Motif ID: Hmga2

Z-value: 0.976


Transcription factors associated with Hmga2:

Gene SymbolEntrez IDGene Name
Hmga2 ENSMUSG00000056758.8 Hmga2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmga2mm10_v2_chr10_-_120476469_1204765270.038.7e-01Click!


Activity profile for motif Hmga2.

activity profile for motif Hmga2


Sorted Z-values histogram for motif Hmga2

Sorted Z-values for motif Hmga2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmga2

PNG image of the network

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Top targets:


Showing 1 to 20 of 133 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_3013140 8.287 ENSMUST00000143083.2
 Gm10721
predicted gene 10721
chr14_-_19418930 8.228 ENSMUST00000177817.1
 Gm21738
predicted gene, 21738
chr2_-_98667264 8.043 ENSMUST00000099683.1
 Gm10800
predicted gene 10800
chr9_+_3004457 7.069 ENSMUST00000178348.1
 Gm11168
predicted gene 11168
chr9_+_3023547 5.672 ENSMUST00000099046.3
 Gm10718
predicted gene 10718
chr9_+_3025417 5.537 ENSMUST00000075573.6
 Gm10717
predicted gene 10717
chr9_+_3018753 5.156 ENSMUST00000179272.1
 Gm10719
predicted gene 10719
chr9_+_3017408 4.577 ENSMUST00000099049.3
 Gm10719
predicted gene 10719
chr7_-_5413145 1.664 ENSMUST00000108569.2
 Vmn1r58
vomeronasal 1 receptor 58
chr5_+_14514918 1.240 ENSMUST00000030691.10
ENSMUST00000182407.1
 Pclo

piccolo (presynaptic cytomatrix protein)

chr13_-_62607499 1.219 ENSMUST00000091563.4
 6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr4_+_44756553 1.182 ENSMUST00000107824.2
 Zcchc7
zinc finger, CCHC domain containing 7
chr3_+_53845086 1.093 ENSMUST00000108014.1
 Gm10985
predicted gene 10985
chr1_-_144004142 0.989 ENSMUST00000127206.1
 Rgs2
regulator of G-protein signaling 2
chr16_+_96361749 0.956 ENSMUST00000000163.6
ENSMUST00000081093.3
ENSMUST00000113795.1
 Igsf5


immunoglobulin superfamily, member 5


chr1_+_172698046 0.949 ENSMUST00000038495.3
 Crp
C-reactive protein, pentraxin-related
chr12_-_87233556 0.887 ENSMUST00000021423.7
 Noxred1
NADP+ dependent oxidoreductase domain containing 1
chr2_-_148732457 0.882 ENSMUST00000028926.6
 Napb
N-ethylmaleimide sensitive fusion protein attachment protein beta
chr13_-_62371936 0.865 ENSMUST00000107989.3
 Gm3604
predicted gene 3604
chr9_+_58488568 0.841 ENSMUST00000085658.4
 6030419C18Rik
RIKEN cDNA 6030419C18 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.3 1.1 GO:0042938 dipeptide transport(GO:0042938)
0.2 1.0 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.3 0.9 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.2 0.9 GO:0032929 negative regulation of macrophage derived foam cell differentiation(GO:0010745) negative regulation of superoxide anion generation(GO:0032929)
0.1 0.9 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 0.9 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.8 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.8 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.7 GO:0031100 organ regeneration(GO:0031100)
0.1 0.6 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.5 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.5 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) cGMP catabolic process(GO:0046069)
0.0 0.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.5 GO:0000266 mitochondrial fission(GO:0000266)
0.1 0.4 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) positive regulation of cortisol secretion(GO:0051464)
0.1 0.4 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.4 GO:0031937 positive regulation of chromatin silencing(GO:0031937)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.2 GO:0044316 cone cell pedicle(GO:0044316)
0.2 0.9 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.9 GO:0070469 respiratory chain(GO:0070469)
0.1 0.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.4 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.3 GO:0044299 C-fiber(GO:0044299)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.2 GO:0005522 profilin binding(GO:0005522)
0.2 1.1 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 1.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 0.9 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 0.9 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 0.9 GO:0001849 complement component C1q binding(GO:0001849)
0.2 0.8 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.3 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.1 0.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)