Z-value: 0.659
Transcription factors associated with Irf3:
Activity-expression correlation:
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Showing 1 to 20 of 69 entries
Gene overrepresentation in biological_process category:
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Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihood Term Description
0.5
7.7
GO:0044406 adhesion of symbiont to host(GO:0044406)
0.9
3.5
GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.5
2.4
GO:1900122 positive regulation of receptor binding(GO:1900122)
0.3
2.1
GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.4
1.7
GO:0009597 detection of virus(GO:0009597)
0.2
1.3
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2
1.0
GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1
0.8
GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0
0.8
GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.2
0.7
GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.1
0.7
GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.2
0.6
GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1
0.5
GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1
0.5
GO:0034421 post-translational protein acetylation(GO:0034421)
0.0
0.5
GO:0031648 protein destabilization(GO:0031648)
0.1
0.4
GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0
0.4
GO:0016082 synaptic vesicle priming(GO:0016082)
0.1
0.3
GO:0042228 interleukin-8 biosynthetic process(GO:0042228)
0.0
0.3
GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0
0.3
GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
Gene overrepresentation in cellular_component category:
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Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihood Term Description
0.7
7.7
GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.8
2.4
GO:0042025 viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.2
2.4
GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0
1.9
GO:0005770 late endosome(GO:0005770)
0.0
1.7
GO:0032587 ruffle membrane(GO:0032587)
0.0
1.3
GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0
1.2
GO:0031519 PcG protein complex(GO:0031519)
0.0
1.1
GO:0036126 sperm flagellum(GO:0036126)
0.1
1.0
GO:0042825 TAP complex(GO:0042825)
0.3
0.8
GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.0
0.8
GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0
0.7
GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1
0.5
GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0
0.5
GO:0031901 early endosome membrane(GO:0031901)
0.0
0.4
GO:0030914 STAGA complex(GO:0030914)
0.1
0.3
GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2
0.2
GO:0020003 symbiont-containing vacuole(GO:0020003)
0.0
0.2
GO:0005915 zonula adherens(GO:0005915)
0.0
0.2
GO:0005677 chromatin silencing complex(GO:0005677)
0.0
0.2
GO:0031083 BLOC-1 complex(GO:0031083)
Gene overrepresentation in molecular_function category:
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Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihood Term Description
0.0
5.7
GO:0003924 GTPase activity(GO:0003924)
0.2
3.6
GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0
2.5
GO:0003725 double-stranded RNA binding(GO:0003725)
0.5
2.4
GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0
1.9
GO:0005525 GTP binding(GO:0005525)
0.0
1.8
GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.2
1.3
GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1
1.1
GO:0039706 co-receptor binding(GO:0039706)
0.1
1.1
GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2
1.0
GO:0023029 peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980)
0.0
1.0
GO:0051082 unfolded protein binding(GO:0051082)
0.3
0.8
GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.2
0.8
GO:0050436 microfibril binding(GO:0050436)
0.1
0.5
GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0
0.5
GO:0050699 WW domain binding(GO:0050699)
0.0
0.3
GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0
0.3
GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0
0.2
GO:0070097 delta-catenin binding(GO:0070097)
