:0060903) |
0.0 | 1.5 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 0.9 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.0 | 1.9 | GO:0060325 | face morphogenesis(GO:0060325) |
0.0 | 2.5 | GO:0002209 | behavioral fear response(GO:0001662) behavioral defense response(GO:0002209) |
0.0 | 0.7 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
0.0 | 0.9 | GO:0071385 | cellular response to glucocorticoid stimulus(GO:0071385) |
0.0 | 0.3 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
0.0 | 0.4 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
0.0 | 1.4 | GO:1902017 | regulation of cilium assembly(GO:1902017) |
0.0 | 0.5 | GO:0010667 | negative regulation of cardiac muscle cell apoptotic process(GO:0010667) |
0.0 | 1.3 | GO:0022904 | respiratory electron transport chain(GO:0022904) |
0.0 | 0.6 | GO:0035066 | positive regulation of histone acetylation(GO:0035066) |
0.0 | 0.3 | GO:0090190 | positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) |
0.0 | 0.8 | GO:0010762 | regulation of fibroblast migration(GO:0010762) |
0.0 | 1.2 | GO:0008584 | male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546) |
0.0 | 0.2 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
0.0 | 1.2 | GO:0098792 | xenophagy(GO:0098792) |
0.0 | 1.3 | GO:0008203 | cholesterol metabolic process(GO:0008203) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 2.5 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.3 | 3.1 | GO:0016589 | NURF complex(GO:0016589) |
0.2 | 1.6 | GO:0042382 | paraspeckles(GO:0042382) |
0.2 | 4.4 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.2 | 0.5 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
0.2 | 2.2 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
0.2 | 1.1 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
0.1 | 9.1 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.1 | 0.9 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.1 | 0.7 | GO:0072487 | MSL complex(GO:0072487) |
0.1 | 1.0 | GO:0005642 | annulate lamellae(GO:0005642) |
0.1 | 1.8 | GO:0001650 | fibrillar center(GO:0001650) |
0.1 | 1.4 | GO:0097539 | ciliary transition fiber(GO:0097539) |
0.1 | 0.6 | GO:0033503 | HULC complex(GO:0033503) |
0.1 | 1.0 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.1 | 1.4 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.1 | 1.7 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.1 | 1.8 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
0.1 | 0.4 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
0.0 | 4.4 | GO:0016605 | PML body(GO:0016605) |
0.0 | 0.8 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.0 | 1.5 | GO:0031519 | PcG protein complex(GO:0031519) |
0.0 | 0.7 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 2.1 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 8.9 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 0.5 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 1.5 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
0.0 | 0.1 | GO:0016580 | Sin3 complex(GO:0016580) |
0.0 | 0.6 | GO:0090544 | BAF-type complex(GO:0090544) |
0.0 | 0.8 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 1.5 | GO:0016607 | nuclear speck(GO:0016607) |
0.0 | 0.9 | GO:0070469 | respiratory chain(GO:0070469) |
0.0 | 1.3 | GO:0032993 | protein-DNA complex(GO:0032993) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 4.4 | GO:0035240 | dopamine binding(GO:0035240) |
0.6 | 1.7 | GO:0005534 | galactose binding(GO:0005534) |
0.5 | 9.1 | GO:0035198 | miRNA binding(GO:0035198) |
0.4 | 1.5 | GO:0050700 | CARD domain binding(GO:0050700) |
0.4 | 1.8 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
0.3 | 1.0 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
0.3 | 2.9 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.3 | 1.2 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
0.3 | 1.8 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
0.2 | 1.0 | GO:1902379 | chemoattractant activity involved in axon guidance(GO:1902379) |
0.2 | 1.0 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
0.2 | 2.5 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.2 | 4.1 | GO:0070410 | co-SMAD binding(GO:0070410) |
0.1 | 1.8 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
0.1 | 1.1 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.1 | 0.6 | GO:0008494 | translation activator activity(GO:0008494) |
0.1 | 2.7 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.1 | 1.2 | GO:0070700 | BMP receptor binding(GO:0070700) |
0.1 | 1.5 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
0.1 | 0.9 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
0.1 | 0.5 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
0.1 | 1.3 | GO:0031386 | protein tag(GO:0031386) |
0.1 | 0.5 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
0.1 | 0.8 | GO:0030274 | LIM domain binding(GO:0030274) |
0.1 | 1.0 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.1 | 2.2 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.1 | 2.4 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.1 | 1.3 | GO:0032452 | histone demethylase activity(GO:0032452) |
0.1 | 2.1 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
0.1 | 0.5 | GO:0051022 | Rho GDP-dissociation inhibitor binding(GO:0051022) |
0.1 | 1.7 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
0.1 | 1.3 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.4 | GO:0051434 | BH3 domain binding(GO:0051434) |
0.0 | 1.0 | GO:0018602 | sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635) |
0.0 | 5.6 | GO:0001047 | core promoter binding(GO:0001047) |
0.0 | 0.6 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 1.5 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.0 | 1.0 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 0.9 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 0.3 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.0 | 19.5 | GO:0043565 | sequence-specific DNA binding(GO:0043565) |
0.0 | 1.4 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.1 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.0 | 0.8 | GO:0019003 | GDP binding(GO:0019003) |
0.0 | 0.3 | GO:0003713 | transcription coactivator activity(GO:0003713) |