Motif ID: Gsx2_Hoxd3_Vax1

Z-value: 0.721

Transcription factors associated with Gsx2_Hoxd3_Vax1:

Gene SymbolEntrez IDGene Name
Gsx2 ENSMUSG00000035946.6 Gsx2
Hoxd3 ENSMUSG00000079277.3 Hoxd3
Vax1 ENSMUSG00000006270.6 Vax1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gsx2mm10_v2_chr5_+_75075464_750756010.411.7e-02Click!
Vax1mm10_v2_chr19_-_59170978_591709780.354.6e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gsx2_Hoxd3_Vax1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_48662740 6.388 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr2_+_109917639 6.206 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr2_-_168767136 5.836 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr9_+_119063429 4.902 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr2_-_168767029 4.284 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr15_+_25773985 3.568 ENSMUST00000125667.1
Myo10
myosin X
chr9_-_90255927 3.292 ENSMUST00000144646.1
Tbc1d2b
TBC1 domain family, member 2B
chr13_-_53473074 3.249 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr18_+_56432116 2.433 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr19_+_55895508 2.407 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chrX_+_150547375 2.291 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr4_+_8690399 2.271 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr6_-_23248264 2.142 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr3_+_159839729 2.082 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chr6_-_34317442 1.819 ENSMUST00000154655.1
ENSMUST00000102980.4
Akr1b3

aldo-keto reductase family 1, member B3 (aldose reductase)

chr10_+_128337761 1.819 ENSMUST00000005826.7
Cs
citrate synthase
chr13_+_51408618 1.785 ENSMUST00000087978.3
S1pr3
sphingosine-1-phosphate receptor 3
chr2_+_120476911 1.761 ENSMUST00000110716.1
ENSMUST00000028748.6
ENSMUST00000090028.5
ENSMUST00000110719.2
Capn3



calpain 3



chr11_+_59306920 1.627 ENSMUST00000000128.3
ENSMUST00000108783.3
Wnt9a

wingless-type MMTV integration site 9A

chr17_-_70853482 1.615 ENSMUST00000118283.1
Tgif1
TGFB-induced factor homeobox 1
chr13_-_102905740 1.531 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr5_+_138187485 1.529 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr13_-_102906046 1.464 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr14_+_48446128 1.371 ENSMUST00000124720.1
Tmem260
transmembrane protein 260
chr2_-_28916412 1.345 ENSMUST00000050776.2
ENSMUST00000113849.1
Barhl1

BarH-like 1 (Drosophila)

chr12_-_55014329 1.342 ENSMUST00000172875.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr11_+_114851507 1.308 ENSMUST00000177952.1
Gprc5c
G protein-coupled receptor, family C, group 5, member C
chr2_+_36230426 1.301 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr10_+_128083273 1.236 ENSMUST00000026459.5
Atp5b
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr12_+_112760652 1.208 ENSMUST00000063888.3
Pld4
phospholipase D family, member 4
chr2_-_120154600 1.170 ENSMUST00000028755.7
Ehd4
EH-domain containing 4
chr2_+_91457501 1.090 ENSMUST00000028689.3
Lrp4
low density lipoprotein receptor-related protein 4
chr14_+_69347587 1.069 ENSMUST00000064831.5
Entpd4
ectonucleoside triphosphate diphosphohydrolase 4
chr5_-_138187177 1.054 ENSMUST00000110937.1
ENSMUST00000139276.1
ENSMUST00000048698.7
ENSMUST00000123415.1
Taf6



TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor



chr15_-_37459327 1.021 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr3_-_59220150 1.001 ENSMUST00000170388.1
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr12_-_79296266 0.998 ENSMUST00000021547.6
Zfyve26
zinc finger, FYVE domain containing 26
chr2_-_28916668 0.994 ENSMUST00000113847.1
Barhl1
BarH-like 1 (Drosophila)
chr4_-_14621669 0.933 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr18_+_57142782 0.930 ENSMUST00000139892.1
Megf10
multiple EGF-like-domains 10
chr10_-_8886033 0.908 ENSMUST00000015449.5
Sash1
SAM and SH3 domain containing 1
chr14_+_47298260 0.905 ENSMUST00000166743.1
Mapk1ip1l
mitogen-activated protein kinase 1 interacting protein 1-like
chr17_+_17402672 0.903 ENSMUST00000115576.2
Lix1
limb expression 1 homolog (chicken)
chr12_+_38780284 0.880 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr4_-_42661893 0.860 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr2_+_71389239 0.844 ENSMUST00000028408.2
Hat1
histone aminotransferase 1
chr15_+_39006272 0.796 ENSMUST00000179165.1
ENSMUST00000022906.7
Fzd6

frizzled homolog 6 (Drosophila)

chr5_-_137072254 0.739 ENSMUST00000077523.3
ENSMUST00000041388.4
Serpine1

serine (or cysteine) peptidase inhibitor, clade E, member 1

chr1_+_78310295 0.738 ENSMUST00000036172.8
Sgpp2
sphingosine-1-phosphate phosphotase 2
chr15_-_63997969 0.727 ENSMUST00000164532.1
Fam49b
family with sequence similarity 49, member B
chr16_-_89818338 0.710 ENSMUST00000164263.2
Tiam1
T cell lymphoma invasion and metastasis 1
chrX_-_101086020 0.699 ENSMUST00000113710.1
Slc7a3
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
chr12_+_38781093 0.669 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr5_-_62765618 0.633 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_+_114851142 0.632 ENSMUST00000133245.1
ENSMUST00000122967.2
Gprc5c

G protein-coupled receptor, family C, group 5, member C

chr4_-_117682233 0.622 ENSMUST00000102687.3
Dmap1
DNA methyltransferase 1-associated protein 1
chr5_+_48242549 0.610 ENSMUST00000172493.1
Slit2
slit homolog 2 (Drosophila)
chr1_-_163725123 0.577 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr14_-_52104015 0.571 ENSMUST00000111610.4
ENSMUST00000164655.1
Hnrnpc

heterogeneous nuclear ribonucleoprotein C

chr14_+_118854695 0.567 ENSMUST00000100314.3
Cldn10
claudin 10
chr5_+_138116903 0.557 ENSMUST00000062350.8
ENSMUST00000110961.2
ENSMUST00000080732.3
ENSMUST00000110960.2
ENSMUST00000142185.1
ENSMUST00000136425.1
ENSMUST00000110959.1
Zscan21






zinc finger and SCAN domain containing 21






chr1_+_161070767 0.546 ENSMUST00000111618.1
ENSMUST00000111620.3
ENSMUST00000028035.7
Cenpl


centromere protein L


chr14_+_25980039 0.546 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr2_+_19371636 0.542 ENSMUST00000023856.8
Msrb2
methionine sulfoxide reductase B2
chr4_-_129227883 0.532 ENSMUST00000106051.1
C77080
expressed sequence C77080
chr7_+_101896340 0.526 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
Anapc15


anaphase prompoting complex C subunit 15


chr3_+_66219909 0.524 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr11_-_109611417 0.522 ENSMUST00000103060.3
ENSMUST00000047186.3
ENSMUST00000106689.1
Wipi1


WD repeat domain, phosphoinositide interacting 1


chr12_+_38780817 0.512 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr1_-_161070613 0.506 ENSMUST00000035430.3
Dars2
aspartyl-tRNA synthetase 2 (mitochondrial)
chr6_+_125552948 0.502 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr2_-_29787622 0.499 ENSMUST00000177467.1
ENSMUST00000113807.3
Trub2

