Motif ID: Lhx4

Z-value: 0.929


Transcription factors associated with Lhx4:

Gene SymbolEntrez IDGene Name
Lhx4 ENSMUSG00000026468.8 Lhx4



Activity profile for motif Lhx4.

activity profile for motif Lhx4


Sorted Z-values histogram for motif Lhx4

Sorted Z-values for motif Lhx4



Network of associatons between targets according to the STRING database.



First level regulatory network of Lhx4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_48665098 11.040 ENSMUST00000118578.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr19_+_44493472 7.117 ENSMUST00000041163.4
Wnt8b
wingless related MMTV integration site 8b
chr4_+_136143497 6.821 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr7_-_49636847 6.764 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr3_+_122419772 5.276 ENSMUST00000029766.4
Bcar3
breast cancer anti-estrogen resistance 3
chr11_+_59306920 4.792 ENSMUST00000000128.3
ENSMUST00000108783.3
Wnt9a

wingless-type MMTV integration site 9A

chr5_-_62765618 4.446 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr9_+_72806874 4.000 ENSMUST00000055535.8
Prtg
protogenin homolog (Gallus gallus)
chr2_-_166155272 3.814 ENSMUST00000088086.3
Sulf2
sulfatase 2
chr7_-_37773555 3.626 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr15_-_56694525 3.567 ENSMUST00000050544.7
Has2
hyaluronan synthase 2
chr1_-_163289214 3.489 ENSMUST00000183691.1
Prrx1
paired related homeobox 1
chr2_-_166155624 3.400 ENSMUST00000109249.2
Sulf2
sulfatase 2
chr4_+_65124174 3.068 ENSMUST00000084501.3
Pappa
pregnancy-associated plasma protein A
chr2_-_28916412 2.708 ENSMUST00000050776.2
ENSMUST00000113849.1
Barhl1

BarH-like 1 (Drosophila)

chr7_-_45103747 2.701 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chr15_-_103215285 2.664 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
Cbx5


chromobox 5


chr12_-_73047179 2.660 ENSMUST00000050029.7
Six1
sine oculis-related homeobox 1
chr5_-_62766153 2.520 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_+_34592248 2.493 ENSMUST00000038149.6
Pbx2
pre B cell leukemia homeobox 2
chrX_+_150547375 2.490 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr17_-_24073479 2.466 ENSMUST00000017090.5
Kctd5
potassium channel tetramerisation domain containing 5
chr13_-_102905740 2.303 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr3_-_141982224 2.299 ENSMUST00000029948.8
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr1_+_153665666 2.272 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr10_-_37138863 2.222 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr13_-_102906046 2.177 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr2_+_83724397 2.167 ENSMUST00000028499.4
ENSMUST00000141725.1
ENSMUST00000111740.2
Itgav


integrin alpha V


chr2_-_73453918 2.157 ENSMUST00000102679.1
Wipf1
WAS/WASL interacting protein family, member 1
chr2_-_174346712 2.145 ENSMUST00000168292.1
Gm20721
predicted gene, 20721
chr17_-_48432723 2.104 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr9_+_120929216 2.064 ENSMUST00000130466.1
Ctnnb1
catenin (cadherin associated protein), beta 1
chr9_+_119063429 2.061 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr1_+_153665587 2.058 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr18_-_15403680 2.031 ENSMUST00000079081.6
Aqp4
aquaporin 4
chr1_+_153665627 2.011 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr2_-_28916668 2.010 ENSMUST00000113847.1
Barhl1
BarH-like 1 (Drosophila)
chr14_+_69347587 2.003 ENSMUST00000064831.5
Entpd4
ectonucleoside triphosphate diphosphohydrolase 4
chr19_+_5474681 1.981 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr7_-_37772868 1.970 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr1_-_89933290 1.846 ENSMUST00000036954.7
Gbx2
gastrulation brain homeobox 2
chr15_+_25752860 1.749 ENSMUST00000022882.5
ENSMUST00000135173.1
Myo10

