Motif ID: Hlf

Z-value: 0.906


Transcription factors associated with Hlf:

Gene SymbolEntrez IDGene Name
Hlf ENSMUSG00000003949.10 Hlf

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hlfmm10_v2_chr11_-_90390895_903909260.699.1e-06Click!


Activity profile for motif Hlf.

activity profile for motif Hlf


Sorted Z-values histogram for motif Hlf

Sorted Z-values for motif Hlf



Network of associatons between targets according to the STRING database.



First level regulatory network of Hlf

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_65971049 6.522 ENSMUST00000128539.1
Clu
clusterin
chr14_+_65970804 6.110 ENSMUST00000138191.1
Clu
clusterin
chr14_+_65971164 5.845 ENSMUST00000144619.1
Clu
clusterin
chr15_-_88978958 5.795 ENSMUST00000042594.6
ENSMUST00000109368.1
Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

chr4_-_151044564 3.615 ENSMUST00000103204.4
Per3
period circadian clock 3
chr10_+_94576254 3.435 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr17_-_31637135 3.375 ENSMUST00000118504.1
ENSMUST00000078509.5
ENSMUST00000067801.6
Cbs


cystathionine beta-synthase


chr11_-_101785252 3.356 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr9_-_107668967 3.280 ENSMUST00000177567.1
Slc38a3
solute carrier family 38, member 3
chr18_-_80713062 3.274 ENSMUST00000170905.1
ENSMUST00000078049.4
Nfatc1

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

chr6_+_90465287 2.754 ENSMUST00000113530.1
Klf15
Kruppel-like factor 15
chr9_+_94669876 2.530 ENSMUST00000033463.9
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr19_-_50678642 2.368 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr3_+_127553462 2.359 ENSMUST00000043108.4
4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr7_+_110773658 2.185 ENSMUST00000143786.1
Ampd3
adenosine monophosphate deaminase 3
chr13_+_49504774 2.144 ENSMUST00000051504.7
Ecm2
extracellular matrix protein 2, female organ and adipocyte specific
chr10_-_70592782 1.907 ENSMUST00000162251.1
Phyhipl
phytanoyl-CoA hydroxylase interacting protein-like
chr11_+_110997487 1.865 ENSMUST00000106635.1
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr15_+_25758755 1.829 ENSMUST00000131834.1
ENSMUST00000124966.1
Myo10

myosin X

chr18_+_50030977 1.806 ENSMUST00000145726.1
ENSMUST00000128377.1
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr17_-_43543639 1.798 ENSMUST00000178772.1
Ankrd66
ankyrin repeat domain 66
chr6_+_83034173 1.795 ENSMUST00000000707.2
ENSMUST00000101257.3
Loxl3

lysyl oxidase-like 3

chr3_+_86070915 1.724 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chr11_-_87826023 1.722 ENSMUST00000103177.3
Lpo
lactoperoxidase
chr11_+_110968016 1.707 ENSMUST00000106636.1
ENSMUST00000180023.1
Kcnj16

potassium inwardly-rectifying channel, subfamily J, member 16

chr7_+_110774240 1.705 ENSMUST00000147587.1
Ampd3
adenosine monophosphate deaminase 3
chrX_+_166238901 1.702 ENSMUST00000112235.1
Gpm6b
glycoprotein m6b
chr3_-_80913528 1.672 ENSMUST00000107743.1
ENSMUST00000029654.8
Glrb

glycine receptor, beta subunit

chr2_+_25180737 1.667 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr15_-_50889691 1.659 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr15_+_99393574 1.659 ENSMUST00000162624.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr15_+_99393610 1.659 ENSMUST00000159531.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr5_-_124032214 1.647 ENSMUST00000040967.7
Vps37b
vacuolar protein sorting 37B (yeast)
chr7_-_114636299 1.643 ENSMUST00000032906.4
ENSMUST00000032907.7
Calca

calcitonin/calcitonin-related polypeptide, alpha

chrX_-_155216444 1.598 ENSMUST00000026318.8
Sat1
spermidine/spermine N1-acetyl transferase 1
chrX_-_155216338 1.581 ENSMUST00000112551.3
Sat1
spermidine/spermine N1-acetyl transferase 1
chr8_-_92355764 1.568 ENSMUST00000180102.1
ENSMUST00000179421.1
ENSMUST00000179222.1
ENSMUST00000179029.1
4933436C20Rik



