Motif ID: Hoxa2

Z-value: 0.984


Transcription factors associated with Hoxa2:

Gene SymbolEntrez IDGene Name
Hoxa2 ENSMUSG00000014704.8 Hoxa2



Activity profile for motif Hoxa2.

activity profile for motif Hoxa2


Sorted Z-values histogram for motif Hoxa2

Sorted Z-values for motif Hoxa2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_139543889 6.049 ENSMUST00000174792.1
ENSMUST00000031523.8
 Uncx

UNC homeobox

chr12_+_109747903 5.215 ENSMUST00000183084.1
ENSMUST00000182300.1
 Mirg

miRNA containing gene

chr16_-_23890805 4.586 ENSMUST00000004480.3
 Sst
somatostatin
chr7_+_45163915 3.675 ENSMUST00000085374.5
 Slc17a7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr5_-_24527276 3.027 ENSMUST00000088311.4
 Gbx1
gastrulation brain homeobox 1
chr2_-_117342949 2.425 ENSMUST00000102534.4
 Rasgrp1
RAS guanyl releasing protein 1
chr7_+_144838590 2.342 ENSMUST00000105898.1
 Fgf3
fibroblast growth factor 3
chr2_-_117342831 2.324 ENSMUST00000178884.1
 Rasgrp1
RAS guanyl releasing protein 1
chr13_+_117220584 2.268 ENSMUST00000022242.7
 Emb
embigin
chr3_+_55782500 2.246 ENSMUST00000075422.4
 Mab21l1
mab-21-like 1 (C. elegans)
chr8_-_87959560 2.206 ENSMUST00000109655.2
 Zfp423
zinc finger protein 423
chr2_-_117342709 2.085 ENSMUST00000173541.1
ENSMUST00000172901.1
ENSMUST00000173252.1
 Rasgrp1


RAS guanyl releasing protein 1


chr9_-_106158109 2.062 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
 Glyctk



glycerate kinase



chr9_+_51621425 2.048 ENSMUST00000089534.4
 Gm7293
predicted gene 7293
chr14_-_34374617 2.000 ENSMUST00000023826.4
 Sncg
synuclein, gamma
chr5_+_115235836 1.932 ENSMUST00000081497.6
 Pop5
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr10_-_92162753 1.893 ENSMUST00000182197.1
 Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr14_+_11227511 1.884 ENSMUST00000080237.3
 Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr2_-_84775420 1.836 ENSMUST00000111641.1
 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr2_-_84775388 1.815 ENSMUST00000023994.3
 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 149 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 6.8 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
1.2 6.2 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.9 6.0 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
1.2 3.7 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
1.2 3.7 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.8 3.0 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 2.8 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.3 2.3 GO:0030916 otic vesicle formation(GO:0030916) semicircular canal morphogenesis(GO:0048752)
0.1 2.3 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 2.2 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 2.2 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 2.1 GO:0006220 pyrimidine nucleotide metabolic process(GO:0006220)
0.3 1.9 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.9 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 1.7 GO:0097067 negative regulation of erythrocyte differentiation(GO:0045647) cellular response to thyroid hormone stimulus(GO:0097067)
0.2 1.6 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 1.6 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.1 1.6 GO:0007614 short-term memory(GO:0007614)
0.4 1.5 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 1.5 GO:0048844 artery morphogenesis(GO:0048844)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 75 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.6 1.9 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 1.9 GO:0005643 nuclear pore(GO:0005643)
0.4 1.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3 1.6 GO:0008091 spectrin(GO:0008091)
0.2 1.5 GO:0031262 Ndc80 complex(GO:0031262)
0.0 1.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.4 1.3 GO:0005584 collagen type I trimer(GO:0005584)
0.0 1.3 GO:0005581 collagen trimer(GO:0005581)
0.0 1.3 GO:0005776 autophagosome(GO:0005776)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.2 GO:0000922 spindle pole(GO:0000922)
0.0 1.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.1 GO:0000776 kinetochore(GO:0000776)
0.3 1.0 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 1.0 GO:0070852 cell body fiber(GO:0070852)
0.1 1.0 GO:0031045 dense core granule(GO:0031045)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 117 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 7.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 6.2 GO:0051183 vitamin transporter activity(GO:0051183)
1.2 3.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 3.7 GO:0001848 complement binding(GO:0001848)
0.0 3.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 2.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 2.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 2.3 GO:0005179 hormone activity(GO:0005179)
0.1 2.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.6 1.9 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 1.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.5 GO:0008565 protein transporter activity(GO:0008565)
0.2 1.4 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 1.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.3 GO:0015643 toxic substance binding(GO:0015643)
0.1 1.3 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.1 1.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.4 1.2 GO:0031750 D3 dopamine receptor binding(GO:0031750)