TruB pseudouridine (psi) synthase homolog 2 (E. coli)

chrX_+_169685191 0.498 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr3_-_33082004 0.494 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr8_-_112011320 0.480 ENSMUST00000034426.6
Kars
lysyl-tRNA synthetase
chrX_-_160138375 0.477 ENSMUST00000033662.8
Pdha1
pyruvate dehydrogenase E1 alpha 1
chr2_+_91257323 0.475 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr3_+_125404292 0.474 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr3_+_125404072 0.466 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr8_-_112011266 0.446 ENSMUST00000164470.1
ENSMUST00000093120.5
Kars

lysyl-tRNA synthetase

chr14_+_26119811 0.445 ENSMUST00000173617.1
Duxbl2
doubl homeobox B-like 2
chr3_+_19187321 0.445 ENSMUST00000130806.1
ENSMUST00000117529.1
ENSMUST00000119865.1
Mtfr1


mitochondrial fission regulator 1


chrM_+_8600 0.441 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr5_-_149051300 0.421 ENSMUST00000110505.1
Hmgb1
high mobility group box 1
chr11_+_60537978 0.394 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr4_+_62525369 0.394 ENSMUST00000062145.1
4933430I17Rik
RIKEN cDNA 4933430I17 gene
chr6_-_122340499 0.379 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr11_+_58171648 0.378 ENSMUST00000020820.1
Mrpl22
mitochondrial ribosomal protein L22
chr12_-_80643799 0.375 ENSMUST00000166931.1
Erh
enhancer of rudimentary homolog (Drosophila)
chr5_-_3647806 0.372 ENSMUST00000119783.1
ENSMUST00000007559.8
Gatad1

GATA zinc finger domain containing 1

chr8_-_34965631 0.367 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr14_+_79515618 0.358 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr3_+_5218516 0.353 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr14_+_26259109 0.337 ENSMUST00000174494.1
Duxbl3
double homeobox B-like 3
chr2_-_164389095 0.332 ENSMUST00000167427.1
Slpi
secretory leukocyte peptidase inhibitor
chr9_-_39603635 0.327 ENSMUST00000119722.1
AW551984
expressed sequence AW551984
chr2_-_160619971 0.326 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr5_-_100416115 0.301 ENSMUST00000182886.1
ENSMUST00000094578.4
Sec31a

Sec31 homolog A (S. cerevisiae)

chr6_+_63255971 0.299 ENSMUST00000159561.1
ENSMUST00000095852.3
Grid2

glutamate receptor, ionotropic, delta 2

chr3_+_88297147 0.299 ENSMUST00000164166.1
ENSMUST00000168062.1
Cct3

chaperonin containing Tcp1, subunit 3 (gamma)

chr7_+_100159241 0.297 ENSMUST00000032967.3
Lipt2
lipoyl(octanoyl) transferase 2 (putative)
chr4_+_95557494 0.296 ENSMUST00000079223.4
ENSMUST00000177394.1
Fggy

FGGY carbohydrate kinase domain containing

chr7_+_38183217 0.295 ENSMUST00000165308.1
1600014C10Rik
RIKEN cDNA 1600014C10 gene
chr7_+_19368498 0.295 ENSMUST00000132655.1
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr6_-_54566484 0.290 ENSMUST00000019268.4
Scrn1
secernin 1
chr3_+_88297115 0.276 ENSMUST00000001452.7
Cct3
chaperonin containing Tcp1, subunit 3 (gamma)
chr8_-_106573461 0.275 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr14_-_104522615 0.271 ENSMUST00000022716.2
Rnf219
ring finger protein 219
chr3_+_53488677 0.263 ENSMUST00000029307.3
Stoml3
stomatin (Epb7.2)-like 3
chr2_+_69897255 0.238 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr12_+_80644212 0.237 ENSMUST00000085245.5
Slc39a9
solute carrier family 39 (zinc transporter), member 9
chr17_-_47502276 0.236 ENSMUST00000067103.2
Taf8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factorq
chr3_+_55782500 0.235 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr1_-_152625212 0.213 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr2_+_76650264 0.213 ENSMUST00000099986.2
Dfnb59
deafness, autosomal recessive 59 (human)
chr10_-_33995054 0.195 ENSMUST00000164429.1
Gm17567
predicted gene, 17567
chr4_+_154964117 0.193 ENSMUST00000030931.4
ENSMUST00000070953.4
Pank4

