Motif ID: Hoxb8_Pdx1
Z-value: 0.816
Transcription factors associated with Hoxb8_Pdx1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hoxb8 | ENSMUSG00000056648.4 | Hoxb8 |
Pdx1 | ENSMUSG00000029644.6 | Pdx1 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.5 | GO:0003345 | proepicardium cell migration involved in pericardium morphogenesis(GO:0003345) |
0.5 | 4.6 | GO:0060373 | regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
0.5 | 2.0 | GO:0031622 | positive regulation of fever generation(GO:0031622) |
0.4 | 1.7 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
0.4 | 7.0 | GO:0021860 | pyramidal neuron development(GO:0021860) |
0.3 | 4.9 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.3 | 0.8 | GO:0007181 | transforming growth factor beta receptor complex assembly(GO:0007181) |
0.2 | 1.4 | GO:0032790 | ribosome disassembly(GO:0032790) |
0.2 | 0.8 | GO:0055095 | lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) |
0.2 | 0.4 | GO:0006953 | acute-phase response(GO:0006953) |
0.2 | 2.0 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
0.2 | 1.3 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) |
0.2 | 2.6 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
0.2 | 0.6 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) positive regulation of isotype switching to IgG isotypes(GO:0048304) |
0.1 | 3.7 | GO:0021692 | cerebellar Purkinje cell layer morphogenesis(GO:0021692) |
0.1 | 0.4 | GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) |
0.1 | 0.5 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
0.1 | 1.2 | GO:0060346 | bone trabecula formation(GO:0060346) |
0.1 | 2.2 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
0.1 | 1.0 | GO:0032625 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
0.1 | 0.4 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
0.1 | 0.6 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
0.1 | 1.0 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
0.1 | 2.5 | GO:2000060 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060) |
0.1 | 1.9 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.1 | 0.3 | GO:0097623 | potassium ion export across plasma membrane(GO:0097623) |
0.1 | 0.3 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
0.1 | 0.3 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
0.1 | 0.3 | GO:0031509 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
0.1 | 0.7 | GO:0050908 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
0.1 | 0.2 | GO:0051030 | snRNA transport(GO:0051030) |
0.1 | 0.6 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
0.1 | 0.3 | GO:0050913 | sensory perception of bitter taste(GO:0050913) |
0.1 | 0.5 | GO:0051013 | microtubule severing(GO:0051013) |
0.1 | 0.4 | GO:0018377 | N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377) |
0.1 | 0.7 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) regulation of membrane depolarization during action potential(GO:0098902) regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
0.1 | 0.4 | GO:0035743 | CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745) |
0.1 | 0.6 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
0.1 | 0.9 | GO:1901741 | positive regulation of myoblast fusion(GO:1901741) |
0.1 | 1.5 | GO:0006491 | N-glycan processing(GO:0006491) |
0.1 | 0.2 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
0.1 | 0.3 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
0.1 | 0.3 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
0.1 | 1.0 | GO:0090140 | regulation of mitochondrial fission(GO:0090140) |
0.1 | 0.2 | GO:0051026 | chiasma assembly(GO:0051026) |
0.1 | 0.6 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
0.0 | 0.9 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
0.0 | 0.4 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
0.0 | 0.2 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
0.0 | 0.2 | GO:0046294 | formaldehyde catabolic process(GO:0046294) |
0.0 | 0.7 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
0.0 | 0.2 | GO:0051661 | maintenance of centrosome location(GO:0051661) regulation of microtubule motor activity(GO:2000574) |
0.0 | 0.3 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
0.0 | 0.3 | GO:0060484 | lung-associated mesenchyme development(GO:0060484) |
0.0 | 0.8 | GO:0007614 | short-term memory(GO:0007614) |
0.0 | 0.3 | GO:0033599 | regulation of mammary gland epithelial cell proliferation(GO:0033599) |
0.0 | 0.3 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
0.0 | 2.6 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 0.9 | GO:0007617 | mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705) |
0.0 | 2.8 | GO:0030032 | lamellipodium assembly(GO:0030032) |
0.0 | 0.3 | GO:0060837 | blood vessel endothelial cell differentiation(GO:0060837) |
0.0 | 0.2 | GO:0002361 | CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) |
0.0 | 1.1 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
