Motif ID: Hmga2
Z-value: 0.976
Transcription factors associated with Hmga2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hmga2 | ENSMUSG00000056758.8 | Hmga2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Hmga2 | mm10_v2_chr10_-_120476469_120476527 | 0.03 | 8.7e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 0.9 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
0.3 | 1.1 | GO:0042938 | dipeptide transport(GO:0042938) |
0.2 | 1.2 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
0.2 | 1.0 | GO:0010519 | negative regulation of phospholipase activity(GO:0010519) |
0.2 | 0.9 | GO:0032929 | negative regulation of macrophage derived foam cell differentiation(GO:0010745) negative regulation of superoxide anion generation(GO:0032929) |
0.1 | 0.4 | GO:0042320 | regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) positive regulation of cortisol secretion(GO:0051464) |
0.1 | 0.5 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
0.1 | 0.4 | GO:0035521 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) histone H2A K63-linked deubiquitination(GO:0070537) |
0.1 | 0.9 | GO:0006561 | proline biosynthetic process(GO:0006561) |
0.1 | 0.3 | GO:1903232 | melanosome assembly(GO:1903232) |
0.1 | 0.8 | GO:0090315 | negative regulation of protein targeting to membrane(GO:0090315) |
0.1 | 0.9 | GO:0010807 | regulation of synaptic vesicle priming(GO:0010807) |
0.1 | 0.3 | GO:0046294 | formaldehyde catabolic process(GO:0046294) |
0.1 | 0.6 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
0.1 | 0.3 | GO:2000427 | regulation of apoptotic cell clearance(GO:2000425) positive regulation of apoptotic cell clearance(GO:2000427) |
0.1 | 0.2 | GO:0090071 | negative regulation of ribosome biogenesis(GO:0090071) |
0.0 | 0.2 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
0.0 | 0.2 | GO:0021631 | optic nerve morphogenesis(GO:0021631) |
0.0 | 0.1 | GO:0070269 | pyroptosis(GO:0070269) |
0.0 | 0.7 | GO:0031100 | organ regeneration(GO:0031100) |
0.0 | 0.4 | GO:0031937 | positive regulation of chromatin silencing(GO:0031937) |
0.0 | 0.5 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.0 | 0.3 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
0.0 | 0.4 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.0 | 0.1 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
0.0 | 0.8 | GO:0006182 | cGMP biosynthetic process(GO:0006182) |
0.0 | 0.5 | GO:0034390 | smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) cGMP catabolic process(GO:0046069) |
0.0 | 0.1 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
0.0 | 0.3 | GO:0070932 | histone H3 deacetylation(GO:0070932) |
0.0 | 0.3 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
0.0 | 0.1 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
0.0 | 0.1 | GO:0017121 | phospholipid scrambling(GO:0017121) |
0.0 | 0.4 | GO:0097120 | receptor localization to synapse(GO:0097120) |
0.0 | 0.5 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
0.0 | 0.6 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.0 | 0.1 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
0.0 | 0.5 | GO:0000266 | mitochondrial fission(GO:0000266) |
0.0 | 0.2 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.0 | 0.4 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
0.0 | 0.4 | GO:0034605 | cellular response to heat(GO:0034605) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.2 | GO:0044316 | cone cell pedicle(GO:0044316) |
0.2 | 0.9 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
0.1 | 0.6 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.1 | 0.3 | GO:0044299 | C-fiber(GO:0044299) |
0.1 | 0.8 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.1 | 0.7 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.0 | 0.4 | GO:0070688 | MLL5-L complex(GO:0070688) |
0.0 | 0.2 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.0 | 0.1 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
0.0 | 0.1 | GO:0061702 | inflammasome complex(GO:0061702) |
0.0 | 0.1 | GO:0036156 | inner dynein arm(GO:0036156) |
0.0 | 0.7 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.0 | 0.1 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
0.0 | 0.3 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.0 | 0.4 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.0 | 0.9 | GO:0070469 | respiratory chain(GO:0070469) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.9 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
0.2 | 0.9 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
0.2 | 1.1 | GO:0042895 | antibiotic transporter activity(GO:0042895) |
0.2 | 0.8 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
0.2 | 0.9 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.1 | 0.4 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
0.1 | 0.3 | GO:0018738 | S-formylglutathione hydrolase activity(GO:0018738) |
0.1 | 1.2 | GO:0005522 | profilin binding(GO:0005522) |
0.1 | 0.8 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
0.1 | 0.7 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.1 | 0.5 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.1 | 0.3 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
0.0 | 0.1 | GO:0001160 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) |
0.0 | 0.2 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.0 | 0.1 | GO:0061711 | N(6)-L-threonylcarbamoyladenine synthase(GO:0061711) |
0.0 | 0.4 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.0 | 0.5 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 0.7 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 1.0 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.0 | 0.7 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.0 | 0.5 | GO:0019789 | SUMO transferase activity(GO:0019789) |
0.0 | 0.5 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.0 | 0.0 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
0.0 | 0.3 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |