Motif ID: Glis3

Z-value: 0.615


Transcription factors associated with Glis3:

Gene SymbolEntrez IDGene Name
Glis3 ENSMUSG00000052942.7 Glis3
Glis3 ENSMUSG00000091294.1 Glis3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Glis3mm10_v2_chr19_-_28680077_28680122-0.115.3e-01Click!


Activity profile for motif Glis3.

activity profile for motif Glis3


Sorted Z-values histogram for motif Glis3

Sorted Z-values for motif Glis3



Network of associatons between targets according to the STRING database.



First level regulatory network of Glis3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_134018829 9.057 ENSMUST00000051674.2
Lin28a
lin-28 homolog A (C. elegans)
chr3_+_107595031 5.593 ENSMUST00000014747.1
Alx3
aristaless-like homeobox 3
chr8_-_87959560 5.030 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr7_-_49636847 4.963 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr12_+_109743787 4.426 ENSMUST00000183068.1
Mirg
miRNA containing gene
chr7_-_142899985 4.426 ENSMUST00000000219.3
Th
tyrosine hydroxylase
chr17_-_70851189 4.134 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr5_-_24527276 3.856 ENSMUST00000088311.4
Gbx1
gastrulation brain homeobox 1
chr3_-_66981279 3.159 ENSMUST00000162098.2
Shox2
short stature homeobox 2
chr9_-_48835932 2.944 ENSMUST00000093852.3
Zbtb16
zinc finger and BTB domain containing 16
chr7_-_142657466 2.732 ENSMUST00000097936.2
ENSMUST00000000033.5
Igf2

insulin-like growth factor 2

chr13_-_29984219 2.399 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr13_-_40730416 2.276 ENSMUST00000021787.5
Tfap2a
transcription factor AP-2, alpha
chr11_-_97187872 2.161 ENSMUST00000001479.4
Kpnb1
karyopherin (importin) beta 1
chr7_+_45017953 2.019 ENSMUST00000044111.7
Rras
Harvey rat sarcoma oncogene, subgroup R
chr6_+_88198656 1.802 ENSMUST00000015197.7
Gata2
GATA binding protein 2
chr11_-_102317860 1.774 ENSMUST00000107117.2
Ubtf
upstream binding transcription factor, RNA polymerase I
chr13_+_44730726 1.750 ENSMUST00000173704.1
ENSMUST00000044608.7
ENSMUST00000173367.1
Jarid2


jumonji, AT rich interactive domain 2


chr2_+_32646586 1.692 ENSMUST00000009705.7
ENSMUST00000167841.1
Eng

endoglin

chr16_+_20673517 1.644 ENSMUST00000115460.1
Eif4g1
eukaryotic translation initiation factor 4, gamma 1
chr10_+_127739516 1.644 ENSMUST00000054287.7
Zbtb39
zinc finger and BTB domain containing 39
chrX_+_101429555 1.611 ENSMUST00000033673.6
Nono
non-POU-domain-containing, octamer binding protein
chrX_-_142966709 1.578 ENSMUST00000041317.2
Ammecr1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr13_+_37826225 1.563 ENSMUST00000128570.1
Rreb1
ras responsive element binding protein 1
chr2_+_131234043 1.521 ENSMUST00000041362.5
ENSMUST00000110199.2
Mavs

mitochondrial antiviral signaling protein

chr3_+_66981352 1.463 ENSMUST00000162036.1
Rsrc1
arginine/serine-rich coiled-coil 1
chr2_+_29890534 1.419 ENSMUST00000113764.3
Odf2
outer dense fiber of sperm tails 2
chr1_-_93445642 1.382 ENSMUST00000042498.7
Hdlbp
high density lipoprotein (HDL) binding protein
chr1_+_167001457 1.352 ENSMUST00000126198.1
Fam78b
family with sequence similarity 78, member B
chr6_+_30048062 1.342 ENSMUST00000115209.1
ENSMUST00000115200.1
ENSMUST00000115204.1
Nrf1


nuclear respiratory factor 1


chrM_+_8600 1.257 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr13_+_118714678 1.243 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr11_+_3289880 1.215 ENSMUST00000110043.1
ENSMUST00000094471.3
Patz1

