Motif ID: Meis1

Z-value: 0.908


Transcription factors associated with Meis1:

Gene SymbolEntrez IDGene Name
Meis1 ENSMUSG00000020160.12 Meis1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meis1mm10_v2_chr11_-_19018714_19018828-0.192.8e-01Click!


Activity profile for motif Meis1.

activity profile for motif Meis1


Sorted Z-values histogram for motif Meis1

Sorted Z-values for motif Meis1



Network of associatons between targets according to the STRING database.



First level regulatory network of Meis1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_139543889 6.642 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr9_+_87022014 4.108 ENSMUST00000168529.2
ENSMUST00000174724.1
ENSMUST00000173126.1
Cyb5r4


cytochrome b5 reductase 4


chr2_+_93642307 4.017 ENSMUST00000042078.3
ENSMUST00000111254.1
Alx4

aristaless-like homeobox 4

chr2_-_168767136 3.779 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr6_+_4747306 3.006 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
Peg10


paternally expressed 10


chr1_-_65051119 3.003 ENSMUST00000161960.1
ENSMUST00000087359.5
Cryge

crystallin, gamma E

chr4_-_41098174 2.946 ENSMUST00000055327.7
Aqp3
aquaporin 3
chr2_-_168767029 2.841 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr3_+_125404292 2.736 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr3_+_109123104 2.653 ENSMUST00000029477.6
Slc25a24
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24
chr14_-_98169542 2.527 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chr11_+_117986292 2.511 ENSMUST00000132676.1
Pgs1
phosphatidylglycerophosphate synthase 1
chr9_+_78051938 2.352 ENSMUST00000024104.7
Gcm1
glial cells missing homolog 1 (Drosophila)
chr11_+_85832551 2.351 ENSMUST00000000095.6
Tbx2
T-box 2
chr4_-_46404224 2.313 ENSMUST00000107764.2
Hemgn
hemogen
chr11_+_101316917 2.265 ENSMUST00000151385.1
Psme3
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr9_-_107985863 2.254 ENSMUST00000048568.4
Fam212a
family with sequence similarity 212, member A
chr7_-_143460989 2.197 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr8_+_127064022 2.159 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
Pard3


par-3 (partitioning defective 3) homolog (C. elegans)


chr3_+_107631322 2.123 ENSMUST00000106703.1
Gm10961
predicted gene 10961

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 121 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 6.6 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.4 6.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.7 4.1 GO:0003383 apical constriction(GO:0003383)
0.1 4.1 GO:0046677 response to antibiotic(GO:0046677)
0.2 4.0 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 3.0 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 3.0 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 3.0 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.7 2.9 GO:0015793 glycerol transport(GO:0015793)
0.0 2.9 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.5 2.7 GO:0015867 ATP transport(GO:0015867)
0.8 2.5 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 2.5 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.8 2.4 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.4 2.4 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 2.3 GO:0046847 filopodium assembly(GO:0046847)
0.1 2.2 GO:0060065 uterus development(GO:0060065)
0.0 2.2 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.2 2.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 2.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.4 GO:0005667 transcription factor complex(GO:0005667)
0.1 7.7 GO:0000792 heterochromatin(GO:0000792)
0.5 4.1 GO:0033269 internode region of axon(GO:0033269)
0.7 2.8 GO:0008537 proteasome activator complex(GO:0008537)
0.0 2.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 2.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.7 2.2 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.7 2.1 GO:0033186 CAF-1 complex(GO:0033186)
0.1 2.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.0 GO:0005643 nuclear pore(GO:0005643)
0.0 2.0 GO:0032587 ruffle membrane(GO:0032587)
0.2 1.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.9 GO:0016234 inclusion body(GO:0016234)
0.1 1.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.8 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.3 GO:0030686 90S preribosome(GO:0030686)
0.0 1.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.2 1.2 GO:0016461 unconventional myosin complex(GO:0016461)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 86 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 19.2 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.6 5.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 4.0 GO:0071837 HMG box domain binding(GO:0071837)
0.1 3.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 3.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 3.4 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 3.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 3.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.4 2.9 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.3 2.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.7 2.7 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.4 2.7 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 2.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.8 2.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 2.5 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 2.2 GO:0051015 actin filament binding(GO:0051015)
0.3 2.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 2.1 GO:0005504 fatty acid binding(GO:0005504)
0.3 2.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 2.0 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)