Motif ID: Hoxa10

Z-value: 0.787


Transcription factors associated with Hoxa10:

Gene SymbolEntrez IDGene Name
Hoxa10 ENSMUSG00000000938.11 Hoxa10



Activity profile for motif Hoxa10.

activity profile for motif Hoxa10


Sorted Z-values histogram for motif Hoxa10

Sorted Z-values for motif Hoxa10



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa10

PNG image of the network

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Top targets:


Showing 1 to 20 of 162 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_102010138 3.380 ENSMUST00000066187.4
 Nhlh2
nescient helix loop helix 2
chr8_+_106935720 2.348 ENSMUST00000047425.3
 Sntb2
syntrophin, basic 2
chr5_-_131616599 2.139 ENSMUST00000161804.1
 Auts2
autism susceptibility candidate 2
chr3_+_67892189 2.088 ENSMUST00000063263.3
 Iqcj
IQ motif containing J
chr17_+_29093763 1.959 ENSMUST00000023829.6
 Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr11_+_44617310 1.957 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
 Ebf1


early B cell factor 1


chr8_-_33747724 1.767 ENSMUST00000179364.1
 Smim18
small integral membrane protein 18
chr19_+_4711153 1.680 ENSMUST00000008991.6
 Sptbn2
spectrin beta, non-erythrocytic 2
chr13_-_99516537 1.644 ENSMUST00000064762.4
 Map1b
microtubule-associated protein 1B
chr10_+_97565436 1.562 ENSMUST00000038160.4
 Lum
lumican
chr6_-_3494587 1.361 ENSMUST00000049985.8
 Hepacam2
HEPACAM family member 2
chr11_-_42000284 1.304 ENSMUST00000109292.2
ENSMUST00000109290.1
 Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr11_-_69822144 1.302 ENSMUST00000045771.6
 Spem1
sperm maturation 1
chr6_+_54264839 1.229 ENSMUST00000146114.1
 Chn2
chimerin (chimaerin) 2
chr3_-_123672321 1.221 ENSMUST00000172537.1
ENSMUST00000029602.6
 Ndst3

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

chr4_+_100776664 1.143 ENSMUST00000030257.8
ENSMUST00000097955.2
 Cachd1

cache domain containing 1

chr2_-_37647199 1.136 ENSMUST00000028279.3
 Strbp
spermatid perinuclear RNA binding protein
chr8_+_58912257 1.077 ENSMUST00000160055.1
 BC030500
cDNA sequence BC030500
chr9_+_62342449 1.064 ENSMUST00000156461.1
 Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr4_+_43406435 1.049 ENSMUST00000098106.2
ENSMUST00000139198.1
 Rusc2

RUN and SH3 domain containing 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.4 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 2.9 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.7 2.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.3 2.0 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.2 2.0 GO:0071493 cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399)
0.1 1.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.4 1.6 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 1.6 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.0 1.4 GO:0051297 centrosome organization(GO:0051297)
0.1 1.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 1.3 GO:0030317 sperm motility(GO:0030317)
0.0 1.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.3 1.0 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 1.0 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.3 0.9 GO:0016095 polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310)
0.0 0.9 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.0 0.9 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.8 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 0.7 GO:2000562 negative regulation of interferon-gamma secretion(GO:1902714) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.0 GO:0070557 PCNA-p21 complex(GO:0070557)
0.3 1.7 GO:0008091 spectrin(GO:0008091)
0.1 1.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.6 GO:0043196 varicosity(GO:0043196)
0.0 1.4 GO:0030496 midbody(GO:0030496)
0.1 1.3 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.1 GO:0016363 nuclear matrix(GO:0016363)
0.3 1.0 GO:0044299 C-fiber(GO:0044299)
0.1 1.0 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.8 GO:0070469 respiratory chain(GO:0070469)
0.2 0.7 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1 0.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.6 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.5 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 3.3 GO:0005516 calmodulin binding(GO:0005516)
0.3 2.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 2.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 2.0 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 2.0 GO:0003682 chromatin binding(GO:0003682)
0.0 2.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.3 1.8 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 1.6 GO:0005518 collagen binding(GO:0005518)
0.0 1.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 1.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 1.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 1.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 1.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.1 GO:0005178 integrin binding(GO:0005178)
0.1 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.0 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.9 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.2 0.8 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.8 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)