Motif ID: Gsc2_Dmbx1

Z-value: 0.398

Transcription factors associated with Gsc2_Dmbx1:

Gene SymbolEntrez IDGene Name
Dmbx1 ENSMUSG00000028707.9 Dmbx1
Gsc2 ENSMUSG00000022738.6 Gsc2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dmbx1mm10_v2_chr4_-_115939923_1159399280.144.3e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gsc2_Dmbx1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_137766474 2.690 ENSMUST00000139951.1
Alpl
alkaline phosphatase, liver/bone/kidney
chr11_-_52282564 1.227 ENSMUST00000086844.3
Tcf7
transcription factor 7, T cell specific
chr17_+_35861318 0.940 ENSMUST00000074259.8
ENSMUST00000174873.1
Nrm

nurim (nuclear envelope membrane protein)

chr2_+_102658640 0.880 ENSMUST00000080210.3
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr2_+_102659213 0.824 ENSMUST00000111213.1
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr14_-_31640878 0.808 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
Hacl1


2-hydroxyacyl-CoA lyase 1


chr4_+_154960915 0.805 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr9_+_50617516 0.800 ENSMUST00000141366.1
Pih1d2
PIH1 domain containing 2
chr2_+_91259822 0.800 ENSMUST00000138470.1
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr2_-_24049389 0.707 ENSMUST00000051416.5
Hnmt
histamine N-methyltransferase
chr17_+_35861343 0.697 ENSMUST00000172931.1
Nrm
nurim (nuclear envelope membrane protein)
chr17_-_58991343 0.685 ENSMUST00000025064.7
2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr5_+_77265454 0.677 ENSMUST00000080359.5
Rest
RE1-silencing transcription factor
chr1_+_178187417 0.624 ENSMUST00000161075.1
ENSMUST00000027783.7
Desi2

desumoylating isopeptidase 2

chr1_+_44551483 0.618 ENSMUST00000074525.3
Gulp1
GULP, engulfment adaptor PTB domain containing 1
chr8_+_78509319 0.566 ENSMUST00000034111.8
Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr11_-_90687572 0.560 ENSMUST00000107869.2
ENSMUST00000154599.1
ENSMUST00000107868.1
ENSMUST00000020849.2
Tom1l1



target of myb1-like 1 (chicken)



chrM_+_8600 0.505 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr11_+_78322965 0.501 ENSMUST00000017534.8
Aldoc
aldolase C, fructose-bisphosphate
chr7_-_105752193 0.473 ENSMUST00000033184.4
Tpp1
tripeptidyl peptidase I
chr5_+_3344194 0.463 ENSMUST00000042410.4
Cdk6
cyclin-dependent kinase 6
chr7_-_133015248 0.443 ENSMUST00000169570.1
Ctbp2
C-terminal binding protein 2
chrX_-_23285532 0.437 ENSMUST00000115319.2
Klhl13
kelch-like 13
chr1_+_178187721 0.430 ENSMUST00000159284.1
Desi2
desumoylating isopeptidase 2
chr2_+_120476911 0.421 ENSMUST00000110716.1
ENSMUST00000028748.6
ENSMUST00000090028.5
ENSMUST00000110719.2
Capn3



calpain 3



chr14_-_118052235 0.409 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr19_-_12765447 0.383 ENSMUST00000112933.1
Cntf
ciliary neurotrophic factor
chr1_+_44551650 0.379 ENSMUST00000160854.1
Gulp1
GULP, engulfment adaptor PTB domain containing 1
chr16_-_35490873 0.378 ENSMUST00000023550.7
Pdia5
protein disulfide isomerase associated 5
chr13_+_3361029 0.371 ENSMUST00000179981.1
Gm16505
predicted gene 16505
chr10_-_22149270 0.370 ENSMUST00000179054.1
ENSMUST00000069372.6
E030030I06Rik