RIKEN cDNA 4933436C20 gene



chr7_+_27447978 1.552 ENSMUST00000037399.9
ENSMUST00000108358.1
Blvrb

biliverdin reductase B (flavin reductase (NADPH))

chr1_-_91459254 1.487 ENSMUST00000069620.8
Per2
period circadian clock 2
chr18_-_35498856 1.459 ENSMUST00000025215.8
Sil1
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr11_+_110968056 1.430 ENSMUST00000125692.1
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr10_-_31445921 1.428 ENSMUST00000000305.5
Tpd52l1
tumor protein D52-like 1
chr1_+_10993452 1.418 ENSMUST00000027056.5
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr9_+_38719024 1.377 ENSMUST00000129598.1
Vwa5a
von Willebrand factor A domain containing 5A
chr5_+_3343893 1.366 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr3_-_88762244 1.359 ENSMUST00000183267.1
Syt11
synaptotagmin XI
chr1_+_156838915 1.351 ENSMUST00000111720.1
Angptl1
angiopoietin-like 1
chr3_+_40800054 1.322 ENSMUST00000168287.1
Plk4
polo-like kinase 4
chr3_+_66219909 1.315 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr12_+_37241633 1.291 ENSMUST00000049874.7
Agmo
alkylglycerol monooxygenase
chr10_+_20347788 1.289 ENSMUST00000169712.1
Mtfr2
mitochondrial fission regulator 2
chr11_-_77894096 1.258 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr2_+_30834972 1.254 ENSMUST00000113592.2
Prrx2
paired related homeobox 2
chr2_+_116900152 1.251 ENSMUST00000126467.1
ENSMUST00000128305.1
ENSMUST00000155323.1
D330050G23Rik


RIKEN cDNA D330050G23 gene


chr2_-_109280718 1.193 ENSMUST00000147770.1
Mettl15
methyltransferase like 15
chr7_+_18884679 1.189 ENSMUST00000032573.6
Pglyrp1
peptidoglycan recognition protein 1
chr17_+_47737030 1.185 ENSMUST00000086932.3
Tfeb
transcription factor EB
chr4_+_111720187 1.136 ENSMUST00000084354.3
Spata6
spermatogenesis associated 6
chr3_+_51559973 1.108 ENSMUST00000180404.1
5031434O11Rik
RIKEN cDNA 5031434O11 gene
chr9_-_71163224 1.091 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr4_-_89311021 1.089 ENSMUST00000097981.4
Cdkn2b
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr11_-_88718223 1.075 ENSMUST00000107909.1
Msi2
musashi RNA-binding protein 2
chr11_-_106216318 1.067 ENSMUST00000002043.3
Ccdc47
coiled-coil domain containing 47
chr6_+_124808885 1.062 ENSMUST00000143040.1
ENSMUST00000052727.4
ENSMUST00000130160.1
Spsb2


splA/ryanodine receptor domain and SOCS box containing 2


chr19_+_34290653 1.056 ENSMUST00000025691.5
ENSMUST00000112472.2
Fas

Fas (TNF receptor superfamily member 6)

chr12_+_105563123 1.040 ENSMUST00000001652.5
Bdkrb2
bradykinin receptor, beta 2
chr11_+_3330401 1.030 ENSMUST00000045153.4
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr4_-_97584605 1.029 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr17_-_14694223 0.989 ENSMUST00000170872.1
Thbs2
thrombospondin 2
chrX_-_36864238 0.987 ENSMUST00000115249.3
ENSMUST00000115248.3
C330007P06Rik

