Motif ID: Mafb

Z-value: 0.768


Transcription factors associated with Mafb:

Gene SymbolEntrez IDGene Name
Mafb ENSMUSG00000074622.3 Mafb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafbmm10_v2_chr2_-_160367057_1603670730.602.6e-04Click!


Activity profile for motif Mafb.

activity profile for motif Mafb


Sorted Z-values histogram for motif Mafb

Sorted Z-values for motif Mafb



Network of associatons between targets according to the STRING database.



First level regulatory network of Mafb

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_130936172 5.724 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr6_+_120773633 4.002 ENSMUST00000112682.2
 Slc25a18
solute carrier family 25 (mitochondrial carrier), member 18
chr1_-_5070281 3.626 ENSMUST00000147158.1
ENSMUST00000118000.1
 Rgs20

regulator of G-protein signaling 20

chr2_+_170731807 3.112 ENSMUST00000029075.4
 Dok5
docking protein 5
chr1_+_9547948 2.927 ENSMUST00000144177.1
 Adhfe1
alcohol dehydrogenase, iron containing, 1
chr2_-_127482499 2.733 ENSMUST00000088538.5
 Kcnip3
Kv channel interacting protein 3, calsenilin
chr15_+_82252397 2.708 ENSMUST00000136948.1
 1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr4_+_102421518 2.558 ENSMUST00000106904.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr5_+_140735526 2.329 ENSMUST00000120630.2
 Amz1
archaelysin family metallopeptidase 1
chr10_+_40349265 2.328 ENSMUST00000044672.4
ENSMUST00000095743.2
 Cdk19

cyclin-dependent kinase 19

chr3_+_94398517 2.254 ENSMUST00000050975.3
 Lingo4
leucine rich repeat and Ig domain containing 4
chr19_-_5510467 2.204 ENSMUST00000070172.4
 Snx32
sorting nexin 32
chr16_-_52452654 2.188 ENSMUST00000168071.1
 Alcam
activated leukocyte cell adhesion molecule
chr14_+_118787894 2.075 ENSMUST00000047761.6
ENSMUST00000071546.7
 Cldn10

claudin 10

chr7_-_141010759 1.956 ENSMUST00000026565.6
 Ifitm3
interferon induced transmembrane protein 3
chr2_-_168741898 1.942 ENSMUST00000109176.1
ENSMUST00000178504.1
 Atp9a

ATPase, class II, type 9A

chr2_-_84425258 1.835 ENSMUST00000074262.2
 Calcrl
calcitonin receptor-like
chr9_-_48911067 1.831 ENSMUST00000003826.7
 Htr3a
5-hydroxytryptamine (serotonin) receptor 3A
chr19_+_26753588 1.796 ENSMUST00000177116.1
 Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr18_-_31820413 1.790 ENSMUST00000165131.2
 Gm6665
predicted gene 6665

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 101 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 5.7 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.3 3.6 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.3 3.1 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 2.8 GO:0006818 hydrogen transport(GO:0006818)
0.1 2.7 GO:0048266 behavioral response to pain(GO:0048266)
0.2 2.6 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.5 2.5 GO:0051547 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.1 2.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 2.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 2.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 2.2 GO:0016050 vesicle organization(GO:0016050)
0.3 2.0 GO:1905206 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.1 2.0 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.6 1.9 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.6 1.8 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.5 1.8 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.2 1.8 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 1.8 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.4 1.7 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0 1.7 GO:0006342 chromatin silencing(GO:0006342)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.8 GO:0031012 extracellular matrix(GO:0031012)
0.1 3.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 2.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 2.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.3 GO:0060077 inhibitory synapse(GO:0060077)
0.1 2.2 GO:0042101 T cell receptor complex(GO:0042101)
0.2 2.0 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 1.9 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 1.9 GO:0034703 cation channel complex(GO:0034703)
0.2 1.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.6 GO:0005922 connexon complex(GO:0005922)
0.3 1.5 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 1.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.4 GO:0071564 npBAF complex(GO:0071564)
0.1 1.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.2 1.1 GO:0042825 TAP complex(GO:0042825)
0.0 1.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.0 GO:0005771 multivesicular body(GO:0005771)
0.1 0.9 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.8 GO:0000145 exocyst(GO:0000145)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 5.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 3.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 3.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 3.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 3.0 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 2.9 GO:0015293 symporter activity(GO:0015293)
0.0 2.8 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.1 2.6 GO:0030552 cAMP binding(GO:0030552)
0.3 2.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 2.3 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors(GO:0016614)
0.1 2.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 2.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 2.0 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 1.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.9 GO:0043236 laminin binding(GO:0043236)
0.6 1.8 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.6 1.8 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.5 1.8 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.5 1.8 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589)
0.1 1.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)