Motif ID: Gsc2_Dmbx1

Z-value: 0.398

Transcription factors associated with Gsc2_Dmbx1:

Gene SymbolEntrez IDGene Name
Dmbx1 ENSMUSG00000028707.9 Dmbx1
Gsc2 ENSMUSG00000022738.6 Gsc2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dmbx1mm10_v2_chr4_-_115939923_1159399280.144.3e-01Click!


Activity profile for motif Gsc2_Dmbx1.

activity profile for motif Gsc2_Dmbx1


Sorted Z-values histogram for motif Gsc2_Dmbx1

Sorted Z-values for motif Gsc2_Dmbx1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gsc2_Dmbx1

PNG image of the network

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Top targets:


Showing 1 to 20 of 99 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_137766474 2.690 ENSMUST00000139951.1
 Alpl
alkaline phosphatase, liver/bone/kidney
chr11_-_52282564 1.227 ENSMUST00000086844.3
 Tcf7
transcription factor 7, T cell specific
chr17_+_35861318 0.940 ENSMUST00000074259.8
ENSMUST00000174873.1
 Nrm

nurim (nuclear envelope membrane protein)

chr2_+_102658640 0.880 ENSMUST00000080210.3
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr2_+_102659213 0.824 ENSMUST00000111213.1
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr14_-_31640878 0.808 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
 Hacl1


2-hydroxyacyl-CoA lyase 1


chr4_+_154960915 0.805 ENSMUST00000049621.6
 Hes5
hairy and enhancer of split 5 (Drosophila)
chr9_+_50617516 0.800 ENSMUST00000141366.1
 Pih1d2
PIH1 domain containing 2
chr2_+_91259822 0.800 ENSMUST00000138470.1
 Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr2_-_24049389 0.707 ENSMUST00000051416.5
 Hnmt
histamine N-methyltransferase
chr17_+_35861343 0.697 ENSMUST00000172931.1
 Nrm
nurim (nuclear envelope membrane protein)
chr17_-_58991343 0.685 ENSMUST00000025064.7
 2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr5_+_77265454 0.677 ENSMUST00000080359.5
 Rest
RE1-silencing transcription factor
chr1_+_178187417 0.624 ENSMUST00000161075.1
ENSMUST00000027783.7
 Desi2

desumoylating isopeptidase 2

chr1_+_44551483 0.618 ENSMUST00000074525.3
 Gulp1
GULP, engulfment adaptor PTB domain containing 1
chr8_+_78509319 0.566 ENSMUST00000034111.8
 Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr11_-_90687572 0.560 ENSMUST00000107869.2
ENSMUST00000154599.1
ENSMUST00000107868.1
ENSMUST00000020849.2
 Tom1l1



target of myb1-like 1 (chicken)



chrM_+_8600 0.505 ENSMUST00000082409.1
 mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr11_+_78322965 0.501 ENSMUST00000017534.8
 Aldoc
aldolase C, fructose-bisphosphate
chr7_-_105752193 0.473 ENSMUST00000033184.4
 Tpp1
tripeptidyl peptidase I

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.7 GO:0046677 response to antibiotic(GO:0046677)
0.3 1.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.2 1.2 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0 1.0 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.3 0.8 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.2 0.8 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.2 0.8 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 0.7 GO:1902524 negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.2 0.7 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.0 0.6 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.5 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.4 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 0.4 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533)
0.1 0.4 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.7 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 1.7 GO:0030673 axolemma(GO:0030673)
0.1 1.6 GO:0005652 nuclear lamina(GO:0005652)
0.0 1.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.4 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.7 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.4 1.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.8 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.8 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.8 GO:0030332 cyclin binding(GO:0030332)
0.1 0.7 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.6 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.5 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 0.4 GO:0031432 titin binding(GO:0031432)
0.0 0.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0015168 glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.2 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)