Motif ID: Jun

Z-value: 0.538


Transcription factors associated with Jun:

Gene SymbolEntrez IDGene Name
Jun ENSMUSG00000052684.3 Jun

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Junmm10_v2_chr4_-_95052188_950522220.431.2e-02Click!


Activity profile for motif Jun.

activity profile for motif Jun


Sorted Z-values histogram for motif Jun

Sorted Z-values for motif Jun



Network of associatons between targets according to the STRING database.



First level regulatory network of Jun

PNG image of the network

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Top targets:


Showing 1 to 20 of 195 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_65968483 5.477 ENSMUST00000022616.6
 Clu
clusterin
chr2_+_25395866 4.482 ENSMUST00000028328.2
 Entpd2
ectonucleoside triphosphate diphosphohydrolase 2
chr7_+_139834148 2.422 ENSMUST00000026548.7
 Gpr123
G protein-coupled receptor 123
chr10_+_128933782 2.368 ENSMUST00000099112.2
 Itga7
integrin alpha 7
chr5_-_62766153 2.278 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr7_+_110772604 2.201 ENSMUST00000005829.6
 Ampd3
adenosine monophosphate deaminase 3
chr19_-_36736653 2.178 ENSMUST00000087321.2
 Ppp1r3c
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr7_-_105482197 2.109 ENSMUST00000047040.2
 Prkcdbp
protein kinase C, delta binding protein
chr10_+_94550852 1.979 ENSMUST00000148910.1
ENSMUST00000117460.1
 Tmcc3

transmembrane and coiled coil domains 3

chr2_-_17731035 1.867 ENSMUST00000028080.5
 Nebl
nebulette
chr3_+_121723515 1.693 ENSMUST00000029771.8
 F3
coagulation factor III
chr14_+_34310727 1.671 ENSMUST00000022322.9
 Glud1
glutamate dehydrogenase 1
chr9_-_86695897 1.661 ENSMUST00000034989.8
 Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr2_+_71117923 1.614 ENSMUST00000028403.2
 Cybrd1
cytochrome b reductase 1
chr12_+_75308308 1.574 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
 Rhoj


ras homolog gene family, member J


chr6_+_17281185 1.519 ENSMUST00000000058.6
 Cav2
caveolin 2
chr6_+_17281304 1.458 ENSMUST00000115459.1
ENSMUST00000115462.1
 Cav2

caveolin 2

chr15_-_97767644 1.396 ENSMUST00000128775.2
ENSMUST00000134885.2
 Rapgef3

Rap guanine nucleotide exchange factor (GEF) 3

chr15_-_97767798 1.391 ENSMUST00000129223.2
ENSMUST00000126854.2
ENSMUST00000135080.1
 Rapgef3


Rap guanine nucleotide exchange factor (GEF) 3


chr3_-_116129615 1.377 ENSMUST00000029574.8
 Vcam1
vascular cell adhesion molecule 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 75 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 5.5 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.6 4.5 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.6 3.0 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.7 2.8 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.3 2.8 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 2.3 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.3 2.2 GO:0032264 IMP salvage(GO:0032264)
0.0 2.2 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.7 2.1 GO:0043465 regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003)
0.4 1.7 GO:0006538 glutamate catabolic process(GO:0006538)
0.3 1.7 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 1.7 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.1 1.6 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 1.6 GO:0010039 response to iron ion(GO:0010039)
0.1 1.4 GO:0061032 visceral serous pericardium development(GO:0061032)
0.4 1.3 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.3 1.2 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.2 1.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 1.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 1.2 GO:0033198 response to ATP(GO:0033198)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 5.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.0 4.2 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 3.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.2 3.0 GO:0002080 acrosomal membrane(GO:0002080)
0.7 2.8 GO:1990795 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.8 2.4 GO:0005927 muscle tendon junction(GO:0005927)
0.2 2.2 GO:0042587 glycogen granule(GO:0042587)
0.0 2.2 GO:0005901 caveola(GO:0005901)
0.1 2.0 GO:0005605 basal lamina(GO:0005605)
0.0 1.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.7 GO:0031526 brush border membrane(GO:0031526)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.3 1.2 GO:0097227 sperm annulus(GO:0097227)
0.2 1.2 GO:0097513 myosin II filament(GO:0097513)
0.2 1.2 GO:0005638 lamin filament(GO:0005638)
0.1 1.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 1.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.1 GO:0002102 podosome(GO:0002102)
0.0 1.1 GO:0030315 T-tubule(GO:0030315)
0.1 1.0 GO:0000138 Golgi trans cisterna(GO:0000138)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.5 GO:0051787 misfolded protein binding(GO:0051787)
0.6 4.5 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 4.2 GO:0032561 guanyl ribonucleotide binding(GO:0032561)
0.1 3.0 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.3 2.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 2.4 GO:0043236 laminin binding(GO:0043236)
0.1 2.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3 2.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 2.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.9 GO:0005080 protein kinase C binding(GO:0005080)
0.6 1.7 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.3 1.7 GO:0070728 leucine binding(GO:0070728)
0.0 1.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.3 1.6 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.3 1.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 1.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 1.2 GO:0038132 neuregulin binding(GO:0038132)
0.2 1.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 1.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)