pantothenate kinase 4

chr5_-_88675190 0.188 ENSMUST00000133532.1
ENSMUST00000150438.1
Grsf1

G-rich RNA sequence binding factor 1

chr16_-_92400067 0.187 ENSMUST00000023672.8
Rcan1
regulator of calcineurin 1
chr6_-_30693676 0.184 ENSMUST00000169422.1
ENSMUST00000115131.1
ENSMUST00000115130.2
ENSMUST00000031810.8
Cep41



centrosomal protein 41



chr1_+_93421682 0.178 ENSMUST00000096427.4
Gm17415
predicted gene, 17415
chr4_+_103143052 0.176 ENSMUST00000106855.1
Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr16_-_87495704 0.172 ENSMUST00000176750.1
ENSMUST00000175977.1
Cct8

chaperonin containing Tcp1, subunit 8 (theta)

chr4_+_100478806 0.169 ENSMUST00000133493.2
ENSMUST00000092730.3
ENSMUST00000106979.3
Ube2u


ubiquitin-conjugating enzyme E2U (putative)


chr13_-_97747373 0.164 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr3_+_103739366 0.163 ENSMUST00000106852.1
Gm10964
predicted gene 10964
chr9_-_50659780 0.148 ENSMUST00000034567.3
Dlat
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
chr15_+_98571004 0.138 ENSMUST00000023728.6
4930415O20Rik
RIKEN cDNA 4930415O20 gene
chr11_-_99230998 0.130 ENSMUST00000103133.3
Smarce1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr19_-_32196393 0.129 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1
chr8_+_36489191 0.119 ENSMUST00000171777.1
6430573F11Rik
RIKEN cDNA 6430573F11 gene
chr2_-_91649751 0.114 ENSMUST00000099714.3
Zfp408
zinc finger protein 408
chr9_+_94669876 0.104 ENSMUST00000033463.9
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chrX_+_106920618 0.096 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr1_+_110099295 0.095 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr6_+_47920476 0.089 ENSMUST00000009411.8
Zfp212
Zinc finger protein 212
chr1_-_172027269 0.088 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr9_-_103222063 0.088 ENSMUST00000170904.1
Trf
transferrin
chr2_+_110597298 0.088 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr9_+_37208291 0.078 ENSMUST00000034632.8
Tmem218
transmembrane protein 218
chr13_-_97747399 0.076 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr9_+_27299205 0.076 ENSMUST00000115247.1
ENSMUST00000133213.1
Igsf9b

immunoglobulin superfamily, member 9B

chr18_-_24603464 0.071 ENSMUST00000154205.1
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr8_-_41016749 0.065 ENSMUST00000117735.1
Mtus1
mitochondrial tumor suppressor 1
chr7_+_101896817 0.048 ENSMUST00000143835.1
Anapc15
anaphase prompoting complex C subunit 15
chr10_+_116018213 0.048 ENSMUST00000063470.4
Ptprr
protein tyrosine phosphatase, receptor type, R
chrM_+_7759 0.045 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr14_-_100149764 0.044 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr6_+_145934113 0.044 ENSMUST00000032383.7
Sspn
sarcospan
chr16_-_32877723 0.028 ENSMUST00000119810.1
1700021K19Rik
RIKEN cDNA 1700021K19 gene
chrX_+_107255878 0.026 ENSMUST00000101294.2
ENSMUST00000118820.1
ENSMUST00000120971.1
Gpr174


