Motif ID: Hic1

Z-value: 1.915


Transcription factors associated with Hic1:

Gene SymbolEntrez IDGene Name
Hic1 ENSMUSG00000043099.4 Hic1



Activity profile for motif Hic1.

activity profile for motif Hic1


Sorted Z-values histogram for motif Hic1

Sorted Z-values for motif Hic1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hic1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84800024 14.314 ENSMUST00000126806.1
ENSMUST00000076715.6
 Nfix

nuclear factor I/X

chr8_-_84800344 9.096 ENSMUST00000099070.3
 Nfix
nuclear factor I/X
chr5_-_62766153 7.690 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_-_32222233 7.529 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
 Rhbdf1


rhomboid family 1 (Drosophila)


chr3_-_88000350 7.299 ENSMUST00000090971.5
 Bcan
brevican
chr9_+_45430293 7.296 ENSMUST00000034592.8
 Dscaml1
Down syndrome cell adhesion molecule like 1
chr4_-_139092958 6.356 ENSMUST00000042844.6
 Nbl1
neuroblastoma, suppression of tumorigenicity 1
chr18_-_80986578 5.955 ENSMUST00000057950.7
 Sall3
sal-like 3 (Drosophila)
chr1_-_79858627 5.932 ENSMUST00000027467.4
 Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr7_+_130936172 5.614 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr7_+_117380937 5.547 ENSMUST00000032892.5
 Xylt1
xylosyltransferase 1
chr6_+_90550789 5.519 ENSMUST00000130418.1
ENSMUST00000032175.8
 Aldh1l1

aldehyde dehydrogenase 1 family, member L1

chr2_+_71117923 5.418 ENSMUST00000028403.2
 Cybrd1
cytochrome b reductase 1
chr11_+_63131512 5.245 ENSMUST00000018361.3
 Pmp22
peripheral myelin protein 22
chr10_-_9675163 5.062 ENSMUST00000100070.2
 Samd5
sterile alpha motif domain containing 5
chr4_-_46991842 5.039 ENSMUST00000107749.2
 Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr17_+_26715644 5.011 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
 Crebrf



CREB3 regulatory factor



chr17_-_31636631 4.895 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
 Cbs


cystathionine beta-synthase


chr9_+_26733845 4.894 ENSMUST00000115269.2
 B3gat1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr7_+_113207465 4.891 ENSMUST00000047321.7
 Arntl
aryl hydrocarbon receptor nuclear translocator-like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 450 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 30.0 GO:0021683 cerebellar granular layer morphogenesis(GO:0021683)
0.9 18.9 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
3.2 9.6 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.1 9.1 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.1 7.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
2.3 7.0 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
0.3 7.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 6.8 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.8 6.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
2.1 6.4 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.5 6.4 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.9 6.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.4 6.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.4 5.9 GO:0032060 bleb assembly(GO:0032060)
0.4 5.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.9 5.6 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
1.8 5.5 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
1.8 5.5 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.4 5.5 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.6 5.1 GO:0048681 negative regulation of axon regeneration(GO:0048681)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 157 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 122.7 GO:0016021 integral component of membrane(GO:0016021)
0.0 31.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 23.2 GO:0000139 Golgi membrane(GO:0000139)
0.5 13.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 13.0 GO:0005901 caveola(GO:0005901)
0.1 11.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 11.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 9.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.3 8.2 GO:0051233 spindle midzone(GO:0051233)
0.2 6.5 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 6.2 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.5 6.0 GO:0031091 platelet alpha granule(GO:0031091)
0.7 5.8 GO:0033391 chromatoid body(GO:0033391)
0.1 5.6 GO:0031901 early endosome membrane(GO:0031901)
0.1 5.6 GO:0031526 brush border membrane(GO:0031526)
0.3 5.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
1.0 5.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
1.6 4.8 GO:0072534 perineuronal net(GO:0072534)
0.3 4.8 GO:0043196 varicosity(GO:0043196)
0.5 4.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 294 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 15.3 GO:0005096 GTPase activator activity(GO:0005096)
2.3 13.8 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.6 12.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.3 12.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
3.2 9.6 GO:0098809 nitrite reductase activity(GO:0098809)
0.2 9.6 GO:0019894 kinesin binding(GO:0019894)
1.9 9.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 8.7 GO:0030332 cyclin binding(GO:0030332)
0.1 8.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.4 7.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 7.1 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 7.0 GO:0008017 microtubule binding(GO:0008017)
0.3 6.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
2.1 6.4 GO:0016015 morphogen activity(GO:0016015)
0.5 6.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 6.3 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.3 6.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
1.2 5.9 GO:2001070 starch binding(GO:2001070)
0.8 5.9 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.7 5.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)