Motif ID: Hoxa9_Hoxb9

Z-value: 0.450

Transcription factors associated with Hoxa9_Hoxb9:

Gene SymbolEntrez IDGene Name
Hoxa9 ENSMUSG00000038227.9 Hoxa9
Hoxb9 ENSMUSG00000020875.8 Hoxb9



Activity profile for motif Hoxa9_Hoxb9.

activity profile for motif Hoxa9_Hoxb9


Sorted Z-values histogram for motif Hoxa9_Hoxb9

Sorted Z-values for motif Hoxa9_Hoxb9



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa9_Hoxb9

PNG image of the network

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Top targets:


Showing 1 to 20 of 105 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_108591279 3.232 ENSMUST00000051145.8
ENSMUST00000139626.1
 Wdr47

WD repeat domain 47

chr1_+_194619815 2.691 ENSMUST00000027952.5
 Plxna2
plexin A2
chr6_+_49822710 1.601 ENSMUST00000031843.6
 Npy
neuropeptide Y
chr15_+_81936911 1.532 ENSMUST00000135663.1
 Csdc2
cold shock domain containing C2, RNA binding
chr11_-_79504078 1.446 ENSMUST00000164465.2
 Omg
oligodendrocyte myelin glycoprotein
chr2_+_22622183 1.354 ENSMUST00000028123.3
 Gad2
glutamic acid decarboxylase 2
chr15_+_81936753 1.344 ENSMUST00000038757.7
 Csdc2
cold shock domain containing C2, RNA binding
chr18_-_31447383 1.242 ENSMUST00000025110.3
 Syt4
synaptotagmin IV
chr17_-_91092715 1.156 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
 Nrxn1


neurexin I


chr8_+_93810832 1.054 ENSMUST00000034198.8
ENSMUST00000125716.1
 Gnao1

guanine nucleotide binding protein, alpha O

chr1_+_66386968 0.801 ENSMUST00000145419.1
 Map2
microtubule-associated protein 2
chr7_+_28277706 0.797 ENSMUST00000094651.2
 Eid2b
EP300 interacting inhibitor of differentiation 2B
chr4_+_144893127 0.787 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr2_-_31845925 0.775 ENSMUST00000028188.7
 Fibcd1
fibrinogen C domain containing 1
chr8_+_112570043 0.737 ENSMUST00000034225.6
ENSMUST00000118171.1
 Cntnap4

contactin associated protein-like 4

chr2_-_45112890 0.713 ENSMUST00000076836.6
 Zeb2
zinc finger E-box binding homeobox 2
chr3_+_32436376 0.704 ENSMUST00000108242.1
 Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr18_+_37400845 0.673 ENSMUST00000057228.1
 Pcdhb9
protocadherin beta 9
chr7_+_56050135 0.660 ENSMUST00000076226.6
 Herc2
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 2
chr5_-_73191848 0.655 ENSMUST00000176910.1
 Fryl
furry homolog-like (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.7 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 1.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.3 1.6 GO:0019732 antifungal humoral response(GO:0019732)
0.3 1.4 GO:0006538 glutamate catabolic process(GO:0006538)
0.1 1.4 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.2 1.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.2 1.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 1.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.8 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.8 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.2 0.7 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.7 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.7 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.7 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.7 GO:2000821 regulation of grooming behavior(GO:2000821)
0.1 0.6 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.6 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.2 0.5 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 0.5 GO:0007525 somatic muscle development(GO:0007525)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 1.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.6 GO:0043195 terminal bouton(GO:0043195)
0.0 1.4 GO:0060077 inhibitory synapse(GO:0060077)
0.1 1.2 GO:0031045 dense core granule(GO:0031045)
0.1 0.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 0.7 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 1.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 1.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 1.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 1.1 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 0.8 GO:0008061 chitin binding(GO:0008061)
0.1 0.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.8 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.7 GO:0032183 SUMO binding(GO:0032183)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.6 GO:0016595 NMDA glutamate receptor activity(GO:0004972) glutamate binding(GO:0016595)
0.1 0.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.4 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.4 GO:0015026 coreceptor activity(GO:0015026)