G protein-coupled receptor 174


chr4_+_108719649 0.022 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr10_-_117148474 0.020 ENSMUST00000020381.3
Frs2
fibroblast growth factor receptor substrate 2
chr6_-_136875794 0.020 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr1_+_134405984 0.019 ENSMUST00000173908.1
Cyb5r1
cytochrome b5 reductase 1
chr10_+_127420867 0.008 ENSMUST00000064793.6
R3hdm2
R3H domain containing 2
chr5_-_63968867 0.007 ENSMUST00000154169.1
Rell1
RELT-like 1
chr9_-_13818665 0.006 ENSMUST00000150893.1
ENSMUST00000124883.1
Cep57

centrosomal protein 57

chr10_-_76110956 0.002 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.2 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
1.6 6.4 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.3 4.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.8 2.3 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.6 1.8 GO:0006059 hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401)
0.6 1.8 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.6 2.3 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.6 10.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.4 1.1 GO:1904395 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.4 2.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 1.1 GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.3 0.9 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.3 1.2 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.3 0.9 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.3 0.9 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.3 2.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.2 0.7 GO:0010757 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) negative regulation of plasminogen activation(GO:0010757) regulation of vascular wound healing(GO:0061043) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 0.7 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.2 0.6 GO:0050929 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.2 1.8 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.2 0.5 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.2 0.8 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.2 2.1 GO:0031017 exocrine pancreas development(GO:0031017)
0.1 0.6 GO:0090365 regulation of mRNA modification(GO:0090365)
0.1 0.4 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.1 0.7 GO:0015819 lysine transport(GO:0015819)
0.1 1.8 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 2.3 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.4 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.1 0.6 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 1.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.3 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 4.7 GO:0051693 actin filament capping(GO:0051693)
0.1 0.4 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.5 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.7 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.1 1.6 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.3 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.1 3.6 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.7 GO:0006670 sphingosine metabolic process(GO:0006670)
0.1 0.5 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.1 2.3 GO:0030901 midbrain development(GO:0030901)
0.0 1.2 GO:0006907 pinocytosis(GO:0006907)
0.0 0.9 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 0.6 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 3.3 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.5 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.3 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 1.9 GO:0007601 visual perception(GO:0007601)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.6 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.9 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0 0.2 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.4 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.0 0.3 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 1.0 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 1.0 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 1.3 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.5 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0097454 Schwann cell microvillus(GO:0097454)
0.3 1.3 GO:0008623 CHRAC(GO:0008623)
0.3 2.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 1.2 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.7 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.5 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.9 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.6 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.7 GO:0060091 kinocilium(GO:0060091)
0.1 1.1 GO:0016600 flotillin complex(GO:0016600)
0.1 10.7 GO:0000792 heterochromatin(GO:0000792)
0.1 0.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 2.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 3.6 GO:0016459 myosin complex(GO:0016459)
0.1 1.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0034709 methylosome(GO:0034709)
0.0 0.6 GO:0045120 pronucleus(GO:0045120)
0.0 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 2.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 6.4 GO:0030426 growth cone(GO:0030426)
0.0 1.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 1.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.6 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 4.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.1 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0005118 sevenless binding(GO:0005118)
0.5 6.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.3 1.8 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 1.8 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 1.8 GO:0031432 titin binding(GO:0031432)
0.2 2.1 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.2 1.1 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.2 1.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 2.3 GO:0016594 glycine binding(GO:0016594)
0.1 1.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.4 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.1 0.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 2.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.5 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.6 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 1.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 2.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.7 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.4 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.6 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.5 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.1 1.6 GO:0070410 co-SMAD binding(GO:0070410)
0.1 1.8 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 3.6 GO:0030507 spectrin binding(GO:0030507)
0.1 0.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.5 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.8 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 1.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.5 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 11.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 5.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.7 GO:0017161 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.0 0.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.9 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 1.4 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812)
0.0 1.3 GO:0004601 peroxidase activity(GO:0004601)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 2.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 10.1 GO:0044212 transcription regulatory region DNA binding(GO:0044212)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0042556 cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.1 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.3 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.1 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)