Motif ID: Hoxa3

Z-value: 0.508


Transcription factors associated with Hoxa3:

Gene SymbolEntrez IDGene Name
Hoxa3 ENSMUSG00000079560.7 Hoxa3



Activity profile for motif Hoxa3.

activity profile for motif Hoxa3


Sorted Z-values histogram for motif Hoxa3

Sorted Z-values for motif Hoxa3



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_168767136 3.452 ENSMUST00000029061.5
ENSMUST00000103074.1
 Sall4

sal-like 4 (Drosophila)

chr3_+_55782500 3.021 ENSMUST00000075422.4
 Mab21l1
mab-21-like 1 (C. elegans)
chr17_-_70853482 2.955 ENSMUST00000118283.1
 Tgif1
TGFB-induced factor homeobox 1
chr2_-_168767029 2.618 ENSMUST00000075044.3
 Sall4
sal-like 4 (Drosophila)
chr9_+_119063429 2.534 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
 Vill


villin-like


chr2_+_109917639 1.456 ENSMUST00000046548.7
ENSMUST00000111037.2
 Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr13_-_102905740 1.291 ENSMUST00000167462.1
 Mast4
microtubule associated serine/threonine kinase family member 4
chr13_-_102906046 1.271 ENSMUST00000171791.1
 Mast4
microtubule associated serine/threonine kinase family member 4
chr3_+_159839729 1.211 ENSMUST00000068952.5
 Wls
wntless homolog (Drosophila)
chr3_-_86548268 1.039 ENSMUST00000077524.3
 Mab21l2
mab-21-like 2 (C. elegans)
chr17_+_17402672 0.810 ENSMUST00000115576.2
 Lix1
limb expression 1 homolog (chicken)
chr10_+_37139558 0.763 ENSMUST00000062667.3
 5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr10_-_37138863 0.763 ENSMUST00000092584.5
 Marcks
myristoylated alanine rich protein kinase C substrate
chr12_+_59013379 0.645 ENSMUST00000021379.7
 Gemin2
gem (nuclear organelle) associated protein 2
chr5_-_138187177 0.595 ENSMUST00000110937.1
ENSMUST00000139276.1
ENSMUST00000048698.7
ENSMUST00000123415.1
 Taf6



TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor



chr7_-_38019505 0.539 ENSMUST00000085513.4
 Uri1
URI1, prefoldin-like chaperone
chr5_+_138187485 0.523 ENSMUST00000110934.2
 Cnpy4
canopy 4 homolog (zebrafish)
chr1_-_172027269 0.489 ENSMUST00000027837.6
ENSMUST00000111264.1
 Vangl2

vang-like 2 (van gogh, Drosophila)

chr2_+_36230426 0.351 ENSMUST00000062069.5
 Ptgs1
prostaglandin-endoperoxide synthase 1
chr16_-_45724600 0.342 ENSMUST00000096057.4
 Tagln3
transgelin 3
chr2_-_164171113 0.207 ENSMUST00000045196.3
 Kcns1
K+ voltage-gated channel, subfamily S, 1
chr5_-_137531952 0.191 ENSMUST00000140139.1
 Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr2_-_69712461 0.152 ENSMUST00000102706.3
ENSMUST00000073152.6
 Fastkd1

FAST kinase domains 1

chr4_-_14621669 0.146 ENSMUST00000143105.1
 Slc26a7
solute carrier family 26, member 7
chr7_-_45103747 0.144 ENSMUST00000003512.7
 Fcgrt
Fc receptor, IgG, alpha chain transporter
chr11_+_95384662 0.142 ENSMUST00000021243.7
ENSMUST00000146556.1
 Slc35b1

solute carrier family 35, member B1

chr5_-_137531204 0.141 ENSMUST00000150063.2
 Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr16_-_92400067 0.112 ENSMUST00000023672.8
 Rcan1
regulator of calcineurin 1
chr14_+_79515618 0.104 ENSMUST00000110835.1
 Elf1
E74-like factor 1
chr14_+_64589802 0.100 ENSMUST00000180610.1
 A930011O12Rik
RIKEN cDNA A930011O12 gene
chr10_+_26772477 0.083 ENSMUST00000039557.7
 Arhgap18
Rho GTPase activating protein 18
chr7_-_116038734 0.063 ENSMUST00000166877.1
 Sox6
SRY-box containing gene 6
chr15_-_11037968 0.043 ENSMUST00000058007.5
 Rxfp3
relaxin family peptide receptor 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.3 6.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 3.0 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 0.5 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.4 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.1 1.2 GO:0031017 exocrine pancreas development(GO:0031017)
0.1 2.5 GO:0051693 actin filament capping(GO:0051693)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 1.0 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.5 GO:0060187 cell pole(GO:0060187)
0.0 0.6 GO:0032797 SMN complex(GO:0032797)
0.0 6.1 GO:0000792 heterochromatin(GO:0000792)
0.0 1.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.6 GO:0033276 transcription factor TFTC complex(GO:0033276)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 GO:0070410 co-SMAD binding(GO:0070410)
0.1 1.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 1.2 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 2.6 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.8 GO:0005080 protein kinase C binding(GO:0005080)