RIKEN cDNA C330007P06 gene

chr16_+_43510267 0.978 ENSMUST00000114695.2
Zbtb20
zinc finger and BTB domain containing 20
chr11_+_3330781 0.968 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr4_-_97584612 0.954 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr15_+_34238026 0.938 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr1_-_140183404 0.929 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr17_+_70561739 0.879 ENSMUST00000097288.2
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr6_-_83033422 0.870 ENSMUST00000089651.5
Dok1
docking protein 1
chr17_+_79614900 0.822 ENSMUST00000040368.2
Rmdn2
regulator of microtubule dynamics 2
chr3_+_40800013 0.816 ENSMUST00000026858.5
ENSMUST00000170825.1
Plk4

polo-like kinase 4

chr2_+_120609383 0.802 ENSMUST00000124187.1
Haus2
HAUS augmin-like complex, subunit 2
chr10_-_17947997 0.800 ENSMUST00000037879.6
Heca
headcase homolog (Drosophila)
chr8_-_92356103 0.786 ENSMUST00000034183.3
4933436C20Rik
RIKEN cDNA 4933436C20 gene
chr13_+_93771656 0.779 ENSMUST00000091403.4
Arsb
arylsulfatase B
chr15_-_98728120 0.766 ENSMUST00000003445.6
Fkbp11
FK506 binding protein 11
chr3_+_96104498 0.749 ENSMUST00000132980.1
ENSMUST00000138206.1
ENSMUST00000090785.2
ENSMUST00000035519.5
Otud7b



OTU domain containing 7B



chr5_-_5514730 0.718 ENSMUST00000115445.1
ENSMUST00000179804.1
ENSMUST00000125110.1
ENSMUST00000115446.1
Cldn12



claudin 12



chr3_+_97158767 0.706 ENSMUST00000090759.4
Acp6
acid phosphatase 6, lysophosphatidic
chr5_-_147894804 0.703 ENSMUST00000118527.1
ENSMUST00000031655.3
ENSMUST00000138244.1
Slc46a3


solute carrier family 46, member 3


chr11_+_69045640 0.686 ENSMUST00000108666.1
ENSMUST00000021277.5
Aurkb

aurora kinase B

chr14_+_50955992 0.662 ENSMUST00000095925.4
Pnp2
purine-nucleoside phosphorylase 2
chr2_+_131909928 0.661 ENSMUST00000091288.6
Prnp
prion protein
chr17_-_24073479 0.653 ENSMUST00000017090.5
Kctd5
potassium channel tetramerisation domain containing 5
chr5_-_5514873 0.646 ENSMUST00000060947.7
Cldn12
claudin 12
chr7_+_90442729 0.644 ENSMUST00000061767.4
ENSMUST00000107206.1
Crebzf

CREB/ATF bZIP transcription factor

chr2_+_109280738 0.641 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr12_+_117843489 0.621 ENSMUST00000021592.9
Cdca7l
cell division cycle associated 7 like
chr16_+_91391721 0.614 ENSMUST00000160764.1
Gm21970
predicted gene 21970
chr5_+_8046077 0.605 ENSMUST00000088786.4
Sri
sorcin
chr16_-_16829276 0.587 ENSMUST00000023468.5
Spag6
sperm associated antigen 6
chr7_+_44496588 0.577 ENSMUST00000107927.3
Fam71e1
family with sequence similarity 71, member E1
chr14_+_78849171 0.567 ENSMUST00000040990.5
Vwa8
von Willebrand factor A domain containing 8
chr19_-_28963863 0.556 ENSMUST00000161813.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr7_+_67647405 0.550 ENSMUST00000032774.8
ENSMUST00000107471.1
Ttc23

tetratricopeptide repeat domain 23

chr16_-_4790220 0.540 ENSMUST00000118703.1
Cdip1
cell death inducing Trp53 target 1
chr14_+_50944499 0.539 ENSMUST00000178092.1
Pnp
purine-nucleoside phosphorylase
chr15_-_76307231 0.530 ENSMUST00000023222.6
ENSMUST00000164189.1
Oplah

5-oxoprolinase (ATP-hydrolysing)

chr13_+_114818232 0.522 ENSMUST00000166104.2
ENSMUST00000166176.2
ENSMUST00000184335.1
ENSMUST00000184245.1
ENSMUST00000015680.4
ENSMUST00000184214.1
ENSMUST00000165022.2
ENSMUST00000164737.1
ENSMUST00000184781.1
ENSMUST00000183407.1
ENSMUST00000184672.1
Mocs2