RIKEN cDNA E030030I06 gene

chr2_-_51972990 0.342 ENSMUST00000145481.1
ENSMUST00000112705.2
Nmi

N-myc (and STAT) interactor

chr2_-_73486456 0.336 ENSMUST00000141264.1
Wipf1
WAS/WASL interacting protein family, member 1
chr11_-_68973840 0.336 ENSMUST00000038644.4
Rangrf
RAN guanine nucleotide release factor
chr5_+_3343893 0.335 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr2_-_51973219 0.325 ENSMUST00000028314.2
Nmi
N-myc (and STAT) interactor
chr2_-_121456693 0.323 ENSMUST00000110613.2
ENSMUST00000056312.3
Serinc4

serine incorporator 4

chr3_+_28781305 0.323 ENSMUST00000060500.7
Eif5a2
eukaryotic translation initiation factor 5A2
chr1_+_12692430 0.318 ENSMUST00000180062.1
ENSMUST00000177608.1
Sulf1

sulfatase 1

chr3_-_8964037 0.318 ENSMUST00000091354.5
ENSMUST00000094381.4
Tpd52

tumor protein D52

chr14_+_99298652 0.309 ENSMUST00000005279.6
Klf5
Kruppel-like factor 5
chr18_-_12305638 0.304 ENSMUST00000122408.1
ENSMUST00000118525.1
ENSMUST00000142066.1
Ankrd29


ankyrin repeat domain 29


chrX_+_134585644 0.292 ENSMUST00000113211.1
Rpl36a
ribosomal protein L36A
chr2_+_164562579 0.285 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
Wfdc2


WAP four-disulfide core domain 2


chr1_-_155232710 0.270 ENSMUST00000035914.3
BC034090
cDNA sequence BC034090
chr4_-_133968611 0.267 ENSMUST00000102552.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr13_-_113618549 0.265 ENSMUST00000109241.3
Snx18
sorting nexin 18
chr10_+_128225830 0.251 ENSMUST00000026455.7
Mip
major intrinsic protein of eye lens fiber
chr5_-_96161990 0.249 ENSMUST00000155901.1
Cnot6l
CCR4-NOT transcription complex, subunit 6-like
chr5_+_149184678 0.242 ENSMUST00000139474.1
ENSMUST00000117878.1
Uspl1

ubiquitin specific peptidase like 1

chr19_+_36083696 0.215 ENSMUST00000025714.7
Rpp30
ribonuclease P/MRP 30 subunit
chr7_-_127725616 0.215 ENSMUST00000076091.2
Ctf2
cardiotrophin 2
chr19_-_47919269 0.204 ENSMUST00000095998.5
Itprip
inositol 1,4,5-triphosphate receptor interacting protein
chr19_+_8617991 0.201 ENSMUST00000010250.2
Slc22a6
solute carrier family 22 (organic anion transporter), member 6
chr13_-_23562369 0.195 ENSMUST00000105107.1
Hist1h3e
histone cluster 1, H3e
chrX_+_169879596 0.193 ENSMUST00000112105.1
ENSMUST00000078947.5
Mid1

midline 1

chr13_+_23752267 0.189 ENSMUST00000091703.2
Hist1h3b
histone cluster 1, H3b
chr10_+_21993890 0.181 ENSMUST00000092673.4
Sgk1
serum/glucocorticoid regulated kinase 1
chr6_+_3993776 0.175 ENSMUST00000031673.5
Gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr19_+_43752996 0.170 ENSMUST00000026199.7
ENSMUST00000112047.3
ENSMUST00000153295.1
Cutc


cutC copper transporter homolog (E.coli)


chr1_-_168431695 0.163 ENSMUST00000176790.1
Pbx1
pre B cell leukemia homeobox 1
chr13_-_21783391 0.159 ENSMUST00000099704.3
Hist1h3i
histone cluster 1, H3i
chr7_-_15879844 0.147 ENSMUST00000172758.1
ENSMUST00000044434.6
Crx

cone-rod homeobox containing gene

chr13_-_97747373 0.135 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr10_+_90576872 0.132 ENSMUST00000182550.1
ENSMUST00000099364.5
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr11_+_23256566 0.130 ENSMUST00000136235.1
Xpo1
exportin 1, CRM1 homolog (yeast)
chr4_-_141053660 0.127 ENSMUST00000040222.7
Crocc
ciliary rootlet coiled-coil, rootletin
chr18_+_46597698 0.123 ENSMUST00000078079.3
ENSMUST00000168382.1
Eif1a

eukaryotic translation initiation factor 1A

chr5_-_134456702 0.114 ENSMUST00000073161.5
ENSMUST00000171794.2
ENSMUST00000111245.2
ENSMUST00000100654.3
ENSMUST00000167084.2
ENSMUST00000100652.3
ENSMUST00000100650.3
ENSMUST00000074114.5
Gtf2ird1







