Motif ID: Hoxd10

Z-value: 0.528


Transcription factors associated with Hoxd10:

Gene SymbolEntrez IDGene Name
Hoxd10 ENSMUSG00000050368.3 Hoxd10



Activity profile for motif Hoxd10.

activity profile for motif Hoxd10


Sorted Z-values histogram for motif Hoxd10

Sorted Z-values for motif Hoxd10



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd10

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_84773381 6.986 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr9_+_27790947 5.197 ENSMUST00000115243.2
 Opcml
opioid binding protein/cell adhesion molecule-like
chr3_-_80802789 4.850 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr4_+_102254993 2.741 ENSMUST00000106908.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chrX_+_66653003 2.462 ENSMUST00000036043.4
 Slitrk2
SLIT and NTRK-like family, member 2
chr3_+_55461758 1.927 ENSMUST00000070418.4
 Dclk1
doublecortin-like kinase 1
chrX_-_70365052 1.682 ENSMUST00000101509.2
 Ids
iduronate 2-sulfatase
chr18_-_78123324 1.682 ENSMUST00000160292.1
ENSMUST00000091813.5
 Slc14a1

solute carrier family 14 (urea transporter), member 1

chr15_+_9140527 1.295 ENSMUST00000090380.4
 Lmbrd2
LMBR1 domain containing 2
chr7_+_30095150 1.273 ENSMUST00000130526.1
ENSMUST00000108200.1
 Zfp260

zinc finger protein 260

chr17_+_78508063 1.240 ENSMUST00000024880.9
 Vit
vitrin
chr8_-_109251698 1.083 ENSMUST00000079189.3
 4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr13_-_71963713 1.080 ENSMUST00000077337.8
 Irx1
Iroquois related homeobox 1 (Drosophila)
chr7_+_96210107 1.075 ENSMUST00000138760.1
 Tenm4
teneurin transmembrane protein 4
chr2_+_21367532 1.068 ENSMUST00000055946.7
 Gpr158
G protein-coupled receptor 158
chr10_-_49783259 1.006 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
 Grik2



glutamate receptor, ionotropic, kainate 2 (beta 2)



chr9_+_95857597 0.931 ENSMUST00000034980.7
 Atr
ataxia telangiectasia and Rad3 related
chr6_-_28397999 0.887 ENSMUST00000035930.4
 Zfp800
zinc finger protein 800
chr2_+_65620829 0.862 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr7_-_73541738 0.741 ENSMUST00000169922.2
 Chd2
chromodomain helicase DNA binding protein 2
chr2_+_106693185 0.738 ENSMUST00000111063.1
 Mpped2
metallophosphoesterase domain containing 2
chr3_+_86084434 0.627 ENSMUST00000107664.2
 Sh3d19
SH3 domain protein D19
chr14_-_93888732 0.622 ENSMUST00000068992.2
 Pcdh9
protocadherin 9
chr15_+_57912199 0.610 ENSMUST00000022992.6
 Tbc1d31
TBC1 domain family, member 31
chr1_+_180111339 0.597 ENSMUST00000145181.1
 Cdc42bpa
CDC42 binding protein kinase alpha
chr6_+_33249085 0.548 ENSMUST00000052266.8
ENSMUST00000090381.4
ENSMUST00000115080.1
 Exoc4


exocyst complex component 4


chr18_-_6490808 0.507 ENSMUST00000028100.6
ENSMUST00000050542.5
 Epc1

enhancer of polycomb homolog 1 (Drosophila)

chr17_-_46327949 0.437 ENSMUST00000047970.7
 Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr12_+_76417598 0.433 ENSMUST00000063977.7
 Ppp1r36
protein phosphatase 1, regulatory subunit 36
chr13_+_49582745 0.416 ENSMUST00000065494.7
 Omd
osteomodulin
chr9_+_104569671 0.403 ENSMUST00000057742.8
 Cpne4
copine IV
chr4_+_19605451 0.348 ENSMUST00000108250.2
 Gm12353
predicted gene 12353
chr14_-_87141114 0.338 ENSMUST00000168889.1
 Diap3
diaphanous homolog 3 (Drosophila)
chr10_+_116177351 0.318 ENSMUST00000155606.1
ENSMUST00000128399.1
 Ptprr

protein tyrosine phosphatase, receptor type, R

chr17_-_78684262 0.208 ENSMUST00000145480.1
 Strn
striatin, calmodulin binding protein
chr10_+_69534039 0.199 ENSMUST00000182557.1
 Ank3
ankyrin 3, epithelial
chr14_+_79515618 0.163 ENSMUST00000110835.1
 Elf1
E74-like factor 1
chr12_+_55089202 0.153 ENSMUST00000021407.10
 Srp54a
signal recognition particle 54A
chr2_-_174464063 0.108 ENSMUST00000016396.7
 Atp5e
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
chr1_-_152625212 0.090 ENSMUST00000027760.7
 Rgl1
ral guanine nucleotide dissociation stimulator,-like 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3 0.9 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.3 1.1 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.2 1.7 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.2 4.9 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 0.9 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2 2.7 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.0 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.5 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.7 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 1.9 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.6 GO:0007097 nuclear migration(GO:0007097)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.9 GO:0032279 asymmetric synapse(GO:0032279)
0.2 1.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 2.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.9 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.5 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.9 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.1 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.9 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.3 1.7 GO:0015265 urea channel activity(GO:0015265)
0.2 0.9 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.1 1.7 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 2.7 GO:0030552 cAMP binding(GO:0030552)
0.1 0.9 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.7 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)