Motif ID: Mecom

Z-value: 0.600


Transcription factors associated with Mecom:

Gene SymbolEntrez IDGene Name
Mecom ENSMUSG00000027684.10 Mecom



Activity profile for motif Mecom.

activity profile for motif Mecom


Sorted Z-values histogram for motif Mecom

Sorted Z-values for motif Mecom



Network of associatons between targets according to the STRING database.



First level regulatory network of Mecom

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 59 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_+_897782 6.008 ENSMUST00000055032.7
 Kdm5d
lysine (K)-specific demethylase 5D
chr7_-_103853199 4.397 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr1_+_152399824 2.834 ENSMUST00000044311.8
 Colgalt2
collagen beta(1-O)galactosyltransferase 2
chr1_+_45311538 2.675 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chr13_+_89540636 2.433 ENSMUST00000022108.7
 Hapln1
hyaluronan and proteoglycan link protein 1
chr6_+_138140298 2.247 ENSMUST00000008684.4
 Mgst1
microsomal glutathione S-transferase 1
chr10_+_3740348 1.707 ENSMUST00000120274.1
 Plekhg1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr1_+_156838915 1.415 ENSMUST00000111720.1
 Angptl1
angiopoietin-like 1
chr8_-_18741542 1.242 ENSMUST00000033846.6
 Angpt2
angiopoietin 2
chr2_+_103970221 1.028 ENSMUST00000111140.2
ENSMUST00000111139.2
 Lmo2

LIM domain only 2

chr2_+_103970115 0.954 ENSMUST00000111143.1
ENSMUST00000138815.1
 Lmo2

LIM domain only 2

chr16_-_38713235 0.927 ENSMUST00000023487.4
 Arhgap31
Rho GTPase activating protein 31
chr10_-_27616895 0.926 ENSMUST00000092639.5
 Lama2
laminin, alpha 2
chr9_+_72806874 0.873 ENSMUST00000055535.8
 Prtg
protogenin homolog (Gallus gallus)
chr2_+_103969528 0.734 ENSMUST00000123437.1
ENSMUST00000163256.1
 Lmo2

LIM domain only 2

chr16_-_29541483 0.695 ENSMUST00000057018.8
ENSMUST00000182627.1
 Atp13a4

ATPase type 13A4

chr14_+_115042752 0.638 ENSMUST00000134140.2
 Mir17hg
Mir17 host gene 1 (non-protein coding)
chr14_+_34375504 0.594 ENSMUST00000111908.1
 Mmrn2
multimerin 2
chrX_-_145505175 0.555 ENSMUST00000143610.1
 Amot
angiomotin
chr11_-_60046477 0.546 ENSMUST00000000310.7
ENSMUST00000102693.2
ENSMUST00000148512.1
 Pemt


phosphatidylethanolamine N-methyltransferase



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 6.0 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.9 4.4 GO:0015671 oxygen transport(GO:0015671)
0.5 2.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 2.7 GO:0097067 negative regulation of erythrocyte differentiation(GO:0045647) cellular response to thyroid hormone stimulus(GO:0097067)
0.0 2.5 GO:0098780 mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)
0.6 2.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.4 1.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 0.9 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.2 0.7 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.6 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 0.5 GO:0035878 nail development(GO:0035878)
0.1 0.5 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 0.5 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.3 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)

Gene overrepresentation in cellular_component category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 4.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 3.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 2.7 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 2.5 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.9 GO:0005605 basal lamina(GO:0005605)
0.0 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.5 GO:0043034 costamere(GO:0043034)
0.1 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)

Gene overrepresentation in molecular_function category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 6.0 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
1.1 4.4 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.0 2.8 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.2 2.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 2.7 GO:0043425 bHLH transcription factor binding(GO:0043425) E-box binding(GO:0070888)
0.1 2.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.2 0.7 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.7 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.1 0.5 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.3 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)