Motif ID: Irf2_Irf1_Irf8_Irf9_Irf7
Z-value: 3.473





Transcription factors associated with Irf2_Irf1_Irf8_Irf9_Irf7:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Irf1 | ENSMUSG00000018899.10 | Irf1 |
Irf2 | ENSMUSG00000031627.7 | Irf2 |
Irf7 | ENSMUSG00000025498.8 | Irf7 |
Irf8 | ENSMUSG00000041515.3 | Irf8 |
Irf9 | ENSMUSG00000002325.8 | Irf9 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Irf1 | mm10_v2_chr11_+_53770458_53770509 | 0.30 | 8.6e-02 | Click! |
Irf8 | mm10_v2_chr8_+_120736352_120736385 | 0.27 | 1.2e-01 | Click! |
Irf9 | mm10_v2_chr14_+_55604550_55604579 | -0.20 | 2.6e-01 | Click! |
Irf2 | mm10_v2_chr8_+_46739745_46739791 | -0.13 | 4.6e-01 | Click! |
Irf7 | mm10_v2_chr7_-_141266415_141266481 | -0.12 | 5.1e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 321 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.2 | 15.8 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
0.6 | 11.8 | GO:0042832 | defense response to protozoan(GO:0042832) |
0.9 | 10.3 | GO:0044458 | motile cilium assembly(GO:0044458) |
1.8 | 9.1 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
1.1 | 8.5 | GO:0048625 | myoblast fate commitment(GO:0048625) |
1.0 | 7.7 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
0.2 | 6.8 | GO:0071346 | cellular response to interferon-gamma(GO:0071346) |
0.1 | 5.9 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
0.7 | 5.8 | GO:1900225 | NLRP3 inflammasome complex assembly(GO:0044546) regulation of NLRP3 inflammasome complex assembly(GO:1900225) |
1.4 | 5.7 | GO:1902990 | mitotic telomere maintenance via semi-conservative replication(GO:1902990) |
0.4 | 5.7 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
1.9 | 5.6 | GO:0006059 | hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401) |
0.3 | 5.6 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
0.7 | 5.5 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
0.2 | 5.5 | GO:0097150 | neuronal stem cell population maintenance(GO:0097150) |
0.1 | 5.5 | GO:0061077 | chaperone-mediated protein folding(GO:0061077) |
0.3 | 5.2 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
0.7 | 4.7 | GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590) |
0.8 | 4.6 | GO:0032488 | Cdc42 protein signal transduction(GO:0032488) |
0.3 | 4.6 | GO:0097066 | response to thyroid hormone(GO:0097066) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 148 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 164.0 | GO:0005575 | cellular_component(GO:0005575) |
2.0 | 25.7 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.9 | 10.9 | GO:0020003 | symbiont-containing vacuole(GO:0020003) |
0.1 | 10.9 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.0 | 10.6 | GO:0005667 | transcription factor complex(GO:0005667) |
0.1 | 10.0 | GO:0036126 | sperm flagellum(GO:0036126) |
1.1 | 9.6 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.1 | 9.6 | GO:0005604 | basement membrane(GO:0005604) |
0.9 | 8.5 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
0.7 | 5.9 | GO:0030478 | actin cap(GO:0030478) |
1.9 | 5.7 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
1.4 | 5.6 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
0.9 | 5.5 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
0.0 | 5.3 | GO:0030496 | midbody(GO:0030496) |
0.1 | 4.2 | GO:0031519 | PcG protein complex(GO:0031519) |
0.3 | 4.1 | GO:0043196 | varicosity(GO:0043196) |
0.2 | 4.1 | GO:0030914 | STAGA complex(GO:0030914) |
0.4 | 4.0 | GO:0000778 | condensed nuclear chromosome kinetochore(GO:0000778) |
0.2 | 3.8 | GO:0005614 | interstitial matrix(GO:0005614) |
0.1 | 3.8 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 221 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 15.5 | GO:0043774 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738) |
0.9 | 12.2 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
0.1 | 11.0 | GO:0003924 | GTPase activity(GO:0003924) |
0.4 | 10.5 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
1.9 | 9.5 | GO:0032027 | myosin light chain binding(GO:0032027) |
0.4 | 8.5 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.1 | 7.9 | GO:0001948 | glycoprotein binding(GO:0001948) |
0.2 | 6.6 | GO:0004812 | aminoacyl-tRNA ligase activity(GO:0004812) |
0.2 | 6.5 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
0.0 | 6.2 | GO:0004386 | helicase activity(GO:0004386) |
2.0 | 6.1 | GO:0030337 | DNA polymerase processivity factor activity(GO:0030337) |
0.0 | 6.0 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.0 | 6.0 | GO:0003779 | actin binding(GO:0003779) |
0.2 | 5.8 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.5 | 5.5 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.1 | 5.3 | GO:0098811 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
1.2 | 5.0 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
0.3 | 4.8 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.0 | 4.8 | GO:0005525 | GTP binding(GO:0005525) |
0.4 | 4.7 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |