Motif ID: Klf7

Z-value: 0.677


Transcription factors associated with Klf7:

Gene SymbolEntrez IDGene Name
Klf7 ENSMUSG00000025959.7 Klf7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf7mm10_v2_chr1_-_64121456_641214910.639.4e-05Click!


Activity profile for motif Klf7.

activity profile for motif Klf7


Sorted Z-values histogram for motif Klf7

Sorted Z-values for motif Klf7



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf7

PNG image of the network

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Top targets:


Showing 1 to 20 of 86 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_156312470 4.635 ENSMUST00000079125.6
 Scand1
SCAN domain-containing 1
chr6_-_88875035 4.030 ENSMUST00000145944.1
 Podxl2
podocalyxin-like 2
chr5_-_137741601 3.087 ENSMUST00000119498.1
ENSMUST00000061789.7
 Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr12_-_4592927 2.966 ENSMUST00000170816.1
 Gm3625
predicted gene 3625
chr3_+_28263205 2.934 ENSMUST00000159236.2
 Tnik
TRAF2 and NCK interacting kinase
chr5_+_137778849 2.736 ENSMUST00000126126.1
ENSMUST00000031739.4
 Ppp1r35

protein phosphatase 1, regulatory subunit 35

chr6_-_88874597 2.663 ENSMUST00000061262.4
ENSMUST00000140455.1
ENSMUST00000145780.1
 Podxl2


podocalyxin-like 2


chr7_-_74013676 2.476 ENSMUST00000026896.4
 St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr4_+_107830958 2.323 ENSMUST00000106731.2
 Lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chrY_+_897782 1.897 ENSMUST00000055032.7
 Kdm5d
lysine (K)-specific demethylase 5D
chr12_+_49382791 1.831 ENSMUST00000179669.1
 Foxg1
forkhead box G1
chr6_+_52714219 1.754 ENSMUST00000138040.1
ENSMUST00000129660.1
 Tax1bp1

Tax1 (human T cell leukemia virus type I) binding protein 1

chr15_-_102722150 1.668 ENSMUST00000023818.3
 Calcoco1
calcium binding and coiled coil domain 1
chr12_+_49383007 1.579 ENSMUST00000021333.3
 Foxg1
forkhead box G1
chr15_-_102722120 1.560 ENSMUST00000171838.1
 Calcoco1
calcium binding and coiled coil domain 1
chr1_-_138847579 1.439 ENSMUST00000093486.3
ENSMUST00000046870.6
 Lhx9

LIM homeobox protein 9

chr7_-_28766469 1.425 ENSMUST00000085851.5
ENSMUST00000032815.4
 Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

chr3_+_106721893 1.300 ENSMUST00000106736.2
ENSMUST00000154973.1
ENSMUST00000131330.1
ENSMUST00000150513.1
 Lrif1



ligand dependent nuclear receptor interacting factor 1



chr6_+_125039760 1.233 ENSMUST00000140131.1
ENSMUST00000032480.7
 Ing4

inhibitor of growth family, member 4

chr1_-_23383149 1.219 ENSMUST00000027343.5
 Ogfrl1
opioid growth factor receptor-like 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 6.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
1.1 3.4 GO:0021852 pyramidal neuron migration(GO:0021852)
0.0 3.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 3.1 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 3.0 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.6 2.9 GO:0007256 activation of JNKK activity(GO:0007256)
0.8 2.5 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 2.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.3 2.3 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.4 1.9 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 1.9 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.3 1.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.2 1.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2 1.2 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.2 1.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.4 1.1 GO:0070375 ERK5 cascade(GO:0070375)
0.0 1.1 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.1 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 1.0 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 1.0 GO:0010107 potassium ion import(GO:0010107)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.6 GO:0055037 recycling endosome(GO:0055037)
0.1 2.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 2.2 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.7 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 1.2 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.2 1.0 GO:1902636 kinociliary basal body(GO:1902636)
0.0 1.0 GO:0030315 T-tubule(GO:0030315)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.8 GO:0033010 paranodal junction(GO:0033010)
0.1 0.7 GO:0097255 R2TP complex(GO:0097255)
0.1 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.5 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.2 GO:0003713 transcription coactivator activity(GO:0003713)
0.1 3.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 2.9 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 2.7 GO:0043130 ubiquitin binding(GO:0043130)
0.4 2.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 2.5 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.6 2.3 GO:0038025 reelin receptor activity(GO:0038025)
0.2 2.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 1.9 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 1.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.2 1.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 1.1 GO:0004707 MAP kinase activity(GO:0004707)
0.2 1.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 0.9 GO:0050827 toxin receptor binding(GO:0050827)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 0.8 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.0 0.8 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.7 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)