Motif ID: Hoxb4

Z-value: 0.348


Transcription factors associated with Hoxb4:

Gene SymbolEntrez IDGene Name
Hoxb4 ENSMUSG00000038692.7 Hoxb4



Activity profile for motif Hoxb4.

activity profile for motif Hoxb4


Sorted Z-values histogram for motif Hoxb4

Sorted Z-values for motif Hoxb4



Network of associatons between targets according to the STRING database.


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_143933204 2.211 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
 Dcx


doublecortin


chr12_+_58211772 1.341 ENSMUST00000110671.2
ENSMUST00000044299.2
 Sstr1

somatostatin receptor 1

chrX_-_143933089 1.254 ENSMUST00000087313.3
 Dcx
doublecortin
chrX_+_166344692 1.108 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
 Gpm6b





glycoprotein m6b





chr1_-_52490736 0.997 ENSMUST00000170269.1
 Nab1
Ngfi-A binding protein 1
chr16_+_78930940 0.913 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
 Chodl


chondrolectin


chr1_+_159737510 0.665 ENSMUST00000111669.3
 Tnr
tenascin R
chr12_-_15816762 0.609 ENSMUST00000020922.7
 Trib2
tribbles homolog 2 (Drosophila)
chr4_+_43493345 0.563 ENSMUST00000030181.5
ENSMUST00000107922.2
 Ccdc107

coiled-coil domain containing 107

chr10_-_92162753 0.493 ENSMUST00000182197.1
 Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr10_-_88605017 0.439 ENSMUST00000119185.1
ENSMUST00000121629.1
 Mybpc1

myosin binding protein C, slow-type

chr3_-_54714353 0.422 ENSMUST00000178832.1
 Gm21958
predicted gene, 21958
chr8_+_25808474 0.384 ENSMUST00000033979.4
 Star
steroidogenic acute regulatory protein
chr16_-_94370450 0.370 ENSMUST00000138514.1
 Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr8_+_83666827 0.346 ENSMUST00000019608.5
 Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr11_+_85353156 0.330 ENSMUST00000108061.1
ENSMUST00000108062.1
ENSMUST00000108056.1
ENSMUST00000138423.1
ENSMUST00000074875.4
ENSMUST00000092821.3
 Bcas3





breast carcinoma amplified sequence 3





chr3_-_37125943 0.304 ENSMUST00000029275.5
 Il2
interleukin 2
chr1_+_146497614 0.248 ENSMUST00000132847.1
ENSMUST00000166814.1
 Brinp3

bone morphogenetic protein/retinoic acid inducible neural specific 3

chr17_+_43952999 0.242 ENSMUST00000177857.1
 Rcan2
regulator of calcineurin 2
chr10_-_89621253 0.227 ENSMUST00000020102.7
 Slc17a8
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
chr1_+_10993452 0.193 ENSMUST00000027056.5
 Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr11_-_40755201 0.161 ENSMUST00000020576.7
 Ccng1
cyclin G1
chr19_+_4711153 0.118 ENSMUST00000008991.6
 Sptbn2
spectrin beta, non-erythrocytic 2
chr2_-_84775388 0.102 ENSMUST00000023994.3
 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr15_-_50889691 0.095 ENSMUST00000165201.2
ENSMUST00000184458.1
 Trps1

trichorhinophalangeal syndrome I (human)

chr17_+_86963279 0.077 ENSMUST00000139344.1
 Rhoq
ras homolog gene family, member Q
chr1_-_171222435 0.074 ENSMUST00000147246.1
ENSMUST00000111326.1
ENSMUST00000138184.1
 Tomm40l


translocase of outer mitochondrial membrane 40 homolog-like (yeast)


chr5_+_143363890 0.065 ENSMUST00000010969.8
 Grid2ip
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1
chr2_-_84775420 0.065 ENSMUST00000111641.1
 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr7_-_30232186 0.056 ENSMUST00000006254.5
 Tbcb
tubulin folding cofactor B
chr1_-_171222508 0.023 ENSMUST00000005817.2
 Tomm40l
translocase of outer mitochondrial membrane 40 homolog-like (yeast)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.2 3.5 GO:0021860 pyramidal neuron development(GO:0021860)
0.2 1.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013) positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 1.3 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.2 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 0.6 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.1 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.3 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 1.0 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.2 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0072534 perineuronal net(GO:0072534)
0.1 0.2 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.4 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 3.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.3 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.1 1.0 GO:0046625 sphingolipid binding(GO:0046625)
0.1 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.6 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.4 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 0.2 GO:0001848 complement binding(GO:0001848)