Motif ID: Hoxb3

Z-value: 1.298


Transcription factors associated with Hoxb3:

Gene SymbolEntrez IDGene Name
Hoxb3 ENSMUSG00000048763.5 Hoxb3



Activity profile for motif Hoxb3.

activity profile for motif Hoxb3


Sorted Z-values histogram for motif Hoxb3

Sorted Z-values for motif Hoxb3



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb3

PNG image of the network

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Top targets:


Showing 1 to 20 of 128 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_170009892 21.079 ENSMUST00000180251.1
 Gm21887
predicted gene, 21887
chr15_-_8710734 11.842 ENSMUST00000005493.7
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrY_+_90785442 11.810 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
 Erdr1


erythroid differentiation regulator 1


chr2_-_156392829 11.603 ENSMUST00000088578.2
 2900097C17Rik
RIKEN cDNA 2900097C17 gene
chr15_-_8710409 11.481 ENSMUST00000157065.1
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrY_+_90784738 7.109 ENSMUST00000179483.1
 Erdr1
erythroid differentiation regulator 1
chr5_-_84417359 7.070 ENSMUST00000113401.1
 Epha5
Eph receptor A5
chr12_+_74288735 7.026 ENSMUST00000095617.1
 1700086L19Rik
RIKEN cDNA 1700086L19 gene
chrX_+_170010744 6.672 ENSMUST00000178789.1
 Gm21887
predicted gene, 21887
chr16_-_52296924 5.953 ENSMUST00000167115.1
 Alcam
activated leukocyte cell adhesion molecule
chr9_-_54661870 5.854 ENSMUST00000034822.5
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr19_+_3323301 5.836 ENSMUST00000025835.4
 Cpt1a
carnitine palmitoyltransferase 1a, liver
chr12_+_84069325 5.834 ENSMUST00000046422.4
ENSMUST00000072505.4
 Acot5

acyl-CoA thioesterase 5

chr9_-_54661666 5.473 ENSMUST00000128624.1
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr12_-_24493656 5.333 ENSMUST00000073088.2
 Gm16372
predicted pseudogene 16372
chr5_+_63812447 4.991 ENSMUST00000081747.3
 0610040J01Rik
RIKEN cDNA 0610040J01 gene
chr12_+_16653470 4.871 ENSMUST00000111064.1
 Ntsr2
neurotensin receptor 2
chr10_-_83648631 4.497 ENSMUST00000146876.2
ENSMUST00000176294.1
 Appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

chr7_-_140154712 4.453 ENSMUST00000059241.7
 Sprn
shadow of prion protein
chr11_+_101665541 4.423 ENSMUST00000039388.2
 Arl4d
ADP-ribosylation factor-like 4D

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.8 23.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 15.6 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.4 12.8 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.7 7.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 6.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
1.5 5.8 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.5 5.8 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.4 5.7 GO:0034501 protein localization to kinetochore(GO:0034501)
0.8 5.3 GO:0019532 oxalate transport(GO:0019532)
0.1 4.9 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.6 3.9 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 3.9 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.3 3.8 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 3.6 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 3.6 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 3.4 GO:0098792 xenophagy(GO:0098792)
0.4 3.1 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 2.8 GO:0006665 sphingolipid metabolic process(GO:0006665)
0.9 2.7 GO:0019085 early viral transcription(GO:0019085)
0.9 2.7 GO:1902498 regulation of protein autoubiquitination(GO:1902498)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 23.3 GO:0043205 fibril(GO:0043205)
0.1 18.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 7.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.4 6.0 GO:0042101 T cell receptor complex(GO:0042101)
0.2 5.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 5.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 4.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 4.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 3.9 GO:0044295 axonal growth cone(GO:0044295)
0.2 3.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 3.6 GO:0031902 late endosome membrane(GO:0031902)
0.0 3.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 3.1 GO:0055037 recycling endosome(GO:0055037)
0.2 2.5 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 2.4 GO:0043198 dendritic shaft(GO:0043198)
0.1 1.7 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 1.7 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 1.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.6 GO:0005884 actin filament(GO:0005884)
0.0 1.5 GO:0070469 respiratory chain(GO:0070469)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.7 23.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
1.0 11.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.9 7.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
1.2 5.8 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.4 5.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 5.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.5 5.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 5.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.3 4.9 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 4.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 3.8 GO:0005262 calcium channel activity(GO:0005262)
0.1 3.6 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.4 3.1 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 3.0 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.5 2.8 GO:0017040 ceramidase activity(GO:0017040)
0.3 2.7 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 2.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 2.7 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.3 2.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 2.3 GO:0070412 R-SMAD binding(GO:0070412)