Motif ID: Mef2b

Z-value: 0.854


Transcription factors associated with Mef2b:

Gene SymbolEntrez IDGene Name
Mef2b ENSMUSG00000079033.3 Mef2b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mef2bmm10_v2_chr8_+_70152754_70152781-0.048.1e-01Click!


Activity profile for motif Mef2b.

activity profile for motif Mef2b


Sorted Z-values histogram for motif Mef2b

Sorted Z-values for motif Mef2b



Network of associatons between targets according to the STRING database.



First level regulatory network of Mef2b

PNG image of the network

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Top targets:


Showing 1 to 20 of 179 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103843154 13.039 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr6_-_23248264 6.718 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr7_-_142899985 5.303 ENSMUST00000000219.3
 Th
tyrosine hydroxylase
chr7_-_144738478 3.885 ENSMUST00000121758.1
 Ano1
anoctamin 1, calcium activated chloride channel
chr3_-_98814434 2.758 ENSMUST00000029463.6
 Hsd3b6
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6
chr2_-_94264713 2.691 ENSMUST00000129661.1
 E530001K10Rik
RIKEN cDNA E530001K10 gene
chr2_-_94264745 2.452 ENSMUST00000134563.1
 E530001K10Rik
RIKEN cDNA E530001K10 gene
chr2_+_120463566 2.227 ENSMUST00000028749.7
ENSMUST00000110721.1
 Capn3

calpain 3

chr17_-_58991343 2.195 ENSMUST00000025064.7
 2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr7_-_144738520 2.140 ENSMUST00000118556.2
ENSMUST00000033393.8
 Ano1

anoctamin 1, calcium activated chloride channel

chr9_-_110742577 1.895 ENSMUST00000006005.7
 Pth1r
parathyroid hormone 1 receptor
chrY_-_1286563 1.786 ENSMUST00000091190.5
 Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr7_-_102100227 1.756 ENSMUST00000106937.1
 Art5
ADP-ribosyltransferase 5
chr5_-_116422858 1.714 ENSMUST00000036991.4
 Hspb8
heat shock protein 8
chrX_-_93832106 1.671 ENSMUST00000045748.6
 Pdk3
pyruvate dehydrogenase kinase, isoenzyme 3
chr3_+_137341103 1.629 ENSMUST00000119475.1
 Emcn
endomucin
chr4_+_119108711 1.555 ENSMUST00000030398.3
 Slc2a1
solute carrier family 2 (facilitated glucose transporter), member 1
chr1_-_191183244 1.553 ENSMUST00000027941.8
 Atf3
activating transcription factor 3
chr11_+_94328242 1.479 ENSMUST00000021227.5
 Ankrd40
ankyrin repeat domain 40
chr3_-_150073620 1.407 ENSMUST00000057740.5
 Rpsa-ps10
ribosomal protein SA, pseudogene 10

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 83 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.6 13.0 GO:0015671 oxygen transport(GO:0015671)
1.1 6.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.2 6.0 GO:0015705 iodide transport(GO:0015705)
1.3 5.3 GO:0042414 epinephrine metabolic process(GO:0042414)
0.9 2.8 GO:0042908 xenobiotic transport(GO:0042908)
0.0 2.8 GO:0006694 steroid biosynthetic process(GO:0006694)
0.8 2.3 GO:1990481 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) snRNA pseudouridine synthesis(GO:0031120) mRNA pseudouridine synthesis(GO:1990481)
0.7 2.2 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 2.0 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.2 1.9 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 1.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.4 1.8 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 1.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.4 1.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.4 1.6 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.4 1.6 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 1.6 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.5 1.4 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 1.4 GO:0032611 interleukin-1 beta production(GO:0032611)
0.3 1.3 GO:0031033 myosin filament organization(GO:0031033)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 13.0 GO:0005833 hemoglobin complex(GO:0005833)
0.2 7.2 GO:0034707 chloride channel complex(GO:0034707)
0.2 5.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.3 3.3 GO:0001939 female pronucleus(GO:0001939)
0.6 2.3 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 2.3 GO:0005814 centriole(GO:0005814)
0.0 1.9 GO:0031526 brush border membrane(GO:0031526)
0.0 1.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.8 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.3 1.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.6 GO:0030018 Z disc(GO:0030018)
0.1 1.5 GO:0031528 microvillus membrane(GO:0031528)
0.1 1.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 1.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.2 GO:0030118 clathrin coat(GO:0030118)
0.3 0.9 GO:0045160 myosin I complex(GO:0045160)
0.2 0.9 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.8 GO:0008180 COP9 signalosome(GO:0008180)
0.2 0.7 GO:0005588 collagen type V trimer(GO:0005588)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.3 13.0 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.0 6.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
1.5 6.0 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.9 5.3 GO:0035240 dopamine binding(GO:0035240)
0.8 3.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.9 2.8 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.6 2.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.3 2.2 GO:0031432 titin binding(GO:0031432)
0.1 2.0 GO:0070402 NADPH binding(GO:0070402)
0.1 1.9 GO:0017046 peptide hormone binding(GO:0017046)
0.0 1.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.6 1.8 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.3 1.8 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 1.8 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.4 1.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.3 1.6 GO:0051525 NFAT protein binding(GO:0051525)
0.2 1.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 1.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 1.3 GO:0005523 tropomyosin binding(GO:0005523)