Motif ID: Hoxa1

Z-value: 0.778


Transcription factors associated with Hoxa1:

Gene SymbolEntrez IDGene Name
Hoxa1 ENSMUSG00000029844.9 Hoxa1



Activity profile for motif Hoxa1.

activity profile for motif Hoxa1


Sorted Z-values histogram for motif Hoxa1

Sorted Z-values for motif Hoxa1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa1

PNG image of the network

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Top targets:


Showing 1 to 20 of 90 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_15239045 4.239 ENSMUST00000034413.6
 Vstm5
V-set and transmembrane domain containing 5
chr14_+_70077375 3.590 ENSMUST00000035908.1
 Egr3
early growth response 3
chr14_-_103844173 2.928 ENSMUST00000022718.3
 Ednrb
endothelin receptor type B
chr4_-_143299498 2.903 ENSMUST00000030317.7
 Pdpn
podoplanin
chr2_+_152962485 2.353 ENSMUST00000099197.2
ENSMUST00000103155.3
 Ttll9

tubulin tyrosine ligase-like family, member 9

chr8_-_11312731 2.173 ENSMUST00000033898.9
 Col4a1
collagen, type IV, alpha 1
chr10_+_79988584 2.152 ENSMUST00000004784.4
ENSMUST00000105374.1
 Cnn2

calponin 2

chr4_-_106799779 2.083 ENSMUST00000145061.1
ENSMUST00000102762.3
 Acot11

acyl-CoA thioesterase 11

chr8_-_117673682 2.081 ENSMUST00000173522.1
ENSMUST00000174450.1
 Sdr42e1

short chain dehydrogenase/reductase family 42E, member 1

chr2_+_163225363 1.953 ENSMUST00000099110.3
ENSMUST00000165937.1
 Tox2

TOX high mobility group box family member 2

chr13_-_12340723 1.825 ENSMUST00000168193.1
ENSMUST00000110616.1
ENSMUST00000064204.7
 Actn2


actinin alpha 2


chr10_+_94576254 1.771 ENSMUST00000117929.1
 Tmcc3
transmembrane and coiled coil domains 3
chr16_+_38902305 1.652 ENSMUST00000023478.7
 Igsf11
immunoglobulin superfamily, member 11
chr17_+_70522083 1.624 ENSMUST00000148486.1
ENSMUST00000133717.1
 Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr6_-_52012476 1.615 ENSMUST00000078214.5
 Skap2
src family associated phosphoprotein 2
chr11_-_20332654 1.416 ENSMUST00000004634.6
 Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr17_+_70522149 1.296 ENSMUST00000140728.1
 Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr4_-_143299463 1.240 ENSMUST00000119654.1
 Pdpn
podoplanin
chr2_-_152951688 1.195 ENSMUST00000109811.3
 Dusp15
dual specificity phosphatase-like 15
chr15_+_74516196 1.158 ENSMUST00000042035.9
 Bai1
brain-specific angiogenesis inhibitor 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 4.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.3 3.6 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
1.0 2.9 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.2 2.9 GO:0070842 aggresome assembly(GO:0070842)
0.0 2.4 GO:0006694 steroid biosynthetic process(GO:0006694)
0.3 2.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.2 2.2 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.6 1.8 GO:0051695 actin filament uncapping(GO:0051695)
0.2 1.4 GO:0015808 L-alanine transport(GO:0015808)
0.4 1.1 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.1 1.1 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 1.1 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.3 1.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 1.0 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.9 GO:0001553 luteinization(GO:0001553)
0.0 0.9 GO:0010842 retina layer formation(GO:0010842)
0.3 0.8 GO:1905154 negative regulation of tumor necrosis factor secretion(GO:1904468) negative regulation of membrane invagination(GO:1905154)
0.0 0.8 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.2 0.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.7 GO:0042711 maternal behavior(GO:0042711)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.0 GO:0030175 filopodium(GO:0030175)
0.0 2.7 GO:0031965 nuclear membrane(GO:0031965)
0.4 2.2 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 2.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)
0.3 1.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 1.0 GO:0005876 spindle microtubule(GO:0005876)
0.1 0.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.6 GO:0097542 ciliary tip(GO:0097542)
0.1 0.5 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 4.1 GO:0008517 folic acid transporter activity(GO:0008517) water channel activity(GO:0015250)
1.0 2.9 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 2.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 2.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 2.1 GO:0034946 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.1 2.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 2.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.5 1.9 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.2 1.8 GO:0031432 thyroid hormone receptor coactivator activity(GO:0030375) titin binding(GO:0031432)
0.1 1.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 1.4 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.0 1.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.1 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.1 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.1 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.8 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.6 GO:0051183 vitamin transporter activity(GO:0051183)