Motif ID: Hsf1

Z-value: 0.684


Transcription factors associated with Hsf1:

Gene SymbolEntrez IDGene Name
Hsf1 ENSMUSG00000022556.9 Hsf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hsf1mm10_v2_chr15_+_76477404_764774610.106.0e-01Click!


Activity profile for motif Hsf1.

activity profile for motif Hsf1


Sorted Z-values histogram for motif Hsf1

Sorted Z-values for motif Hsf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hsf1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_48667508 6.339 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
 Otx2



orthodenticle homolog 2 (Drosophila)



chr6_-_128438673 4.040 ENSMUST00000032508.4
 Fkbp4
FK506 binding protein 4
chr9_+_40801235 3.961 ENSMUST00000117870.1
ENSMUST00000117557.1
 Hspa8

heat shock protein 8

chr5_-_149636164 3.808 ENSMUST00000076410.4
 Hsph1
heat shock 105kDa/110kDa protein 1
chr19_-_7039987 3.415 ENSMUST00000025918.7
 Stip1
stress-induced phosphoprotein 1
chr7_-_99353104 2.792 ENSMUST00000169437.1
ENSMUST00000094154.4
 Serpinh1

serine (or cysteine) peptidase inhibitor, clade H, member 1

chrX_+_71663665 2.639 ENSMUST00000070449.5
 Gpr50
G-protein-coupled receptor 50
chr2_+_120463566 2.475 ENSMUST00000028749.7
ENSMUST00000110721.1
 Capn3

calpain 3

chr5_-_149636331 2.382 ENSMUST00000074846.7
ENSMUST00000110498.1
ENSMUST00000127977.1
ENSMUST00000132412.1
 Hsph1



heat shock 105kDa/110kDa protein 1



chr12_+_117843873 2.137 ENSMUST00000176735.1
ENSMUST00000177339.1
 Cdca7l

cell division cycle associated 7 like

chr15_-_31601506 2.116 ENSMUST00000161266.1
 Cct5
chaperonin containing Tcp1, subunit 5 (epsilon)
chr17_-_45572495 2.059 ENSMUST00000130406.1
 Hsp90ab1
heat shock protein 90 alpha (cytosolic), class B member 1
chr7_-_70366735 1.977 ENSMUST00000089565.5
 Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr6_+_128438757 1.931 ENSMUST00000144745.1
 Gm10069
predicted gene 10069
chr11_-_116843449 1.780 ENSMUST00000047616.3
 Jmjd6
jumonji domain containing 6
chr11_+_22990519 1.714 ENSMUST00000173867.1
ENSMUST00000020562.4
 Cct4

chaperonin containing Tcp1, subunit 4 (delta)

chr11_+_49609263 1.612 ENSMUST00000020617.2
 Flt4
FMS-like tyrosine kinase 4
chr5_+_129787390 1.536 ENSMUST00000031402.8
 Cct6a
chaperonin containing Tcp1, subunit 6a (zeta)
chr15_-_31601786 1.465 ENSMUST00000022842.8
 Cct5
chaperonin containing Tcp1, subunit 5 (epsilon)
chr17_+_47593444 1.441 ENSMUST00000182209.1
 Ccnd3
cyclin D3
chr12_-_110696332 1.416 ENSMUST00000094361.4
 Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr1_+_91250482 1.390 ENSMUST00000171112.1
 Ube2f
ubiquitin-conjugating enzyme E2F (putative)
chr14_+_34375504 1.283 ENSMUST00000111908.1
 Mmrn2
multimerin 2
chr1_-_119053619 1.240 ENSMUST00000062483.8
 Gli2
GLI-Kruppel family member GLI2
chr8_-_45382198 1.225 ENSMUST00000093526.6
 Fam149a
family with sequence similarity 149, member A
chr15_-_81399594 1.224 ENSMUST00000023039.8
 St13
suppression of tumorigenicity 13
chr18_+_6332587 1.209 ENSMUST00000097682.2
 Rpl27-ps3
ribosomal protein L27, pseudogene 3
chr16_-_87495704 1.190 ENSMUST00000176750.1
ENSMUST00000175977.1
 Cct8

chaperonin containing Tcp1, subunit 8 (theta)

chr6_-_136941887 1.176 ENSMUST00000111891.1
 Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr16_-_87495823 1.139 ENSMUST00000176041.1
ENSMUST00000026704.7
 Cct8

chaperonin containing Tcp1, subunit 8 (theta)

chr5_+_115908644 1.055 ENSMUST00000141101.1
 Cit
citron
chr15_+_75704280 1.046 ENSMUST00000121137.1
ENSMUST00000023244.5
 Rhpn1

