Motif ID: Hoxb13

Z-value: 0.689


Transcription factors associated with Hoxb13:

Gene SymbolEntrez IDGene Name
Hoxb13 ENSMUSG00000049604.3 Hoxb13



Activity profile for motif Hoxb13.

activity profile for motif Hoxb13


Sorted Z-values histogram for motif Hoxb13

Sorted Z-values for motif Hoxb13



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb13

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_120948480 2.795 ENSMUST00000070653.6
 Slc16a3
solute carrier family 16 (monocarboxylic acid transporters), member 3
chr5_-_28467093 2.449 ENSMUST00000002708.3
 Shh
sonic hedgehog
chr3_+_106034661 1.892 ENSMUST00000170669.2
 Gm4540
predicted gene 4540
chr12_+_33957645 1.890 ENSMUST00000049089.5
 Twist1
twist basic helix-loop-helix transcription factor 1
chr9_+_65890237 1.816 ENSMUST00000045802.6
 2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr3_-_150073620 1.733 ENSMUST00000057740.5
 Rpsa-ps10
ribosomal protein SA, pseudogene 10
chr3_+_134236483 1.688 ENSMUST00000181904.1
ENSMUST00000053048.9
 Cxxc4

CXXC finger 4

chr17_+_87635974 1.488 ENSMUST00000053577.8
 Epcam
epithelial cell adhesion molecule
chr9_+_58134017 1.403 ENSMUST00000134955.1
ENSMUST00000147134.1
ENSMUST00000170397.1
 Stra6


stimulated by retinoic acid gene 6


chr4_-_92191749 1.370 ENSMUST00000123179.1
 Gm12666
predicted gene 12666
chr3_-_49757257 1.346 ENSMUST00000035931.7
 Pcdh18
protocadherin 18
chr5_+_139543889 1.189 ENSMUST00000174792.1
ENSMUST00000031523.8
 Uncx

UNC homeobox

chr17_-_26095487 1.158 ENSMUST00000025007.5
 Nme4
NME/NM23 nucleoside diphosphate kinase 4
chr15_-_83724979 1.127 ENSMUST00000171496.1
ENSMUST00000043634.5
ENSMUST00000076060.5
ENSMUST00000016907.7
 Scube1



signal peptide, CUB domain, EGF-like 1



chr12_+_79297345 1.108 ENSMUST00000079533.5
ENSMUST00000171210.1
 Rad51b

RAD51 homolog B

chr5_+_92809372 1.106 ENSMUST00000113054.2
 Shroom3
shroom family member 3
chr9_-_114781986 1.103 ENSMUST00000035009.8
ENSMUST00000084867.7
 Cmtm7

CKLF-like MARVEL transmembrane domain containing 7

chr9_+_108560422 1.103 ENSMUST00000081111.8
 Impdh2
inosine 5'-phosphate dehydrogenase 2
chr17_+_27556613 1.097 ENSMUST00000117600.1
ENSMUST00000114888.3
 Hmga1

high mobility group AT-hook 1

chr19_+_24875679 1.079 ENSMUST00000073080.5
 Gm10053
predicted gene 10053

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 308 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.4 GO:0006284 base-excision repair(GO:0006284)
0.6 3.3 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.2 3.2 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 2.5 GO:0009060 aerobic respiration(GO:0009060)
0.8 2.4 GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) kidney smooth muscle tissue development(GO:0072194) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.2 2.4 GO:0019985 translesion synthesis(GO:0019985)
0.2 2.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 2.1 GO:0098780 mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)
0.5 1.9 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 1.9 GO:0032543 mitochondrial translation(GO:0032543)
0.6 1.7 GO:0006597 spermine biosynthetic process(GO:0006597)
0.3 1.7 GO:0006177 GMP biosynthetic process(GO:0006177)
0.3 1.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 1.6 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 1.6 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.4 1.4 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.3 1.4 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.1 1.4 GO:0010388 cullin deneddylation(GO:0010388)
0.1 1.3 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.1 1.3 GO:0051451 myoblast migration(GO:0051451)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 147 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.6 GO:0016459 myosin complex(GO:0016459)
0.0 3.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.5 3.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 2.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 2.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 2.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 2.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.3 1.9 GO:0097452 GAIT complex(GO:0097452)
0.1 1.7 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1 1.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.6 GO:0008180 COP9 signalosome(GO:0008180)
0.3 1.5 GO:0008623 CHRAC(GO:0008623)
0.1 1.3 GO:0000243 commitment complex(GO:0000243)
0.0 1.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.3 GO:0030118 clathrin coat(GO:0030118)
0.4 1.2 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 1.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.2 1.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 210 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 3.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.2 3.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 2.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 2.6 GO:0003682 chromatin binding(GO:0003682)
0.0 2.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.5 2.4 GO:0005113 patched binding(GO:0005113)
0.1 2.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 2.1 GO:0030792 methylarsonite methyltransferase activity(GO:0030792)
0.1 2.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 2.0 GO:0051015 actin filament binding(GO:0051015)
0.6 1.9 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.6 1.9 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.4 1.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.4 1.7 GO:0019808 polyamine binding(GO:0019808)
0.1 1.7 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 1.7 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.2 1.6 GO:0000150 recombinase activity(GO:0000150)
0.1 1.6 GO:0016805 dipeptidase activity(GO:0016805)
0.2 1.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)