POZ (BTB) and AT hook containing zinc finger 1

chr6_+_30047979 1.208 ENSMUST00000115212.1
ENSMUST00000123194.1
ENSMUST00000115211.1
ENSMUST00000115206.1
ENSMUST00000133928.1
ENSMUST00000115208.1
Nrf1





nuclear respiratory factor 1





chr13_+_38345716 1.179 ENSMUST00000171970.1
Bmp6
bone morphogenetic protein 6
chr10_-_13474361 1.175 ENSMUST00000105547.1
Phactr2
phosphatase and actin regulator 2
chr11_+_69632927 1.162 ENSMUST00000018909.3
Fxr2
fragile X mental retardation, autosomal homolog 2
chr11_+_98927785 1.095 ENSMUST00000107474.1
Rara
retinoic acid receptor, alpha
chr19_+_46305682 1.079 ENSMUST00000111881.2
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr2_-_156111863 1.052 ENSMUST00000154889.1
ENSMUST00000079312.3
ENSMUST00000153634.1
ENSMUST00000133921.1
ENSMUST00000184265.1
ENSMUST00000109607.3
ENSMUST00000109608.2
ENSMUST00000131377.1
ENSMUST00000183518.1
Cpne1






Rbm12
RP23-220D12.12
copine I






RNA binding motif protein 12
RNA-binding protein 12
chr4_+_63215402 1.034 ENSMUST00000036300.6
Col27a1
collagen, type XXVII, alpha 1
chrX_+_151522352 1.011 ENSMUST00000148622.1
Phf8
PHD finger protein 8
chr11_-_69920892 1.008 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr15_-_85581809 0.996 ENSMUST00000023015.7
Wnt7b
wingless-related MMTV integration site 7B
chr18_+_34777008 0.971 ENSMUST00000043775.7
Kdm3b
KDM3B lysine (K)-specific demethylase 3B
chr5_-_115300912 0.945 ENSMUST00000112090.1
Dynll1
dynein light chain LC8-type 1
chr3_+_121426495 0.940 ENSMUST00000029773.8
Cnn3
calponin 3, acidic
chr11_-_70237852 0.890 ENSMUST00000108575.2
0610010K14Rik
RIKEN cDNA 0610010K14 gene
chr5_-_122989086 0.865 ENSMUST00000046073.9
Kdm2b
lysine (K)-specific demethylase 2B
chr14_+_62292475 0.862 ENSMUST00000166879.1
Rnaseh2b
ribonuclease H2, subunit B
chrM_+_9452 0.855 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr19_+_8941865 0.832 ENSMUST00000096240.2
Mta2
metastasis-associated gene family, member 2
chr7_+_127746775 0.831 ENSMUST00000033081.7
Fbxl19
F-box and leucine-rich repeat protein 19
chr5_-_115300957 0.829 ENSMUST00000009157.3
Dynll1
dynein light chain LC8-type 1
chr11_-_70237761 0.826 ENSMUST00000108576.3
0610010K14Rik
RIKEN cDNA 0610010K14 gene
chr16_+_20673264 0.814 ENSMUST00000154950.1
ENSMUST00000115461.1
Eif4g1

eukaryotic translation initiation factor 4, gamma 1

chr11_+_100619217 0.812 ENSMUST00000107376.1
Nkiras2
NFKB inhibitor interacting Ras-like protein 2
chr11_-_115536181 0.787 ENSMUST00000118155.1
ENSMUST00000153892.1
Sumo2

SMT3 suppressor of mif two 3 homolog 2 (yeast)

chr19_-_46039621 0.774 ENSMUST00000056931.7
Ldb1
LIM domain binding 1
chr6_+_17463826 0.748 ENSMUST00000140070.1
Met
met proto-oncogene
chr11_-_70237638 0.741 ENSMUST00000100950.3
0610010K14Rik
RIKEN cDNA 0610010K14 gene
chr11_+_77493408 0.726 ENSMUST00000037285.3
ENSMUST00000100812.3
Git1

