Motif ID: Gmeb1

Z-value: 0.571


Transcription factors associated with Gmeb1:

Gene SymbolEntrez IDGene Name
Gmeb1 ENSMUSG00000028901.7 Gmeb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gmeb1mm10_v2_chr4_-_132261596_1322616220.354.9e-02Click!


Activity profile for motif Gmeb1.

activity profile for motif Gmeb1


Sorted Z-values histogram for motif Gmeb1

Sorted Z-values for motif Gmeb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gmeb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 87 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_23679363 2.863 ENSMUST00000024699.2
 Cldn6
claudin 6
chr1_+_175880775 2.204 ENSMUST00000039725.6
 Exo1
exonuclease 1
chr6_+_113531675 2.119 ENSMUST00000036340.5
ENSMUST00000101051.2
 Fancd2

Fanconi anemia, complementation group D2

chr13_-_53473074 2.026 ENSMUST00000021922.8
 Msx2
msh homeobox 2
chr2_-_157007015 1.517 ENSMUST00000146413.1
 Dsn1
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr2_-_157007039 1.459 ENSMUST00000103129.2
ENSMUST00000103130.1
 Dsn1

DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)

chr7_-_19310035 1.431 ENSMUST00000003640.2
 Fosb
FBJ osteosarcoma oncogene B
chr11_+_86544982 1.417 ENSMUST00000108030.2
ENSMUST00000020821.3
ENSMUST00000069503.6
ENSMUST00000167178.2
 Tubd1



tubulin, delta 1



chr8_-_123949201 1.368 ENSMUST00000044795.7
 Nup133
nucleoporin 133
chrX_+_112311334 1.231 ENSMUST00000026599.3
ENSMUST00000113415.1
 Apool

apolipoprotein O-like

chr11_-_100822525 1.222 ENSMUST00000107358.2
 Stat5b
signal transducer and activator of transcription 5B
chr3_+_40800054 1.184 ENSMUST00000168287.1
 Plk4
polo-like kinase 4
chr3_-_138143352 1.145 ENSMUST00000098580.2
 Mttp
microsomal triglyceride transfer protein
chr17_+_84511832 1.109 ENSMUST00000047206.5
 Plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr3_+_40800013 1.026 ENSMUST00000026858.5
ENSMUST00000170825.1
 Plk4

polo-like kinase 4

chr8_-_45333189 1.017 ENSMUST00000095328.4
 Cyp4v3
cytochrome P450, family 4, subfamily v, polypeptide 3
chr4_-_135353126 1.009 ENSMUST00000030613.4
ENSMUST00000131373.1
 Srrm1

serine/arginine repetitive matrix 1

chr19_+_43612299 0.926 ENSMUST00000057178.9
 Nkx2-3
NK2 homeobox 3
chr11_+_53770458 0.925 ENSMUST00000138913.1
ENSMUST00000123376.1
ENSMUST00000019043.6
ENSMUST00000133291.1
 Irf1



interferon regulatory factor 1



chr15_+_99074968 0.914 ENSMUST00000039665.6
 Troap
trophinin associated protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.9 GO:0045216 cell-cell junction organization(GO:0045216)
0.4 2.2 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.2 2.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.3 2.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.7 2.0 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.1 1.6 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.5 1.5 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.2 1.4 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 1.4 GO:0071277 cellular response to calcium ion(GO:0071277)
0.4 1.2 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.1 1.2 GO:0042407 cristae formation(GO:0042407)
0.0 1.2 GO:0034605 cellular response to heat(GO:0034605)
0.2 1.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 1.1 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.1 1.0 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.0 1.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.3 0.9 GO:2000564 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.2 0.9 GO:0002317 plasma cell differentiation(GO:0002317)
0.3 0.8 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.1 0.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.0 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 2.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.3 2.2 GO:0098536 deuterosome(GO:0098536)
0.0 2.1 GO:0000793 condensed chromosome(GO:0000793)
0.1 1.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.2 GO:0061617 MICOS complex(GO:0061617)
0.1 1.1 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 1.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.8 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.7 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 0.6 GO:0071942 XPC complex(GO:0071942)
0.1 0.6 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.3 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.4 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.2 2.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.6 2.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297) double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 1.6 GO:0000049 tRNA binding(GO:0000049)
0.5 1.5 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.1 1.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 1.0 GO:0032564 dATP binding(GO:0032564)
0.1 1.0 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.0 1.0 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 0.8 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 0.8 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.8 GO:0071949 FAD binding(GO:0071949)
0.0 0.8 GO:0043236 laminin binding(GO:0043236)
0.2 0.7 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.6 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.6 GO:0003684 damaged DNA binding(GO:0003684)