Motif ID: Hoxd9

Z-value: 0.734


Transcription factors associated with Hoxd9:

Gene SymbolEntrez IDGene Name
Hoxd9 ENSMUSG00000043342.8 Hoxd9



Activity profile for motif Hoxd9.

activity profile for motif Hoxd9


Sorted Z-values histogram for motif Hoxd9

Sorted Z-values for motif Hoxd9



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd9

PNG image of the network

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Top targets:


Showing 1 to 20 of 96 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_-_78206408 4.350 ENSMUST00000163367.1
 Slc14a2
solute carrier family 14 (urea transporter), member 2
chr6_-_36811361 3.433 ENSMUST00000101534.1
 Ptn
pleiotrophin
chr15_-_37459327 3.356 ENSMUST00000119730.1
ENSMUST00000120746.1
 Ncald

neurocalcin delta

chrX_+_82948861 3.242 ENSMUST00000114000.1
 Dmd
dystrophin, muscular dystrophy
chr5_-_62766153 3.163 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr13_-_105271039 3.161 ENSMUST00000069686.6
 Rnf180
ring finger protein 180
chr12_+_38783503 3.035 ENSMUST00000159334.1
 Etv1
ets variant gene 1
chr13_-_41273977 2.943 ENSMUST00000163881.1
 Gm17364
predicted gene, 17364
chr3_-_116129615 2.835 ENSMUST00000029574.8
 Vcam1
vascular cell adhesion molecule 1
chr4_+_136143497 2.754 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chr11_+_29373618 2.722 ENSMUST00000040182.6
ENSMUST00000109477.1
 Ccdc88a

coiled coil domain containing 88A

chr11_-_109472611 2.608 ENSMUST00000168740.1
 Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr2_-_84425258 2.537 ENSMUST00000074262.2
 Calcrl
calcitonin receptor-like
chr19_+_23723279 2.311 ENSMUST00000067077.1
 Gm9938
predicted gene 9938
chr2_-_63184253 2.245 ENSMUST00000075052.3
ENSMUST00000112454.1
 Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr3_-_66296807 2.087 ENSMUST00000029419.7
 Veph1
ventricular zone expressed PH domain-containing 1
chr5_-_77408034 1.950 ENSMUST00000163898.1
ENSMUST00000046746.6
 Igfbp7

insulin-like growth factor binding protein 7

chr1_+_167598450 1.950 ENSMUST00000111386.1
ENSMUST00000111384.1
 Rxrg

retinoid X receptor gamma

chr11_+_110968016 1.929 ENSMUST00000106636.1
ENSMUST00000180023.1
 Kcnj16

potassium inwardly-rectifying channel, subfamily J, member 16

chr1_-_175491130 1.912 ENSMUST00000027812.5
 Rgs7
regulator of G protein signaling 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 5.0 GO:0008065 establishment of blood-nerve barrier(GO:0008065) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.6 4.3 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
1.1 3.4 GO:1904395 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 3.4 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 3.4 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.3 3.2 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.1 3.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.3 2.8 GO:0061032 visceral serous pericardium development(GO:0061032)
0.1 2.8 GO:0071398 cellular response to fatty acid(GO:0071398)
0.1 2.8 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 2.7 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.1 2.6 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.6 2.5 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 1.9 GO:0050810 regulation of steroid biosynthetic process(GO:0050810)
0.0 1.9 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 1.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 1.3 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 1.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 1.1 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.1 1.0 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 6.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 4.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 3.2 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.1 2.8 GO:0002102 podosome(GO:0002102)
0.1 1.9 GO:0044292 dendrite terminus(GO:0044292)
0.1 1.0 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.9 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.9 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 0.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.7 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.5 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.3 GO:0071438 NADPH oxidase complex(GO:0043020) invadopodium membrane(GO:0071438)
0.0 0.3 GO:0032580 Golgi cisterna membrane(GO:0032580)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 5.0 GO:0017166 dystroglycan binding(GO:0002162) vinculin binding(GO:0017166)
0.1 4.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.7 4.3 GO:0015265 urea channel activity(GO:0015265)
0.2 4.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
1.1 3.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 3.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 3.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.3 3.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.7 2.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 2.8 GO:0005504 fatty acid binding(GO:0005504)
0.1 2.7 GO:0043422 protein kinase B binding(GO:0043422)
0.2 2.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.6 2.5 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 1.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 1.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 1.2 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 1.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 1.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 1.0 GO:0042287 MHC protein binding(GO:0042287)