0.0 | 1.2 | GO:1902668 | negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668) |
0.0 | 0.2 | GO:0032693 | negative regulation of interleukin-10 production(GO:0032693) |
0.0 | 2.1 | GO:0030279 | negative regulation of ossification(GO:0030279) |
0.0 | 0.5 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.0 | 0.4 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
0.0 | 0.2 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
0.0 | 0.2 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
0.0 | 0.1 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
0.0 | 0.3 | GO:0070102 | interleukin-6-mediated signaling pathway(GO:0070102) |
0.0 | 0.1 | GO:0043987 | histone H3-S10 phosphorylation(GO:0043987) |
0.0 | 1.6 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.0 | 0.1 | GO:1902474 | positive regulation of protein localization to synapse(GO:1902474) |
0.0 | 0.1 | GO:1904059 | regulation of eating behavior(GO:1903998) regulation of locomotor rhythm(GO:1904059) |
0.0 | 0.4 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
0.0 | 0.1 | GO:2000642 | negative regulation of early endosome to late endosome transport(GO:2000642) |
0.0 | 0.4 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
0.0 | 0.2 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
0.0 | 0.2 | GO:0006012 | galactose metabolic process(GO:0006012) |
0.0 | 0.1 | GO:0000957 | mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) |
0.0 | 0.6 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
0.0 | 0.1 | GO:0035633 | maintenance of blood-brain barrier(GO:0035633) |
0.0 | 0.5 | GO:0071625 | vocalization behavior(GO:0071625) |
0.0 | 0.2 | GO:2000465 | regulation of glycogen (starch) synthase activity(GO:2000465) |
0.0 | 0.7 | GO:0007528 | neuromuscular junction development(GO:0007528) |
0.0 | 0.3 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
0.0 | 0.7 | GO:0060612 | adipose tissue development(GO:0060612) |
0.0 | 0.3 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.0 | 0.2 | GO:0070842 | aggresome assembly(GO:0070842) |
0.0 | 0.1 | GO:0006968 | cellular defense response(GO:0006968) |
0.0 | 0.4 | GO:0030488 | tRNA methylation(GO:0030488) |
0.0 | 0.4 | GO:0032496 | response to lipopolysaccharide(GO:0032496) |
0.0 | 0.2 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
0.0 | 1.1 | GO:0007286 | spermatid development(GO:0007286) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 3.7 | GO:0008091 | spectrin(GO:0008091) |
0.3 | 0.8 | GO:0048179 | activin receptor complex(GO:0048179) |
0.3 | 4.4 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
0.2 | 2.4 | GO:0045298 | tubulin complex(GO:0045298) |
0.1 | 0.3 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.1 | 1.7 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.1 | 0.4 | GO:0097361 | CIA complex(GO:0097361) |
0.1 | 1.1 | GO:0005869 | dynactin complex(GO:0005869) |
0.1 | 0.5 | GO:0005638 | lamin filament(GO:0005638) |
0.1 | 0.5 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
0.1 | 0.7 | GO:0043083 | synaptic cleft(GO:0043083) |
0.1 | 2.0 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.1 | 6.0 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.1 | 0.6 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
0.1 | 1.9 | GO:0043034 | costamere(GO:0043034) |
0.1 | 2.5 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 0.3 | GO:0001740 | Barr body(GO:0001740) |
0.0 | 0.7 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.0 | 0.6 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.0 | 0.3 | GO:0000439 | core TFIIH complex(GO:0000439) |
0.0 | 0.2 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
0.0 | 0.3 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
0.0 | 0.7 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 1.6 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 0.2 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.0 | 0.2 | GO:0000235 | astral microtubule(GO:0000235) |
0.0 | 0.4 | GO:0042405 | nuclear inclusion body(GO:0042405) |
0.0 | 2.8 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.0 | 0.2 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
0.0 | 0.2 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
0.0 | 0.3 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
0.0 | 0.5 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
0.0 | 2.2 | GO:0070382 | exocytic vesicle(GO:0070382) |
0.0 | 0.1 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.0 | 0.2 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
0.0 | 0.4 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.0 | 1.7 | GO:0005814 | centriole(GO:0005814) |
0.0 | 0.3 | GO:0098687 | chromosomal region(GO:0098687) |
0.0 | 0.3 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.0 | 0.5 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
0.0 | 0.7 | GO:0030315 | T-tubule(GO:0030315) |
0.0 | 2.0 | GO:0030426 | growth cone(GO:0030426) |
0.0 | 1.8 | GO:0043679 | axon terminus(GO:0043679) |
