Motif ID: Klf7

Z-value: 0.677


Transcription factors associated with Klf7:

Gene SymbolEntrez IDGene Name
Klf7 ENSMUSG00000025959.7 Klf7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf7mm10_v2_chr1_-_64121456_641214910.639.4e-05Click!


Activity profile for motif Klf7.

activity profile for motif Klf7


Sorted Z-values histogram for motif Klf7

Sorted Z-values for motif Klf7



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf7

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_156312470 4.635 ENSMUST00000079125.6
 Scand1
SCAN domain-containing 1
chr6_-_88875035 4.030 ENSMUST00000145944.1
 Podxl2
podocalyxin-like 2
chr5_-_137741601 3.087 ENSMUST00000119498.1
ENSMUST00000061789.7
 Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr12_-_4592927 2.966 ENSMUST00000170816.1
 Gm3625
predicted gene 3625
chr3_+_28263205 2.934 ENSMUST00000159236.2
 Tnik
TRAF2 and NCK interacting kinase
chr5_+_137778849 2.736 ENSMUST00000126126.1
ENSMUST00000031739.4
 Ppp1r35

protein phosphatase 1, regulatory subunit 35

chr6_-_88874597 2.663 ENSMUST00000061262.4
ENSMUST00000140455.1
ENSMUST00000145780.1
 Podxl2


podocalyxin-like 2


chr7_-_74013676 2.476 ENSMUST00000026896.4
 St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr4_+_107830958 2.323 ENSMUST00000106731.2
 Lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chrY_+_897782 1.897 ENSMUST00000055032.7
 Kdm5d
lysine (K)-specific demethylase 5D
chr12_+_49382791 1.831 ENSMUST00000179669.1
 Foxg1
forkhead box G1
chr6_+_52714219 1.754 ENSMUST00000138040.1
ENSMUST00000129660.1
 Tax1bp1

Tax1 (human T cell leukemia virus type I) binding protein 1

chr15_-_102722150 1.668 ENSMUST00000023818.3
 Calcoco1
calcium binding and coiled coil domain 1
chr12_+_49383007 1.579 ENSMUST00000021333.3
 Foxg1
forkhead box G1
chr15_-_102722120 1.560 ENSMUST00000171838.1
 Calcoco1
calcium binding and coiled coil domain 1
chr1_-_138847579 1.439 ENSMUST00000093486.3
ENSMUST00000046870.6
 Lhx9

LIM homeobox protein 9

chr7_-_28766469 1.425 ENSMUST00000085851.5
ENSMUST00000032815.4
 Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

chr3_+_106721893 1.300 ENSMUST00000106736.2
ENSMUST00000154973.1
ENSMUST00000131330.1
ENSMUST00000150513.1
 Lrif1



ligand dependent nuclear receptor interacting factor 1



chr6_+_125039760 1.233 ENSMUST00000140131.1
ENSMUST00000032480.7
 Ing4

inhibitor of growth family, member 4

chr1_-_23383149 1.219 ENSMUST00000027343.5
 Ogfrl1
opioid growth factor receptor-like 1
chr3_+_106721672 1.159 ENSMUST00000098750.2
ENSMUST00000130105.1
 Lrif1

ligand dependent nuclear receptor interacting factor 1

chr15_+_30172570 1.148 ENSMUST00000081728.5
 Ctnnd2
catenin (cadherin associated protein), delta 2
chr11_-_61494173 1.072 ENSMUST00000101085.2
ENSMUST00000079080.6
ENSMUST00000108714.1
 Mapk7


mitogen-activated protein kinase 7


chr2_+_32775769 1.056 ENSMUST00000066352.5
 Ptrh1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr9_-_32344237 1.040 ENSMUST00000034533.5
 Kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
chr2_-_73892619 0.988 ENSMUST00000112007.1
ENSMUST00000112016.2
 Atf2

activating transcription factor 2

chr2_-_130424242 0.966 ENSMUST00000089581.4
 Pced1a
PC-esterase domain containing 1A
chr18_+_67133713 0.949 ENSMUST00000076605.7
 Gnal
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr17_+_24488773 0.928 ENSMUST00000024958.7
 Caskin1
CASK interacting protein 1
chr6_+_52713729 0.898 ENSMUST00000080723.4
ENSMUST00000149588.1
 Tax1bp1

