Motif ID: Klf15

Z-value: 1.308


Transcription factors associated with Klf15:

Gene SymbolEntrez IDGene Name
Klf15 ENSMUSG00000030087.5 Klf15

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf15mm10_v2_chr6_+_90465287_904653040.484.4e-03Click!


Activity profile for motif Klf15.

activity profile for motif Klf15


Sorted Z-values histogram for motif Klf15

Sorted Z-values for motif Klf15



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf15

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_56971762 6.851 ENSMUST00000114415.3
 Satb2
special AT-rich sequence binding protein 2
chr18_-_89769479 6.631 ENSMUST00000097495.3
 Dok6
docking protein 6
chr7_+_46396439 6.151 ENSMUST00000025202.6
 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr4_+_97777780 5.870 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
 Nfia


nuclear factor I/A


chr17_+_46297917 5.266 ENSMUST00000166617.1
ENSMUST00000170271.1
 Dlk2

delta-like 2 homolog (Drosophila)

chr11_+_69765970 5.231 ENSMUST00000108642.1
ENSMUST00000156932.1
 Zbtb4

zinc finger and BTB domain containing 4

chr7_+_126776939 5.222 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
 Ypel3






yippee-like 3 (Drosophila)






chr11_+_24076529 5.028 ENSMUST00000148087.1
 Gm12063
predicted gene 12063
chr11_+_69765899 4.989 ENSMUST00000108640.1
ENSMUST00000108639.1
 Zbtb4

zinc finger and BTB domain containing 4

chr2_-_5714490 4.582 ENSMUST00000044009.7
 Camk1d
calcium/calmodulin-dependent protein kinase ID
chr1_-_56972437 4.251 ENSMUST00000042857.7
 Satb2
special AT-rich sequence binding protein 2
chr19_+_5740885 4.163 ENSMUST00000081496.5
 Ltbp3
latent transforming growth factor beta binding protein 3
chr9_+_45430293 3.963 ENSMUST00000034592.8
 Dscaml1
Down syndrome cell adhesion molecule like 1
chr4_+_129985098 3.911 ENSMUST00000106017.1
ENSMUST00000121049.1
 Bai2

brain-specific angiogenesis inhibitor 2

chr11_+_98348404 3.862 ENSMUST00000078694.6
 Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr11_+_77930800 3.860 ENSMUST00000093995.3
ENSMUST00000000646.7
 Sez6

seizure related gene 6

chr11_-_97573929 3.767 ENSMUST00000126287.1
ENSMUST00000107590.1
 Srcin1

SRC kinase signaling inhibitor 1

chr2_-_20968881 3.670 ENSMUST00000114594.1
 Arhgap21
Rho GTPase activating protein 21
chr18_-_31949571 3.620 ENSMUST00000064016.5
 Gpr17
G protein-coupled receptor 17
chr8_+_93810832 3.587 ENSMUST00000034198.8
ENSMUST00000125716.1
 Gnao1

guanine nucleotide binding protein, alpha O


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 135 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 11.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 7.8 GO:0060074 synapse maturation(GO:0060074)
1.2 7.4 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.3 7.3 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 6.2 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.2 6.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 5.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
1.0 5.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
1.6 4.8 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.7 4.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.4 4.3 GO:0006691 leukotriene metabolic process(GO:0006691)
1.4 4.2 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
1.3 4.0 GO:0071544 diphosphoinositol polyphosphate metabolic process(GO:0071543) diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.5 4.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
1.3 3.9 GO:0007621 negative regulation of female receptivity(GO:0007621)
1.0 3.9 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.7 3.7 GO:0051684 maintenance of Golgi location(GO:0051684)
0.4 3.6 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.5 3.5 GO:0016584 nucleosome positioning(GO:0016584)
0.8 3.2 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 69 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.8 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 7.3 GO:0030175 filopodium(GO:0030175)
0.1 7.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 6.5 GO:0042734 presynaptic membrane(GO:0042734)
0.2 6.2 GO:0030673 axolemma(GO:0030673)
0.2 6.2 GO:0097440 apical dendrite(GO:0097440)
0.0 5.9 GO:0043025 neuronal cell body(GO:0043025)
0.0 5.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 5.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 3.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 3.5 GO:0031256 leading edge membrane(GO:0031256)
0.0 3.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 3.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.2 2.9 GO:0097228 sperm principal piece(GO:0097228)
0.7 2.8 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.5 2.7 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 2.7 GO:0000124 SAGA complex(GO:0000124)
0.1 2.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 2.7 GO:0008021 synaptic vesicle(GO:0008021)
0.0 2.4 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 95 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 10.4 GO:0070412 R-SMAD binding(GO:0070412)
0.4 10.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.3 9.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 8.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 6.6 GO:0005158 insulin receptor binding(GO:0005158)
0.2 6.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 5.3 GO:0008083 growth factor activity(GO:0008083)
0.0 5.3 GO:0005096 GTPase activator activity(GO:0005096)
0.1 4.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.7 4.0 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
1.3 3.9 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.3 3.9 GO:0070636 single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.6 3.6 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.8 3.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.4 3.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 3.1 GO:0019003 GDP binding(GO:0019003)
0.0 3.0 GO:0005518 collagen binding(GO:0005518)
0.2 2.9 GO:0042805 actinin binding(GO:0042805)
0.1 2.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.5 2.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)