rhophilin, Rho GTPase binding protein 1

chr12_+_88083697 1.014 ENSMUST00000177720.1
 Gm16368
predicted pseudogene 16368
chr2_+_25180737 1.006 ENSMUST00000104999.2
 Nrarp
Notch-regulated ankyrin repeat protein
chr10_+_127642975 0.998 ENSMUST00000092074.5
ENSMUST00000120279.1
 Stat6

signal transducer and activator of transcription 6

chr3_-_106547564 0.996 ENSMUST00000121231.1
ENSMUST00000141525.1
 Cept1

choline/ethanolaminephosphotransferase 1

chr6_-_72439549 0.990 ENSMUST00000059472.8
 Mat2a
methionine adenosyltransferase II, alpha
chr6_+_29853746 0.985 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
 Ahcyl2



S-adenosylhomocysteine hydrolase-like 2



chr10_+_80826656 0.967 ENSMUST00000060987.8
ENSMUST00000177850.1
ENSMUST00000180036.1
ENSMUST00000179172.1
 Oaz1



ornithine decarboxylase antizyme 1



chr17_-_50094277 0.944 ENSMUST00000113195.1
 Rftn1
raftlin lipid raft linker 1
chr11_+_82911253 0.931 ENSMUST00000164945.1
ENSMUST00000018989.7
 Unc45b

unc-45 homolog B (C. elegans)

chr2_+_163694015 0.924 ENSMUST00000109400.2
 Pkig
protein kinase inhibitor, gamma
chr11_+_100619217 0.908 ENSMUST00000107376.1
 Nkiras2
NFKB inhibitor interacting Ras-like protein 2
chr12_-_110695860 0.888 ENSMUST00000149189.1
 Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr2_+_157560078 0.876 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
 Nnat







neuronatin







chr13_+_44729535 0.863 ENSMUST00000174068.1
 Jarid2
jumonji, AT rich interactive domain 2
chr4_-_133545906 0.826 ENSMUST00000030665.6
 Nudc
nuclear distribution gene C homolog (Aspergillus)
chr11_+_6560183 0.826 ENSMUST00000109722.2
 Ccm2
cerebral cavernous malformation 2
chr2_+_72297895 0.826 ENSMUST00000144111.1
 Zak
sterile alpha motif and leucine zipper containing kinase AZK
chr17_+_35470083 0.826 ENSMUST00000174525.1
ENSMUST00000068291.6
 H2-Q10

histocompatibility 2, Q region locus 10

chr10_+_59323296 0.808 ENSMUST00000009789.8
ENSMUST00000092512.4
ENSMUST00000105466.2
 P4ha1


procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide


chr4_+_40722912 0.777 ENSMUST00000164233.1
ENSMUST00000137246.1
ENSMUST00000125442.1
 Dnaja1


DnaJ (Hsp40) homolog, subfamily A, member 1


chr12_-_110696289 0.770 ENSMUST00000021698.6
 Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr10_-_61383523 0.764 ENSMUST00000020289.8
 Pald1
phosphatase domain containing, paladin 1
chr19_+_6363896 0.762 ENSMUST00000113487.1
 Sf1
splicing factor 1
chr1_-_55088024 0.762 ENSMUST00000027123.8
 Hspd1
heat shock protein 1 (chaperonin)
chr1_-_55088156 0.760 ENSMUST00000127861.1
ENSMUST00000144077.1
 Hspd1

heat shock protein 1 (chaperonin)

chr12_-_110696248 0.751 ENSMUST00000124156.1
 Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr1_+_55088132 0.748 ENSMUST00000075242.6
 Hspe1
heat shock protein 1 (chaperonin 10)
chr15_+_31602106 0.712 ENSMUST00000042702.6
 Fam173b
family with sequence similarity 173, member B
chr5_+_129020069 0.678 ENSMUST00000031383.7
ENSMUST00000111343.1
 Ran

RAN, member RAS oncogene family

chr9_+_22411515 0.675 ENSMUST00000058868.7
 9530077C05Rik
RIKEN cDNA 9530077C05 gene
chr11_+_83662579 0.674 ENSMUST00000019074.3
 Ccl4
chemokine (C-C motif) ligand 4
chr2_-_92460449 0.673 ENSMUST00000125276.1
 Slc35c1
solute carrier family 35, member C1
chr5_+_149184648 0.654 ENSMUST00000122160.1
ENSMUST00000100410.3
ENSMUST00000119685.1
 Uspl1


ubiquitin specific peptidase like 1


chr4_+_40722461 0.630 ENSMUST00000030118.3
 Dnaja1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr5_+_149184678 0.627 ENSMUST00000139474.1
ENSMUST00000117878.1
 Uspl1