Tax1 (human T cell leukemia virus type I) binding protein 1

chr15_-_89196457 0.889 ENSMUST00000078953.7
 Dennd6b
DENN/MADD domain containing 6B
chr2_-_73892588 0.839 ENSMUST00000154456.1
ENSMUST00000090802.4
ENSMUST00000055833.5
 Atf2


activating transcription factor 2


chr7_-_68749170 0.778 ENSMUST00000118110.1
ENSMUST00000048068.7
 Arrdc4

arrestin domain containing 4

chr7_+_28766747 0.762 ENSMUST00000170068.1
ENSMUST00000072965.4
 Sirt2

sirtuin 2

chr4_+_139622842 0.760 ENSMUST00000039818.9
 Aldh4a1
aldehyde dehydrogenase 4 family, member A1
chr5_+_137761680 0.710 ENSMUST00000110983.2
ENSMUST00000031738.4
 Tsc22d4

TSC22 domain family, member 4

chr4_+_152178126 0.690 ENSMUST00000075363.3
 Acot7
acyl-CoA thioesterase 7
chr2_-_73892530 0.666 ENSMUST00000136958.1
ENSMUST00000112010.2
ENSMUST00000128531.1
ENSMUST00000112017.1
 Atf2



activating transcription factor 2



chr5_-_34187670 0.654 ENSMUST00000042701.6
ENSMUST00000119171.1
 Mxd4

Max dimerization protein 4

chr12_-_11436607 0.639 ENSMUST00000072299.5
 Vsnl1
visinin-like 1
chr5_-_115348953 0.620 ENSMUST00000040154.8
 Cox6a1
cytochrome c oxidase subunit VIa polypeptide 1
chr5_-_124187150 0.618 ENSMUST00000161938.1
 Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr2_-_151973387 0.607 ENSMUST00000109863.1
 Fam110a
family with sequence similarity 110, member A
chr8_+_71367210 0.567 ENSMUST00000019169.7
 Use1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr4_-_87230435 0.540 ENSMUST00000107157.2
 Slc24a2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr2_+_156312589 0.529 ENSMUST00000073942.5
ENSMUST00000109580.1
 Cnbd2

cyclic nucleotide binding domain containing 2

chr11_+_78536355 0.528 ENSMUST00000128788.1
 Ift20
intraflagellar transport 20
chr8_+_3500451 0.525 ENSMUST00000004683.6
ENSMUST00000160338.1
 Mcoln1

mucolipin 1

chr11_-_101302206 0.479 ENSMUST00000140706.1
ENSMUST00000170502.1
ENSMUST00000172233.1
ENSMUST00000130916.1
 Becn1



beclin 1, autophagy related



chr15_-_98953541 0.466 ENSMUST00000097014.5
 Tuba1a
tubulin, alpha 1A
chr8_-_22476809 0.445 ENSMUST00000163774.1
ENSMUST00000033935.8
 Smim19

small integral membrane protein 19

chr11_+_78536393 0.428 ENSMUST00000050366.8
ENSMUST00000108275.1
 Ift20

intraflagellar transport 20

chr7_+_80261202 0.400 ENSMUST00000117989.1
 Ngrn
neugrin, neurite outgrowth associated
chr8_+_3621529 0.383 ENSMUST00000156380.2
 Pet100
PET100 homolog (S. cerevisiae)
chr7_-_141414115 0.380 ENSMUST00000106008.1
 Pddc1
Parkinson disease 7 domain containing 1
chr1_+_171329015 0.360 ENSMUST00000111300.1
 Dedd
death effector domain-containing
chr7_+_45154644 0.345 ENSMUST00000153973.1
 Pih1d1
PIH1 domain containing 1
chr2_-_156180135 0.343 ENSMUST00000126992.1
ENSMUST00000146288.1
ENSMUST00000029149.6
ENSMUST00000109587.2
ENSMUST00000109584.1
 Rbm39




RNA binding motif protein 39




chr7_+_45154297 0.341 ENSMUST00000107813.1
ENSMUST00000125953.1
ENSMUST00000085375.5
ENSMUST00000144597.1
 Pih1d1



PIH1 domain containing 1



chr4_-_132329414 0.333 ENSMUST00000127402.1
ENSMUST00000105962.3
ENSMUST00000030730.7
ENSMUST00000105960.1
 Trnau1ap



tRNA selenocysteine 1 associated protein 1



chr2_+_119047116 0.287 ENSMUST00000152380.1
ENSMUST00000099542.2
 Casc5

cancer susceptibility candidate 5

chr7_+_126976338 0.282 ENSMUST00000032920.3
 Cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr2_-_130424673 0.276 ENSMUST00000110277.1
 Pced1a
PC-esterase domain containing 1A
chr13_+_96542727 0.257 ENSMUST00000077672.4
ENSMUST00000109444.2
 Col4a3bp