general transcription factor II I repeat domain-containing 1







chrM_+_7759 0.110 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr2_-_9883993 0.108 ENSMUST00000114915.2
9230102O04Rik
RIKEN cDNA 9230102O04 gene
chr2_-_30093642 0.104 ENSMUST00000102865.4
Zdhhc12
zinc finger, DHHC domain containing 12
chr8_-_60954726 0.100 ENSMUST00000110302.1
Clcn3
chloride channel 3
chr4_-_139833524 0.100 ENSMUST00000030508.7
Pax7
paired box gene 7
chr15_-_74734313 0.095 ENSMUST00000023260.3
Lypd2
Ly6/Plaur domain containing 2
chr9_-_50617228 0.089 ENSMUST00000147671.1
ENSMUST00000145139.1
ENSMUST00000155435.1
AU019823


expressed sequence AU019823


chr16_-_76403673 0.086 ENSMUST00000052867.7
Gm9843
predicted gene 9843
chr8_-_113848615 0.085 ENSMUST00000093113.4
Adamts18
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
chr2_-_30093607 0.084 ENSMUST00000081838.6
Zdhhc12
zinc finger, DHHC domain containing 12
chr10_+_80930071 0.078 ENSMUST00000015456.8
Gadd45b
growth arrest and DNA-damage-inducible 45 beta
chr11_+_98026695 0.076 ENSMUST00000092425.4
Rpl19
ribosomal protein L19
chr19_+_46056539 0.064 ENSMUST00000111899.1
ENSMUST00000099392.3
ENSMUST00000062322.4
Pprc1


peroxisome proliferative activated receptor, gamma, coactivator-related 1


chr4_+_102589687 0.059 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr4_-_141053704 0.059 ENSMUST00000102491.3
Crocc
ciliary rootlet coiled-coil, rootletin
chr11_+_19924354 0.044 ENSMUST00000093299.6
Spred2
sprouty-related, EVH1 domain containing 2
chr10_+_80292453 0.035 ENSMUST00000068408.7
ENSMUST00000062674.6
Rps15

ribosomal protein S15

chr14_-_54617993 0.032 ENSMUST00000022803.4
Psmb5
proteasome (prosome, macropain) subunit, beta type 5
chr11_+_23256001 0.029 ENSMUST00000020538.6
ENSMUST00000109551.1
ENSMUST00000102870.1
ENSMUST00000102869.1
Xpo1



exportin 1, CRM1 homolog (yeast)



chr9_-_60838200 0.028 ENSMUST00000063858.7
Gm9869
predicted gene 9869
chr11_-_103954015 0.027 ENSMUST00000103075.4
Nsf
N-ethylmaleimide sensitive fusion protein
chr16_-_4213404 0.024 ENSMUST00000023165.6
Crebbp
CREB binding protein
chr13_+_75089826 0.020 ENSMUST00000022075.4
Pcsk1
proprotein convertase subtilisin/kexin type 1
chr7_-_80403315 0.015 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr17_-_35164891 0.015 ENSMUST00000025253.5
Prrc2a
proline-rich coiled-coil 2A
chr1_-_168431896 0.014 ENSMUST00000176540.1
Pbx1
pre B cell leukemia homeobox 1
chr2_+_121456963 0.014 ENSMUST00000126764.1
Hypk
huntingtin interacting protein K
chr19_-_43752924 0.013 ENSMUST00000045562.5
Cox15
cytochrome c oxidase assembly protein 15
chr1_-_92473801 0.009 ENSMUST00000027478.6
Ndufa10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10
chr7_-_133123770 0.005 ENSMUST00000164896.1
ENSMUST00000171968.1
Ctbp2

C-terminal binding protein 2


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.3 0.8 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.2 0.7 GO:1902524 negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.2 0.8 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.2 0.7 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.2 0.8 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.2 1.2 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.1 0.4 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 0.4 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533)
0.1 2.7 GO:0046677 response to antibiotic(GO:0046677)
0.1 0.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.4 GO:0006570 tyrosine metabolic process(GO:0006570)
0.1 0.2 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.2 GO:0030576 Cajal body organization(GO:0030576)
0.1 0.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.3 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388) synaptic vesicle lumen acidification(GO:0097401)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.3 GO:2000010 positive regulation of protein localization to cell surface(GO:2000010)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 1.0 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.6 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.5 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.3 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.3 GO:0040034 regulation of development, heterochronic(GO:0040034)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 0.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 1.6 GO:0005652 nuclear lamina(GO:0005652)
0.1 1.7 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 1.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.4 1.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.5 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 0.8 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.6 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.2 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.1 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.7 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.8 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.4 GO:0031432 titin binding(GO:0031432)
0.0 0.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0015168 glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.0 0.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.8 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)