Motif ID: Hoxa5

Z-value: 0.817


Transcription factors associated with Hoxa5:

Gene SymbolEntrez IDGene Name
Hoxa5 ENSMUSG00000038253.6 Hoxa5



Activity profile for motif Hoxa5.

activity profile for motif Hoxa5


Sorted Z-values histogram for motif Hoxa5

Sorted Z-values for motif Hoxa5



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_57455898 3.598 ENSMUST00000034023.3
 Scrg1
scrapie responsive gene 1
chr11_+_16752203 3.064 ENSMUST00000102884.3
ENSMUST00000020329.6
 Egfr

epidermal growth factor receptor

chr17_-_31636631 2.964 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
 Cbs


cystathionine beta-synthase


chr9_+_37367354 2.750 ENSMUST00000051839.7
 Hepacam
hepatocyte cell adhesion molecule
chrX_+_66653003 2.392 ENSMUST00000036043.4
 Slitrk2
SLIT and NTRK-like family, member 2
chr9_+_94669876 2.321 ENSMUST00000033463.9
 Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr2_+_14388316 2.275 ENSMUST00000114731.1
ENSMUST00000082290.7
 Slc39a12

solute carrier family 39 (zinc transporter), member 12

chr3_+_62419668 2.254 ENSMUST00000161057.1
 Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr7_+_87803815 2.022 ENSMUST00000125009.1
ENSMUST00000155358.1
 Grm5

glutamate receptor, metabotropic 5

chr7_+_88278085 1.952 ENSMUST00000032779.5
ENSMUST00000128791.1
 Ctsc

cathepsin C

chr5_-_62766153 1.927 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr9_-_58313189 1.762 ENSMUST00000061799.8
 Loxl1
lysyl oxidase-like 1
chr1_+_169655493 1.739 ENSMUST00000027997.3
 Rgs5
regulator of G-protein signaling 5
chr1_+_104768510 1.680 ENSMUST00000062528.8
 Cdh20
cadherin 20
chr16_+_43508118 1.611 ENSMUST00000114690.1
 Zbtb20
zinc finger and BTB domain containing 20
chr15_-_37459327 1.594 ENSMUST00000119730.1
ENSMUST00000120746.1
 Ncald

neurocalcin delta

chr5_-_62765618 1.564 ENSMUST00000159470.1
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_+_102589687 1.523 ENSMUST00000097949.4
ENSMUST00000106901.1
 Pde4b

phosphodiesterase 4B, cAMP specific

chr4_+_136143497 1.424 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chr2_+_10153563 1.389 ENSMUST00000026886.7
 Itih5
inter-alpha (globulin) inhibitor H5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 182 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 3.2 GO:0097369 sodium ion import(GO:0097369)
0.8 3.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 3.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.0 3.0 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.3 3.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 3.0 GO:0007050 cell cycle arrest(GO:0007050)
0.4 2.5 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 2.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 2.3 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 2.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 2.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 2.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 2.0 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 1.5 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.5 1.4 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 1.4 GO:0071398 cellular response to fatty acid(GO:0071398)
0.1 1.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.4 1.3 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 1.3 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 1.3 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.7 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
1.0 3.1 GO:0031983 vesicle lumen(GO:0031983)
0.1 2.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 2.5 GO:0055037 recycling endosome(GO:0055037)
0.2 2.0 GO:0097449 astrocyte projection(GO:0097449)
0.0 1.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.5 GO:0005770 late endosome(GO:0005770)
0.0 1.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.4 1.3 GO:0005927 muscle tendon junction(GO:0005927)
0.0 1.1 GO:0042641 actomyosin(GO:0042641)
0.3 1.0 GO:0001533 cornified envelope(GO:0001533)
0.1 1.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.0 GO:0097542 ciliary tip(GO:0097542)
0.1 1.0 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 1.0 GO:0030315 T-tubule(GO:0030315)
0.0 0.9 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.2 0.8 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.8 GO:0005662 DNA replication factor A complex(GO:0005662)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 118 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
1.0 3.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 3.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
1.0 3.0 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 3.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 2.5 GO:0038191 neuropilin binding(GO:0038191)
0.3 2.3 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.7 2.0 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.1 2.0 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.1 1.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.6 1.8 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.0 1.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 1.6 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 1.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.4 GO:0005504 fatty acid binding(GO:0005504)
0.0 1.4 GO:0030332 cyclin binding(GO:0030332)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.4 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)