Motif ID: Hmx3

Z-value: 0.252


Transcription factors associated with Hmx3:

Gene SymbolEntrez IDGene Name
Hmx3 ENSMUSG00000040148.5 Hmx3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmx3mm10_v2_chr7_+_131542867_1315428670.291.0e-01Click!


Activity profile for motif Hmx3.

activity profile for motif Hmx3


Sorted Z-values histogram for motif Hmx3

Sorted Z-values for motif Hmx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmx3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_154328634 1.270 ENSMUST00000167744.1
 Lhx8
LIM homeobox protein 8
chr5_-_53707532 1.184 ENSMUST00000031093.3
 Cckar
cholecystokinin A receptor
chr3_-_86548268 0.994 ENSMUST00000077524.3
 Mab21l2
mab-21-like 2 (C. elegans)
chr3_-_49757257 0.818 ENSMUST00000035931.7
 Pcdh18
protocadherin 18
chr5_+_15516489 0.769 ENSMUST00000178227.1
 Gm21847
predicted gene, 21847
chr2_+_3114220 0.752 ENSMUST00000072955.5
 Fam171a1
family with sequence similarity 171, member A1
chr4_-_129261394 0.690 ENSMUST00000145261.1
 C77080
expressed sequence C77080
chrX_+_150594420 0.654 ENSMUST00000112713.2
 Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr2_-_72986716 0.533 ENSMUST00000112062.1
 Gm11084
predicted gene 11084
chr18_+_61639542 0.455 ENSMUST00000183083.1
ENSMUST00000183087.1
 Gm20748

predicted gene, 20748

chr1_-_78968079 0.454 ENSMUST00000049117.5
 Gm5830
predicted pseudogene 5830
chr10_-_80421847 0.452 ENSMUST00000156244.1
 Tcf3
transcription factor 3
chr13_+_118714678 0.441 ENSMUST00000022246.8
 Fgf10
fibroblast growth factor 10
chr3_+_96629919 0.405 ENSMUST00000048915.6
 Rbm8a
RNA binding motif protein 8a
chr10_+_99263224 0.401 ENSMUST00000020118.4
 Dusp6
dual specificity phosphatase 6
chr5_-_87482258 0.399 ENSMUST00000079811.6
ENSMUST00000144144.1
 Ugt2a1

UDP glucuronosyltransferase 2 family, polypeptide A1

chr6_+_86371489 0.371 ENSMUST00000089558.5
 Snrpg
small nuclear ribonucleoprotein polypeptide G
chr15_-_13173607 0.370 ENSMUST00000036439.4
 Cdh6
cadherin 6
chrM_+_9452 0.344 ENSMUST00000082411.1
 mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr17_-_35697971 0.343 ENSMUST00000146472.1
 Ddr1
discoidin domain receptor family, member 1
chrX_-_60893430 0.326 ENSMUST00000135107.2
 Sox3
SRY-box containing gene 3
chr12_-_83921809 0.322 ENSMUST00000135962.1
ENSMUST00000155112.1
ENSMUST00000136848.1
ENSMUST00000126943.1
 Numb



numb gene homolog (Drosophila)



chr8_-_23237623 0.307 ENSMUST00000033950.5
 Gins4
GINS complex subunit 4 (Sld5 homolog)
chr7_+_43690418 0.305 ENSMUST00000056329.6
 Klk14
kallikrein related-peptidase 14
chr4_-_62470868 0.301 ENSMUST00000135811.1
ENSMUST00000120095.1
ENSMUST00000030087.7
ENSMUST00000107452.1
ENSMUST00000155522.1
 Wdr31