myosin X

chr15_-_8710409 1.746 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr17_-_14694223 1.744 ENSMUST00000170872.1
Thbs2
thrombospondin 2
chr8_-_46294592 1.729 ENSMUST00000058636.7
Helt
helt bHLH transcription factor
chr19_+_38395980 1.714 ENSMUST00000054098.2
Slc35g1
solute carrier family 35, member G1
chr11_+_109543694 1.692 ENSMUST00000106696.1
Arsg
arylsulfatase G
chr6_+_29859662 1.692 ENSMUST00000128927.2
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr16_-_22161450 1.687 ENSMUST00000115379.1
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr6_+_29859686 1.679 ENSMUST00000134438.1
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr8_-_61902669 1.673 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr1_+_106171752 1.666 ENSMUST00000061047.6
Phlpp1
PH domain and leucine rich repeat protein phosphatase 1
chrX_-_139871637 1.656 ENSMUST00000033811.7
ENSMUST00000087401.5
Morc4

microrchidia 4

chr15_-_64922290 1.624 ENSMUST00000023007.5
Adcy8
adenylate cyclase 8
chr4_-_3938354 1.600 ENSMUST00000003369.3
Plag1
pleiomorphic adenoma gene 1
chr9_+_64281575 1.594 ENSMUST00000034964.6
Tipin
timeless interacting protein
chr7_-_37769624 1.562 ENSMUST00000175941.1
Zfp536
zinc finger protein 536
chr6_+_29859374 1.559 ENSMUST00000115238.3
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr15_-_42676967 1.549 ENSMUST00000022921.5
Angpt1
angiopoietin 1
chr15_-_8710734 1.517 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_-_39359128 1.495 ENSMUST00000056409.2
Gm9845
predicted pseudogene 9845
chr10_+_75037066 1.489 ENSMUST00000147802.1
ENSMUST00000020391.5
Rab36

RAB36, member RAS oncogene family

chr10_+_75037291 1.467 ENSMUST00000139384.1
Rab36
RAB36, member RAS oncogene family
chr1_+_167598450 1.460 ENSMUST00000111386.1
ENSMUST00000111384.1
Rxrg

retinoid X receptor gamma

chr9_-_71896047 1.449 ENSMUST00000184448.1
Tcf12
transcription factor 12
chrX_-_102157065 1.447 ENSMUST00000056904.2
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chrX_+_169685191 1.444 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr1_-_72284248 1.413 ENSMUST00000097698.4
ENSMUST00000027381.6
Pecr

peroxisomal trans-2-enoyl-CoA reductase

chr4_-_58499398 1.413 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr11_-_89418948 1.393 ENSMUST00000050983.1
4932411E22Rik
RIKEN cDNA 4932411E22 gene
chr12_+_38783455 1.362 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr3_-_67515487 1.319 ENSMUST00000178314.1
ENSMUST00000054825.4
Rarres1

retinoic acid receptor responder (tazarotene induced) 1

chr12_+_38783503 1.318 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr10_-_40302186 1.300 ENSMUST00000099945.4
Amd1
S-adenosylmethionine decarboxylase 1
chr12_+_59013379 1.280 ENSMUST00000021379.7
Gemin2
gem (nuclear organelle) associated protein 2
chr17_-_78684262 1.194 ENSMUST00000145480.1
Strn
striatin, calmodulin binding protein
chr11_+_58171648 1.160 ENSMUST00000020820.1
Mrpl22
mitochondrial ribosomal protein L22
chr2_+_132847719 1.157 ENSMUST00000124836.1
ENSMUST00000154160.1
Crls1

cardiolipin synthase 1

chr5_-_28210168 1.145 ENSMUST00000117098.1
Cnpy1
canopy 1 homolog (zebrafish)
chr6_-_115037824 1.126 ENSMUST00000174848.1
ENSMUST00000032461.5
Tamm41

TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae)

chr1_-_127840290 1.126 ENSMUST00000061512.2
Map3k19
mitogen-activated protein kinase kinase kinase 19
chr10_+_37139558 1.121 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr5_+_9266097 1.118 ENSMUST00000134991.1
ENSMUST00000069538.7
ENSMUST00000115348.2
9330182L06Rik


RIKEN cDNA 9330182L06 gene


chr6_-_13871459 1.110 ENSMUST00000155856.1
2610001J05Rik
RIKEN cDNA 2610001J05 gene
chr13_-_95250166 1.105 ENSMUST00000162153.1
ENSMUST00000160957.2
ENSMUST00000159598.1
ENSMUST00000162412.1
Pde8b