molybdenum cofactor synthesis 2










chr5_-_3473178 0.517 ENSMUST00000168422.1
Gm17590
predicted gene, 17590
chr16_-_4789887 0.514 ENSMUST00000117713.1
Cdip1
cell death inducing Trp53 target 1
chr11_-_101551837 0.512 ENSMUST00000017290.4
Brca1
breast cancer 1
chr3_-_30793549 0.508 ENSMUST00000180833.1
4933429H19Rik
RIKEN cDNA 4933429H19 gene
chrX_-_56598069 0.503 ENSMUST00000059899.2
Mmgt1
membrane magnesium transporter 1
chr7_+_30413744 0.493 ENSMUST00000032800.9
Tyrobp
TYRO protein tyrosine kinase binding protein
chr15_+_92597104 0.489 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr16_-_4789984 0.489 ENSMUST00000004173.5
Cdip1
cell death inducing Trp53 target 1
chr10_+_78574492 0.484 ENSMUST00000105384.3
Ilvbl
ilvB (bacterial acetolactate synthase)-like
chr8_+_123477859 0.457 ENSMUST00000001520.7
Afg3l1
AFG3(ATPase family gene 3)-like 1 (yeast)
chr4_-_98817537 0.447 ENSMUST00000102790.3
Kank4
KN motif and ankyrin repeat domains 4
chr16_-_59555752 0.446 ENSMUST00000179383.1
ENSMUST00000044604.8
Crybg3

beta-gamma crystallin domain containing 3

chr1_-_140183283 0.444 ENSMUST00000111977.1
Cfh
complement component factor h
chr2_+_118861954 0.435 ENSMUST00000028807.5
Ivd
isovaleryl coenzyme A dehydrogenase
chr16_+_92292380 0.434 ENSMUST00000047383.3
Kcne2
potassium voltage-gated channel, Isk-related subfamily, gene 2
chr7_-_44496406 0.426 ENSMUST00000118515.1
ENSMUST00000138328.1
ENSMUST00000008284.8
ENSMUST00000118808.1
Emc10



ER membrane protein complex subunit 10



chr16_-_94370450 0.425 ENSMUST00000138514.1
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr8_-_84840627 0.420 ENSMUST00000003911.6
ENSMUST00000109761.2
ENSMUST00000128035.1
Rad23a


RAD23a homolog (S. cerevisiae)


chr3_+_84952146 0.415 ENSMUST00000029727.7
Fbxw7
F-box and WD-40 domain protein 7
chr11_-_116086929 0.407 ENSMUST00000074628.6
ENSMUST00000106444.3
Wbp2

WW domain binding protein 2

chr2_-_120609283 0.401 ENSMUST00000102496.1
Lrrc57
leucine rich repeat containing 57
chr16_-_94370695 0.378 ENSMUST00000113906.2
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr12_+_24651346 0.376 ENSMUST00000020982.5
Klf11
Kruppel-like factor 11
chr2_-_120609500 0.363 ENSMUST00000133612.1
ENSMUST00000102498.1
ENSMUST00000102499.1
Lrrc57


leucine rich repeat containing 57


chr15_+_99074968 0.362 ENSMUST00000039665.6
Troap
trophinin associated protein
chr12_+_116281180 0.353 ENSMUST00000100986.2
Esyt2
extended synaptotagmin-like protein 2
chr7_-_42578588 0.351 ENSMUST00000179470.1
Gm21028
predicted gene, 21028
chr15_-_76307101 0.329 ENSMUST00000171340.1
Oplah
5-oxoprolinase (ATP-hydrolysing)
chr11_-_69980468 0.326 ENSMUST00000143175.1
Elp5
elongator acetyltransferase complex subunit 5
chr2_-_120609319 0.322 ENSMUST00000102497.3
Lrrc57
leucine rich repeat containing 57
chr10_+_81137953 0.322 ENSMUST00000117956.1
Zbtb7a
zinc finger and BTB domain containing 7a
chr1_+_180641330 0.316 ENSMUST00000085804.5
Lin9
lin-9 homolog (C. elegans)
chr9_-_114933811 0.303 ENSMUST00000084853.3
Gpd1l
glycerol-3-phosphate dehydrogenase 1-like
chr16_+_20097554 0.298 ENSMUST00000023509.3
Klhl24
kelch-like 24
chr2_+_132847719 0.294 ENSMUST00000124836.1
ENSMUST00000154160.1
Crls1

