Motif ID: Ikzf2

Z-value: 0.794


Transcription factors associated with Ikzf2:

Gene SymbolEntrez IDGene Name
Ikzf2 ENSMUSG00000025997.7 Ikzf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ikzf2mm10_v2_chr1_-_69685937_69685966-0.048.1e-01Click!


Activity profile for motif Ikzf2.

activity profile for motif Ikzf2


Sorted Z-values histogram for motif Ikzf2

Sorted Z-values for motif Ikzf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Ikzf2

PNG image of the network

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Top targets:


Showing 1 to 20 of 106 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_3270767 9.327 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr6_-_23248264 7.892 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr1_+_45311538 5.178 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chrX_+_103422010 4.179 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr6_+_4003926 3.453 ENSMUST00000031670.8
 Gng11
guanine nucleotide binding protein (G protein), gamma 11
chr19_+_55894508 3.365 ENSMUST00000142291.1
 Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr4_+_105157339 2.838 ENSMUST00000064139.7
 Ppap2b
phosphatidic acid phosphatase type 2B
chr11_-_110251736 2.775 ENSMUST00000044003.7
 Abca6
ATP-binding cassette, sub-family A (ABC1), member 6
chr14_+_54936456 2.703 ENSMUST00000037814.6
 Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr1_-_162866502 2.643 ENSMUST00000046049.7
 Fmo1
flavin containing monooxygenase 1
chr13_+_89540636 2.597 ENSMUST00000022108.7
 Hapln1
hyaluronan and proteoglycan link protein 1
chr1_-_45503282 2.459 ENSMUST00000086430.4
 Col5a2
collagen, type V, alpha 2
chr12_+_75308308 2.433 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
 Rhoj


ras homolog gene family, member J


chr11_-_55419898 2.179 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr5_+_30913398 2.169 ENSMUST00000031055.5
 Emilin1
elastin microfibril interfacer 1
chr5_+_92897981 2.112 ENSMUST00000113051.2
 Shroom3
shroom family member 3
chr4_+_57637816 1.944 ENSMUST00000150412.1
 Gm20459
predicted gene 20459
chr7_-_134232005 1.908 ENSMUST00000134504.1
 Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr7_-_134232125 1.891 ENSMUST00000127524.1
 Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr3_-_108017877 1.869 ENSMUST00000004140.4
 Gstm1
glutathione S-transferase, mu 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 9.3 GO:0001887 selenium compound metabolic process(GO:0001887)
1.3 7.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.0 5.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.4 3.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.3 2.9 GO:0042447 hormone catabolic process(GO:0042447)
0.0 2.8 GO:0006869 lipid transport(GO:0006869)
0.1 2.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.3 2.6 GO:0009404 toxin metabolic process(GO:0009404)
0.0 2.6 GO:0098780 mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)
0.8 2.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 2.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 2.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 2.1 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 1.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.3 1.8 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.2 1.8 GO:0061032 visceral serous pericardium development(GO:0061032)
0.6 1.7 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.1 1.7 GO:0031017 exocrine pancreas development(GO:0031017)
0.1 1.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.6 GO:0021884 forebrain neuron development(GO:0021884)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 5.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 4.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.4 3.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 2.9 GO:0005811 lipid particle(GO:0005811)
0.1 2.7 GO:0002102 podosome(GO:0002102)
0.0 2.6 GO:0005581 collagen trimer(GO:0005581)
0.0 2.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.8 2.5 GO:0005588 collagen type V trimer(GO:0005588)
0.5 2.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 2.1 GO:0036064 ciliary basal body(GO:0036064)
0.3 1.6 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 1.4 GO:0097440 apical dendrite(GO:0097440)
0.3 1.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 1.3 GO:0032590 dendrite membrane(GO:0032590)
0.0 1.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 1.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 1.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 12.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 10.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.6 9.3 GO:0008430 selenium binding(GO:0008430)
0.0 4.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.5 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 3.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.4 2.9 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 2.8 GO:0051015 actin filament binding(GO:0051015)
0.5 2.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 2.4 GO:0003924 GTPase activity(GO:0003924)
0.2 2.3 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 2.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 1.9 GO:0016151 nickel cation binding(GO:0016151)
0.4 1.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 1.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.6 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 1.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)