phosphodiesterase 8B



chr5_-_28210022 1.094 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr1_+_167598384 1.084 ENSMUST00000015987.3
Rxrg
retinoid X receptor gamma
chr12_+_38780284 1.069 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr1_-_162866502 1.064 ENSMUST00000046049.7
Fmo1
flavin containing monooxygenase 1
chr17_+_82539258 1.048 ENSMUST00000097278.3
Gm6594
predicted pseudogene 6594
chr18_+_34758890 1.036 ENSMUST00000049281.5
Fam53c
family with sequence similarity 53, member C
chr15_+_31224371 1.033 ENSMUST00000044524.9
Dap
death-associated protein
chr6_+_34029421 1.028 ENSMUST00000070189.3
ENSMUST00000101564.2
Lrguk

leucine-rich repeats and guanylate kinase domain containing

chr4_+_95557494 0.992 ENSMUST00000079223.4
ENSMUST00000177394.1
Fggy

FGGY carbohydrate kinase domain containing

chr15_-_50889691 0.977 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr4_-_119294520 0.972 ENSMUST00000079644.6
Ybx1
Y box protein 1
chr5_-_70842617 0.969 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr4_-_97778042 0.931 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr3_-_59220150 0.915 ENSMUST00000170388.1
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr1_-_185329331 0.899 ENSMUST00000027921.4
ENSMUST00000110975.1
ENSMUST00000110974.3
Iars2


isoleucine-tRNA synthetase 2, mitochondrial


chr5_-_3647806 0.884 ENSMUST00000119783.1
ENSMUST00000007559.8
Gatad1

GATA zinc finger domain containing 1

chr6_+_145934113 0.884 ENSMUST00000032383.7
Sspn
sarcospan
chr3_-_49757257 0.878 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr3_+_102734496 0.867 ENSMUST00000029451.5
Tspan2
tetraspanin 2
chr16_-_56024628 0.854 ENSMUST00000119981.1
ENSMUST00000096021.3
Pcnp

PEST proteolytic signal containing nuclear protein

chr5_-_5266038 0.830 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
Cdk14


cyclin-dependent kinase 14


chrX_-_74246364 0.829 ENSMUST00000130007.1
Flna
filamin, alpha
chrX_+_16619698 0.827 ENSMUST00000026013.5
Maoa
monoamine oxidase A
chr1_-_93445642 0.804 ENSMUST00000042498.7
Hdlbp
high density lipoprotein (HDL) binding protein
chrX_-_160138375 0.801 ENSMUST00000033662.8
Pdha1
pyruvate dehydrogenase E1 alpha 1
chr17_-_67950908 0.784 ENSMUST00000164647.1
Arhgap28
Rho GTPase activating protein 28
chr2_+_163658370 0.736 ENSMUST00000164399.1
ENSMUST00000064703.6
ENSMUST00000099105.2
ENSMUST00000152418.1
ENSMUST00000126182.1
ENSMUST00000131228.1
Pkig





protein kinase inhibitor, gamma





chr5_+_15516489 0.735 ENSMUST00000178227.1
Gm21847
predicted gene, 21847
chr6_+_113333304 0.734 ENSMUST00000147945.1
Ogg1
8-oxoguanine DNA-glycosylase 1
chr10_-_35711891 0.723 ENSMUST00000080898.2
Amd2
S-adenosylmethionine decarboxylase 2
chr3_+_66985700 0.722 ENSMUST00000046542.6
ENSMUST00000162693.1
Rsrc1

arginine/serine-rich coiled-coil 1

chr16_-_45844303 0.714 ENSMUST00000036355.6
Phldb2
pleckstrin homology-like domain, family B, member 2
chr16_-_45844228 0.697 ENSMUST00000076333.5
Phldb2
pleckstrin homology-like domain, family B, member 2
chr10_-_64090241 0.696 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr12_+_38780817 0.685 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr14_+_74735641 0.679 ENSMUST00000177283.1
Esd
esterase D/formylglutathione hydrolase
chr13_-_89742244 0.673 ENSMUST00000109543.2
ENSMUST00000159337.1
ENSMUST00000159910.1
ENSMUST00000109544.2
Vcan