G protein-coupled receptor kinase-interactor 1

chr15_+_102407144 0.724 ENSMUST00000169619.1
Sp1
trans-acting transcription factor 1
chr11_+_98795495 0.703 ENSMUST00000037915.2
Msl1
male-specific lethal 1 homolog (Drosophila)
chr11_+_97663366 0.664 ENSMUST00000044730.5
Mllt6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr5_-_122989260 0.657 ENSMUST00000118027.1
Kdm2b
lysine (K)-specific demethylase 2B
chr11_-_70237886 0.648 ENSMUST00000108577.1
ENSMUST00000108579.1
ENSMUST00000021181.6
ENSMUST00000108578.2
ENSMUST00000102569.3
0610010K14Rik




RIKEN cDNA 0610010K14 gene




chr2_-_156111954 0.642 ENSMUST00000142960.2
ENSMUST00000136296.2
ENSMUST00000059647.5
ENSMUST00000109604.2
ENSMUST00000138068.1
ENSMUST00000128499.1
Cpne1

Rbm12



copine I

RNA binding motif protein 12



chr14_+_25607797 0.630 ENSMUST00000160229.1
Zmiz1
zinc finger, MIZ-type containing 1
chr15_+_102406143 0.573 ENSMUST00000170884.1
ENSMUST00000165924.1
ENSMUST00000163709.1
ENSMUST00000001326.6
Sp1



trans-acting transcription factor 1



chr8_-_88362154 0.572 ENSMUST00000034085.7
Brd7
bromodomain containing 7
chr1_-_168432270 0.559 ENSMUST00000072863.4
Pbx1
pre B cell leukemia homeobox 1
chr7_-_4812351 0.547 ENSMUST00000079496.7
Ube2s
ubiquitin-conjugating enzyme E2S
chr9_+_108306205 0.536 ENSMUST00000007959.8
Rhoa
ras homolog gene family, member A
chr10_-_7663245 0.528 ENSMUST00000163085.1
ENSMUST00000159917.1
Pcmt1

protein-L-isoaspartate (D-aspartate) O-methyltransferase 1

chr4_-_41695935 0.521 ENSMUST00000145379.1
Cntfr
ciliary neurotrophic factor receptor
chr1_-_168431695 0.494 ENSMUST00000176790.1
Pbx1
pre B cell leukemia homeobox 1
chr11_-_115535804 0.484 ENSMUST00000117589.1
ENSMUST00000121185.1
Sumo2

SMT3 suppressor of mif two 3 homolog 2 (yeast)

chr11_-_52000748 0.466 ENSMUST00000109086.1
Ube2b
ubiquitin-conjugating enzyme E2B
chr7_+_127485221 0.397 ENSMUST00000048896.6
Fbrs
fibrosin
chr2_-_114052804 0.393 ENSMUST00000090269.6
Actc1
actin, alpha, cardiac muscle 1
chr9_-_110117379 0.390 ENSMUST00000111991.2
ENSMUST00000149199.1
ENSMUST00000035056.7
ENSMUST00000148287.1
ENSMUST00000127744.1
Dhx30




DEAH (Asp-Glu-Ala-His) box polypeptide 30




chr18_-_47368446 0.359 ENSMUST00000076043.6
ENSMUST00000135790.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chrX_-_23365044 0.358 ENSMUST00000115313.1
Klhl13
kelch-like 13
chr13_+_119428583 0.346 ENSMUST00000109203.2
Paip1
polyadenylate binding protein-interacting protein 1
chr8_+_70863127 0.340 ENSMUST00000050921.2
A230052G05Rik
RIKEN cDNA A230052G05 gene
chrX_-_94542037 0.336 ENSMUST00000026142.7
Maged1
melanoma antigen, family D, 1
chr11_-_96065350 0.324 ENSMUST00000100528.4
Ube2z
ubiquitin-conjugating enzyme E2Z (putative)
chrX_+_101254528 0.281 ENSMUST00000062000.4
Foxo4
forkhead box O4
chr11_-_100619576 0.264 ENSMUST00000155152.1
Dnajc7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr13_+_119428888 0.256 ENSMUST00000026520.7
Paip1
polyadenylate binding protein-interacting protein 1
chr17_-_34031684 0.255 ENSMUST00000169397.1
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr7_-_75308373 0.223 ENSMUST00000085164.5
Sv2b
synaptic vesicle glycoprotein 2 b
chr11_+_5861886 0.194 ENSMUST00000102923.3
Aebp1
AE binding protein 1
chr5_+_110135823 0.190 ENSMUST00000112519.2
ENSMUST00000014812.8
Chfr