ubiquitin specific peptidase like 1

chr5_+_135887905 0.624 ENSMUST00000005077.6
 Hspb1
heat shock protein 1
chr5_+_149184555 0.618 ENSMUST00000050472.9
 Uspl1
ubiquitin specific peptidase like 1
chr16_-_22265950 0.611 ENSMUST00000161286.1
 Tra2b
transformer 2 beta homolog (Drosophila)
chr15_-_81400043 0.573 ENSMUST00000172107.1
ENSMUST00000169204.1
ENSMUST00000163382.1
 St13


suppression of tumorigenicity 13


chr7_+_49759100 0.540 ENSMUST00000085272.5
 Htatip2
HIV-1 tat interactive protein 2, homolog (human)
chr6_-_51469836 0.530 ENSMUST00000090002.7
 Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chrX_-_140956675 0.529 ENSMUST00000033805.8
ENSMUST00000112978.1
 Psmd10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chr17_+_31564749 0.521 ENSMUST00000175806.1
ENSMUST00000097352.3
 Pknox1

Pbx/knotted 1 homeobox

chr7_-_19310035 0.516 ENSMUST00000003640.2
 Fosb
FBJ osteosarcoma oncogene B
chr9_+_18292267 0.453 ENSMUST00000001825.7
 Chordc1
cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
chr17_+_47593516 0.451 ENSMUST00000182874.1
 Ccnd3
cyclin D3
chr4_+_152178126 0.435 ENSMUST00000075363.3
 Acot7
acyl-CoA thioesterase 7
chr5_+_135887988 0.410 ENSMUST00000111155.1
 Hspb1
heat shock protein 1
chr6_-_51469869 0.406 ENSMUST00000114459.1
ENSMUST00000069949.6
 Hnrnpa2b1

heterogeneous nuclear ribonucleoprotein A2/B1

chr7_+_35586232 0.399 ENSMUST00000040844.9
 Ankrd27
ankyrin repeat domain 27 (VPS9 domain)
chr19_+_6363719 0.394 ENSMUST00000113489.1
ENSMUST00000113488.1
 Sf1

splicing factor 1

chr3_+_79591356 0.383 ENSMUST00000029382.7
 Ppid
peptidylprolyl isomerase D (cyclophilin D)
chr17_+_70929006 0.328 ENSMUST00000092011.6
 Gm16519
predicted gene, 16519
chr7_-_110862944 0.303 ENSMUST00000033050.3
 Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr11_-_5099036 0.298 ENSMUST00000102930.3
 Ewsr1
Ewing sarcoma breakpoint region 1
chr7_-_119895446 0.295 ENSMUST00000098080.2
 Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr4_-_136892867 0.275 ENSMUST00000046332.5
 C1qc
complement component 1, q subcomponent, C chain
chr7_+_111028951 0.274 ENSMUST00000005749.5
 Ctr9
Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr11_-_5099053 0.268 ENSMUST00000093365.5
ENSMUST00000073308.4
 Ewsr1

Ewing sarcoma breakpoint region 1

chr7_+_119895836 0.268 ENSMUST00000106518.1
ENSMUST00000054440.3
 Lyrm1

LYR motif containing 1

chr12_-_54695813 0.261 ENSMUST00000110713.3
 Eapp
E2F-associated phosphoprotein
chr12_-_54695829 0.235 ENSMUST00000162106.1
ENSMUST00000160085.1
ENSMUST00000161592.1
ENSMUST00000163433.1
 Eapp



E2F-associated phosphoprotein



chr7_+_92561141 0.234 ENSMUST00000032842.6
ENSMUST00000085017.4
 Ccdc90b

coiled-coil domain containing 90B

chr11_-_5099223 0.209 ENSMUST00000079949.6
 Ewsr1
Ewing sarcoma breakpoint region 1
chr11_-_5099084 0.191 ENSMUST00000063232.6
 Ewsr1
Ewing sarcoma breakpoint region 1
chr11_-_5542177 0.172 ENSMUST00000020776.4
 Ccdc117
coiled-coil domain containing 117
chr15_-_100403243 0.170 ENSMUST00000124324.1
 Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr5_+_66676098 0.122 ENSMUST00000031131.9
 Uchl1
ubiquitin carboxy-terminal hydrolase L1
chrX_-_150657366 0.119 ENSMUST00000148604.1
 Tro
trophinin
chr8_-_48555846 0.095 ENSMUST00000110345.1
ENSMUST00000110343.1
 Tenm3