versican



chr7_-_45830776 0.673 ENSMUST00000107723.2
ENSMUST00000131384.1
Grwd1

glutamate-rich WD repeat containing 1

chr7_+_100159241 0.668 ENSMUST00000032967.3
Lipt2
lipoyl(octanoyl) transferase 2 (putative)
chr9_+_96258697 0.666 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chr7_+_140941550 0.662 ENSMUST00000079403.4
Athl1
ATH1, acid trehalase-like 1 (yeast)
chr1_-_82586781 0.638 ENSMUST00000087050.5
Col4a4
collagen, type IV, alpha 4
chr15_+_81744848 0.619 ENSMUST00000109554.1
Zc3h7b
zinc finger CCCH type containing 7B
chr13_-_97747373 0.619 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr2_-_33718789 0.617 ENSMUST00000130532.1
9430024E24Rik
RIKEN cDNA 9430024E24 gene
chr2_-_109280718 0.601 ENSMUST00000147770.1
Mettl15
methyltransferase like 15
chr14_+_26122609 0.591 ENSMUST00000100810.6
Duxbl2
doubl homeobox B-like 2
chr7_-_38019505 0.590 ENSMUST00000085513.4
Uri1
URI1, prefoldin-like chaperone
chr11_+_60537978 0.586 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr17_+_46650328 0.561 ENSMUST00000043464.7
Cul7
cullin 7
chr2_+_153161303 0.550 ENSMUST00000089027.2
Tm9sf4
transmembrane 9 superfamily protein member 4
chr9_+_100597686 0.545 ENSMUST00000124487.1
Stag1
stromal antigen 1
chr5_+_96209463 0.540 ENSMUST00000117766.1
Mrpl1
mitochondrial ribosomal protein L1
chr3_+_24333046 0.531 ENSMUST00000077389.6
Gm7536
predicted gene 7536
chr6_-_136941887 0.522 ENSMUST00000111891.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr19_+_46397009 0.519 ENSMUST00000118440.1
Sufu
suppressor of fused homolog (Drosophila)
chr13_-_58354862 0.515 ENSMUST00000043605.5
Kif27
kinesin family member 27
chr4_+_147492417 0.508 ENSMUST00000105721.2
Gm13152
predicted gene 13152
chr3_-_66296807 0.505 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr11_-_31671727 0.495 ENSMUST00000109415.1
Bod1
biorientation of chromosomes in cell division 1
chr11_-_31671863 0.488 ENSMUST00000058060.7
Bod1
biorientation of chromosomes in cell division 1
chr16_-_44016387 0.481 ENSMUST00000036174.3
Gramd1c
GRAM domain containing 1C
chr17_-_56036546 0.449 ENSMUST00000003268.9
Sh3gl1
SH3-domain GRB2-like 1
chr6_+_38381469 0.424 ENSMUST00000162554.1
ENSMUST00000161751.1
Ttc26

tetratricopeptide repeat domain 26

chr16_-_16829276 0.419 ENSMUST00000023468.5
Spag6
sperm associated antigen 6
chr17_-_26099257 0.412 ENSMUST00000053575.3
Gm8186
predicted gene 8186
chr19_+_46396885 0.411 ENSMUST00000039922.6
ENSMUST00000111867.2
ENSMUST00000120778.1
Sufu


suppressor of fused homolog (Drosophila)


chr16_-_90810365 0.392 ENSMUST00000140920.1
Urb1
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr19_+_10015016 0.385 ENSMUST00000137637.1
ENSMUST00000149967.1
Rab3il1

RAB3A interacting protein (rabin3)-like 1

chr6_+_7555053 0.383 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chrX_-_74246534 0.378 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr4_+_15881255 0.364 ENSMUST00000029876.1
Calb1
calbindin 1
chr11_-_4095344 0.335 ENSMUST00000004868.5
Mtfp1
mitochondrial fission process 1
chr9_+_72958785 0.319 ENSMUST00000098567.2
ENSMUST00000034734.8
Dyx1c1

dyslexia susceptibility 1 candidate 1 homolog (human)

chr5_+_96210115 0.310 ENSMUST00000036437.6
ENSMUST00000121477.1
Mrpl1

mitochondrial ribosomal protein L1

chr18_-_56975333 0.296 ENSMUST00000139243.2
ENSMUST00000025488.8
C330018D20Rik

RIKEN cDNA C330018D20 gene

chr2_-_170194033 0.291 ENSMUST00000180625.1
Gm17619
predicted gene, 17619
chr10_-_64090265 0.291 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr14_-_96519067 0.268 ENSMUST00000022666.7
Klhl1
kelch-like 1
chr10_-_63927434 0.256 ENSMUST00000079279.3
Gm10118
predicted gene 10118
chr8_-_21906412 0.247 ENSMUST00000051965.4
Defb11
defensin beta 11
chr13_-_83729544 0.240 ENSMUST00000181705.1
Gm26803
predicted gene, 26803
chr2_+_36230426 0.205 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr16_+_43235856 0.195 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr10_-_62507737 0.185 ENSMUST00000020271.6
Srgn
serglycin
chr17_-_46031813 0.172 ENSMUST00000024747.7
Vegfa
vascular endothelial growth factor A
chr7_-_46667375 0.141 ENSMUST00000107669.2
Tph1
tryptophan hydroxylase 1
chr8_+_13869641 0.139 ENSMUST00000051870.7
ENSMUST00000128557.1
Champ1

