Motif ID: Gmeb2

Z-value: 0.456


Transcription factors associated with Gmeb2:

Gene SymbolEntrez IDGene Name
Gmeb2 ENSMUSG00000038705.7 Gmeb2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gmeb2mm10_v2_chr2_-_181288016_1812880410.057.9e-01Click!


Activity profile for motif Gmeb2.

activity profile for motif Gmeb2


Sorted Z-values histogram for motif Gmeb2

Sorted Z-values for motif Gmeb2



Network of associatons between targets according to the STRING database.



First level regulatory network of Gmeb2

PNG image of the network

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Top targets:


Showing 1 to 20 of 199 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_78544345 1.888 ENSMUST00000053239.2
Sstr3
somatostatin receptor 3
chr7_-_119896285 0.885 ENSMUST00000106519.1
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr3_-_89089955 0.775 ENSMUST00000166687.1
Rusc1
RUN and SH3 domain containing 1
chr6_-_29212240 0.692 ENSMUST00000160878.1
ENSMUST00000078155.5
Impdh1

inosine 5'-phosphate dehydrogenase 1

chr5_-_31291026 0.652 ENSMUST00000041565.7
Ift172
intraflagellar transport 172
chr1_+_52008210 0.591 ENSMUST00000027277.5
Stat4
signal transducer and activator of transcription 4
chr7_+_119896292 0.578 ENSMUST00000106517.1
Lyrm1
LYR motif containing 1
chr7_-_83884289 0.566 ENSMUST00000094216.3
Mesdc1
mesoderm development candidate 1
chr7_-_4546567 0.549 ENSMUST00000065957.5
Syt5
synaptotagmin V
chr7_+_66839752 0.547 ENSMUST00000107478.1
Adamts17
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr7_+_66839726 0.545 ENSMUST00000098382.3
Adamts17
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr9_+_107296843 0.490 ENSMUST00000167072.1
Cish
cytokine inducible SH2-containing protein
chr4_-_4138432 0.475 ENSMUST00000070375.7
Penk
preproenkephalin
chr8_+_95320440 0.464 ENSMUST00000162294.1
Tepp
testis, prostate and placenta expressed
chr11_+_83302817 0.462 ENSMUST00000142680.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chrX_+_150588223 0.458 ENSMUST00000153221.1
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr7_+_119895836 0.455 ENSMUST00000106518.1
ENSMUST00000054440.3
Lyrm1

LYR motif containing 1

chr12_+_73964481 0.453 ENSMUST00000021532.4
Snapc1
small nuclear RNA activating complex, polypeptide 1
chr5_-_110343009 0.450 ENSMUST00000058016.9
ENSMUST00000112478.3
P2rx2

purinergic receptor P2X, ligand-gated ion channel, 2

chr2_-_37703845 0.445 ENSMUST00000155237.1
Strbp
spermatid perinuclear RNA binding protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 1.4 GO:0010225 response to UV-C(GO:0010225)
0.0 0.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.3 0.8 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.0 0.8 GO:0035904 aorta development(GO:0035904)
0.1 0.7 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.1 0.7 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.7 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.7 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.6 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.6 GO:0046033 AMP metabolic process(GO:0046033)
0.1 0.5 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.5 GO:0048791 synaptic vesicle endocytosis(GO:0048488) calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.4 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 0.4 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.4 GO:0014848 urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848) peristalsis(GO:0030432)
0.0 0.4 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.3 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.9 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.2 0.7 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.7 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.6 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.2 0.5 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.4 GO:0045120 telomerase holoenzyme complex(GO:0005697) pronucleus(GO:0045120)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.3 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 1.9 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 1.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.3 GO:0030276 clathrin binding(GO:0030276)
0.3 0.8 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.1 0.8 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 0.7 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 0.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.7 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.7 GO:0046870 cadmium ion binding(GO:0046870)
0.2 0.6 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.4 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 0.4 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 0.3 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.1 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.3 GO:0005047 signal recognition particle binding(GO:0005047) endoplasmic reticulum signal peptide binding(GO:0030942)