cardiolipin synthase 1

chr2_-_130642770 0.275 ENSMUST00000045761.6
Lzts3
leucine zipper, putative tumor suppressor family member 3
chr15_+_44619551 0.274 ENSMUST00000022964.7
Ebag9
estrogen receptor-binding fragment-associated gene 9
chr3_+_30792876 0.271 ENSMUST00000029256.7
Sec62
SEC62 homolog (S. cerevisiae)
chr2_-_20943413 0.269 ENSMUST00000140230.1
Arhgap21
Rho GTPase activating protein 21
chr16_-_57606816 0.263 ENSMUST00000114371.3
Cmss1
cms small ribosomal subunit 1
chr11_+_93996082 0.261 ENSMUST00000041956.7
Spag9
sperm associated antigen 9
chr12_-_110978981 0.257 ENSMUST00000135131.1
ENSMUST00000043459.6
ENSMUST00000128353.1
Ankrd9


ankyrin repeat domain 9


chr2_+_164879358 0.254 ENSMUST00000041643.3
Pcif1
PDX1 C-terminal inhibiting factor 1
chr10_-_61383523 0.252 ENSMUST00000020289.8
Pald1
phosphatase domain containing, paladin 1
chr2_+_131909951 0.248 ENSMUST00000124100.1
ENSMUST00000136783.1
PRND

prion protein gene complex (Prn), transcript variant 1, mRNA

chr10_-_121626316 0.247 ENSMUST00000039810.7
Xpot
exportin, tRNA (nuclear export receptor for tRNAs)
chr6_-_59024470 0.245 ENSMUST00000089860.5
Fam13a
family with sequence similarity 13, member A
chr16_-_94370647 0.241 ENSMUST00000113910.1
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr7_-_13034722 0.236 ENSMUST00000005711.4
Chmp2a
charged multivesicular body protein 2A
chr3_-_127553233 0.236 ENSMUST00000029588.5
Larp7
La ribonucleoprotein domain family, member 7
chr10_+_121739915 0.235 ENSMUST00000065600.7
ENSMUST00000136432.1
BC048403

cDNA sequence BC048403

chr16_-_87432597 0.224 ENSMUST00000039449.7
Ltn1
listerin E3 ubiquitin protein ligase 1
chr3_+_90062781 0.222 ENSMUST00000029551.2
1700094D03Rik
RIKEN cDNA 1700094D03 gene
chr13_-_100650981 0.214 ENSMUST00000022136.6
ENSMUST00000177848.1
Rad17

RAD17 homolog (S. pombe)

chr13_+_51100810 0.210 ENSMUST00000095797.5
Spin1
spindlin 1
chr3_+_96268654 0.209 ENSMUST00000098843.2
Hist2h3b
histone cluster 2, H3b
chr4_-_147868469 0.206 ENSMUST00000119975.2
Miip
migration and invasion inhibitory protein
chr2_+_69670100 0.195 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr16_+_36041184 0.189 ENSMUST00000042203.8
Wdr5b
WD repeat domain 5B
chr8_-_91133942 0.189 ENSMUST00000120213.1
ENSMUST00000109609.2
Aktip

thymoma viral proto-oncogene 1 interacting protein

chr2_+_181497165 0.189 ENSMUST00000149163.1
ENSMUST00000000844.8
ENSMUST00000184849.1
ENSMUST00000108800.1
ENSMUST00000069712.2
Tpd52l2




tumor protein D52-like 2




chr10_+_22645011 0.188 ENSMUST00000042261.4
Slc2a12
solute carrier family 2 (facilitated glucose transporter), member 12
chr10_+_88731056 0.183 ENSMUST00000116234.2
Arl1
ADP-ribosylation factor-like 1
chr4_-_147868631 0.176 ENSMUST00000030886.8
ENSMUST00000172710.1
Miip

migration and invasion inhibitory protein

chr12_+_73286779 0.164 ENSMUST00000140523.1
Slc38a6
solute carrier family 38, member 6
chr17_+_32284772 0.160 ENSMUST00000181112.1
Gm26549
predicted gene, 26549
chr1_-_69685937 0.150 ENSMUST00000027146.2
Ikzf2
IKAROS family zinc finger 2
chr19_-_7483212 0.149 ENSMUST00000088169.5
Rtn3
reticulon 3
chr11_-_6444352 0.147 ENSMUST00000093346.5
ENSMUST00000109737.2
H2afv