chromosome alignment maintaining phosphoprotein 1

chr1_-_152625212 0.132 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr1_-_168432270 0.131 ENSMUST00000072863.4
Pbx1
pre B cell leukemia homeobox 1
chr6_+_40471352 0.131 ENSMUST00000114779.2
ENSMUST00000031971.6
ENSMUST00000121360.1
ENSMUST00000117411.1
ENSMUST00000117830.1
Ssbp1




single-stranded DNA binding protein 1




chr1_+_63176818 0.121 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr14_-_104522615 0.118 ENSMUST00000022716.2
Rnf219
ring finger protein 219
chr5_-_17888884 0.115 ENSMUST00000169095.1
Cd36
CD36 antigen
chr9_+_108339048 0.108 ENSMUST00000082429.5
Gpx1
glutathione peroxidase 1
chr2_-_112480817 0.084 ENSMUST00000099589.2
Chrm5
cholinergic receptor, muscarinic 5
chr11_+_82781108 0.082 ENSMUST00000092849.5
ENSMUST00000021039.5
ENSMUST00000080461.5
ENSMUST00000173347.1
ENSMUST00000173727.1
ENSMUST00000173009.1
ENSMUST00000131537.2
ENSMUST00000173722.1
Lig3







ligase III, DNA, ATP-dependent







chr3_-_116711820 0.054 ENSMUST00000153108.1
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr2_-_148046896 0.050 ENSMUST00000172928.1
ENSMUST00000047315.3
Foxa2

