Motif ID: Hoxa6

Z-value: 0.677


Transcription factors associated with Hoxa6:

Gene SymbolEntrez IDGene Name
Hoxa6 ENSMUSG00000043219.8 Hoxa6



Activity profile for motif Hoxa6.

activity profile for motif Hoxa6


Sorted Z-values histogram for motif Hoxa6

Sorted Z-values for motif Hoxa6



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa6

PNG image of the network

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Top targets:


Showing 1 to 20 of 188 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_55681257 8.172 ENSMUST00000044767.8
 Neurod6
neurogenic differentiation 6
chr1_+_19103022 4.880 ENSMUST00000037294.7
 Tfap2d
transcription factor AP-2, delta
chr2_+_61804453 4.543 ENSMUST00000048934.8
 Tbr1
T-box brain gene 1
chr3_+_18054258 4.472 ENSMUST00000026120.6
 Bhlhe22
basic helix-loop-helix family, member e22
chr16_+_7069825 4.162 ENSMUST00000056416.7
 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr11_+_77930800 3.899 ENSMUST00000093995.3
ENSMUST00000000646.7
 Sez6

seizure related gene 6

chr8_-_84773381 3.723 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr1_+_177445660 3.302 ENSMUST00000077225.6
 Zbtb18
zinc finger and BTB domain containing 18
chr14_+_75455957 3.077 ENSMUST00000164848.1
 Siah3
seven in absentia homolog 3 (Drosophila)
chr5_-_123141067 2.906 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
 AI480526


expressed sequence AI480526


chr4_-_110292719 2.731 ENSMUST00000106601.1
 Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr2_-_7395968 2.505 ENSMUST00000002176.6
 Celf2
CUGBP, Elav-like family member 2
chr12_+_29528382 2.195 ENSMUST00000049784.9
 Myt1l
myelin transcription factor 1-like
chr2_+_71528657 2.144 ENSMUST00000126400.1
 Dlx1
distal-less homeobox 1
chr4_-_110287479 2.144 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
 Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr1_+_177444653 2.084 ENSMUST00000094276.3
 Zbtb18
zinc finger and BTB domain containing 18
chr19_+_26605106 2.024 ENSMUST00000025862.7
ENSMUST00000176030.1
 Smarca2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chr8_+_54954728 2.018 ENSMUST00000033915.7
 Gpm6a
glycoprotein m6a
chr13_-_28953690 2.000 ENSMUST00000067230.5
 Sox4
SRY-box containing gene 4
chr4_+_13751297 1.914 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 9.0 GO:0021542 dentate gyrus development(GO:0021542)
0.2 7.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 5.2 GO:0021766 hippocampus development(GO:0021766)
0.1 4.9 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 4.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.9 4.5 GO:0001661 conditioned taste aversion(GO:0001661)
0.7 4.5 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.5 4.2 GO:0071420 cellular response to histamine(GO:0071420)
0.3 3.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3 3.5 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 3.5 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 3.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.1 3.2 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.6 3.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 2.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.4 2.2 GO:0072318 clathrin coat disassembly(GO:0072318)
0.7 2.1 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.4 2.1 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.2 2.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 2.1 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.4 GO:0045171 intercellular bridge(GO:0045171)
0.4 4.9 GO:0042788 polysomal ribosome(GO:0042788)
0.0 4.3 GO:0005802 trans-Golgi network(GO:0005802)
0.2 4.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 3.9 GO:0097440 apical dendrite(GO:0097440)
0.1 2.1 GO:0071564 npBAF complex(GO:0071564)
0.0 2.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.8 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.4 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 1.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.3 1.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 1.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 1.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.8 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.9 GO:0017091 AU-rich element binding(GO:0017091)
0.0 4.7 GO:0003729 mRNA binding(GO:0003729)
0.1 4.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 4.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 3.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 2.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 2.2 GO:0017124 SH3 domain binding(GO:0017124)
0.2 2.1 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 1.8 GO:0005262 calcium channel activity(GO:0005262)
0.4 1.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 1.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 1.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.5 1.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 1.3 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 1.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 1.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 1.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)