H2A histone family, member V

chr1_-_38129618 0.137 ENSMUST00000027251.6
Rev1
REV1 homolog (S. cerevisiae)
chr12_-_69159109 0.132 ENSMUST00000037023.8
Rps29
ribosomal protein S29
chr8_-_91134027 0.126 ENSMUST00000125257.1
Aktip
thymoma viral proto-oncogene 1 interacting protein
chr14_+_26122609 0.120 ENSMUST00000100810.6
Duxbl2
doubl homeobox B-like 2
chr8_+_105636509 0.107 ENSMUST00000005841.9
Ctcf
CCCTC-binding factor
chrX_-_12673540 0.106 ENSMUST00000060108.6
1810030O07Rik
RIKEN cDNA 1810030O07 gene
chr15_-_37007382 0.106 ENSMUST00000078976.7
Zfp706
zinc finger protein 706
chr19_+_43752996 0.106 ENSMUST00000026199.7
ENSMUST00000112047.3
ENSMUST00000153295.1
Cutc


cutC copper transporter homolog (E.coli)


chr2_+_104027823 0.103 ENSMUST00000111135.1
ENSMUST00000111136.1
ENSMUST00000102565.3
Fbxo3


F-box protein 3


chr3_+_87906321 0.102 ENSMUST00000005017.8
Hdgf
hepatoma-derived growth factor
chr5_-_150665560 0.080 ENSMUST00000118316.1
N4bp2l2
NEDD4 binding protein 2-like 2
chr1_+_109993982 0.071 ENSMUST00000027542.6
Cdh7
cadherin 7, type 2
chr14_+_70577839 0.069 ENSMUST00000089049.2
Nudt18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr9_-_100506844 0.065 ENSMUST00000112874.3
Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
chr1_-_58586191 0.062 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
Fam126b



family with sequence similarity 126, member B



chr18_-_80151467 0.061 ENSMUST00000066743.9
Adnp2
ADNP homeobox 2
chr10_-_62507737 0.060 ENSMUST00000020271.6
Srgn
serglycin
chr11_+_119022962 0.058 ENSMUST00000026662.7
Cbx2
chromobox 2
chr7_+_19228334 0.055 ENSMUST00000063976.8
Opa3
optic atrophy 3
chr3_+_51559757 0.052 ENSMUST00000180616.1
5031434O11Rik
RIKEN cDNA 5031434O11 gene
chr14_-_18893376 0.049 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr7_-_138846202 0.045 ENSMUST00000118810.1
ENSMUST00000075667.4
ENSMUST00000119664.1
Mapk1ip1


mitogen-activated protein kinase 1 interacting protein 1


chr12_+_73286868 0.045 ENSMUST00000153941.1
ENSMUST00000122920.1
ENSMUST00000101313.3
Slc38a6