checkpoint with forkhead and ring finger domains

chr7_+_25282179 0.176 ENSMUST00000163320.1
ENSMUST00000005578.6
Cic

capicua homolog (Drosophila)

chr3_+_89245952 0.175 ENSMUST00000040888.5
Krtcap2
keratinocyte associated protein 2
chr2_-_152830615 0.170 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
Bcl2l1



BCL2-like 1



chr9_+_31280525 0.161 ENSMUST00000117389.1
Prdm10
PR domain containing 10
chr4_+_137993445 0.152 ENSMUST00000105831.2
ENSMUST00000084214.5
Eif4g3

eukaryotic translation initiation factor 4 gamma, 3

chr2_-_152831112 0.148 ENSMUST00000128172.1
Bcl2l1
BCL2-like 1
chr6_+_17463927 0.136 ENSMUST00000115442.1
Met
met proto-oncogene
chr11_+_77982710 0.126 ENSMUST00000108360.1
ENSMUST00000049167.7
Phf12

PHD finger protein 12

chr11_-_52000432 0.118 ENSMUST00000020657.6
Ube2b
ubiquitin-conjugating enzyme E2B
chr4_+_86053887 0.098 ENSMUST00000107178.2
ENSMUST00000048885.5
ENSMUST00000141889.1
ENSMUST00000120678.1
Adamtsl1



ADAMTS-like 1



chr7_-_126200474 0.096 ENSMUST00000168189.1
Xpo6
exportin 6
chr4_+_118428078 0.089 ENSMUST00000006557.6
ENSMUST00000167636.1
ENSMUST00000102673.4
Elovl1


elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1


chr3_-_94582548 0.085 ENSMUST00000107283.1
Snx27
sorting nexin family member 27
chr17_+_86963279 0.084 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr7_+_3332918 0.069 ENSMUST00000092891.4
Cacng7
calcium channel, voltage-dependent, gamma subunit 7
chr6_+_17463749 0.069 ENSMUST00000115443.1
Met
met proto-oncogene
chr2_-_152831665 0.052 ENSMUST00000156688.1
ENSMUST00000007803.5
Bcl2l1

BCL2-like 1

chr17_-_34031644 0.041 ENSMUST00000171872.1
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr7_+_16401187 0.041 ENSMUST00000098789.3
Zc3h4
zinc finger CCCH-type containing 4
chr9_+_108460518 0.035 ENSMUST00000061209.5
Ccdc71
coiled-coil domain containing 71
chrX_-_38564519 0.032 ENSMUST00000016681.8
Cul4b
cullin 4B
chr8_-_87472576 0.028 ENSMUST00000034076.8
Cbln1
cerebellin 1 precursor protein
chr6_+_95117740 0.018 ENSMUST00000032107.7
ENSMUST00000119582.1
Kbtbd8

