Motif ID: Mbd2

Z-value: 1.478


Transcription factors associated with Mbd2:

Gene SymbolEntrez IDGene Name
Mbd2 ENSMUSG00000024513.10 Mbd2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mbd2mm10_v2_chr18_+_70568189_70568398-0.639.5e-05Click!


Activity profile for motif Mbd2.

activity profile for motif Mbd2


Sorted Z-values histogram for motif Mbd2

Sorted Z-values for motif Mbd2



Network of associatons between targets according to the STRING database.



First level regulatory network of Mbd2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_115194283 12.297 ENSMUST00000112113.1
 Cabp1
calcium binding protein 1
chr12_-_108003414 11.997 ENSMUST00000109887.1
ENSMUST00000109891.2
 Bcl11b

B cell leukemia/lymphoma 11B

chr5_+_37028329 6.417 ENSMUST00000173836.1
 Jakmip1
janus kinase and microtubule interacting protein 1
chr5_+_36868467 6.161 ENSMUST00000031003.7
 Ppp2r2c
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr17_-_47924460 5.952 ENSMUST00000113262.1
 Foxp4
forkhead box P4
chr17_-_47924400 5.884 ENSMUST00000113263.1
ENSMUST00000097311.2
 Foxp4

forkhead box P4

chr12_-_108003594 5.829 ENSMUST00000066060.4
 Bcl11b
B cell leukemia/lymphoma 11B
chr11_-_94474088 5.471 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
 Cacna1g










calcium channel, voltage-dependent, T type, alpha 1G subunit










chr14_-_55116935 4.604 ENSMUST00000022819.5
 Jph4
junctophilin 4
chr17_-_45549655 4.487 ENSMUST00000180252.1
 Tmem151b
transmembrane protein 151B
chr1_+_74854954 4.469 ENSMUST00000160379.2
 Cdk5r2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr2_+_28205648 4.131 ENSMUST00000102879.3
ENSMUST00000028177.4
 Olfm1

olfactomedin 1

chr13_-_52981027 3.791 ENSMUST00000071065.7
 Nfil3
nuclear factor, interleukin 3, regulated
chr5_-_135078224 3.770 ENSMUST00000067935.4
ENSMUST00000076203.2
 Vps37d

vacuolar protein sorting 37D (yeast)

chr4_+_133039482 3.561 ENSMUST00000105914.1
 Ahdc1
AT hook, DNA binding motif, containing 1
chr2_+_28193093 3.529 ENSMUST00000100244.3
 Olfm1
olfactomedin 1
chr2_+_28192971 3.384 ENSMUST00000113920.1
 Olfm1
olfactomedin 1
chr7_+_29303958 3.350 ENSMUST00000049977.6
 Dpf1
D4, zinc and double PHD fingers family 1
chr7_+_29303938 3.330 ENSMUST00000108231.1
 Dpf1
D4, zinc and double PHD fingers family 1
chr12_-_79007276 3.198 ENSMUST00000056660.6
ENSMUST00000174721.1
 Tmem229b

transmembrane protein 229B


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 149 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.0 17.8 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
1.3 14.3 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.1 12.0 GO:0050885 neuromuscular process controlling balance(GO:0050885)
1.0 11.0 GO:0023041 neuronal signal transduction(GO:0023041)
0.6 10.3 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
2.1 6.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 5.5 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 5.3 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.2 5.2 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
1.1 4.5 GO:0021586 pons maturation(GO:0021586)
0.9 4.5 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 3.8 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.9 3.4 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.4 3.1 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.6 3.0 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 3.0 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.1 3.0 GO:0035418 protein localization to synapse(GO:0035418)
0.0 3.0 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 2.8 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.9 2.7 GO:0021849 neuroblast division in subventricular zone(GO:0021849)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 89 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 11.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 10.8 GO:0000139 Golgi membrane(GO:0000139)
0.3 10.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.9 9.4 GO:0045298 tubulin complex(GO:0045298)
0.1 7.9 GO:0070382 exocytic vesicle(GO:0070382)
0.3 6.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 5.6 GO:0071565 nBAF complex(GO:0071565)
0.1 4.9 GO:0030175 filopodium(GO:0030175)
0.9 4.6 GO:0030314 junctional membrane complex(GO:0030314)
1.5 4.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
1.1 4.5 GO:1990032 parallel fiber(GO:1990032)
0.4 3.8 GO:0000813 ESCRT I complex(GO:0000813)
0.3 3.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 3.2 GO:0031225 anchored component of membrane(GO:0031225)
0.1 3.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 3.1 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 2.9 GO:0099738 cell cortex region(GO:0099738)
0.0 2.9 GO:0044450 microtubule organizing center part(GO:0044450)
0.1 2.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.3 2.7 GO:0005883 neurofilament(GO:0005883)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 113 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 12.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 10.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.4 9.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 7.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.4 7.3 GO:0050811 GABA receptor binding(GO:0050811)
0.4 6.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.4 6.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
1.4 5.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 5.0 GO:0005509 calcium ion binding(GO:0005509)
0.3 4.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 4.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.6 4.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.5 4.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.7 4.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 4.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 4.0 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.2 3.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 3.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 3.5 GO:0051087 chaperone binding(GO:0051087)
0.4 3.4 GO:0030274 LIM domain binding(GO:0030274)