Motif ID: Gzf1

Z-value: 0.474


Transcription factors associated with Gzf1:

Gene SymbolEntrez IDGene Name
Gzf1 ENSMUSG00000027439.9 Gzf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gzf1mm10_v2_chr2_+_148681023_148681197-0.402.2e-02Click!


Activity profile for motif Gzf1.

activity profile for motif Gzf1


Sorted Z-values histogram for motif Gzf1

Sorted Z-values for motif Gzf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gzf1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_47594629 3.320 ENSMUST00000182846.1
Ccnd3
cyclin D3
chr14_+_19751257 3.274 ENSMUST00000022340.3
Nid2
nidogen 2
chr11_-_33163072 2.318 ENSMUST00000093201.6
ENSMUST00000101375.4
ENSMUST00000109354.3
ENSMUST00000075641.3
Npm1



nucleophosmin 1



chr13_+_37826225 2.203 ENSMUST00000128570.1
Rreb1
ras responsive element binding protein 1
chr16_+_65815508 1.651 ENSMUST00000168064.1
Vgll3
vestigial like 3 (Drosophila)
chr4_-_129542710 1.467 ENSMUST00000102597.4
Hdac1
histone deacetylase 1
chr14_+_55854115 1.465 ENSMUST00000168479.1
Nynrin
NYN domain and retroviral integrase containing
chr8_-_78508876 1.435 ENSMUST00000049245.7
Rbmxl1
RNA binding motif protein, X linked-like-1
chr14_+_11227511 1.349 ENSMUST00000080237.3
Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr17_-_55915870 1.305 ENSMUST00000074828.4
Rpl21-ps6
ribosomal protein L21, pseudogene 6
chr4_+_154960915 1.190 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr6_-_52012476 1.179 ENSMUST00000078214.5
Skap2
src family associated phosphoprotein 2
chr14_+_55853997 1.103 ENSMUST00000100529.3
Nynrin
NYN domain and retroviral integrase containing
chr4_-_134128707 0.826 ENSMUST00000105879.1
ENSMUST00000030651.8
Sh3bgrl3

SH3 domain binding glutamic acid-rich protein-like 3

chr17_+_71204647 0.722 ENSMUST00000126681.1
Lpin2
lipin 2
chr12_+_109540979 0.648 ENSMUST00000129245.1
ENSMUST00000143836.1
ENSMUST00000124106.1
Meg3


maternally expressed 3


chr7_-_29168647 0.638 ENSMUST00000048923.6
Spred3
sprouty-related, EVH1 domain containing 3
chr1_+_15805639 0.597 ENSMUST00000027057.6
Terf1
telomeric repeat binding factor 1
chr7_-_30612731 0.572 ENSMUST00000006476.4
Upk1a
uroplakin 1A
chr8_+_78509319 0.554 ENSMUST00000034111.8
Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr8_+_105855086 0.515 ENSMUST00000040445.7
Thap11
THAP domain containing 11
chr2_+_162931520 0.497 ENSMUST00000130411.1
Srsf6
serine/arginine-rich splicing factor 6
chr4_+_129513581 0.494 ENSMUST00000062356.6
Marcksl1
MARCKS-like 1
chr9_-_116175318 0.081 ENSMUST00000061101.4
ENSMUST00000035014.6
Tgfbr2

transforming growth factor, beta receptor II


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:1904749 rRNA export from nucleus(GO:0006407) regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.3 2.6 GO:0015074 DNA integration(GO:0015074)
0.3 1.2 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.3 2.2 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601) regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.2 1.5 GO:0061198 fungiform papilla formation(GO:0061198) positive regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000343) positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.2 0.6 GO:0031627 telomeric loop formation(GO:0031627)
0.2 3.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.5 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 1.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.6 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.7 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.8 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.0 3.3 GO:0007160 cell-matrix adhesion(GO:0007160)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 GO:0001652 granular component(GO:0001652)
0.2 1.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.6 GO:0070187 telosome(GO:0070187)
0.1 1.5 GO:0016580 Sin3 complex(GO:0016580)
0.1 3.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 3.3 GO:0005604 basement membrane(GO:0005604)
0.0 0.5 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.2 0.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 2.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 3.3 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.6 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 1.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.8 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 2.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.4 GO:0001047 core promoter binding(GO:0001047)