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr10_-_86705485 0.241 ENSMUST00000020238.7
 Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr10_+_86705811 0.241 ENSMUST00000061458.7
ENSMUST00000075632.6
 BC030307

cDNA sequence BC030307

chr8_+_71922810 0.230 ENSMUST00000119003.1
 Zfp617
zinc finger protein 617
chr11_+_72301613 0.220 ENSMUST00000151440.1
ENSMUST00000146233.1
ENSMUST00000140842.2
 Xaf1


XIAP associated factor 1


chr1_+_163929765 0.212 ENSMUST00000027876.4
ENSMUST00000170359.1
 Scyl3

SCY1-like 3 (S. cerevisiae)

chr4_+_127126034 0.210 ENSMUST00000094712.4
 Gm12942
predicted gene 12942
chr14_+_79451791 0.203 ENSMUST00000100359.1
 Zbtbd6
kelch repeat and BTB (POZ) domain containing 6
chr1_+_57406328 0.190 ENSMUST00000027114.5
 9430016H08Rik
RIKEN cDNA 9430016H08 gene
chr5_+_45520221 0.177 ENSMUST00000156481.1
ENSMUST00000119579.1
ENSMUST00000118833.1
 Med28


mediator of RNA polymerase II transcription, subunit 28 homolog (yeast)


chr2_+_119047129 0.176 ENSMUST00000153300.1
ENSMUST00000028799.5
 Casc5

cancer susceptibility candidate 5

chr11_+_42419729 0.174 ENSMUST00000007797.4
 Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr1_+_172082796 0.154 ENSMUST00000027833.5
 Copa
coatomer protein complex subunit alpha
chr5_-_3596071 0.119 ENSMUST00000121877.1
 Rbm48
RNA binding motif protein 48
chr5_+_3596066 0.118 ENSMUST00000006061.6
ENSMUST00000121291.1
ENSMUST00000142516.1
 Pex1


peroxisomal biogenesis factor 1


chr1_-_57406443 0.116 ENSMUST00000160837.1
ENSMUST00000161780.1
 Tyw5

tRNA-yW synthesizing protein 5

chr13_-_67451585 0.092 ENSMUST00000057241.8
ENSMUST00000075255.5
 Zfp874a

zinc finger protein 874a

chr1_+_120121161 0.086 ENSMUST00000027637.6
ENSMUST00000112644.2
ENSMUST00000056038.8
 3110009E18Rik


RIKEN cDNA 3110009E18 gene


chr3_+_51224447 0.071 ENSMUST00000023849.8
ENSMUST00000167780.1
 Ccrn4l

CCR4 carbon catabolite repression 4-like (S. cerevisiae)

chr1_-_172082757 0.069 ENSMUST00000003550.4
 Ncstn
nicastrin
chr19_-_8723356 0.059 ENSMUST00000170157.1
 Slc3a2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr7_-_132776855 0.057 ENSMUST00000106168.1
 Fam53b
family with sequence similarity 53, member B
chr1_+_172082509 0.001 ENSMUST00000135192.1
 Copa
coatomer protein complex subunit alpha

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0021852 pyramidal neuron migration(GO:0021852)
0.8 2.5 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.6 2.9 GO:0007256 activation of JNKK activity(GO:0007256)
0.4 6.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.4 1.9 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.4 1.1 GO:0070375 ERK5 cascade(GO:0070375)
0.3 1.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.3 2.3 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.2 1.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2 1.2 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.2 1.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.2 0.7 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.2 0.7 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.1 2.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 1.0 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.8 GO:0006537 glutamate biosynthetic process(GO:0006537) proline biosynthetic process(GO:0006561)
0.1 0.3 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.9 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.3 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.1 0.4 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.3 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 3.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 1.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.6 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 3.1 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 1.9 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.4 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.2 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.8 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 3.0 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.6 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 1.1 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.1 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.5 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.3 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.2 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.7 GO:0006970 response to osmotic stress(GO:0006970)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.8 GO:0033010 paranodal junction(GO:0033010)
0.1 0.7 GO:0097255 R2TP complex(GO:0097255)
0.1 0.5 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 2.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 6.6 GO:0055037 recycling endosome(GO:0055037)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.2 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.2 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.7 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 1.0 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0038025 reelin receptor activity(GO:0038025)
0.4 2.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 0.9 GO:0050827 toxin receptor binding(GO:0050827)
0.3 1.9 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.2 1.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 1.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 2.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 0.8 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.2 0.5 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 3.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.4 GO:0019172 glyoxalase III activity(GO:0019172)
0.1 0.3 GO:0097001 sphingolipid transporter activity(GO:0046624) ceramide binding(GO:0097001)
0.0 2.5 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.7 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 1.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.8 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 1.1 GO:0004707 MAP kinase activity(GO:0004707)
0.0 2.9 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.3 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 6.2 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.7 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.5 GO:0030552 cAMP binding(GO:0030552)