Motif ID: Klf6_Patz1

Z-value: 2.622

Transcription factors associated with Klf6_Patz1:

Gene SymbolEntrez IDGene Name
Klf6 ENSMUSG00000000078.6 Klf6
Patz1 ENSMUSG00000020453.11 Patz1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf6mm10_v2_chr13_+_5861489_5861501-0.654.4e-05Click!
Patz1mm10_v2_chr11_+_3290300_32904570.241.9e-01Click!


Activity profile for motif Klf6_Patz1.

activity profile for motif Klf6_Patz1


Sorted Z-values histogram for motif Klf6_Patz1

Sorted Z-values for motif Klf6_Patz1



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf6_Patz1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_172057573 14.721 ENSMUST00000059794.3
 Nhlh1
nescient helix loop helix 1
chr11_-_102296618 13.613 ENSMUST00000107132.2
ENSMUST00000073234.2
 Atxn7l3

ataxin 7-like 3

chr10_-_127534540 13.334 ENSMUST00000095266.2
 Nxph4
neurexophilin 4
chr7_+_29289300 11.097 ENSMUST00000048187.4
 Ppp1r14a
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr11_+_101468164 10.964 ENSMUST00000001347.6
 Rnd2
Rho family GTPase 2
chr4_+_116877376 10.649 ENSMUST00000044823.3
 Zswim5
zinc finger SWIM-type containing 5
chr7_+_44310213 9.908 ENSMUST00000107938.1
 Shank1
SH3/ankyrin domain gene 1
chr1_+_136131382 9.714 ENSMUST00000075164.4
 Kif21b
kinesin family member 21B
chr17_+_28142267 9.694 ENSMUST00000043503.3
 Scube3
signal peptide, CUB domain, EGF-like 3
chr5_-_138279960 9.185 ENSMUST00000014089.7
ENSMUST00000161827.1
 Gpc2

glypican 2 (cerebroglycan)

chr5_+_37028329 8.678 ENSMUST00000173836.1
 Jakmip1
janus kinase and microtubule interacting protein 1
chr7_-_143460989 8.611 ENSMUST00000167912.1
ENSMUST00000037287.6
 Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr7_+_127746775 8.110 ENSMUST00000033081.7
 Fbxl19
F-box and leucine-rich repeat protein 19
chr10_-_127060163 7.920 ENSMUST00000040307.5
 March9
membrane-associated ring finger (C3HC4) 9
chr2_-_84886692 7.899 ENSMUST00000054514.5
ENSMUST00000151799.1
 Rtn4rl2

reticulon 4 receptor-like 2

chr9_-_106656081 7.814 ENSMUST00000023959.7
 Grm2
glutamate receptor, metabotropic 2
chr13_-_56252163 7.702 ENSMUST00000058475.4
 Neurog1
neurogenin 1
chr7_+_126950837 7.486 ENSMUST00000106332.1
 Sez6l2
seizure related 6 homolog like 2
chr15_-_76521902 7.340 ENSMUST00000164703.1
ENSMUST00000096365.3
 Scrt1

scratch homolog 1, zinc finger protein (Drosophila)

chr11_-_101466222 7.283 ENSMUST00000040430.7
 Vat1
vesicle amine transport protein 1 homolog (T californica)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 769 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.5 32.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
1.1 22.0 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.6 18.7 GO:0016578 histone deubiquitination(GO:0016578)
0.8 16.8 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
1.5 16.0 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
1.1 14.3 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.9 13.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.5 13.3 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.4 12.6 GO:0007520 myoblast fusion(GO:0007520)
0.2 12.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
1.6 12.4 GO:0035608 protein deglutamylation(GO:0035608)
0.4 12.0 GO:2001222 regulation of neuron migration(GO:2001222)
2.0 11.7 GO:0021636 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637)
2.9 11.6 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.6 10.8 GO:0060065 uterus development(GO:0060065)
0.7 10.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
3.3 9.9 GO:0046959 habituation(GO:0046959)
0.7 9.9 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.3 9.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.3 9.8 GO:0048255 mRNA stabilization(GO:0048255)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 280 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 25.4 GO:0070382 exocytic vesicle(GO:0070382)
1.0 21.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.6 19.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 17.5 GO:0016604 nuclear body(GO:0016604)
0.3 17.4 GO:0072686 mitotic spindle(GO:0072686)
0.5 17.0 GO:0030426 growth cone(GO:0030426)
0.3 16.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.7 16.5 GO:0071565 nBAF complex(GO:0071565)
0.2 16.5 GO:0043198 dendritic shaft(GO:0043198)
1.5 15.3 GO:0044327 dendritic spine head(GO:0044327)
0.4 15.3 GO:0044295 axonal growth cone(GO:0044295)
1.2 14.0 GO:0000124 SAGA complex(GO:0000124)
0.2 12.8 GO:0005844 polysome(GO:0005844)
0.3 12.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 12.5 GO:0016459 myosin complex(GO:0016459)
0.3 12.2 GO:1990391 DNA repair complex(GO:1990391)
0.1 12.1 GO:0005802 trans-Golgi network(GO:0005802)
0.7 11.6 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.4 11.1 GO:0031941 filamentous actin(GO:0031941)
0.8 9.9 GO:0008385 IkappaB kinase complex(GO:0008385)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 421 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 57.1 GO:0003723 RNA binding(GO:0003723)
0.1 24.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.5 21.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.4 21.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 20.7 GO:0008270 zinc ion binding(GO:0008270)
0.8 20.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 19.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3 18.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
1.2 17.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 16.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 15.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.2 15.0 GO:0003777 microtubule motor activity(GO:0003777)
0.6 14.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
1.8 14.6 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 14.2 GO:0017137 Rab GTPase binding(GO:0017137)
1.5 13.7 GO:0008046 axon guidance receptor activity(GO:0008046)
1.5 13.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.7 13.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.7 12.9 GO:0050811 GABA receptor binding(GO:0050811)
0.4 12.6 GO:0042162 telomeric DNA binding(GO:0042162)