0.0 | 0.7 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.0 | 0.4 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 0.4 | GO:0031902 | late endosome membrane(GO:0031902) |
0.0 | 0.6 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 5.7 | GO:0030425 | dendrite(GO:0030425) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 2.6 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
0.7 | 4.6 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
0.6 | 1.7 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
0.5 | 2.0 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
0.4 | 1.3 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
0.4 | 1.8 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
0.3 | 2.0 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
0.3 | 7.0 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.2 | 0.8 | GO:0016361 | activin receptor activity, type I(GO:0016361) |
0.1 | 0.6 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
0.1 | 2.7 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.1 | 0.6 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
0.1 | 1.4 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.1 | 0.3 | GO:1902282 | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282) |
0.1 | 2.8 | GO:0071813 | lipoprotein particle binding(GO:0071813) protein-lipid complex binding(GO:0071814) |
0.1 | 2.2 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
0.1 | 1.9 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
0.1 | 0.6 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
0.1 | 0.7 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
0.1 | 0.2 | GO:0004335 | galactokinase activity(GO:0004335) |
0.1 | 0.5 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.1 | 0.3 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
0.1 | 0.2 | GO:0018738 | S-formylglutathione hydrolase activity(GO:0018738) |
0.1 | 0.3 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
0.1 | 0.3 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.1 | 3.6 | GO:0005179 | hormone activity(GO:0005179) |
0.1 | 0.6 | GO:0017127 | cholesterol transporter activity(GO:0017127) |
0.0 | 0.2 | GO:2001069 | glycogen binding(GO:2001069) |
0.0 | 1.7 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.0 | 0.7 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
0.0 | 0.2 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
0.0 | 0.2 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.0 | 0.5 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.0 | 0.7 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 0.3 | GO:0000182 | rDNA binding(GO:0000182) |
0.0 | 0.4 | GO:0050072 | m7G(5')pppN diphosphatase activity(GO:0050072) |
0.0 | 2.1 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.0 | 0.3 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
0.0 | 0.2 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) |
0.0 | 1.2 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.2 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
0.0 | 0.1 | GO:0035175 | histone kinase activity (H3-S10 specific)(GO:0035175) |
0.0 | 0.1 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.0 | 1.0 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.0 | 0.2 | GO:0015643 | toxic substance binding(GO:0015643) |
0.0 | 0.2 | GO:0030983 | mismatched DNA binding(GO:0030983) |
0.0 | 0.5 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
0.0 | 0.2 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.0 | 0.2 | GO:0003958 | NADPH-hemoprotein reductase activity(GO:0003958) |
0.0 | 0.7 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.0 | 0.3 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.0 | 0.2 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
0.0 | 0.3 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.0 | 0.4 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.0 | 0.4 | GO:0034946 | 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466) |
0.0 | 0.1 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
0.0 | 0.3 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.0 | 0.4 | GO:0042287 | MHC protein binding(GO:0042287) |
0.0 | 0.1 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
0.0 | 0.2 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.0 | 1.2 | GO:0005496 | steroid binding(GO:0005496) |
0.0 | 2.0 | GO:0008144 | drug binding(GO:0008144) |
0.0 | 0.4 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
0.0 | 0.7 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
0.0 | 0.9 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.0 | 0.2 | GO:0032552 | pyrimidine nucleotide binding(GO:0019103) deoxyribonucleotide binding(GO:0032552) |
0.0 | 0.2 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
0.0 | 1.4 | GO:0008201 | heparin binding(GO:0008201) |
0.0 | 0.1 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
0.0 | 0.3 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |