Motif ID: Hnf4a

Z-value: 0.565


Transcription factors associated with Hnf4a:

Gene SymbolEntrez IDGene Name
Hnf4a ENSMUSG00000017950.10 Hnf4a



Activity profile for motif Hnf4a.

activity profile for motif Hnf4a


Sorted Z-values histogram for motif Hnf4a

Sorted Z-values for motif Hnf4a



Network of associatons between targets according to the STRING database.



First level regulatory network of Hnf4a

PNG image of the network

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Top targets:


Showing 1 to 20 of 174 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_104282371 1.536 ENSMUST00000106988.1
ENSMUST00000106989.1
 Mapt

microtubule-associated protein tau

chr7_+_25268387 1.405 ENSMUST00000169392.1
 Cic
capicua homolog (Drosophila)
chr14_+_101840602 1.374 ENSMUST00000159314.1
 Lmo7
LIM domain only 7
chr2_-_131042682 1.345 ENSMUST00000028787.5
ENSMUST00000110239.1
ENSMUST00000110234.1
 Gfra4


glial cell line derived neurotrophic factor family receptor alpha 4


chr2_-_131043088 1.227 ENSMUST00000110240.3
ENSMUST00000066958.4
ENSMUST00000110235.1
 Gfra4


glial cell line derived neurotrophic factor family receptor alpha 4


chr14_+_101840501 1.081 ENSMUST00000159026.1
 Lmo7
LIM domain only 7
chr3_-_84305385 1.074 ENSMUST00000122849.1
ENSMUST00000132283.1
 Trim2

tripartite motif-containing 2

chr13_-_41273977 1.067 ENSMUST00000163881.1
 Gm17364
predicted gene, 17364
chr1_-_155417394 1.039 ENSMUST00000111775.1
ENSMUST00000111774.1
 Xpr1

xenotropic and polytropic retrovirus receptor 1

chr4_+_136286061 1.016 ENSMUST00000069195.4
ENSMUST00000130658.1
 Zfp46

zinc finger protein 46

chrX_-_162565514 0.954 ENSMUST00000154424.1
 Reps2
RALBP1 associated Eps domain containing protein 2
chr6_+_86195214 0.863 ENSMUST00000032066.9
 Tgfa
transforming growth factor alpha
chr19_+_44992127 0.859 ENSMUST00000179305.1
 Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chrX_-_105929206 0.857 ENSMUST00000134381.1
ENSMUST00000154866.1
 Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chr5_+_19907774 0.857 ENSMUST00000115267.2
 Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr15_-_102722120 0.856 ENSMUST00000171838.1
 Calcoco1
calcium binding and coiled coil domain 1
chr17_-_91088726 0.829 ENSMUST00000072671.7
ENSMUST00000174331.1
ENSMUST00000161402.3
ENSMUST00000054059.8
 Nrxn1



neurexin I



chr2_+_71117923 0.815 ENSMUST00000028403.2
 Cybrd1
cytochrome b reductase 1
chrX_-_105929333 0.805 ENSMUST00000134507.1
ENSMUST00000137453.1
ENSMUST00000150914.1
 Atrx


alpha thalassemia/mental retardation syndrome X-linked homolog (human)


chr7_+_112225856 0.794 ENSMUST00000050149.5
ENSMUST00000106647.1
ENSMUST00000106648.1
 Mical2


microtubule associated monooxygenase, calponin and LIM domain containing 2



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.6 GO:0030279 negative regulation of ossification(GO:0030279)
0.5 2.2 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.3 2.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2 1.8 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 1.7 GO:0048286 lung alveolus development(GO:0048286)
0.3 1.6 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 1.5 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 1.4 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.3 1.0 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.0 1.0 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1 0.9 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.1 0.9 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.9 GO:0050919 negative chemotaxis(GO:0050919)
0.3 0.8 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 0.8 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.8 GO:0010039 response to iron ion(GO:0010039)
0.0 0.8 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.7 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.2 0.6 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.5 2.2 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.0 1.8 GO:0031225 anchored component of membrane(GO:0031225)
0.2 1.5 GO:0045298 tubulin complex(GO:0045298)
0.3 1.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 1.0 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.3 GO:0016460 myosin II complex(GO:0016460)
0.0 0.1 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.9 2.6 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 2.5 GO:0042805 actinin binding(GO:0042805)
0.3 2.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 1.9 GO:0017022 myosin binding(GO:0017022)
0.2 1.6 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 1.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.3 1.0 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 0.8 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.8 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.1 0.8 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.8 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.1 0.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 0.6 GO:0042731 PH domain binding(GO:0042731)
0.1 0.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 0.5 GO:0004126 cytidine deaminase activity(GO:0004126)