solute carrier family 38, member 6


chr18_+_35771488 0.041 ENSMUST00000170693.1
Ube2d2a
ubiquitin-conjugating enzyme E2D 2A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 18.5 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
1.4 6.8 GO:0047484 regulation of response to osmotic stress(GO:0047484)
1.1 3.4 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
1.1 3.3 GO:0060854 patterning of lymph vessels(GO:0060854)
1.1 3.2 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.8 3.3 GO:0006867 asparagine transport(GO:0006867) glutamine transport(GO:0006868)
0.7 3.3 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.6 1.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.6 3.4 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.5 1.6 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.5 1.6 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.5 3.9 GO:0032264 IMP salvage(GO:0032264)
0.5 1.4 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.5 1.4 GO:1905154 negative regulation of tumor necrosis factor secretion(GO:1904468) negative regulation of membrane invagination(GO:1905154)
0.4 1.3 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.4 2.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.4 1.3 GO:0006553 lysine metabolic process(GO:0006553)
0.4 2.5 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.3 0.7 GO:0071280 cellular response to copper ion(GO:0071280)
0.3 1.6 GO:0042167 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.3 2.0 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 0.5 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.2 1.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2 3.6 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.2 0.2 GO:1903722 regulation of centriole elongation(GO:1903722)
0.2 2.8 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.2 0.7 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.2 1.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.1 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.2 1.7 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.2 1.2 GO:0098543 detection of bacterium(GO:0016045) negative regulation of natural killer cell activation(GO:0032815) detection of other organism(GO:0098543)
0.2 5.3 GO:0010107 potassium ion import(GO:0010107)
0.2 0.5 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 0.7 GO:0043101 purine-containing compound salvage(GO:0043101)
0.2 1.1 GO:0015791 polyol transport(GO:0015791) urea transport(GO:0015840) bile acid secretion(GO:0032782) urea transmembrane transport(GO:0071918)
0.2 0.8 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.2 0.5 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.2 1.7 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 1.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 1.2 GO:0070475 rRNA base methylation(GO:0070475)
0.1 1.1 GO:0006983 ER overload response(GO:0006983)
0.1 0.5 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 0.4 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.4 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.3 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.5 GO:2001204 regulation of osteoclast development(GO:2001204)
0.1 1.1 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.6 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 0.2 GO:0051031 tRNA transport(GO:0051031)
0.1 0.9 GO:0070842 aggresome assembly(GO:0070842)
0.1 1.7 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 0.4 GO:0006551 leucine metabolic process(GO:0006551)
0.1 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 1.1 GO:0031670 cellular response to nutrient(GO:0031670)
0.0 0.5 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.7 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.0 0.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 1.3 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 1.5 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.3 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.6 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 1.6 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 1.3 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 1.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.8 GO:0007584 response to nutrient(GO:0007584)
0.0 0.1 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 1.0 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 1.5 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.4 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 1.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 1.8 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 1.8 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 1.0 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 1.4 GO:0008344 adult locomotory behavior(GO:0008344)
0.0 0.8 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.3 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.2 GO:0007143 female meiotic division(GO:0007143)
0.0 0.8 GO:0051225 spindle assembly(GO:0051225)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 18.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.3 2.1 GO:0098536 deuterosome(GO:0098536)
0.2 1.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 0.6 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 1.7 GO:0000813 ESCRT I complex(GO:0000813)
0.2 1.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 2.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.5 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.8 GO:0070652 HAUS complex(GO:0070652)
0.1 0.6 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 1.0 GO:0031091 platelet alpha granule(GO:0031091)
0.1 0.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.5 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 7.0 GO:0055037 recycling endosome(GO:0055037)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 1.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.8 GO:0016459 myosin complex(GO:0016459)
0.0 1.4 GO:0005769 early endosome(GO:0005769)
0.0 1.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 5.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.8 GO:0005844 polysome(GO:0005844)
0.0 1.6 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 1.1 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 6.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 4.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0098809 nitrite reductase activity(GO:0098809)
1.1 3.2 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.8 18.5 GO:0051787 misfolded protein binding(GO:0051787)
0.7 2.0 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.7 3.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.7 3.3 GO:0015186 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.6 1.8 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.6 1.7 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.6 3.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 1.6 GO:0070052 collagen V binding(GO:0070052)
0.5 1.4 GO:0001851 complement component C3b binding(GO:0001851)
0.4 1.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.4 1.6 GO:0004074 biliverdin reductase activity(GO:0004074)
0.4 3.3 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.3 2.5 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.3 1.3 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.3 1.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.3 5.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.3 1.3 GO:0001849 complement component C1q binding(GO:0001849)
0.2 1.1 GO:0032027 myosin light chain binding(GO:0032027)
0.2 0.9 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2 1.1 GO:0015265 urea channel activity(GO:0015265)
0.2 1.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 1.0 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 1.0 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.7 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 1.7 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.7 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.5 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.1 1.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.3 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.3 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.1 1.1 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.5 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 6.0 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.6 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 1.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.6 GO:0051010 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.7 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 1.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.4 GO:0030332 cyclin binding(GO:0030332)
0.0 1.4 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.6 GO:0005179 hormone activity(GO:0005179)
0.0 1.4 GO:0030507 spectrin binding(GO:0030507)
0.0 1.1 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.4 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890)
0.0 0.1 GO:0052630 CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.0 0.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 1.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 4.3 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)