WD repeat domain 31




chr5_+_121777929 0.287 ENSMUST00000160821.1
 Atxn2
ataxin 2
chr7_-_30559828 0.286 ENSMUST00000108164.1
 Lin37
lin-37 homolog (C. elegans)
chr12_-_83921899 0.256 ENSMUST00000117217.1
 Numb
numb gene homolog (Drosophila)
chr4_-_45532470 0.249 ENSMUST00000147448.1
 Shb
src homology 2 domain-containing transforming protein B
chr11_+_114668524 0.247 ENSMUST00000106602.3
ENSMUST00000077915.3
ENSMUST00000106599.1
ENSMUST00000082092.4
 Rpl38



ribosomal protein L38



chr12_+_108179738 0.198 ENSMUST00000101055.4
 Ccnk
cyclin K
chr2_-_84715160 0.190 ENSMUST00000035840.5
 Zdhhc5
zinc finger, DHHC domain containing 5
chr1_-_175979114 0.175 ENSMUST00000104983.1
 B020018G12Rik
RIKEN cDNA B020018G12 gene
chr9_+_21955747 0.152 ENSMUST00000053583.5
 Swsap1
SWIM type zinc finger 7 associated protein 1
chr7_+_3645267 0.149 ENSMUST00000038913.9
 Cnot3
CCR4-NOT transcription complex, subunit 3
chr17_-_57247632 0.138 ENSMUST00000005975.6
 Gpr108
G protein-coupled receptor 108
chr12_-_108179210 0.132 ENSMUST00000125916.2
ENSMUST00000109879.1
 Setd3

SET domain containing 3

chr7_-_30559600 0.128 ENSMUST00000043975.4
ENSMUST00000156241.1
 Lin37

lin-37 homolog (C. elegans)

chr19_+_8802486 0.126 ENSMUST00000172175.1
 Zbtb3
zinc finger and BTB domain containing 3
chr13_+_23746734 0.125 ENSMUST00000099703.2
 Hist1h2bb
histone cluster 1, H2bb
chr9_-_123678782 0.109 ENSMUST00000170591.1
ENSMUST00000171647.1
 Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr1_-_158814469 0.098 ENSMUST00000161589.2
 Pappa2
pappalysin 2
chr14_+_73552665 0.094 ENSMUST00000160507.1
ENSMUST00000022706.6
 Sucla2

succinate-Coenzyme A ligase, ADP-forming, beta subunit

chr19_-_41933276 0.071 ENSMUST00000075280.4
ENSMUST00000112123.2
 Exosc1

exosome component 1

chr7_-_127208423 0.063 ENSMUST00000120705.1
 Tbc1d10b
TBC1 domain family, member 10b
chr4_+_65604984 0.060 ENSMUST00000050850.7
ENSMUST00000107366.1
 Trim32

tripartite motif-containing 32

chrM_+_3906 0.052 ENSMUST00000082396.1
 mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr2_-_153015331 0.051 ENSMUST00000028972.8
 Pdrg1
p53 and DNA damage regulated 1
chr12_-_108179237 0.047 ENSMUST00000071095.7
 Setd3
SET domain containing 3
chr13_-_92131494 0.037 ENSMUST00000099326.3
ENSMUST00000146492.1
 Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr3_+_66985947 0.023 ENSMUST00000161726.1
ENSMUST00000160504.1
 Rsrc1

arginine/serine-rich coiled-coil 1

chr4_+_134397380 0.015 ENSMUST00000105870.1
 Pafah2
platelet-activating factor acetylhydrolase 2
chr19_+_41933464 0.007 ENSMUST00000026154.7
 Zdhhc16
zinc finger, DHHC domain containing 16
chr9_-_123678873 0.001 ENSMUST00000040960.6
 Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.2 0.6 GO:0030862 neuroblast division in subventricular zone(GO:0021849) regulation of polarized epithelial cell differentiation(GO:0030860) positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.1 0.4 GO:0071336 lung growth(GO:0060437) positive regulation of fat cell proliferation(GO:0070346) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 0.4 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.5 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.4 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.3 GO:0007320 insemination(GO:0007320)
0.0 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 1.0 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.2 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 1.3 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.3 GO:0007530 sex determination(GO:0007530)
0.0 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:1903265 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172) positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 1.3 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.3 GO:0000811 GINS complex(GO:0000811)
0.1 0.2 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.1 0.4 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.7 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.5 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 1.2 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 0.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)