forkhead box A2

chr6_+_34780412 0.039 ENSMUST00000115016.1
ENSMUST00000115017.1
Agbl3

ATP/GTP binding protein-like 3

chr2_-_160619971 0.036 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr7_-_5014645 0.029 ENSMUST00000165320.1
Fiz1
Flt3 interacting zinc finger protein 1
chr2_-_72986716 0.011 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr6_+_136518820 0.006 ENSMUST00000032335.6
Atf7ip
activating transcription factor 7 interacting protein
chr8_+_110618577 0.001 ENSMUST00000034190.9
Vac14
Vac14 homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 11.0 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.8 7.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.9 3.6 GO:1900623 positive regulation of keratinocyte proliferation(GO:0010838) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.9 2.7 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.8 3.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.7 2.2 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.7 2.1 GO:0060423 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023) negative regulation of mitotic cell cycle, embryonic(GO:0045976) foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963) regulation of histone demethylase activity (H3-K4 specific)(GO:1904173)
0.7 2.0 GO:0006597 spermine biosynthetic process(GO:0006597)
0.7 2.0 GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.6 4.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.6 1.8 GO:0021546 rhombomere development(GO:0021546)
0.6 2.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.6 1.7 GO:1990034 calcium ion export from cell(GO:1990034)
0.5 1.5 GO:0030210 heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)
0.5 6.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.5 7.7 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.4 7.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.4 2.0 GO:0070295 renal water absorption(GO:0070295)
0.4 1.1 GO:0035106 operant conditioning(GO:0035106)
0.4 1.4 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.3 3.5 GO:0048664 neuron fate determination(GO:0048664)
0.3 1.7 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) negative regulation of protein kinase C signaling(GO:0090038)
0.3 0.9 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.3 0.9 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.3 0.9 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.3 0.8 GO:0042420 dopamine catabolic process(GO:0042420)
0.3 6.8 GO:0071398 cellular response to fatty acid(GO:0071398)
0.2 1.2 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.2 1.6 GO:0048478 replication fork protection(GO:0048478)
0.2 0.7 GO:0009106 lipoate metabolic process(GO:0009106)
0.2 0.8 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 1.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.2 4.8 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.2 0.4 GO:0046878 regulation of saliva secretion(GO:0046877) positive regulation of saliva secretion(GO:0046878)
0.2 0.7 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.2 1.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.2 1.7 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.2 4.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.6 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 2.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.4 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.1 2.1 GO:0080111 DNA demethylation(GO:0080111)
0.1 2.5 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 4.0 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 0.8 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.6 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 1.7 GO:0071803 keratinocyte development(GO:0003334) positive regulation of podosome assembly(GO:0071803)
0.1 2.2 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.1 1.6 GO:0060736 prostate gland growth(GO:0060736)
0.1 1.1 GO:0009404 toxin metabolic process(GO:0009404)
0.1 0.7 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.1 0.5 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.2 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 1.4 GO:0030497 fatty acid elongation(GO:0030497)
0.1 0.1 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298)
0.1 2.6 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 0.6 GO:0070475 rRNA base methylation(GO:0070475)
0.1 1.0 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 2.0 GO:0007616 long-term memory(GO:0007616)
0.1 0.9 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 1.0 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 3.1 GO:0051384 response to glucocorticoid(GO:0051384)
0.0 0.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 2.1 GO:0051693 actin filament capping(GO:0051693)
0.0 0.8 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 1.0 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.1 GO:2000334 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 4.8 GO:0007605 sensory perception of sound(GO:0007605)
0.0 1.3 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 1.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.7 GO:0046677 response to antibiotic(GO:0046677)
0.0 1.0 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.8 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.6 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 1.7 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.1 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.0 0.1 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 8.1 GO:0016055 Wnt signaling pathway(GO:0016055) cell-cell signaling by wnt(GO:0198738)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 1.4 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.1 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0042585 germinal vesicle(GO:0042585)
0.7 2.2 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.3 2.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.2 1.2 GO:0031523 Myb complex(GO:0031523)
0.2 1.0 GO:0002177 manchette(GO:0002177)
0.2 1.7 GO:0031091 platelet alpha granule(GO:0031091)
0.2 3.3 GO:0043205 fibril(GO:0043205)
0.2 0.6 GO:1990393 3M complex(GO:1990393)
0.2 0.8 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 6.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 1.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 1.3 GO:0032797 SMN complex(GO:0032797)
0.1 0.6 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 2.7 GO:0010369 chromocenter(GO:0010369)
0.1 0.8 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 1.4 GO:0045180 basal cortex(GO:0045180)
0.1 1.7 GO:0002102 podosome(GO:0002102)
0.1 0.7 GO:0030312 external encapsulating structure(GO:0030312)
0.1 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.0 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 14.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 2.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 2.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.7 GO:0016459 myosin complex(GO:0016459)
0.0 6.0 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0097413 Lewy body(GO:0097413)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 1.5 GO:0005902 microvillus(GO:0005902)
0.0 2.2 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 1.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 2.6 GO:0000776 kinetochore(GO:0000776)
0.0 2.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.5 GO:0005871 kinesin complex(GO:0005871)
0.0 1.9 GO:0072372 primary cilium(GO:0072372)
0.0 1.4 GO:0030139 endocytic vesicle(GO:0030139)
0.0 1.5 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 7.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.2 3.6 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.9 2.7 GO:0019770 IgG receptor activity(GO:0019770)
0.7 4.9 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.7 3.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.5 2.0 GO:0019808 polyamine binding(GO:0019808)
0.5 7.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.5 1.4 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.4 2.2 GO:0019960 C-X3-C chemokine binding(GO:0019960) neuregulin binding(GO:0038132)
0.4 2.5 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.4 1.7 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.4 1.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.3 1.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.3 0.9 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.3 11.9 GO:0005109 frizzled binding(GO:0005109)
0.3 2.1 GO:1990188 euchromatin binding(GO:1990188)
0.3 2.0 GO:0015288 porin activity(GO:0015288)
0.3 2.0 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.3 1.6 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.3 2.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 0.7 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.2 1.4 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.2 1.2 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.2 0.7 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.2 1.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 0.8 GO:0051378 primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.2 6.9 GO:0005504 fatty acid binding(GO:0005504)
0.2 2.5 GO:0016594 glycine binding(GO:0016594)
0.2 5.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 4.9 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.6 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 7.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.8 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.9 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.6 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 1.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 1.0 GO:0070513 death domain binding(GO:0070513)
0.1 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 1.0 GO:0042556 cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 1.0 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.0 0.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 1.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.5 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 2.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.8 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 3.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.3 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 1.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.7 GO:0044653 trehalase activity(GO:0015927) dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.0 1.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 6.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.8 GO:0030332 cyclin binding(GO:0030332)
0.0 0.7 GO:0016415 octanoyltransferase activity(GO:0016415)
0.0 1.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.8 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0 3.2 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 3.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.1 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)