Z-value: 6.749
Transcription factors associated with Hdx:
Activity-expression correlation:
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Showing 1 to 20 of 105 entries
Gene overrepresentation in biological_process category:
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Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihood Term Description
0.1
1434.9
GO:0008150 biological_process(GO:0008150)
9.7
58.3
GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4
20.8
GO:0021884 forebrain neuron development(GO:0021884)
0.6
18.7
GO:0006270 DNA replication initiation(GO:0006270)
4.3
13.0
GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
3.8
11.5
GO:1990046 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
1.7
8.3
GO:0019659 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.3
6.5
GO:0097352 autophagosome maturation(GO:0097352)
0.8
5.8
GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.1
5.4
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
1.3
5.2
GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.3
5.2
GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.2
4.8
GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.9
4.7
GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) prolactin signaling pathway(GO:0038161)
0.6
4.1
GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.2
4.0
GO:0034063 stress granule assembly(GO:0034063)
0.9
2.8
GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.8
2.5
GO:0002295 T-helper cell lineage commitment(GO:0002295)
0.1
2.2
GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1
2.1
GO:0019430 removal of superoxide radicals(GO:0019430)
Gene overrepresentation in cellular_component category:
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Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihood Term Description
0.1
1535.7
GO:0005575 cellular_component(GO:0005575)
3.5
20.8
GO:0001674 female germ cell nucleus(GO:0001674)
0.7
11.5
GO:0042101 T cell receptor complex(GO:0042101)
0.2
11.2
GO:0005876 spindle microtubule(GO:0005876)
0.6
8.3
GO:0035686 sperm fibrous sheath(GO:0035686)
0.3
5.8
GO:0071564 npBAF complex(GO:0071564)
0.1
4.3
GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.4
4.1
GO:0001739 sex chromatin(GO:0001739)
0.9
3.4
GO:0032021 NELF complex(GO:0032021)
0.3
3.1
GO:0031080 nuclear pore outer ring(GO:0031080)
0.8
2.5
GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.4
2.2
GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2
2.1
GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1
1.9
GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1
1.6
GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2
1.5
GO:0005638 lamin filament(GO:0005638)
0.3
1.1
GO:1990130 Iml1 complex(GO:1990130)
0.1
1.1
GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2
0.8
GO:0060187 cell pole(GO:0060187)
Gene overrepresentation in molecular_function category:
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Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihood Term Description
0.1
1482.6
GO:0003674 molecular_function(GO:0003674)
0.2
40.2
GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
4.3
13.0
GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
3.8
11.5
GO:1901611 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.6
11.2
GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
2.1
8.3
GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.4
6.3
GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1
5.8
GO:0031491 nucleosome binding(GO:0031491)
1.7
5.2
GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.3
5.2
GO:0070403 NAD+ binding(GO:0070403)
0.2
4.8
GO:0004708 MAP kinase kinase activity(GO:0004708)
0.6
4.7
GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.1
4.7
GO:0017046 peptide hormone binding(GO:0017046)
0.4
4.0
GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2
4.0
GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2
3.1
GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2
2.8
GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.3
2.5
GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.3
2.2
GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3
2.1
GO:0008097 5S rRNA binding(GO:0008097)
