Motif ID: Hoxd10

Z-value: 0.528


Transcription factors associated with Hoxd10:

Gene SymbolEntrez IDGene Name
Hoxd10 ENSMUSG00000050368.3 Hoxd10



Activity profile for motif Hoxd10.

activity profile for motif Hoxd10


Sorted Z-values histogram for motif Hoxd10

Sorted Z-values for motif Hoxd10



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd10

PNG image of the network

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Top targets:


Showing 1 to 20 of 40 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84773381 6.986 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr9_+_27790947 5.197 ENSMUST00000115243.2
 Opcml
opioid binding protein/cell adhesion molecule-like
chr3_-_80802789 4.850 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr4_+_102254993 2.741 ENSMUST00000106908.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chrX_+_66653003 2.462 ENSMUST00000036043.4
 Slitrk2
SLIT and NTRK-like family, member 2
chr3_+_55461758 1.927 ENSMUST00000070418.4
 Dclk1
doublecortin-like kinase 1
chrX_-_70365052 1.682 ENSMUST00000101509.2
 Ids
iduronate 2-sulfatase
chr18_-_78123324 1.682 ENSMUST00000160292.1
ENSMUST00000091813.5
 Slc14a1

solute carrier family 14 (urea transporter), member 1

chr15_+_9140527 1.295 ENSMUST00000090380.4
 Lmbrd2
LMBR1 domain containing 2
chr7_+_30095150 1.273 ENSMUST00000130526.1
ENSMUST00000108200.1
 Zfp260

zinc finger protein 260

chr17_+_78508063 1.240 ENSMUST00000024880.9
 Vit
vitrin
chr8_-_109251698 1.083 ENSMUST00000079189.3
 4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr13_-_71963713 1.080 ENSMUST00000077337.8
 Irx1
Iroquois related homeobox 1 (Drosophila)
chr7_+_96210107 1.075 ENSMUST00000138760.1
 Tenm4
teneurin transmembrane protein 4
chr2_+_21367532 1.068 ENSMUST00000055946.7
 Gpr158
G protein-coupled receptor 158
chr10_-_49783259 1.006 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
 Grik2



glutamate receptor, ionotropic, kainate 2 (beta 2)



chr9_+_95857597 0.931 ENSMUST00000034980.7
 Atr
ataxia telangiectasia and Rad3 related
chr6_-_28397999 0.887 ENSMUST00000035930.4
 Zfp800
zinc finger protein 800
chr2_+_65620829 0.862 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr7_-_73541738 0.741 ENSMUST00000169922.2
 Chd2
chromodomain helicase DNA binding protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 7.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 4.9 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 2.7 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 1.9 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 1.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 1.7 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.3 1.1 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.1 1.0 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.3 0.9 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.2 0.9 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.7 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.6 GO:0007097 nuclear migration(GO:0007097)
0.1 0.5 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.9 GO:0032279 asymmetric synapse(GO:0032279)
0.1 2.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.9 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.9 GO:0001741 XY body(GO:0001741)
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.5 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)

Gene overrepresentation in molecular_function category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 5.9 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 2.7 GO:0030552 cAMP binding(GO:0030552)
0.3 1.7 GO:0015265 urea channel activity(GO:0015265)
0.1 1.7 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.2 0.9 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.1 0.9 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.7 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)