Motif ID: Hoxa4

Z-value: 0.866


Transcription factors associated with Hoxa4:

Gene SymbolEntrez IDGene Name
Hoxa4 ENSMUSG00000000942.10 Hoxa4



Activity profile for motif Hoxa4.

activity profile for motif Hoxa4


Sorted Z-values histogram for motif Hoxa4

Sorted Z-values for motif Hoxa4



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_80802789 8.550 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr2_+_90885860 7.214 ENSMUST00000111466.2
 C1qtnf4
C1q and tumor necrosis factor related protein 4
chr5_-_84417359 6.354 ENSMUST00000113401.1
 Epha5
Eph receptor A5
chr2_+_71528657 5.837 ENSMUST00000126400.1
 Dlx1
distal-less homeobox 1
chr2_+_170731807 5.374 ENSMUST00000029075.4
 Dok5
docking protein 5
chr5_+_17574726 4.856 ENSMUST00000169603.1
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr1_+_19103022 4.799 ENSMUST00000037294.7
 Tfap2d
transcription factor AP-2, delta
chr11_+_57011945 3.961 ENSMUST00000094179.4
 Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr11_+_57011798 3.921 ENSMUST00000036315.9
 Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr12_+_29528382 3.802 ENSMUST00000049784.9
 Myt1l
myelin transcription factor 1-like
chr4_+_119814495 3.688 ENSMUST00000106307.2
 Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr14_-_79771305 3.637 ENSMUST00000039568.5
 Pcdh8
protocadherin 8
chrX_+_159840463 3.318 ENSMUST00000112451.1
ENSMUST00000112453.2
 Sh3kbp1

SH3-domain kinase binding protein 1

chr2_-_6884975 3.101 ENSMUST00000114924.3
ENSMUST00000170438.1
ENSMUST00000114934.4
 Celf2


CUGBP, Elav-like family member 2


chr4_+_144892813 2.991 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr8_+_47713266 2.947 ENSMUST00000180928.1
 E030037K01Rik
RIKEN cDNA E030037K01 gene
chr18_+_37489465 2.910 ENSMUST00000055949.2
 Pcdhb18
protocadherin beta 18
chr4_+_101550411 2.891 ENSMUST00000094953.4
ENSMUST00000106933.1
 Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr1_+_178529113 2.802 ENSMUST00000161017.1
 Kif26b
kinesin family member 26B
chr2_+_124610573 2.780 ENSMUST00000103239.3
ENSMUST00000103240.2
 Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 82 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 16.5 GO:0001919 regulation of receptor recycling(GO:0001919)
0.1 11.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 9.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.8 9.0 GO:0042572 retinol metabolic process(GO:0042572)
0.8 7.8 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
1.9 5.8 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.1 5.5 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.5 5.4 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 5.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 5.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.7 4.9 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
1.4 4.3 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.7 4.3 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 4.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 4.0 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.9 2.8 GO:0072092 ureteric bud invasion(GO:0072092)
0.2 2.8 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 2.7 GO:0008542 visual learning(GO:0008542)
0.5 2.4 GO:0046684 response to pyrethroid(GO:0046684)
0.2 2.4 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 12.4 GO:0005911 cell-cell junction(GO:0005911)
0.5 8.5 GO:0032279 asymmetric synapse(GO:0032279)
1.3 7.9 GO:0044308 axonal spine(GO:0044308)
0.1 6.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 5.7 GO:0042641 actomyosin(GO:0042641)
0.0 5.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 4.9 GO:0030425 dendrite(GO:0030425)
0.0 2.8 GO:0005871 kinesin complex(GO:0005871)
0.0 2.8 GO:0060076 excitatory synapse(GO:0060076)
0.1 2.4 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 2.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.6 2.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 2.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 2.0 GO:0030027 lamellipodium(GO:0030027)
0.0 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.7 GO:0005581 collagen trimer(GO:0005581)
0.2 1.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 1.5 GO:0016605 PML body(GO:0016605)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.3 16.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
1.2 8.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.0 7.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 5.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 5.5 GO:0005057 receptor signaling protein activity(GO:0005057)
0.4 4.9 GO:0038191 neuropilin binding(GO:0038191)
0.2 4.3 GO:0030275 LRR domain binding(GO:0030275)
0.0 4.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 3.9 GO:0045296 cadherin binding(GO:0045296)
0.0 3.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 3.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 2.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 2.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 2.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 2.4 GO:0031402 sodium ion binding(GO:0031402)
0.3 2.3 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 2.3 GO:0002039 p53 binding(GO:0002039)
0.1 2.1 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 1.9 GO:0043531 ADP binding(GO:0043531)
0.3 1.7 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)