teneurin transmembrane protein 3

chr19_+_6363671 0.085 ENSMUST00000131252.1
 Sf1
splicing factor 1
chr15_+_87625214 0.079 ENSMUST00000068088.6
 Fam19a5
family with sequence similarity 19, member A5
chr8_+_36489191 0.048 ENSMUST00000171777.1
 6430573F11Rik
RIKEN cDNA 6430573F11 gene
chr12_+_105784694 0.026 ENSMUST00000109901.2
ENSMUST00000168186.1
ENSMUST00000163473.1
ENSMUST00000170540.1
ENSMUST00000166735.1
ENSMUST00000170002.1
 Papola





poly (A) polymerase alpha





chr1_+_57774842 0.021 ENSMUST00000167085.1
 Spats2l
spermatogenesis associated, serine-rich 2-like
chr12_-_54695885 0.009 ENSMUST00000067272.8
 Eapp
E2F-associated phosphoprotein
chr8_-_109693235 0.003 ENSMUST00000034164.4
 Ist1
increased sodium tolerance 1 homolog (yeast)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.5 6.2 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
1.3 4.0 GO:1903054 lysosomal membrane organization(GO:0097212) negative regulation of extracellular matrix organization(GO:1903054) positive regulation of protein folding(GO:1903334)
0.8 9.2 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.8 2.5 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.7 2.1 GO:0097278 complement-dependent cytotoxicity(GO:0097278)
0.6 3.8 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.5 1.5 GO:0002842 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842)
0.5 1.9 GO:0030576 Cajal body organization(GO:0030576)
0.5 2.8 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.4 2.0 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.3 1.0 GO:0002295 T-helper cell lineage commitment(GO:0002295) interleukin-4-mediated signaling pathway(GO:0035771)
0.3 1.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.3 1.2 GO:0060032 notochord regression(GO:0060032)
0.3 1.8 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.2 1.0 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 1.2 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.2 1.8 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.2 0.7 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.2 4.0 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.2 0.9 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.2 0.5 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.2 0.5 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.2 1.4 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.2 1.0 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.1 1.6 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.1 0.7 GO:1902570 protein localization to nucleolus(GO:1902570)
0.1 0.7 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 1.0 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.9 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.4 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 1.9 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.8 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 1.3 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 1.0 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.3 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 0.5 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 1.2 GO:0030238 male sex determination(GO:0030238)
0.1 0.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.9 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.8 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.1 0.7 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 1.4 GO:0045116 protein neddylation(GO:0045116)
0.1 1.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.3 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.4 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 1.0 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.3 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.6 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.5 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.2 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.8 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.9 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.5 GO:0071277 cellular response to calcium ion(GO:0071277)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.0 GO:0043202 lysosomal lumen(GO:0043202)
0.8 5.9 GO:0097524 sperm plasma membrane(GO:0097524)
0.8 9.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.5 1.0 GO:0097512 cardiac myofibril(GO:0097512)
0.3 1.0 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.3 1.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 0.7 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.2 0.8 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 1.2 GO:0097542 ciliary tip(GO:0097542)
0.1 0.9 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 4.0 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.4 GO:0097422 tubular endosome(GO:0097422)
0.1 1.9 GO:0015030 Cajal body(GO:0015030)
0.0 2.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 2.5 GO:0030315 T-tubule(GO:0030315)
0.0 4.3 GO:0030426 growth cone(GO:0030426)
0.0 1.8 GO:0044452 nucleolar part(GO:0044452)
0.0 1.1 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.6 GO:0005637 nuclear inner membrane(GO:0005637)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0031686 A1 adenosine receptor binding(GO:0031686)
1.0 5.9 GO:0002135 CTP binding(GO:0002135)
0.9 2.6 GO:0008502 melatonin receptor activity(GO:0008502)
0.8 4.0 GO:0032767 copper-dependent protein binding(GO:0032767)
0.6 1.9 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.6 1.8 GO:0032564 dATP binding(GO:0032564)
0.4 1.5 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.4 1.8 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.3 1.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.3 1.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.3 2.5 GO:0031432 titin binding(GO:0031432)
0.2 1.0 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 1.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 2.0 GO:0001972 retinoic acid binding(GO:0001972)
0.2 6.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 1.4 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.2 3.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 1.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.2 1.5 GO:0043559 insulin binding(GO:0043559)
0.2 0.9 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 1.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 0.8 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 1.0 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.7 GO:0070883 importin-alpha family protein binding(GO:0061676) pre-miRNA binding(GO:0070883)
0.1 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.7 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 3.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.9 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 2.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.8 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 1.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.0 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 1.9 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 1.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.9 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.5 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.0 7.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.1 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.0 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.8 GO:0051082 unfolded protein binding(GO:0051082)