kelch repeat and BTB (POZ) domain containing 8

chr17_-_23745829 0.004 ENSMUST00000046525.8
Kremen2
kringle containing transmembrane protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.4 GO:0042414 epinephrine metabolic process(GO:0042414)
1.0 9.1 GO:0010587 miRNA catabolic process(GO:0010587)
1.0 3.9 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.8 4.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.8 2.3 GO:0070172 oculomotor nerve development(GO:0021557) positive regulation of tooth mineralization(GO:0070172)
0.6 2.9 GO:0048133 NK T cell differentiation(GO:0001865) germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728)
0.6 1.7 GO:0003032 detection of oxygen(GO:0003032)
0.5 2.2 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.5 1.5 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.4 1.7 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.4 1.2 GO:0071336 lung growth(GO:0060437) positive regulation of fat cell proliferation(GO:0070346) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.4 1.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.3 2.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.3 1.0 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.3 8.8 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.3 1.0 GO:0072070 establishment or maintenance of polarity of embryonic epithelium(GO:0016332) trachea cartilage morphogenesis(GO:0060535) loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.3 1.0 GO:0072718 response to cisplatin(GO:0072718)
0.3 1.5 GO:0021993 initiation of neural tube closure(GO:0021993)
0.3 5.0 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.3 1.0 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.2 1.6 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.2 4.1 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 1.8 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.2 1.2 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.2 1.6 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601) regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.2 0.6 GO:0033128 positive regulation of reciprocal meiotic recombination(GO:0010845) negative regulation of histone phosphorylation(GO:0033128)
0.2 0.8 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.2 1.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353) hydrogen sulfide biosynthetic process(GO:0070814)
0.2 0.5 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.2 0.5 GO:0003100 angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) regulation of systemic arterial blood pressure by endothelin(GO:0003100) beta selection(GO:0043366)
0.2 1.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 0.5 GO:0003360 brainstem development(GO:0003360)
0.2 1.0 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 5.0 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 1.8 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 2.6 GO:0051602 response to electrical stimulus(GO:0051602)
0.1 1.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.7 GO:0001771 immunological synapse formation(GO:0001771)
0.1 0.4 GO:0046898 response to cycloheximide(GO:0046898)
0.1 0.6 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.4 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 0.4 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.9 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.3 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 1.1 GO:0002467 germinal center formation(GO:0002467)
0.1 1.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.1 0.2 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 1.5 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.9 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 1.9 GO:0060325 face morphogenesis(GO:0060325)
0.0 2.5 GO:0002209 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0 0.7 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.9 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 1.4 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.5 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 1.3 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.6 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 0.3 GO:0090190 positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.8 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 1.2 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 1.2 GO:0098792 xenophagy(GO:0098792)
0.0 1.3 GO:0008203 cholesterol metabolic process(GO:0008203)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.3 3.1 GO:0016589 NURF complex(GO:0016589)
0.2 1.6 GO:0042382 paraspeckles(GO:0042382)
0.2 4.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 0.5 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.2 2.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.2 1.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 9.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.9 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.7 GO:0072487 MSL complex(GO:0072487)
0.1 1.0 GO:0005642 annulate lamellae(GO:0005642)
0.1 1.8 GO:0001650 fibrillar center(GO:0001650)
0.1 1.4 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 0.6 GO:0033503 HULC complex(GO:0033503)
0.1 1.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 4.4 GO:0016605 PML body(GO:0016605)
0.0 0.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.5 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.7 GO:0016235 aggresome(GO:0016235)
0.0 2.1 GO:0072562 blood microparticle(GO:0072562)
0.0 8.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.5 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.6 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.5 GO:0016607 nuclear speck(GO:0016607)
0.0 0.9 GO:0070469 respiratory chain(GO:0070469)
0.0 1.3 GO:0032993 protein-DNA complex(GO:0032993)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.4 GO:0035240 dopamine binding(GO:0035240)
0.6 1.7 GO:0005534 galactose binding(GO:0005534)
0.5 9.1 GO:0035198 miRNA binding(GO:0035198)
0.4 1.5 GO:0050700 CARD domain binding(GO:0050700)
0.4 1.8 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.3 1.0 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.3 2.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.3 1.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.3 1.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.2 1.0 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 1.0 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 2.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 4.1 GO:0070410 co-SMAD binding(GO:0070410)
0.1 1.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 1.1 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.6 GO:0008494 translation activator activity(GO:0008494)
0.1 2.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.2 GO:0070700 BMP receptor binding(GO:0070700)
0.1 1.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 1.3 GO:0031386 protein tag(GO:0031386)
0.1 0.5 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 2.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 2.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.3 GO:0032452 histone demethylase activity(GO:0032452)
0.1 2.1 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.5 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 1.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 1.0 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.0 5.6 GO:0001047 core promoter binding(GO:0001047)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 19.5 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 1.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0003713 transcription coactivator activity(GO:0003713)