Motif ID: Hnf1a

Z-value: 0.630


Transcription factors associated with Hnf1a:

Gene SymbolEntrez IDGene Name
Hnf1a ENSMUSG00000029556.6 Hnf1a



Activity profile for motif Hnf1a.

activity profile for motif Hnf1a


Sorted Z-values histogram for motif Hnf1a

Sorted Z-values for motif Hnf1a



Network of associatons between targets according to the STRING database.



First level regulatory network of Hnf1a

PNG image of the network

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Top targets:


Showing 1 to 20 of 56 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_144751968 3.203 ENSMUST00000155175.1
 Ano1
anoctamin 1, calcium activated chloride channel
chr9_-_106158109 2.564 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
 Glyctk



glycerate kinase



chr19_-_14598031 2.415 ENSMUST00000167776.2
 Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr19_-_14597983 2.034 ENSMUST00000052011.7
 Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr13_-_53286052 1.998 ENSMUST00000021918.8
 Ror2
receptor tyrosine kinase-like orphan receptor 2
chr7_-_79842287 1.955 ENSMUST00000049004.6
 Anpep
alanyl (membrane) aminopeptidase
chr2_-_68472138 1.588 ENSMUST00000102715.3
 Stk39
serine/threonine kinase 39
chr9_+_99629496 1.503 ENSMUST00000131095.1
ENSMUST00000078367.5
ENSMUST00000112885.2
 Dzip1l


DAZ interacting protein 1-like


chr10_+_87859255 1.494 ENSMUST00000105300.2
 Igf1
insulin-like growth factor 1
chr9_+_53771499 1.494 ENSMUST00000048670.8
 Slc35f2
solute carrier family 35, member F2
chr10_+_87859062 1.432 ENSMUST00000095360.4
 Igf1
insulin-like growth factor 1
chr9_+_57827284 1.381 ENSMUST00000163186.1
 Gm17231
predicted gene 17231
chr19_-_47919269 1.380 ENSMUST00000095998.5
 Itprip
inositol 1,4,5-triphosphate receptor interacting protein
chr11_+_3983636 1.338 ENSMUST00000078757.1
 Gal3st1
galactose-3-O-sulfotransferase 1
chr5_+_8046077 1.314 ENSMUST00000088786.4
 Sri
sorcin
chr11_+_3983704 1.263 ENSMUST00000063004.7
 Gal3st1
galactose-3-O-sulfotransferase 1
chr6_+_38918969 1.050 ENSMUST00000003017.6
 Tbxas1
thromboxane A synthase 1, platelet
chr9_+_99629823 1.014 ENSMUST00000112886.2
 Dzip1l
DAZ interacting protein 1-like
chr16_+_20651652 0.988 ENSMUST00000007212.8
 Psmd2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr11_+_78178105 0.986 ENSMUST00000147819.1
 Tlcd1
TLC domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 3.2 GO:0015705 iodide transport(GO:0015705)
0.7 2.9 GO:1904192 prostate gland stromal morphogenesis(GO:0060741) cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.3 2.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.9 2.6 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.4 2.0 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.3 2.0 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 2.0 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.5 1.6 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 1.4 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.2 1.3 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.2 1.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 1.0 GO:0051592 response to calcium ion(GO:0051592)
0.1 0.9 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.2 0.8 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.1 0.8 GO:0032782 urea transport(GO:0015840) bile acid secretion(GO:0032782) urea transmembrane transport(GO:0071918)
0.0 0.8 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.8 GO:0006821 chloride transport(GO:0006821)
0.2 0.7 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.7 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.2 0.6 GO:0030210 heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 3.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 3.1 GO:0000139 Golgi membrane(GO:0000139)
0.7 2.9 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0 2.5 GO:0005814 centriole(GO:0005814)
0.7 2.0 GO:0031983 vesicle lumen(GO:0031983)
0.0 2.0 GO:0008021 synaptic vesicle(GO:0008021)
0.4 1.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 1.0 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.1 0.9 GO:0005922 connexon complex(GO:0005922)
0.0 0.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.8 3.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 2.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.4 2.7 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.7 2.6 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.5 2.0 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.1 2.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 2.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.6 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 1.4 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 1.1 GO:0004497 monooxygenase activity(GO:0004497)
0.1 0.9 GO:0005243 gap junction channel activity(GO:0005243)
0.3 0.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 0.8 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.8 GO:0015265 urea channel activity(GO:0015265)
0.0 0.8 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.6 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.5 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)