Motif ID: Maz_Zfp281

Z-value: 1.038

Transcription factors associated with Maz_Zfp281:

Gene SymbolEntrez IDGene Name
Maz ENSMUSG00000030678.6 Maz
Zfp281 ENSMUSG00000041483.8 Zfp281

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mazmm10_v2_chr7_-_127026479_127026496-0.125.1e-01Click!
Zfp281mm10_v2_chr1_+_136624901_1366249490.009.9e-01Click!


Activity profile for motif Maz_Zfp281.

activity profile for motif Maz_Zfp281


Sorted Z-values histogram for motif Maz_Zfp281

Sorted Z-values for motif Maz_Zfp281



Network of associatons between targets according to the STRING database.



First level regulatory network of Maz_Zfp281

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_144939823 3.795 ENSMUST00000093962.4
 Ccnd1
cyclin D1
chr10_-_127341583 3.570 ENSMUST00000026474.3
 Gli1
GLI-Kruppel family member GLI1
chr2_-_147186389 3.564 ENSMUST00000109970.3
ENSMUST00000067075.5
 Nkx2-2

NK2 homeobox 2

chr12_+_33957645 3.126 ENSMUST00000049089.5
 Twist1
twist basic helix-loop-helix transcription factor 1
chr11_+_88718442 3.105 ENSMUST00000138007.1
 C030037D09Rik
RIKEN cDNA C030037D09 gene
chr6_+_4505493 2.947 ENSMUST00000031668.8
 Col1a2
collagen, type I, alpha 2
chr10_-_120476469 2.752 ENSMUST00000072777.7
ENSMUST00000159699.1
 Hmga2

high mobility group AT-hook 2

chr6_-_72390659 2.744 ENSMUST00000059983.9
 Vamp8
vesicle-associated membrane protein 8
chr2_-_80447625 2.659 ENSMUST00000028389.3
 Frzb
frizzled-related protein
chr16_+_84774123 2.571 ENSMUST00000114195.1
 Jam2
junction adhesion molecule 2
chr8_-_80057989 2.535 ENSMUST00000079038.2
 Hhip
Hedgehog-interacting protein
chr8_-_87959560 2.520 ENSMUST00000109655.2
 Zfp423
zinc finger protein 423
chr14_-_52316323 2.502 ENSMUST00000135523.1
 Sall2
sal-like 2 (Drosophila)
chrX_-_106485367 2.445 ENSMUST00000140707.1
 Fndc3c1
fibronectin type III domain containing 3C1
chr2_-_181039160 2.404 ENSMUST00000108851.1
 Chrna4
cholinergic receptor, nicotinic, alpha polypeptide 4
chr7_-_4515959 2.396 ENSMUST00000163710.1
ENSMUST00000166268.1
ENSMUST00000071798.6
ENSMUST00000178163.1
ENSMUST00000108587.2
 Tnnt1




troponin T1, skeletal, slow




chr7_-_142657466 2.369 ENSMUST00000097936.2
ENSMUST00000000033.5
 Igf2

insulin-like growth factor 2

chr11_-_88718165 2.369 ENSMUST00000107908.1
 Msi2
musashi RNA-binding protein 2
chr14_-_98169542 2.327 ENSMUST00000069334.7
ENSMUST00000071533.6
 Dach1

dachshund 1 (Drosophila)

chr3_+_131110350 2.235 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
 Lef1


lymphoid enhancer binding factor 1



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,150 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 10.1 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.2 7.9 GO:0070206 protein trimerization(GO:0070206)
0.4 6.3 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.7 5.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.5 5.9 GO:0043589 skin morphogenesis(GO:0043589)
0.3 5.5 GO:0060579 ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
1.1 5.3 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.2 5.1 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.4 5.0 GO:0001779 natural killer cell differentiation(GO:0001779)
0.5 4.9 GO:0010587 miRNA catabolic process(GO:0010587)
1.6 4.7 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.5 4.7 GO:0097421 liver regeneration(GO:0097421)
0.5 4.5 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
1.5 4.4 GO:1903048 regulation of acetylcholine-gated cation channel activity(GO:1903048)
0.5 4.4 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
1.4 4.3 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.0 4.3 GO:0051028 mRNA transport(GO:0051028)
0.5 4.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.2 4.2 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.8 4.1 GO:0035262 gonad morphogenesis(GO:0035262)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 343 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 23.2 GO:0031012 extracellular matrix(GO:0031012)
0.1 20.8 GO:0005667 transcription factor complex(GO:0005667)
0.3 17.1 GO:0005581 collagen trimer(GO:0005581)
0.0 13.7 GO:0005615 extracellular space(GO:0005615)
0.1 12.3 GO:0016324 apical plasma membrane(GO:0016324)
0.1 9.8 GO:0005844 polysome(GO:0005844)
0.2 8.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 7.6 GO:0005604 basement membrane(GO:0005604)
0.1 7.3 GO:0000791 euchromatin(GO:0000791)
0.6 6.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
1.9 5.8 GO:0005584 collagen type I trimer(GO:0005584)
0.0 5.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.4 5.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.4 4.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 4.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 4.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 3.8 GO:0005681 spliceosomal complex(GO:0005681)
0.3 3.7 GO:0097542 ciliary tip(GO:0097542)
0.7 3.6 GO:0005861 troponin complex(GO:0005861)
0.4 3.5 GO:0005642 annulate lamellae(GO:0005642)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 603 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 14.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 12.0 GO:0001159 core promoter proximal region DNA binding(GO:0001159)
0.1 11.4 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.7 10.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 7.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 7.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 6.8 GO:0008266 poly(U) RNA binding(GO:0008266)
0.3 6.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 6.3 GO:0071837 HMG box domain binding(GO:0071837)
0.2 6.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 5.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 5.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.4 5.4 GO:0015026 coreceptor activity(GO:0015026)
0.1 5.2 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.4 5.0 GO:0042166 acetylcholine binding(GO:0042166)
0.2 5.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 4.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 4.3 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.5 4.1 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.3 4.1 GO:0008307 structural constituent of muscle(GO:0008307)